List of works - Gabi Kastenmüller

3D Shape Histograms for Similarity Search and Classification in Spatial Databases

A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population ⬇️

scientific article published on 8 October 2015

A cross-platform approach identifies genetic regulators of human metabolism and health

scientific article published on 07 January 2021

A genome-wide perspective of genetic variation in human metabolism

scientific article

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

scientific article published on 20 August 2019

A network-based conditional genetic association analysis of the human metabolome

scientific article published on 01 December 2018

A strategy to incorporate prior knowledge into correlation network cutoff selection

scientific article published on 14 October 2020

A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control

scientific article published on 7 June 2015

Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis

Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors

scientific article published on 19 July 2017

Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders

scientific article published on 25 January 2016

An atlas of genetic influences on human blood metabolites

scientific article

An environmental perspective on large-scale genome clustering based on metabolic capabilities

scientific article published in August 2008

An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker

scientific article published on 22 April 2015

Associations between adipose tissue volume and small molecules in plasma and urine among asymptomatic subjects from the general population

scientific article published on 30 January 2020

Associations between thyroid hormones and serum metabolite profiles in an euthyroid population

scientific article

Associations of maternal type 1 diabetes with childhood adiposity and metabolic health in the offspring: a prospective cohort study

article

Automated pathway and reaction prediction facilitates in silico identification of unknown metabolites in human cohort studies.

scientific article published on 4 April 2017

Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts

scientific article published on 17 October 2019

Biochemical insights from population studies with genetics and metabolomics

scientific article published on 30 September 2015

Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach

scientific article (publication date: December 2013)

Body fat free mass is associated with the serum metabolite profile in a population-based study

scientific article

CIDeR: multifactorial interaction networks in human diseases

scientific article

CYGD: the Comprehensive Yeast Genome Database

scientific article

Cardiovascular Risk Factors Associated With Blood Metabolite Concentrations and Their Alterations During a 4-Year Period in a Population-Based Cohort

scientific article

Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

scientific article published on 20 September 2018

Characterization of the metabolic profile associated with serum 25-hydroxyvitamin D: a cross-sectional analysis in population-based data

scientific article

Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations

scientific article published in Scientific Reports

Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele

article

Comprehensive Metabolic Profiling Reveals a Lipid-Rich Fingerprint of Free Thyroxine Far Beyond Classic Parameters

scientific article published on 01 May 2018

Comprehensive metabolic characterization of serum osteocalcin action in a large non-diabetic sample

scientific article published on 18 September 2017

Comprehensive metabolic profiling of chronic low-grade inflammation among generally healthy individuals

scientific article published on 30 November 2017

Connecting genetic risk to disease end points through the human blood plasma proteome

scientific article published on 27 February 2017

Datenbasierte Funktionsvorhersage krankheitsrelevanter genetischer Varianten

scholarly article by Matthias Arnold published in October 2018

Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.

scientific article published on 8 January 2018

Diagnostic and Prognostic Metabolites Identified for Joint Symptoms in the KORA Population

scientific article

Differences between human plasma and serum metabolite profiles

scientific article

Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance

scientific article

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

scientific article published on 5 August 2015

Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits

scientific article published on 06 September 2013

Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives

scientific article published on 26 October 2017

Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model

scientific article

From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.

scientific article published on 12 December 2017

Gender-specific pathway differences in the human serum metabolome

scientific article

Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms

scientific article

Genetic architecture of host proteins interacting with SARS-CoV-2

scientific article published on 01 July 2020

Genetic associations with lipoprotein subfractions provide information on their biological nature

scientific article

Genetic diagnosis of Mendelian disorders via RNA sequencing

scientific article published on 12 June 2017

Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans

scientific article published on 20 January 2020

Genetics of human metabolism: an update

scientific article

Genome-Wide Association Studies of Metabolite Concentrations (mGWAS): Relevance for Nephrology

scientific article published in March 2018

Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality

scientific article published on 9 September 2015

HSC-explorer: a curated database for hematopoietic stem cells

scientific article

Hepatic Steatosis Is Associated With Adverse Molecular Signatures in Subjects Without Diabetes

scientific article published on 01 October 2018

High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice

scientific article

HoPaCI-DB: host-Pseudomonas and Coxiella interaction database

scientific article published on 16 October 2013

Human metabolic individuality in biomedical and pharmaceutical research

scientific article (publication date: 31 August 2011)

Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma

scientific article published on 15 February 2013

Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up

scientific article published on 09 January 2014

Instability of personal human metabotype is linked to all-cause mortality.

scientific article published on 28 June 2018

Integration of 'omics' data in aging research: from biomarkers to systems biology

scientific article

Lactation is associated with altered metabolomic signatures in women with gestational diabetes

scientific article published on 16 July 2016

Ldlr and ApoE mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease

Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse

scientific article published on 9 December 2015

Long term conservation of human metabolic phenotypes and link to heritability

scientific article

Metabolic Fingerprints of Circulating IGF-1 and the IGF-1/IGFBP-3 Ratio: A Multifluid Metabolomics Study

scientific article

Metabolic network failures in Alzheimer's disease: A biochemical road map.

scientific article published on 21 March 2017

Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.

scientific article published on 23 September 2015

Metabolite profiling reveals new insights into the regulation of serum urate in humans

scientific article published on 20 July 2013

Metabolites of milk intake: a metabolomic approach in UK twins with findings replicated in two European cohorts.

scientific article published on 28 July 2016

Metabolomic Profiling of Long-Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain.

scientific article

Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate

scientific article published in June 2015

Metabolomic profiles in individuals with negative affectivity and social inhibition: a population-based study of Type D personality

scientific article published on 10 December 2012

Metabolomic profiling implicates adiponectin as mediator of a favorable lipoprotein profile associated with NT-proBNP

scientific article published on 28 August 2018

Metabolomics approach reveals effects of antihypertensives and lipid-lowering drugs on the human metabolism

scientific article

Metabolomics enables precision medicine: "A White Paper, Community Perspective"

scientific article

Metabolomics of Ramadan fasting: an opportunity for the controlled study of physiological responses to food intake

scientific article

Metabolomics signature associated with circulating serum selenoprotein P levels

scientific article published on 17 November 2018

Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy

scientific article published in December 2017

Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues

scientific article published on 12 September 2016

Mining the unknown: a systems approach to metabolite identification combining genetic and metabolic information

scientific article

MoDentify: phenotype-driven module identification in metabolomics networks at different resolutions

scientific article published on 19 July 2018

Molecular Fingerprints of Iron Parameters among a Population-Based Sample

scientific article published on 19 November 2018

Mouse phenotyping

scientific article

Multi-omic signature of body weight change: results from a population-based cohort study

scientific article

Network-based approach for analyzing intra- and interfluid metabolite associations in human blood, urine, and saliva

scientific article published on 9 December 2014

Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes

scientific article published on 12 July 2016

Nonadditive Effects of Genes in Human Metabolomics

scientific article published on 14 May 2015

PEDANT covers all complete RefSeq genomes

scientific article published on 21 October 2008

Phenotype-driven identification of modules in a hierarchical map of multifluid metabolic correlations

scientific article published on 21 September 2017

Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146

scientific article

Pre-analytical sample quality: metabolite ratios as an intrinsic marker for prolonged room temperature exposure of serum samples

scientific article published on 30 March 2015

Questionnaire-based self-reported nutrition habits associate with serum metabolism as revealed by quantitative targeted metabolomics

scientific article published on 30 November 2010

Response to Comment on Adam et al. Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues. Diabetes 2016;65:3776–3785

scientific article published on 01 May 2017

SNiPA: an interactive, genetic variant-centered annotation browser

scientific article published on 26 November 2014

Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample

scientific article published on 5 April 2017

Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome

scientific article published on 02 March 2020

Sex-specific metabolic profiles of androgens and its main binding protein SHBG in a middle aged population without diabetes

scientific article

Short-term NO2 exposure is associated with long-chain fatty acids in prospective cohorts from Augsburg, Germany: results from an analysis of 138 metabolites and three exposures.

scientific article published on 8 October 2016

Systems Biology Meets Metabolism

Targeted metabolomics and medication classification data from participants in the ADNI1 cohort

scientific article published on 17 October 2017

Taurine deficiency as a driver of aging

scientific article published on 08 June 2023

The HIB database of annotated UniGene clusters

article

The Human Blood Metabolome-Transcriptome Interface

scientific article published on 18 June 2015

The PEDANT genome database

scientific article

The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study

scientific article

The Saliva Metabolome in Association to Oral Health Status

scientific article published on 26 April 2019

The dynamic range of the human metabolome revealed by challenges

scientific article

The fecal metabolome as a functional readout of the gut microbiome

article

The human metabolic profile reflects macro- and micronutrient intake distinctly according to fasting time

scientific article published in Scientific Reports

Uncovering metabolic pathways relevant to phenotypic traits of microbial genomes

scientific article published on 10 March 2009

Urine Metabolite Profiles Predictive of Human Kidney Allograft Status

scientific article published on 5 June 2015

Variation in the human lipidome associated with coffee consumption as revealed by quantitative targeted metabolomics

scientific article published in November 2009

Vitamin E supplementation is associated with lower levels of C-reactive protein only in higher dosages and combined with other antioxidants: The Cooperative Health Research in the Region of Augsburg (KORA) F4 study

scientific article published on 21 April 2015

metaP-server: a web-based metabolomics data analysis tool

scientific article

pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms

scientific article published on 29 September 2017

List of works by Gabi Kastenmüller

3D Shape Histograms for Similarity Search and Classification in Spatial Databases

A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population ⬇️

A cross-platform approach identifies genetic regulators of human metabolism and health

A genome-wide perspective of genetic variation in human metabolism

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

A network-based conditional genetic association analysis of the human metabolome

A strategy to incorporate prior knowledge into correlation network cutoff selection

A systems view of type 2 diabetes-associated metabolic perturbations in saliva, blood and urine at different timescales of glycaemic control

Accelerated lipid catabolism and autophagy are cancer survival mechanisms under inhibited glutaminolysis

Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors

Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders

An atlas of genetic influences on human blood metabolites

An environmental perspective on large-scale genome clustering based on metabolic capabilities

An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker

Associations between adipose tissue volume and small molecules in plasma and urine among asymptomatic subjects from the general population

Associations between thyroid hormones and serum metabolite profiles in an euthyroid population

Associations of maternal type 1 diabetes with childhood adiposity and metabolic health in the offspring: a prospective cohort study

Automated pathway and reaction prediction facilitates in silico identification of unknown metabolites in human cohort studies.

Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts

Biochemical insights from population studies with genetics and metabolomics

Biomarkers for type 2 diabetes and impaired fasting glucose using a nontargeted metabolomics approach

Body fat free mass is associated with the serum metabolite profile in a population-based study

CIDeR: multifactorial interaction networks in human diseases

CYGD: the Comprehensive Yeast Genome Database

Cardiovascular Risk Factors Associated With Blood Metabolite Concentrations and Their Alterations During a 4-Year Period in a Population-Based Cohort

Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

Characterization of the metabolic profile associated with serum 25-hydroxyvitamin D: a cross-sectional analysis in population-based data

Circulating metabolic biomarkers of renal function in diabetic and non-diabetic populations

Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele

Comprehensive Metabolic Profiling Reveals a Lipid-Rich Fingerprint of Free Thyroxine Far Beyond Classic Parameters

Comprehensive metabolic characterization of serum osteocalcin action in a large non-diabetic sample

Comprehensive metabolic profiling of chronic low-grade inflammation among generally healthy individuals

Connecting genetic risk to disease end points through the human blood plasma proteome

Datenbasierte Funktionsvorhersage krankheitsrelevanter genetischer Varianten

Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation.

Diagnostic and Prognostic Metabolites Identified for Joint Symptoms in the KORA Population

Differences between human plasma and serum metabolite profiles

Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits

Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives

Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model

From Discovery to Translation: Characterization of C-Mannosyltryptophan and Pseudouridine as Markers of Kidney Function.

Gender-specific pathway differences in the human serum metabolome

Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms

Genetic architecture of host proteins interacting with SARS-CoV-2

Genetic associations with lipoprotein subfractions provide information on their biological nature

Genetic diagnosis of Mendelian disorders via RNA sequencing

Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans

Genetics of human metabolism: an update

Genome-Wide Association Studies of Metabolite Concentrations (mGWAS): Relevance for Nephrology

Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality

HSC-explorer: a curated database for hematopoietic stem cells

Hepatic Steatosis Is Associated With Adverse Molecular Signatures in Subjects Without Diabetes

High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice

HoPaCI-DB: host-Pseudomonas and Coxiella interaction database

Human metabolic individuality in biomedical and pharmaceutical research

Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma

Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up

Instability of personal human metabotype is linked to all-cause mortality.

Integration of 'omics' data in aging research: from biomarkers to systems biology

Lactation is associated with altered metabolomic signatures in women with gestational diabetes

Ldlr and ApoE mice better mimic the human metabolite signature of increased carotid intima media thickness compared to other animal models of cardiovascular disease

Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse

Long term conservation of human metabolic phenotypes and link to heritability

Metabolic Fingerprints of Circulating IGF-1 and the IGF-1/IGFBP-3 Ratio: A Multifluid Metabolomics Study

Metabolic network failures in Alzheimer's disease: A biochemical road map.

Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.

Metabolite profiling reveals new insights into the regulation of serum urate in humans

Metabolites of milk intake: a metabolomic approach in UK twins with findings replicated in two European cohorts.

Metabolomic Profiling of Long-Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain.

Metabolomic identification of a novel pathway of blood pressure regulation involving hexadecanedioate

Metabolomic profiles in individuals with negative affectivity and social inhibition: a population-based study of Type D personality

Metabolomic profiling implicates adiponectin as mediator of a favorable lipoprotein profile associated with NT-proBNP

Metabolomics approach reveals effects of antihypertensives and lipid-lowering drugs on the human metabolism

Metabolomics enables precision medicine: "A White Paper, Community Perspective"

Metabolomics of Ramadan fasting: an opportunity for the controlled study of physiological responses to food intake

Metabolomics signature associated with circulating serum selenoprotein P levels

Metabomatching: Using genetic association to identify metabolites in proton NMR spectroscopy