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List of works by Adam E. Snook

A novel CDX2 isoform regulates alternative splicing

scientific article

A novel role for Cish in the inhibition of TCR signaling

A uroguanylin-GUCY2C endocrine axis regulates feeding in mice

scientific article published on 25 August 2011

APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis

scientific article published on 09 February 2020

Adenovirus-Mediated ABCC6 Gene Therapy for Heritable Ectopic Mineralization Disorders

article

Advances in Chimeric Antigen Receptor T-Cell Therapies for Solid Tumors

Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics

scientific article

Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis

scientific article

Biodistribution and Pharmacokinetics Study of siRNA-loaded Anti-NTSR1-mAb-functionalized Novel Hybrid Nanoparticles in a Metastatic Orthotopic Murine Lung Cancer Model

scientific article published on 26 January 2016

CD19-Targeted Nanodelivery of Doxorubicin Enhances Therapeutic Efficacy in B-Cell Acute Lymphoblastic Leukemia

scientific article

Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity

scientific article

Cancer mucosa antigens as a novel immunotherapeutic class of tumor-associated antigen.

scientific article published on 26 September 2007

Chimeric Ad5.F35 vector evades anti-adenovirus serotype 5 neutralization opposing GUCY2C-targeted antitumor immunity

scientific article published on 01 August 2020

Chimeric adenoviral (Ad5.F35) and listeria vector prime-boost immunization is safe and effective for cancer immunotherapy

scientific article published in 2022

Companion vaccines for CAR T-cell therapy: applying basic immunology to enhance therapeutic efficacy

scientific article published on 29 June 2020

Comparative Evaluation of Veriflow® Listeria monocytogenes to USDA and AOAC Culture Based Methods for the Detection of Listeria monocytogenes in Food

scientific article published on September 2015

Could targeting T-helper cells aid the development of effective cancer vaccines?

article

Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens

scientific article published on December 2008

DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis

scientific article published on July 2015

Derivation and fluidity of acutely induced dysfunctional CD8+ T cells

scientific article published on 01 April 2008

Epithelial immunization induces polyfunctional CD8+ T cells and optimal mousepox protection

scientific article published on 4 June 2014

Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C.

scientific article

Functional macroautophagy induction by influenza A virus without a contribution to major histocompatibility complex class II-restricted presentation

scientific article

GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome

scientific article published on September 2017

GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress

scientific article published on 26 October 2017

GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity

scientific article (publication date: 2012)

GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity

scientific article published on 2 September 2016

GUCY2C-targeted cancer immunotherapy: past, present and future.

scientific article published on December 2011

Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer

scientific article published on 4 February 2017

Guanylyl Cyclase C Hormone Axis at the Intersection of Obesity and Colorectal Cancer

scientific article published on June 2016

Guanylyl cyclase C as a biomarker for targeted imaging and therapy of metastatic colorectal cancer

scientific article published on 01 February 2009

Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity

scientific article

Human GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases

article by Michael S Magee et al published May 2018 in Cancer immunology research

Immunotherapeutic strategies to target prognostic and predictive markers of cancer

scientific article published on February 2013

Immunotherapy regimens for metastatic colorectal carcinomas

scientific article

Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins

scientific article

Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer

scientific article published on October 2013

Is Financial Literacy Necessary for Radiation Oncology Residents?

scientific article published on 01 December 2014

Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease

scientific article

Mobilizing Toxins for Cancer Treatment: Historical Perspectives and Current Strategies

scientific article published on 23 June 2020

NHERF3 is necessary for Escherichia coli heat-stable enterotoxin-induced inhibition of NHE3: differences in signaling in mouse small intestine and Caco-2 cells

scientific article published on 31 July 2019

Non-thermal plasma induces immunogenic cell death in murine CT26 colorectal tumors

scholarly article by Abraham G. Lin et al published 2018 in OncoImmunology

Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis

scientific article published on January 2016

Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment

scientific article

Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope

scientific article published on 30 November 2016

Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High-Avidity Effector CD8+ T Cells

scientific article published on 24 March 2017

RB Loss Promotes Prostate Cancer Metastasis

scientific article published on 06 December 2016

ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice

scientific article published on 12 September 2017

Selective antigen-specific CD4(+) T-cell, but not CD8(+) T- or B-cell, tolerance corrupts cancer immunotherapy

scientific article

Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated, and MSI colorectal neoplasia

scientific article published on 02 February 2019

Silencing the intestinal GUCY2C tumor suppressor axis requires APC loss of heterozygosity

scientific article published on 28 June 2020

Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients

article

TCR Retrogenic Mice as a Model To Map Self-Tolerance Mechanisms to the Cancer Mucosa Antigen GUCY2C

Talkin' Toxins: From Coley's to Modern Cancer Immunotherapy

scientific article published on 09 April 2020

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

scientific article published on 16 March 2022

The Heat-Stable Enterotoxin Receptor, Guanylyl Cyclase C, as a Pharmacological Target in Colorectal Cancer Immunotherapy: A Bench-to-Bedside Current Report

scientific article published on 15 September 2017

The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.

scientific article

The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer

scientific article

The paracrine hormone hypothesis of colorectal cancer.

scientific article published on 8 August 2007

The swinging pendulum of cancer immunotherapy personalization

scientific article published on 05 May 2017

Therapeutic targeting of gastrointestinal cancer stem cells

scientific article published on 26 April 2019

Translating colorectal cancer prevention through the guanylyl cyclase C signaling axis

scientific article

Tumor radiation therapy creates therapeutic vaccine responses to the colorectal cancer antigen GUCY2C.

scientific article published on April 2014

as a Vector for Cancer Immunotherapy: Current Understanding and Progress

scholarly article by John C Flickinger et al published 25 July 2018 in Vaccines

siRNA-Encapsulated Hybrid Nanoparticles Target Mutant K-ras and Inhibit Metastatic Tumor Burden in a Mouse Model of Lung Cancer

scientific article published on 31 December 2016

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