List of works - Scheherazade Sadegh-Nasseri

A recombinant single-chain human class II MHC molecule (HLA-DR1) as a covalently linked heterotrimer of alpha chain, beta chain, and antigenic peptide, with immunogenicity in vitro and reduced affinity for bacterial superantigens.

scientific article published on August 1997

A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes.

scientific article

A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells

scientific article

Determinants of immunodominance for CD4 T cells

scientific article published on 08 January 2015

Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1.

scientific article published on January 2000

Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing

scientific article published on 19 April 2017

Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources

scientific article

Exogenous antigens bind MHC class II first, and are processed by cathepsins later

scientific article

HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes.

scientific article

HLA-DO and Its Role in MHC Class II Antigen Presentation.

scientific article published on 29 August 2013

HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation

scientific article

How MHC class II molecules work: peptide-dependent completion of protein folding.

scientific article published in February 1992

Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases

scientific article published on 18 February 2020

MHC Class II Auto-Antigen Presentation is Unconventional

scientific article (publication date: 2015)

Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo ⬇️

scientific article published on 05 June 2013

Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis

scientific article published on 04 October 2016

Resolution of infection promotes a state of dormancy and long survival of CD4 memory T cells.

scientific article published on March 2011

Selective reversal of H-2 linked genetic unresponsiveness to lysozymes. I. Non-H-2 gene(s) closely linked to the Ir-2 locus on chromosome 2 permit(s) an antilysozyme response in H-2b mice

scientific article published in January 1984

Short peptide sequences mimic HLA-DM functions.

scientific article published on 3 December 2007

Staphylococcal enterotoxin A induces small clusters of HLA-DR1 on B cells

scientific article (publication date: 2009)

Studying MHC class II peptide loading and editing in vitro

scientific article

Synaptic PDZ domain-mediated protein interactions are disrupted by inhalational anesthetics

scientific article

The convergent roles of tapasin and HLA-DM in antigen presentation.

scientific article

List of works by Scheherazade Sadegh-Nasseri

A recombinant single-chain human class II MHC molecule (HLA-DR1) as a covalently linked heterotrimer of alpha chain, beta chain, and antigenic peptide, with immunogenicity in vitro and reduced affinity for bacterial superantigens.

A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes.

A step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cells

Determinants of immunodominance for CD4 T cells

Determinants of the peptide-induced conformational change in the human class II major histocompatibility complex protein HLA-DR1.

Distorted Immunodominance by Linker Sequences or other Epitopes from a Second Protein Antigen During Antigen-Processing

Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources

Exogenous antigens bind MHC class II first, and are processed by cathepsins later

HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes.

HLA-DO and Its Role in MHC Class II Antigen Presentation.

HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation

How MHC class II molecules work: peptide-dependent completion of protein folding.

Lack of the MHC class II chaperone H2-O causes susceptibility to autoimmune diseases

MHC Class II Auto-Antigen Presentation is Unconventional

Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo ⬇️

Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis

Resolution of infection promotes a state of dormancy and long survival of CD4 memory T cells.

Selective reversal of H-2 linked genetic unresponsiveness to lysozymes. I. Non-H-2 gene(s) closely linked to the Ir-2 locus on chromosome 2 permit(s) an antilysozyme response in H-2b mice

Short peptide sequences mimic HLA-DM functions.

Staphylococcal enterotoxin A induces small clusters of HLA-DR1 on B cells

Studying MHC class II peptide loading and editing in vitro

Synaptic PDZ domain-mediated protein interactions are disrupted by inhalational anesthetics

The convergent roles of tapasin and HLA-DM in antigen presentation.