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List of works by Bernd Meibohm

A Modern View of Excipient Effects on Bioequivalence: Case Study of Sorbitol

scientific article published on 18 October 2006

A New Combination of a Pleuromutilin Derivative and Doxycycline for Treatment of Multidrug-Resistant Acinetobacter baumannii

scientific article

A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents

scientific article published on 07 August 2008

A pharmacokinetic/pharmacodynamic approach to predict the cumulative cortisol suppression of inhaled corticosteroids

scientific article published in April 1999

A simple in vitro PK/PD model system to determine time-kill curves of drugs against Mycobacteria

scientific article published on 11 September 2009

A tandem mass spectrometry assay for the simultaneous determination of acetaminophen, caffeine, phenytoin, ranitidine, and theophylline in small volume pediatric plasma specimens

scientific article

ADME for Therapeutic Biologics: Antibody-Derived Proteins and Proteins with Novel Scaffolds

Alterations in cellular pharmacokinetics and pharmacodynamics of elvitegravir in response to ethanol exposure in HIV-1 infected monocytic (U1) cells

scientific article

American Association of Pharmaceutical Scientists National Biotechnology Conference Short Course: Translational Challenges in Developing Antibody-Drug Conjugates: May 24, 2012, San Diego, CA.

scientific article published on 19 December 2012

Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections

scientific article

Antitubercular nitrofuran isoxazolines with improved pharmacokinetic properties

scientific article published on 28 August 2012

Applications of pharmacometrics in the clinical development and pharmacotherapy of anti-infectives

scientific article published on March 2013

Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans.

scientific article published in September 2017

Biopharmaceutics, pharmacokinetics and pharmacodynamics of antituberculosis drugs

scientific article published on January 2008

Carvedilol therapy in pediatric patients with congestive heart failure: a study investigating clinical and pharmacokinetic parameters.

scientific article published in May 2002

Challenges and Opportunities for Increasing the Knowledge Base Related to Drug Biotransformation and Pharmacokinetics during Growth and Development.

scientific article published on July 2016

Challenges and considerations for development of therapeutic proteins in pediatric patients.

scientific article

Clinical pharmacology of bispecific antibody constructs.

scientific article

Cognitive Impairment and Medication Complexity in Community-Living Older Adults: The Health, Aging and Body Composition Study.

scientific article published on July 2012

Comparative performance of cell life span and cell transit models for describing erythropoietic drug effects

scientific article published on 18 October 2011

Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice

scientific article published on 31 December 2018

Comparison of caffeine disposition following administration by oral solution (energy drink) and inspired powder (AeroShot) in human subjects.

scientific article

Core Entrustable Professional Activities in Clinical Pharmacology for Entering Residency: Biologics

scientific article published on 14 June 2017

Core Entrustable Professional Activities in Clinical Pharmacology for Entering Residency: Common Problem Drugs and How to Prescribe Them

scientific article published on 15 February 2019

Cross-Linked Polyphenol-Based Drug Nano-Self-Assemblies Engineered to Blockade Prostate Cancer Senescence

scientific article published on 08 October 2019

Dependency of Cortisol Suppression on the Administration Time of Inhaled Corticosteroids

scientific article published on 01 August 1997

Developing a gene expression model for predicting ventilator-associated pneumonia in trauma patients: a pilot study

scientific article

Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599

scientific article published on 18 July 2019

Development of a safe and effective pediatric dosing regimen for sotalol based on population pharmacokinetics and pharmacodynamics in children with supraventricular tachycardia

scientific article

Discovery of novel isoxazolines as anti-tuberculosis agents

scientific article

Drug Development of Therapeutic Monoclonal Antibodies.

scientific article published on 24 June 2016

Dynamic Modeling of Cortisol Reduction after Inhaled Administration of Fluticasone Propionate

article

Dynamic time-kill curve characterization of spectinamide antibiotics 1445 and 1599 for the treatment of tuberculosis

scientific article published on 09 November 2018

Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS/MS Method

scientific article

Effects of alcohol on human carboxylesterase drug metabolism

scientific article published on June 2015

Essential criteria for pharmacokinetic studies supporting bioequivalence of inhaled tiotropium bromide products

scientific article published on 02 June 2015

Ethanol lock therapy: a pilot infusion study in infants

scientific article published on 28 January 2015

Evaluation of vancomycin dosing regimens in preterm and term neonates using Monte Carlo simulations

scientific article published on 9 April 2012

Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver

scientific article published on 20 April 2016

From the bench to clinical practice: understanding the challenges and uncertainties in immunogenicity testing for biopharmaceuticals.

scientific article

G2677T and C3435T Genotype and Haplotype Are Associated With HepaticABCB1(MDR1) Expression

scientific article published on 01 March 2006

Genetic ancestry in lung-function predictions

scientific article

Genetic ancestry-smoking interactions and lung function in African Americans: a cohort study

scientific article (publication date: 2012)

Genetic variation in antioxidant enzymes and lung function

scientific article

Genetic variation in antioxidant enzymes, cigarette smoking, and longitudinal change in lung function

scientific article

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

scientific article

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

scientific article

Immune Suppression During Preclinical Drug Development Mitigates Immunogenicity-Mediated Impact on Therapeutic Exposure

scientific article published on 9 January 2017

Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy ⬇️

scientific article published on March 10, 2012

In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis Antibiotics

scientific article

In vitro pharmacokinetic/pharmacodynamic models in anti-infective drug development: focus on TB

scientific article

Influence of Ethanol on Darunavir Hepatic Clearance and Intracellular PK/PD in HIV-Infected Monocytes, and CYP3A4-Darunavir Interactions Using Inhibition and in Silico Binding Studies

scientific article published on 14 June 2017

Is age-related decline in lean mass and physical function accelerated by obstructive lung disease or smoking?

scientific article

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

scientific article

Long Pulmonary Residence Time and Plasma Half-Life of Tiotropium: Implications for Pharmacokinetic Bioequivalence Studies

scientific article published in June 2017

Model-Based Exposure-Response Assessment for Spectinamide 1810 in a Mouse Model of Tuberculosis

scientific article published on 23 August 2021

Modulation of metoprolol pharmacokinetics and hemodynamics by diphenhydramine coadministration during exercise testing in healthy premenopausal women

scientific article

Novel endogenous glycan therapy for retinal diseases: safety, in vitro stability, ocular pharmacokinetic modeling, and biodistribution.

scientific article published on 28 January 2014

PREDICTORS OF MORTALITY IN ELDERLY SUBJECTS WITH OBSTRUCTIVE AIRWAY DISEASE: THE PILE SCORE

scientific article published in October 2006

Pattern Recognition in Pharmacokinetic Data Analysis

scientific article

Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis

scientific article (publication date: 2014)

Pharmacokinetic and pharmacodynamic evaluation of fluticasone propionate after inhaled administration.

scientific article published in February 1998

Pharmacokinetic/Pharmacodynamic Evaluation of Systemic Effects of Flunisolide after Inhalation

scientific article published on 01 October 1997

Pharmacokinetic/Pharmacodynamic Studies in Drug Product Development ⬇️

scientific article published on January 1, 2002

Pharmacokinetically-guided lead optimization of nitrofuranylamide anti-tuberculosis agents

scientific article published on 14 March 2008

Pharmacokinetics and Clinical Pharmacology of Monoclonal Antibodies in Pediatric Patients

scientific article published on 01 April 2020

Pharmacokinetics and pharmacodynamics of inhaled corticosteroids ⬇️

scientific article published on April 1, 1998

Pharmacokinetics and pharmacokinetic-pharmacodynamic correlations of therapeutic peptides.

scientific article published on October 2013

Pharmacokinetics of Monoclonal Antibodies.

scientific article published on 27 June 2017

Pharmacokinetics of a combination of Δ9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock

scientific article published on 23 December 2010

Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers

scientific article published on 12 August 2008

Pharmacokinetics of intravenous amiodarone in children.

scientific article published on 19 September 2013

Pharmacokinetics of ponazuril after oral administration to healthy llamas (Lama glama)

scientific article published on 01 October 2011

Pharmacometric Applications and Challenges in the Development of Therapeutic Antibodies in Immuno-Oncology

article

Pharmacometrics as a discipline is entering the "industrialization" phase: standards, automation, knowledge sharing, and training are critical for future success.

scientific article

Phase II Metabolic Pathways of Spectinamide Antitubercular Agents: A Comparative Study of the Reactivity of 4-Substituted Pyridines to Glutathione Conjugation

scientific article published on 7 September 2015

Physiologically based pharmacokinetic (PBPK) modeling in children

scientific article published on 06 June 2012

Physiologically-Based Pharmacokinetic (PBPK) Modeling Providing Insights into Fentanyl Pharmacokinetics in Adults and Pediatric Patients

scientific article published on 23 September 2020

Population Pharmacokinetic/Pharmacodynamic Analyses as the Basis for Dosing of Therapeutic Monoclonal Antibodies

scientific article published on 01 December 2011

Population Pharmacokinetics of Therapeutic Monoclonal Antibodies

scientific article published on October 1, 2010

Population pharmacokinetic meta-analysis of individual data to design the first randomized efficacy trial of vancomycin in neonates and young infants

scientific article published on 01 August 2019

Population pharmacokinetics and dose simulation of carvedilol in paediatric patients with congestive heart failure.

scientific article published on 8 November 2007

Population pharmacokinetics of cetuximab in patients with squamous cell carcinoma of the head and neck

scientific article published on 24 January 2008

Preclinical evaluation of SMM-189, a cannabinoid receptor 2-specific inverse agonist.

scientific article published on 6 July 2015

Predictors of mortality in elderly subjects with obstructive airway disease: the PILE score

scientific article

Primary Lung Dendritic Cell Cultures to Assess Efficacy of Spectinamide-1599 Against Intracellular

article

Protein engineering for improved pharmacologic characteristics of established monoclonal antibody-based therapeutics

scientific article published in October 2014

Real-time PCR-based genotyping assay for CXCR2 polymorphisms

scientific article published in March 2004

Regulatory and Ethical Issues in Pediatric Clinical Research: Recommendations From a Panel Discussion

scientific article published on 17 May 2017

Response to "Physiologically based pharmacokinetic modeling at the extremes of age".

scientific article published on 28 November 2012

SYBR Green-based real-time PCR allelic discrimination assay for beta2-adrenergic receptor polymorphisms

scientific article published in September 2005

Simple and sensitive assay for quantification of oseltamivir and its active metabolite oseltamivir carboxylate in human plasma using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry: improved appli

scientific article

Single- and multiple-dose pharmacokinetics of pioglitazone in adolescents with type 2 diabetes

scientific article published in October 2005

Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux

scientific article published on 26 January 2014

Sterilization of Mycobacterium tuberculosis infected samples using methanol preserves anti-tuberculosis drugs for subsequent pharmacological testing studies

scientific article published on 06 June 2019

Strategic Biomarkers for Drug Development in Treating Rare Diseases and Diseases in Neonates and Infants ⬇️

scientific article published on January 19, 2013

Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions

scientific article published on 11 November 2016

Study design and simulation approach

scientific article published in January 2011

Sustained plasma hepcidin suppression and iron elevation by Anticalin-derived hepcidin antagonist in cynomolgus monkey.

scientific article published on 12 January 2018

Tannic acid-inspired paclitaxel nanoparticles for enhanced anticancer effects in breast cancer cells

Termination of automatic atrial tachycardia in an infant by adequate sotalol dosing. Indication of clinically relevant age-dependent pharmacokinetics of sotalol

scientific article published in May 2001

The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360

scientific article published on 03 November 2018

The Journey to AAPS 2020: a Reflection from Strategic Planning to PharmSci 360

article

The clinical pharmacokinetics of phosphodiesterase-5 inhibitors for erectile dysfunction.

scientific article

The current role of model-based drug development.

scientific article published on April 2010

The in silico child: using simulation to guide pediatric drug development and manage pediatric pharmacotherapy.

scientific article published on 16 June 2009

The influence of abdominal visceral fat on inflammatory pathways and mortality risk in obstructive lung disease

scientific article

The role of pharmacokinetics and pharmacodynamics in phosphodiesterase-5 inhibitor therapy.

scientific article published on 21 September 2006

Tissue Penetration of a Novel Spectinamide Antibiotic for the Treatment of Tuberculosis

scientific article published on 16 March 2016

Tools for predicting the PK/PD of therapeutic proteins

scientific article published on 04 May 2015

Translational Biomarkers: from Preclinical to Clinical a Report of 2009 AAPS/ACCP Biomarker Workshop ⬇️

scientific article published on March 30, 2011

Translational PK/PD of anti-infective therapeutics.

scientific article published on September 2016

Urinary metabolites from mango (Mangifera indicaL. cv. Keitt) galloyl derivatives and in vitro hydrolysis of gallotannins in physiological conditions

scientific article published on 02 February 2016

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