List of works - Stefan Schillberg

'Molecular farming' of antibodies in plants

scientific article published on 18 February 2003

A Plant-Based Transient Expression System for the Rapid Production of Malaria Vaccine Candidates

scientific article published in January 2016

A downstream process allowing the efficient isolation of a recombinant amphiphilic protein from tobacco leaves

scientific article published on 16 April 2014

A membrane-bound matrix-metalloproteinase from Nicotiana tabacum cv. BY-2 is induced by bacterial pathogens

scientific article

A monoclonal antibody that specifically binds chitosan in vitro and in situ on fungal cell walls.

scientific article published in August 2010

A potential nanobiotechnology platform based on infectious bursal disease subviral particles.

scientific article published on 9 January 2012

A versatile coupled cell-free transcription-translation system based on tobacco BY-2 cell lysates

scientific article published on 16 January 2015

Abscisic acid and the herbicide safener cyprosulfamide cooperatively enhance abiotic stress tolerance in rice

Affinity purification of a framework 1 engineered mouse/human chimeric IgA2 antibody from tobacco.

scientific article published on 19 July 2011

An assay for the detection of grapevine leafroll-associated virus 3 using a single-chain fragment variable antibody

scientific article published on 11 December 2008

An immunohistochemical assay on human tissue using a human primary antibody

scientific article published in January 2014

Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate--Tackling the Cocktail Challenge

scientific article published on 6 July 2015

Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail

scientific article published on 17 May 2016

Antibody-Mediated Pathogen Resistance in Plants.

scientific article published in January 2016

Antibody-based metabolic engineering in plants.

scientific article

Antibody-mediated resistance against plant pathogens ⬇️

scientific article published on August 19, 2011

Apoplastic and cytosolic expression of full-size antibodies and antibody fragments in Nicotiana tabacum

scientific article

Application of a Scalable Plant Transient Gene Expression Platform for Malaria Vaccine Development

scientific article

Aspergillus-specific antibodies - Targets and applications

scientific article published on 30 March 2018

Assessment of cultivation factors that affect biomass and geraniol production in transgenic tobacco cell suspension cultures

scientific article

Biochemical properties of the matrix metalloproteinase NtMMP1 from Nicotiana tabacum cv. BY-2 suspension cells

scientific article

Commercial aspects of pharmaceutical protein production in plants

scientific article published in January 2013

Comparative evaluation of heterologous production systems for recombinant pulmonary surfactant protein D.

scientific article

Comprehensive characterization of two different Nicotiana tabacum cell lines leads to doubled GFP and HA protein production by media optimization

scientific article

Correlation between mass transfer coefficient kLa and relevant operating parameters in cylindrical disposable shaken bioreactors on a bench-to-pilot scale.

scientific article published on 2 December 2013

Detailed functional characterization of glycosylated and nonglycosylated variants of malaria vaccine candidate PfAMA1 produced in Nicotiana benthamiana and analysis of growth inhibitory responses in rabbits

scientific article published on 18 September 2014

Development of an optimized tetracycline-inducible expression system to increase the accumulation of interleukin-10 in tobacco BY-2 suspension cells

scientific article

Developments in the production of mucosal antibodies in plants.

scientific article

Evaluation of tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots for the production of geraniol, the first committed step in terpenoid indole alkaloid pathway

scientific article published on 14 February 2014

Expression and characterization of bispecific single-chain Fv fragments produced in transgenic plants

scientific article published on 01 June 1999

GMP issues for recombinant plant-derived pharmaceutical proteins.

scientific article published on 12 August 2011

GST fusion proteins cause false positives during selection of viral movement protein specific single chain antibodies.

scientific article

Generation and characterization of a recombinant antibody fragment that binds to the coat protein of grapevine leafroll-associated virus 3.

scientific article

Generation and expression in plants of a single-chain variable fragment antibody against the immunodominant membrane protein of Candidatus phytoplasma aurantifolia.

scientific article

Genome Editing in Agriculture: Technical and Practical Considerations

scientific article published on 13 June 2019

Genome editing: intellectual property and product development in plant biotechnology

scientific article published on 4 May 2016

Grapevine fanleaf virus (GFLV)-specific antibodies confer GFLV and Arabis mosaic virus (ArMV) resistance in Nicotiana benthamiana.

scientific article

Heat-precipitation allows the efficient purification of a functional plant-derived malaria transmission-blocking vaccine candidate fusion protein

scientific article published on 13 March 2015

High-value products from plants: the challenges of process optimization.

scientific article published on 03 January 2015

Immunomodulation of polyamine biosynthesis in tobacco plants has a significant impact on polyamine levels and generates a dwarf phenotype

article

Improved fluoroquinolone detection in ELISA through engineering of a broad-specific single-chain variable fragment binding simultaneously to 20 fluoroquinolones.

scientific article

Infrared picosecond laser for perforation of single plant cells

scientific article

Inhibition of protease activity by antisense RNA improves recombinant protein production in Nicotiana tabacum cv. Bright Yellow 2 (BY-2) suspension cells

scientific article published on 23 June 2014

Malaria vaccine candidate antigen targeting the pre-erythrocytic stage of Plasmodium falciparum produced at high level in plants

scientific article published on 10 October 2014

Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants

scientific article

Molecular farming in plants: host systems and expression technology

scientific article

Molecular farming in tobacco hairy roots by triggering the secretion of a pharmaceutical antibody.

scientific article

Molecular farming of human tissue transglutaminase in tobacco plants

scientific article published on 02 July 2008

Molecular farming of pharmaceutical proteins using plant suspension cell and tissue cultures

scientific article published on January 2013

Molecular farming of recombinant antibodies in plants

scientific article published on 01 March 2003

Monoclonal tobacco cell lines with enhanced recombinant protein yields can be generated from heterogeneous cell suspension cultures by flow sorting

scientific article

More for less: Improving the biomass yield of a pear cell suspension culture by design of experiments

scientific article published on 18 March 2016

Next-generation sequencing is a robust strategy for the high-throughput detection of zygosity in transgenic maize.

scientific article published on 4 February 2015

Opportunities for recombinant antigen and antibody expression in transgenic plants--technology assessment.

scientific article

Optimization of a multi-stage, multi-subunit malaria vaccine candidate for the production in Pichia pastoris by the identification and removal of protease cleavage sites

scientific article

Optimizing expression of a rare codon-rich viral protein in Escherichia coli using the IMPACT system

scientific article published in July 1999

Optimizing the yield of recombinant pharmaceutical proteins in plants.

scientific article published on January 2013

Patterns of CRISPR/Cas9 activity in plants, animals and microbes

scientific article

Pharmaceuticals

Plant Cell-Based Recombinant Antibody Manufacturing with a 200 L Orbitally Shaken Disposable Bioreactor

scientific article published in January 2016

Plant expression and characterization of the transmission-blocking vaccine candidate PfGAP50.

scientific article published in December 2015

Plant-based production of biopharmaceuticals

scientific article published on April 2004

Plant-based production of recombinant Plasmodium surface protein pf38 and evaluation of its potential as a vaccine candidate

scientific article

Plant-derived chimeric antibodies inhibit the invasion of human fibroblasts by

article

Production of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAalpha1) in tobacco is hampered by proteolysis

scientific article

Production of an active recombinant thrombomodulin derivative in transgenic tobacco plants and suspension cells

scientific article published in June 2005

Production of antibodies in plants and their use for global health.

scientific article

Protective oral vaccination against infectious bursal disease virus using the major viral antigenic protein VP2 produced in Pichia pastoris

scientific article

Recombinant human tissue transglutaminase produced into tobacco suspension cell cultures is active and recognizes autoantibodies in the serum of coeliac patients.

scientific article published in April 2005

Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor

scientific article published on 13 October 2014

Simple and portable magnetic immunoassay for rapid detection and sensitive quantification of plant viruses

scientific article published on 20 February 2015

Simultaneous treatment with tebuconazole and abscisic acid induces drought and salinity stress tolerance in Arabidopsis thaliana by maintaining key plastid protein levels

scientific article published on 5 February 2013

Statistical experimental designs for the production of secondary metabolites in plant cell suspension cultures

scientific article published on 13 September 2016

Tackling Unwanted Proteolysis in Plant Production Hosts Used for Molecular Farming

scientific article published in 2016

Targeted gene exchange in plant cells mediated by a zinc finger nuclease double cut.

scientific article published in October 2015

Targeting tryptophan decarboxylase to selected subcellular compartments of tobacco plants affects enzyme stability and in vivo function and leads to a lesion-mimic phenotype.

scientific article

Thanatin confers partial resistance against aflatoxigenic fungi in maize (Zea mays).

scientific article published on 13 June 2015

The expression of a recombinant glycolate dehydrogenase polyprotein in potato (Solanum tuberosum) plastids strongly enhances photosynthesis and tuber yield

scientific article published on 7 March 2014

The production of recombinant cationic α-helical antimicrobial peptides in plant cells induces the formation of protein bodies derived from the endoplasmic reticulum.

scientific article published on 17 September 2013

The stage-specific in vitro efficacy of a malaria antigen cocktail provides valuable insights into the development of effective multi-stage vaccines

scientific article published on 24 April 2015

Tobacco BY-2 cell-free lysate: an alternative and highly-productive plant-based in vitro translation system

scientific article

Transgenic plants in the biopharmaceutical market.

scientific article

Transient expression of a tumor-specific single-chain fragment and a chimeric antibody in tobacco leaves

scientific article published on September 1999

Transient transformation of the rust fungus Puccinia graminis f. sp. tritici

scientific article published on 01 January 2000

Viral and murine interleukin-10 are correctly processed and retain their biological activity when produced in tobacco

scientific article

Yeast surface display is a novel tool for the rapid immunological characterization of plant-derived food allergens

scientific article published in March 2015

List of works by Stefan Schillberg

'Molecular farming' of antibodies in plants

A Plant-Based Transient Expression System for the Rapid Production of Malaria Vaccine Candidates

A downstream process allowing the efficient isolation of a recombinant amphiphilic protein from tobacco leaves

A membrane-bound matrix-metalloproteinase from Nicotiana tabacum cv. BY-2 is induced by bacterial pathogens

A monoclonal antibody that specifically binds chitosan in vitro and in situ on fungal cell walls.

A potential nanobiotechnology platform based on infectious bursal disease subviral particles.

A versatile coupled cell-free transcription-translation system based on tobacco BY-2 cell lysates

Abscisic acid and the herbicide safener cyprosulfamide cooperatively enhance abiotic stress tolerance in rice

Affinity purification of a framework 1 engineered mouse/human chimeric IgA2 antibody from tobacco.

An assay for the detection of grapevine leafroll-associated virus 3 using a single-chain fragment variable antibody

An immunohistochemical assay on human tissue using a human primary antibody

Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate--Tackling the Cocktail Challenge

Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail

Antibody-Mediated Pathogen Resistance in Plants.

Antibody-based metabolic engineering in plants.

Antibody-mediated resistance against plant pathogens ⬇️

Apoplastic and cytosolic expression of full-size antibodies and antibody fragments in Nicotiana tabacum

Application of a Scalable Plant Transient Gene Expression Platform for Malaria Vaccine Development

Aspergillus-specific antibodies - Targets and applications

Assessment of cultivation factors that affect biomass and geraniol production in transgenic tobacco cell suspension cultures

Biochemical properties of the matrix metalloproteinase NtMMP1 from Nicotiana tabacum cv. BY-2 suspension cells

Commercial aspects of pharmaceutical protein production in plants

Comparative evaluation of heterologous production systems for recombinant pulmonary surfactant protein D.

Comprehensive characterization of two different Nicotiana tabacum cell lines leads to doubled GFP and HA protein production by media optimization

Correlation between mass transfer coefficient kLa and relevant operating parameters in cylindrical disposable shaken bioreactors on a bench-to-pilot scale.

Detailed functional characterization of glycosylated and nonglycosylated variants of malaria vaccine candidate PfAMA1 produced in Nicotiana benthamiana and analysis of growth inhibitory responses in rabbits

Development of an optimized tetracycline-inducible expression system to increase the accumulation of interleukin-10 in tobacco BY-2 suspension cells

Developments in the production of mucosal antibodies in plants.

Evaluation of tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots for the production of geraniol, the first committed step in terpenoid indole alkaloid pathway

Expression and characterization of bispecific single-chain Fv fragments produced in transgenic plants

GMP issues for recombinant plant-derived pharmaceutical proteins.

GST fusion proteins cause false positives during selection of viral movement protein specific single chain antibodies.

Generation and characterization of a recombinant antibody fragment that binds to the coat protein of grapevine leafroll-associated virus 3.

Generation and expression in plants of a single-chain variable fragment antibody against the immunodominant membrane protein of Candidatus phytoplasma aurantifolia.

Genome Editing in Agriculture: Technical and Practical Considerations

Genome editing: intellectual property and product development in plant biotechnology

Grapevine fanleaf virus (GFLV)-specific antibodies confer GFLV and Arabis mosaic virus (ArMV) resistance in Nicotiana benthamiana.

Heat-precipitation allows the efficient purification of a functional plant-derived malaria transmission-blocking vaccine candidate fusion protein

High-value products from plants: the challenges of process optimization.

Immunomodulation of polyamine biosynthesis in tobacco plants has a significant impact on polyamine levels and generates a dwarf phenotype

Improved fluoroquinolone detection in ELISA through engineering of a broad-specific single-chain variable fragment binding simultaneously to 20 fluoroquinolones.

Infrared picosecond laser for perforation of single plant cells

Inhibition of protease activity by antisense RNA improves recombinant protein production in Nicotiana tabacum cv. Bright Yellow 2 (BY-2) suspension cells

Malaria vaccine candidate antigen targeting the pre-erythrocytic stage of Plasmodium falciparum produced at high level in plants

Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants

Molecular farming in plants: host systems and expression technology

Molecular farming in tobacco hairy roots by triggering the secretion of a pharmaceutical antibody.

Molecular farming of human tissue transglutaminase in tobacco plants

Molecular farming of pharmaceutical proteins using plant suspension cell and tissue cultures

Molecular farming of recombinant antibodies in plants

Monoclonal tobacco cell lines with enhanced recombinant protein yields can be generated from heterogeneous cell suspension cultures by flow sorting

More for less: Improving the biomass yield of a pear cell suspension culture by design of experiments

Next-generation sequencing is a robust strategy for the high-throughput detection of zygosity in transgenic maize.

Opportunities for recombinant antigen and antibody expression in transgenic plants--technology assessment.

Optimization of a multi-stage, multi-subunit malaria vaccine candidate for the production in Pichia pastoris by the identification and removal of protease cleavage sites

Optimizing expression of a rare codon-rich viral protein in Escherichia coli using the IMPACT system

Optimizing the yield of recombinant pharmaceutical proteins in plants.

Patterns of CRISPR/Cas9 activity in plants, animals and microbes

Pharmaceuticals

Plant Cell-Based Recombinant Antibody Manufacturing with a 200 L Orbitally Shaken Disposable Bioreactor

Plant expression and characterization of the transmission-blocking vaccine candidate PfGAP50.

Plant-based production of biopharmaceuticals

Plant-based production of recombinant Plasmodium surface protein pf38 and evaluation of its potential as a vaccine candidate

Plant-derived chimeric antibodies inhibit the invasion of human fibroblasts by

Production of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAalpha1) in tobacco is hampered by proteolysis

Production of an active recombinant thrombomodulin derivative in transgenic tobacco plants and suspension cells

Production of antibodies in plants and their use for global health.

Protective oral vaccination against infectious bursal disease virus using the major viral antigenic protein VP2 produced in Pichia pastoris

Recombinant human tissue transglutaminase produced into tobacco suspension cell cultures is active and recognizes autoantibodies in the serum of coeliac patients.

Scaled-up manufacturing of recombinant antibodies produced by plant cells in a 200-L orbitally-shaken disposable bioreactor

Simple and portable magnetic immunoassay for rapid detection and sensitive quantification of plant viruses

Simultaneous treatment with tebuconazole and abscisic acid induces drought and salinity stress tolerance in Arabidopsis thaliana by maintaining key plastid protein levels

Statistical experimental designs for the production of secondary metabolites in plant cell suspension cultures

Tackling Unwanted Proteolysis in Plant Production Hosts Used for Molecular Farming

Targeted gene exchange in plant cells mediated by a zinc finger nuclease double cut.

Targeting tryptophan decarboxylase to selected subcellular compartments of tobacco plants affects enzyme stability and in vivo function and leads to a lesion-mimic phenotype.

Thanatin confers partial resistance against aflatoxigenic fungi in maize (Zea mays).

The expression of a recombinant glycolate dehydrogenase polyprotein in potato (Solanum tuberosum) plastids strongly enhances photosynthesis and tuber yield

The production of recombinant cationic α-helical antimicrobial peptides in plant cells induces the formation of protein bodies derived from the endoplasmic reticulum.