List of works - Qingyu Wu

A c.464T>A mutation in VHL gene in a Chinese family with VHL syndrome ⬇️

scientific article published on December 1, 2012

A conserved LDL-receptor motif regulates corin and CD320 membrane targeting in polarized renal epithelial cells

scientific article published on 02 November 2020

A corin variant identified in hypertensive patients that alters cytoplasmic tail and reduces cell surface expression and activity

scientific article

A novel cytoplasmic tail motif regulates mouse corin expression on the cell surface.

scientific article

ANP-induced signaling cascade and its implications in renal pathophysiology

scientific article published on 28 January 2015

An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss

scientific article

Atrial natriuretic peptide in cardiovascular biology and disease (NPPA)

scientific article

Autoactivation and calpain-1-mediated shedding of hepsin in human hepatoma cells

scientific article published on 28 August 2019

Corin Deficiency Alters Adipose Tissue Phenotype and Impairs Thermogenesis in Mice

scientific article published in 2022

Corin Mutation R539C from Hypertensive Patients Impairs Zymogen Activation and Generates an Inactive Alternative Ectodomain Fragment ⬇️

scientific article published on January 31, 2013

Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension

scientific article published on 10 October 2005

Corin in natriuretic peptide processing and hypertension

scientific article

Corin: a serine protease

scientific article published on 01 January 2011

Corin: new insights into the natriuretic peptide system

scientific article

Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases

scientific journal article

Detection of autoantibodies against platelet glycoproteins in patients with immune thrombocytopenic purpura by flow cytometric immunobead array ⬇️

scientific article published on October 25, 2012

Distinct roles of N-glycosylation at different sites of corin in cell membrane targeting and ectodomain shedding.

scientific article

Ectopic expression of human airway trypsin-like protease 4 in acute myeloid leukemia promotes cancer cell invasion and tumor growth

scientific article published on 07 March 2019

Effect of sialylated O-glycans in pro-brain natriuretic peptide stability.

scientific article published on 26 March 2010

Effects of anticoagulants on human plasma soluble corin levels measured by ELISA.

scientific article

Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease ⬇️

scientific article published on January 15, 1998

Glycosylation and processing of pro-B-type natriuretic peptide in cardiomyocytes.

scientific article

Hepsin enhances liver metabolism and inhibits adipocyte browning in mice

scientific article published on 13 May 2020

Hepsin: a multifunctional transmembrane serine protease in pathobiology

scientific article published on 09 December 2020

Human corin isoforms with different cytoplasmic tails that alter cell surface targeting

scientific article

Identification and functional analysis of CORIN variants in hypertensive patients.

scientific article

Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice ⬇️

scientific article published on March 14, 2012

Intracellular autoactivation of TMPRSS11A, an airway epithelial transmembrane serine protease

scientific article published on 15 July 2020

Iron-refractory iron deficiency anemia: new molecular mechanisms.

scientific article published on 23 September 2009

Krüppel-like factor 17 upregulates uterine corin expression and promotes spiral artery remodeling in pregnancy

scientific article published on 27 July 2020

Ligand specificity of human thrombomodulin. Equilibrium binding of human thrombin, meizothrombin, and factor Xa to recombinant thrombomodulin ⬇️

scientific article published on 01 April 1992

Localization of corin and atrial natriuretic peptide expression in human renal segments.

scientific article published on 24 June 2016

Localization of the single-stranded DNA binding site in the thrombin anion-binding exosite ⬇️

scientific article published on December 5, 1992

Membrane-anchored serine proteases in health and disease.

scientific article published on January 2011

Molecular forms of natriuretic peptides in heart failure and their implications.

scientific article published on 17 May 2009

N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding.

scientific article

N-glycosylation is required for matriptase-2 autoactivation and ectodomain shedding

scientific article

PCSK6-mediated corin activation is essential for normal blood pressure

scientific article

Plasma soluble corin in patients with heart failure.

scientific article

Reduced serum corin levels in patients with osteoporosis.

scientific article published on 18 September 2013

Reduced urinary corin levels in patients with chronic kidney disease.

scientific article

Role of corin and atrial natriuretic peptide in preeclampsia

scientific article

Role of corin in the regulation of blood pressure

scientific article published on 24 November 2016

Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy

scientific article

Role of glycosylation in corin zymogen activation.

scientific article

Salt-sensitive hypertension and cardiac hypertrophy in transgenic mice expressing a corin variant identified in blacks

scientific article

Serine proteases and cardiac function.

scientific article

The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss.

scientific article published on 24 March 2017

The serine protease corin in cardiovascular biology and disease

scientific article

Type II transmembrane serine proteases

scientific article published on 01 June 2009

Upregulation of corin gene expression in hypertrophic cardiomyocytes and failing myocardium

scientific article

List of works by Qingyu Wu

A c.464T&gt;A mutation in VHL gene in a Chinese family with VHL syndrome ⬇️

A conserved LDL-receptor motif regulates corin and CD320 membrane targeting in polarized renal epithelial cells

A corin variant identified in hypertensive patients that alters cytoplasmic tail and reduces cell surface expression and activity

A novel cytoplasmic tail motif regulates mouse corin expression on the cell surface.

ANP-induced signaling cascade and its implications in renal pathophysiology

An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss

Atrial natriuretic peptide in cardiovascular biology and disease (NPPA)

Autoactivation and calpain-1-mediated shedding of hepsin in human hepatoma cells

Corin Deficiency Alters Adipose Tissue Phenotype and Impairs Thermogenesis in Mice

Corin Mutation R539C from Hypertensive Patients Impairs Zymogen Activation and Generates an Inactive Alternative Ectodomain Fragment ⬇️

Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension

Corin in natriuretic peptide processing and hypertension

Corin: a serine protease

Corin: new insights into the natriuretic peptide system

Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases

Detection of autoantibodies against platelet glycoproteins in patients with immune thrombocytopenic purpura by flow cytometric immunobead array ⬇️

Distinct roles of N-glycosylation at different sites of corin in cell membrane targeting and ectodomain shedding.

Ectopic expression of human airway trypsin-like protease 4 in acute myeloid leukemia promotes cancer cell invasion and tumor growth

Effect of sialylated O-glycans in pro-brain natriuretic peptide stability.

Effects of anticoagulants on human plasma soluble corin levels measured by ELISA.

Generation and characterization of mice deficient in hepsin, a hepatic transmembrane serine protease ⬇️

Glycosylation and processing of pro-B-type natriuretic peptide in cardiomyocytes.

Hepsin enhances liver metabolism and inhibits adipocyte browning in mice

Hepsin: a multifunctional transmembrane serine protease in pathobiology

Human corin isoforms with different cytoplasmic tails that alter cell surface targeting

Identification and functional analysis of CORIN variants in hypertensive patients.

Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice ⬇️

Intracellular autoactivation of TMPRSS11A, an airway epithelial transmembrane serine protease

Iron-refractory iron deficiency anemia: new molecular mechanisms.

Krüppel-like factor 17 upregulates uterine corin expression and promotes spiral artery remodeling in pregnancy

Ligand specificity of human thrombomodulin. Equilibrium binding of human thrombin, meizothrombin, and factor Xa to recombinant thrombomodulin ⬇️

Localization of corin and atrial natriuretic peptide expression in human renal segments.

Localization of the single-stranded DNA binding site in the thrombin anion-binding exosite ⬇️

Membrane-anchored serine proteases in health and disease.

Molecular forms of natriuretic peptides in heart failure and their implications.

N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding.

N-glycosylation is required for matriptase-2 autoactivation and ectodomain shedding

PCSK6-mediated corin activation is essential for normal blood pressure

Plasma soluble corin in patients with heart failure.

Reduced serum corin levels in patients with osteoporosis.

Reduced urinary corin levels in patients with chronic kidney disease.

Role of corin and atrial natriuretic peptide in preeclampsia

Role of corin in the regulation of blood pressure

Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy

Role of glycosylation in corin zymogen activation.

Salt-sensitive hypertension and cardiac hypertrophy in transgenic mice expressing a corin variant identified in blacks

Serine proteases and cardiac function.

The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss.

The serine protease corin in cardiovascular biology and disease

Type II transmembrane serine proteases

Upregulation of corin gene expression in hypertrophic cardiomyocytes and failing myocardium

A c.464T>A mutation in VHL gene in a Chinese family with VHL syndrome ⬇️