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List of works by Richard H. Guy

A new system for in vitro studies of iontophoresis

scientific article published in July 1988

A non-rewarding, non-aversive buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm

scientific article

A predictive algorithm for skin permeability: the effects of molecular size and hydrogen bond activity

scientific article

A sweeter life for diabetics? ⬇️

scientific article published on November 1, 1995

Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients

scientific article published on 26 June 2007

Assessing the safety of cosmetic chemicals: Consideration of a flux decision tree to predict dermally delivered systemic dose for comparison with oral TTC (Threshold of Toxicological Concern).

scientific article published on 26 January 2016

Assessment and prediction of the cutaneous bioavailability of topical terbinafine, in vivo, in man

scientific article published on October 1, 2001

Assessment of dermal exposure to pesticide residues during re-entry.

scientific article published on 21 April 2011

Assessment of skin barrier function using transepidermal water loss: effect of age.

scientific article

Assessment of the "skin reservoir" of urea by confocal Raman microspectroscopy and reverse iontophoresis in vivo

scientific article published on 12 May 2007

Bioequivalence Methodologies for Topical Drug Products: In Vitro and Ex Vivo Studies with a Corticosteroid and an Anti-Fungal Drug

scientific article published on 17 January 2017

Biophysical elucidation of the mechanism of enhanced drug release and topical delivery from polymeric film-forming systems

scientific article published on 16 June 2015

Biophysical study of porcine ear skin in vitro and its comparison to human skin in vivo

scientific article published on 01 November 2002

Capillary zone electrophoresis for the estimation of transdermal iontophoretic mobility

scientific article published in December 2005

Characterisation of polyphenolic compounds in Clerodendrum petasites S. Moore and their potential for topical delivery through the skin.

scientific article published on 18 April 2014

Characterisation of skin barrier function using bioengineering and biophysical techniques

scientific article published on 5 August 2014

Characterization of convective solvent flow during iontophoresis.

scientific article

Characterization of the iontophoretic permselectivity properties of human and pig skin

scientific article published on 01 January 2001

Characterization of topical film-forming systems using atomic force microscopy and Raman microspectroscopy

scientific article published on 27 January 2015

Choice of Moisturiser for Eczema Treatment (COMET): study protocol for a randomized controlled trial

scientific article

Comparison of gravimetric and spectroscopic approaches to quantify stratum corneum removed by tape-stripping

scientific article

Comparison of patient (POEM), observer (EASI, SASSAD, TIS) and corneometry measures of emollient effectiveness in children with eczema: findings from the COMET feasibility Trial.

scientific article published on 24 February 2018

Comparison of the lipid composition of porcine buccal and esophageal permeability barriers

scientific article published on 13 June 2005

Contributions of electromigration and electroosmosis to iontophoretic drug delivery.

scientific article published in December 2001

Contributions of electromigration and electroosmosis to peptide iontophoresis across intact and impaired skin

scientific article published on 19 September 2005

Convective solvent flow across the skin during iontophoresis

scientific article published in September 1993

Current status and future prospects of transdermal drug delivery.

scientific article

Cutaneous metabolism of nitroglycerin in vitro. I. Homogenized versus intact skin

scientific article published in February 1992

Cutaneous metabolism of nitroglycerin in vitro. II. Effects of skin condition and penetration enhancement

scientific article published in March 1992

Cutaneous responses to topical methyl nicotinate in black, oriental, and caucasian subjects.

scientific article

Dermal Absorption of Pesticide Residues

scientific article published on 06 December 2018

Dermatopharmacokinetic prediction of topical drug bioavailability in vivo.

scientific article published on 30 November 2006

Dermatopharmacokinetics of betamethasone 17-valerate: influence of formulation viscosity and skin surface cleaning procedure

scientific article

Dermatopharmacokinetics: factors influencing drug clearance from the stratum corneum

scientific article published on 25 November 2008

Development and in vitro evaluation of lipid nanoparticle-based dressings for topical treatment of chronic wounds

scientific article published on 01 June 2015

Development of an in vitro model for premature neonatal skin: biophysical characterization using transepidermal water loss.

scientific article

Development of skin barrier function in premature infants

scientific article

Diagnostic devices: Managing diabetes through the skin

scientific article published on 21 March 2016

Disposition of charged nanoparticles after their topical application to the skin.

scientific article

Disposition of nanoparticles and an associated lipophilic permeant following topical application to the skin.

scientific article published in September 2009

Does epidermal turnover reduce percutaneous penetration?

scientific article published in November 2000

Drug delivery into microneedle-porated nails from nanoparticle reservoirs

scientific article published on 15 October 2015

Drug delivery to the skin from sub-micron polymeric particle formulations: influence of particle size and polymer hydrophobicity.

scientific article

Dye diffusion from microcapsules with different shell thickness into mammalian skin.

scientific article published on 27 November 2008

Effect of Aqueous Cream BP on human stratum corneum in vivo.

scientific article published on November 2010

Effect of amino acid sequence on transdermal iontophoretic peptide delivery.

scientific article

Effect of charge and molecular weight on transdermal peptide delivery by iontophoresis

scientific article published on 26 September 2005

Effect of propylene glycol on ibuprofen absorption into human skin in vivo

scientific article published in January 2008

Effective use of transdermal drug delivery in children.

scientific article published on 11 December 2013

Effects of iontophoresis, hydration, and permeation enhancers on human nail plate: infrared and impedance spectroscopy assessment

scientific article published on 6 March 2013

Effects of various vehicles on skin hydration in vivo

scientific article published on 09 January 2009

Electromigration of ions across the skin: determination and prediction of transport numbers

scientific article published in March 2006

Electroosmosis in transdermal iontophoresis: implications for noninvasive and calibration-free glucose monitoring

scientific article

Electrorepulsion versus electroosmosis: effect of pH on the iontophoretic flux of 5-fluorouracil

scientific article published on 01 May 1999

Emerging strategies for the transdermal delivery of peptide and protein drugs

scientific article published in May 2005

Enhanced delivery of 5-aminolevulinic acid esters by iontophoresis in vitro.

scientific article published in March 2003

Enhanced skin permeation of a lipophilic drug using supersaturated formulations

scientific article published on 01 June 2001

Enhancement of propranolol hydrochloride and diazepam skin absorption in vitro. II: Drug, vehicle, and enhancer penetration kinetics

scientific article published in April 1992

Enhancement of propranolol hydrochloride and diazepam skin absorption in vitro: effect of enhancer lipophilicity

scientific article published in January 1991

Enhancement of topical delivery from biodegradable nanoparticles.

scientific article

Enhancement of transdermal testosterone delivery by supersaturation

scientific article published on 01 November 2006

Epidermal barrier dysfunction in atopic dermatitis.

scientific article published on 04 June 2009

Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies

scientific article published on 11 November 2013

Evaluation of pig esophageal mucosa as a permeability barrier model for buccal tissue

scientific article published in December 2005

Ex vivo evaluation of bioadhesive films for buccal delivery of fentanyl

scientific article

Extraction of amino acids by reverse iontophoresis in vivo.

scientific article

Extraction of amino acids by reverse iontophoresis: simulation of therapeutic monitoring in vitro

scientific article published on 16 July 2008

Femtosecond pulsed laser ablation to enhance drug delivery across the skin

scientific article published on 9 October 2015

Formulation and evaluation of a testosterone transdermal spray

scientific article published on 01 August 2006

Formulation considerations in the design of topical, polymeric film-forming systems for sustained drug delivery to the skin

scientific article published on 14 January 2015

Frequency and thermal effects on the enhancement of transdermal transport by sonophoresis.

scientific article published in February 2003

Ibuprofen delivery into and through the skin from novel oxidized cellulose-based gels and conventional topical formulations

scientific article published on 20 September 2016

Ibuprofen transport into and through skin from topical formulations: in vitro-in vivo comparison

scientific article published on 20 July 2006

Identification of penetration enhancers for testosterone transdermal delivery from spray formulations

scientific article published on 20 March 2006

Imaging Drug Delivery to Skin with Stimulated Raman Scattering Microscopy ⬇️

scientific article published on May 17, 2011

Impact of antinucleants on transdermal delivery of testosterone from a spray

scientific article published in January 2007

Improved bioequivalence assessment of topical dermatological drug products using dermatopharmacokinetics.

scientific article

In Vitro Method to Quantify Dermal Absorption of Pesticide Residues.

scientific article published on 5 February 2015

In situ detection of salicylate in Ocimum basilicum plant leaves via reverse iontophoresis

scientific article published in November 2015

In vivo infrared spectroscopy studies of alkanol effects on human skin

scientific article published on 16 February 2008

In vivo percutaneous absorption of chemicals: a multiple dose study in rhesus monkeys.

scientific article published on February 1990

Influence of ethanol on the solubility, ionization and permeation characteristics of ibuprofen in silicone and human skin

scientific article

Influence of polymer adjuvants on the ultrasound-mediated transfection of cells in culture.

scientific article published on 4 March 2009

Interview with Richard H Guy by Hannah Coaker

scientific article published in February 2014

Iontophoresis of bases, nucleosides, and nucleotides

scientific article published on 01 April 1996

Iontophoresis of dexamethasone phosphate: competition with chloride ions.

scientific article published on 06 July 2008

Iontophoresis of minoxidil sulphate loaded microparticles, a strategy for follicular drug targeting?

scientific article published on 19 July 2015

Iontophoresis of monomeric insulin analogues in vitro: effects of insulin charge and skin pretreatment

scientific article published on 01 January 1998

Iontophoresis of nafarelin across human skin in vitro

scientific article published on 01 May 1996

Iontophoresis of poly-L-lysines: the role of molecular weight?

scientific article published on October 1997

Iontophoresis-targeted, follicular delivery of minoxidil sulfate for the treatment of alopecia

scientific article published on 28 February 2013

Iontophoretic Transdermal Sampling of Iohexol as a Non-Invasive Tool to Assess Glomerular Filtration Rate

scientific article published on 05 September 2014

Iontophoretic delivery across the skin: electroosmosis and its modulation by drug substances.

scientific article published in September 1997

Iontophoretic delivery of a series of tripeptides across the skin in vitro

scientific article published in September 1991

Iontophoretic delivery of amino acids and amino acid derivatives across the skin in vitro

scientific article published on September 1, 1991

Iontophoretic drug delivery.

scientific article published on March 2004

Iontophoretic permselectivity of mammalian skin: characterization of hairless mouse and porcine membrane models

scientific article published on 01 July 1998

Iontophoretic transport pathways: dependence on penetrant physicochemical properties.

scientific article published in December 1997

Kinetic analysis of transdermal nitroglycerin delivery

scientific article published in September 1985

Lithium monitoring by reverse iontophoresis in vivo

scientific article published on 10 June 2004

Malathion percutaneous absorption after repeated administration to man.

scientific article published in March 1983

Mathematical models of skin permeability: An overview ⬇️

scientific article published on February 25, 2011

Measurement and prediction of the rate and extent of drug delivery into and through the skin

scientific article published on 01 April 2009

Mechanical tomography of human corneocytes with a nanoneedle

scientific article published on 06 December 2012

Mechanism of human nail poration by high-repetition-rate, femtosecond laser ablation

scientific article published on 01 October 2019

Metabolic approaches to enhance transdermal drug delivery. 1. Effect of lipid synthesis inhibitors

scientific article published in June 1996

Metals and the skin.

scientific article published on January 1993

Microemulsion formulations for the transdermal delivery of testosterone

scientific article

Modelling drug flux through microporated skin

scientific article

Molecular diffusion in the human nail measured by stimulated Raman scattering microscopy

scientific article

Monitoring of urea and potassium by reverse iontophoresis in vitro

scientific article published on 23 March 2007

Non-invasive assessment of the effect of formulation excipients on stratum corneum barrier function in vivo.

scientific article published on March 2004

Non-invasive assessment of the effects of iontophoresis on human skin in-vivo.

scientific article

Non-invasive diagnosis and monitoring of chronic kidney disease by reverse iontophoresis of urea in vivo

scientific article published on 20 February 2008

Non-invasive monitoring of phenytoin by reverse iontophoresis

scientific article

Non-invasive, transdermal, path-selective and specific glucose monitoring via a graphene-based platform

scientific article published on 09 April 2018

Noninvasive glucose monitoring by reverse iontophoresis in vivo: application of the internal standard concept

scientific article

Noninvasive sampling of phenylalanine by reverse iontophoresis

scientific article published on 01 August 1999

Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug

scientific article published on 02 August 2007

Novel imaging method to quantify stratum corneum in dermatopharmacokinetic studies

scientific article published on 05 May 2012

Novel imaging method to quantify stratum corneum in dermatopharmacokinetic studies: proof-of-concept with acyclovir formulations

scientific article published on 19 July 2012

Objective assessment of nanoparticle disposition in mammalian skin after topical exposure

scientific article published on 23 June 2012

Optimisation of Cosolvent Concentration for Topical Drug Delivery III – Influence of Lipophilic Vehicles on Ibuprofen Permeation

scientific article published on 09 July 2010

Optimisation of cosolvent concentration for topical drug delivery - II: influence of propylene glycol on ibuprofen permeation.

scientific article published on 31 July 2009

Optimization of aminolevulinic acid delivery by iontophoresis

scientific article published in February 2003

Optimization of in vitro flux through hairless mouse skin of cidofovir, a potent nucleotide analog

scientific article published in June 1995

Optimization of topical therapy: partitioning of drugs into stratum corneum

scientific article

Optimizing iontophoretic drug delivery: identification and distribution of the charge-carrying species.

scientific article published in December 2001

Optimizing metrics for the assessment of bioequivalence between topical drug products.

scientific article published in May 2008

Partitioning of chemicals into human stratum corneum: implications for risk assessment following dermal exposure

scientific article

Passive and iontophoretic transdermal delivery of phenobarbital: Implications in paediatric therapy

scientific article published on 23 February 2012

Percutaneous absorption in man: a kinetic approach

journal article published in 1985

Percutaneous absorption of 4-cyanophenol from freshly contaminated soil in vitro: effects of soil loading and contamination concentration.

scientific article published in May 2005

Percutaneous penetration enhancement in vivo measured by attenuated total reflectance infrared spectroscopy.

scientific article published on August 1990

Percutaneous penetration kinetics of nitroglycerin and its dinitrate metabolites across hairless mouse skin in vitro

scientific article

Percutaneous penetration of nicotinates: in vivo and in vitro measurements

journal article published in 1986

Percutaneous penetration of para-substituted phenols in vitro

scientific article published in October 1991

Permeation of a myristoylated dipeptide across the buccal mucosa: topological distribution and evaluation of tissue integrity.

scientific article published in January 2002

Perturbation of solute transport at a liquid-liquid interface by polyethylene glycol (PEG): implications for PEG-induced biomembrane fusion

scientific article published on 01 February 2011

Pharmacodynamic measurements of methyl nicotinate percutaneous absorption.

scientific article

Pharmacodynamics and dermatopharmacokinetics of betamethasone 17-valerate: assessment of topical bioavailability

scientific article

Physicochemical aspects of percutaneous penetration and its enhancement

journal article published in 1988

Physicochemical interpretation of the pharmacokinetics of percutaneous absorption

scientific article published in April 1983

Pig ear skin ex vivo as a model for in vivo dermatopharmacokinetic studies in man.

scientific article published in August 2006

Piroxicam delivery into human stratum corneum in vivo: iontophoresis versus passive diffusion.

scientific article

Plasma membrane poration induced by ultrasound exposure: implication for drug delivery.

scientific article

Porcine ear skin as a model for the assessment of transdermal drug delivery to premature neonates.

scientific article published in August 2004

Post-iontophoresis recovery of human skin impedance in vivo

scientific article published on 01 January 2002

Potential of iontophoresis as a drug delivery method for midazolam in pediatrics

scientific article published on 30 November 2018

Precise laser poration to control drug delivery into and through human nail

scientific article published on 16 October 2017

Predicting the rate and extent of fragrance chemical absorption into and through the skin

scientific article published in May 2010

Predicting topical drug clearance from the skin

scientific article published on 08 November 2020

Prediction of chemical absorption into and through the skin from cosmetic and dermatological formulations

scientific article

Prediction of iontophoretic transport across the skin

scientific article published on 20 February 2006

Preliminary skin blood flow measurements appear unsuccessful for assessing topical corticosteroid effect

scientific article published on 01 January 1983

Preparation and in vitro evaluation of topical formulations based on polystyrene-poly-2-hydroxyl methacrylate nanoparticles.

scientific article published in September 2009

Products in "Bounty bags" potentially harm newborn skin.

scientific article

Quantitative structure-permeation relationship for iontophoretic transport across the skin

scientific article

Quantitative structure-permeation relationships (QSPeRs) to predict skin permeation: a critical evaluation.

scientific article published on January 2004

Quantitative structure-permeation relationships for solute transport across silicone membranes

scientific article published in November 2002

Rapid radial transport of methyl nicotinate in the dermis

scientific article published in January 1982

Recovery of human skin impedance in vivo after lontophoresis: Effect of metal ions ⬇️

scientific article published on January 1, 2000

Regulatory Science and Innovation Programme for Europe (ReScIPE): A proposed model

scientific article published on 19 August 2019

Reverse Iontophoresis for Noninvasive Glucose Monitoring: The Internal Standard Concept ⬇️

scientific article published on November 1, 2003

Reverse Iontophoretic Extraction of Metabolites from Living Plants and their Identification by Ion-chromatography Coupled to High Resolution Mass Spectrometry

scientific article published on 28 December 2016

Reverse iontophoresis as a noninvasive tool for lithium monitoring and pharmacokinetic profiling

scientific article published on 01 July 2004

Reverse iontophoresis for non-invasive transdermal monitoring.

scientific article published in June 2004

Reverse iontophoresis of L-lactate: in vitro and in vivo studies

scientific article published in December 2007

Reverse iontophoresis of amino acids: identification and separation of stratum corneum and subdermal sources in vitro.

scientific article published on 6 October 2009

Reverse iontophoresis of lithium: electrode formulation using a thermoreversible polymer

scientific article published in January 2005

Reverse iontophoresis: development of a noninvasive approach for glucose monitoring.

scientific article published in December 1993

Reverse iontophoresis: noninvasive glucose monitoring in vivo in humans

scientific article published in December 1995

Scanning the horizon: a systematic literature review of methodologies.

scientific article published on 27 May 2019

Serious photocontact dermatitis induced by topical ketoprofen depends on the formulation

scientific article published on 01 May 2014

Simultaneous Transdermal Delivery of Buprenorphine Hydrochloride and Naltrexone Hydrochloride by Iontophoresis

scientific article published on 22 May 2019

Simultaneous extraction of urea and glucose by reverse iontophoresis in vivo

scientific article published in October 2004

Skin - ‘That Unfakeable Young Surface' ⬇️

scientific article published on July 29, 2013

Sonophoresis. I. The use of high-frequency ultrasound to enhance transdermal drug delivery

scientific article published on April 1, 1992

Sonophoresis. II. Examination of the mechanism(s) of ultrasound-enhanced transdermal drug delivery

scientific article published in August 1992

Stabilization of supersaturated solutions of a lipophilic drug for dermal delivery.

scientific article published in August 2001

Stratum corneum lipids of human epidermal keratinocyte air-liquid cultures: implications for barrier function

scientific article published on 01 August 1996

Stratum corneum thickness and apparent water diffusivity: facile and noninvasive quantitation in vivo

scientific article published on 01 March 1998

Structure-permeability relationships in percutaneous penetration

scientific article published on June 1, 1992

Structure-permeation relationships for the non-invasive transdermal delivery of cationic peptides by iontophoresis

scientific article published on 03 June 2006

Supersaturation: enhancement of skin penetration and permeation of a lipophilic drug.

scientific article

The European Medicines Agency's goals for regulatory science to 2025

scientific article published on 01 June 2019

The determination of a diffusional pathlength through the stratum corneum.

scientific article published in October 1999

The effect of current on skin barrier function in vivo: recovery kinetics post-iontophoresis.

scientific article published on September 1997

The effect of iontophoresis on skin barrier integrity: non-invasive evaluation by impedance spectroscopy and transepidermal water loss.

scientific article published in June 1996

The effects of zwitterionic surfactants on skin barrier function

scientific article

The electrical characteristics of human skin in vivo

scientific article published on 01 November 1995

The influence of molecular volume and hydrogen-bonding on peptide transport across epithelial membranes

scientific article published on 01 April 1993

The influence of urea on percutaneous absorption

scientific article published on 01 October 1986

The potential of polymeric film-forming systems as sustained delivery platforms for topical drugs

scientific article

The relationship between pKa and skin irritation for a series of basic penetrants in man.

scientific article published in November 1990

The relationship of pKa and acute skin irritation in man

scientific article published on 01 October 1988

Topical bio(in)equivalence of metronidazole formulations in vivo

scientific article published on 17 February 2018

Topical bioavailability of diclofenac from locally-acting, dermatological formulations.

scientific article published on 18 June 2017

Topical formulation and dermal delivery of active phenolic compounds in the Thai medicinal plant--Clerodendrum petasites S. Moore.

scientific article published on 6 November 2014

Topical iontophoresis of valaciclovir hydrochloride improves cutaneous aciclovir delivery

scientific article published in August 2006

Trans-scleral iontophoretic delivery of low molecular weight therapeutics.

scientific article published on 23 July 2010

Transdermal drug delivery

scientific article published on 01 January 2010

Transdermal drug delivery. Clinical aspects ⬇️

scientific article published on 01 April 1998

Transdermal drug delivery: 30+ years of war and still fighting!

scientific article published on 19 May 2014

Transdermal drug delivery: overcoming the skin's barrier function

scientific article published on 01 September 2000

Transdermal flux predictions for selected selective oestrogen receptor modulators (SERMs): comparison with experimental results.

scientific article published on 27 September 2013

Transdermal iontophoresis of ranitidine: an opportunity in paediatric drug therapy

scientific article published on 13 March 2012

Transdermal iontophoresis: modulation of electroosmosis by polypeptide

scientific article published in January 1998

Transdermal iontophoretic delivery of triptorelin in vitro.

scientific article published in October 2005

Transdermal iontophoretic delivery of vapreotide acetate across porcine skin in vitro

scientific article published on 3 August 2005

Transdermal reverse iontophoresis of valproate: a noninvasive method for therapeutic drug monitoring.

scientific article published in September 2003

Transdermal therapy and diagnosis by iontophoresis ⬇️

scientific article published on August 1, 1997

Transport numbers in transdermal iontophoresis.

scientific article

Ultrasound-enhanced transdermal transport.

scientific article

Ultrasound-mediated gene delivery: influence of contrast agent on transfection

scientific article published on 10 April 2007

Uptake of microemulsion components into the stratum corneum and their molecular effects on skin barrier function

scientific article published on 01 August 2010

Uptake of two zwitterionic surfactants into human skin in vivo.

scientific article published in June 1993

Validation of reflectance infrared spectroscopy as a quantitative method to measure percutaneous absorption in vivo

scientific article published in October 1993

Visualization of skin penetration using confocal laser scanning microscopy.

scientific article

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