List of works - Enzo Tramontano

(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase

scientific article published on 20 February 2015

1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity

scientific article published on 05 March 2020

2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays

scientific article published on January 2004

2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication

scientific article published on 15 March 2020

5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives

scientific article

6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach

scientific article published on 5 November 2013

6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro

scientific article

6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays

scientific article published in April 2004

A new vinyl selenone-based domino approach to spirocyclopropyl oxindoles endowed with anti-HIV RT activity

scientific article published on 12 January 2016

Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase

scientific article published on December 2013

Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases

scientific article published on 16 March 2011

An Efficient Route to Novel Uracil-Based Drug-Like Molecules

article published in 2015

Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors

scientific article

Antitumor agents. 1. Synthesis, biological evaluation, and molecular modeling of 5H-pyrido[3,2-a]phenoxazin-5-one, a compound with potent antiproliferative activity

scientific article published in November 2002

Antiviral Agents Against Ebola Virus Infection: Repositioning Old Drugs and Finding Novel Small Molecules

scientific article published in 2018

Biochemical Characterization of the HIV-1 Integrase 3‘-Processing Activity and Its Inhibition by Phosphorothioate Oligonucleotides ⬇️

scientific article published on May 19, 1998

Biochemical characterization of HIV-1 reverse transcriptases encoding mutations at amino acid residues 161 and 208 involved in resistance to phosphonoformate.

scientific article published on December 1998

Biological Activities of Aerial Parts Extracts of Euphorbia characias.

scientific article published on 24 May 2016

Broad-range potential of Asphodelus microcarpus leaves extract for drug development

scientific article

Chelation Motifs Affecting Metal-dependent Viral Enzymes: N'-acylhydrazone Ligands as Dual Target Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain

scientific article published on 20 March 2017

Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity

scientific article published on 12 August 2019

Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci

scientific article published on 23 April 2020

Comprehensive Characterization of the Human Endogenous Retrovirus HERV-K(HML-6) Group: Overview of Structure, Phylogeny, and Contribution to the Human Genome

scientific article published on 30 July 2019

Contribution of Human Retroviruses to Disease Development-A Focus on the HIV- and HERV-Cancer Relationships and Treatment Strategies

scientific article published on 04 August 2020

Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes

scientific article published on 9 September 2016

Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production

scientific article published in 2022

Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.

scientific article published on August 2017

Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase.

scientific article

Development and Identification of a Novel Anti-HIV-1 Peptide Derived by Modification of the N-Terminal Domain of HIV-1 Integrase.

scientific article

Development and Validation of a Novel Dual Luciferase Reporter Gene Assay to Quantify Ebola Virus VP24 Inhibition of IFN Signaling

scientific article published on 24 February 2018

Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity

scientific article published on 30 April 2012

Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors

scientific article published on 05 December 2019

Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy).

scientific article published on 4 February 2018

Ebola virus VP35 blocks stress granule assembly.

scientific article published on 22 December 2016

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

article

From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors.

scientific article

Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.

scientific article published on October 1998

HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity.

scientific article published on 14 March 2018

HERV-W group evolutionary history in non-human primates: characterization of ERV-W orthologs in Catarrhini and related ERV groups in Platyrrhini

scientific article published on 19 January 2018

HIV-1 RNase H: recent progress in an exciting, yet little explored, drug target.

scientific article published on June 2006

HIV-1 RT-Associated RNase H Function Inhibitors: Recent Advances in Drug Development ⬇️

scientific article published on January 1, 2010

HIV-1 Reverse Transcriptase Still Remains a New Drug Target: Structure, Function, Classical Inhibitors, and New Inhibitors with Innovative Mechanisms of Actions ⬇️

scientific article published on June 20, 2012

HIV-1 reverse transcriptase inhibition by a dipyridodiazepinone derivative: BI-RG-587

scientific article (publication date: 17 March 1992)

HIV-1-inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata

scientific article (publication date: October 2009)

Human Endogenous Retroviruses Are Ancient Acquired Elements Still Shaping Innate Immune Responses

article

Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities.

scientific article

Identification and characterization of ERV-W-like sequences in Platyrrhini species provides new insights into the evolutionary history of ERV-W in primates

scientific article published on 01 February 2020

Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach

scientific article

Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay

article

Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion

scientific article published on 2 November 2017

Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives

scientific article

Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate. Implications for multiple drug resistance.

scientific article published on December 1993

Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops.

scientific article published on 10 May 2018

Inhibition of HIV-1 Reverse Transcriptase Dimerization by Small Molecules

scientific article

Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds

scientific article published on July 2011

Inhibition of foamy virus reverse transcriptase by human immunodeficiency virus type 1 RNase H inhibitors

scientific article

Inhibitory Effect of 2,3,5,6-Tetrafluoro-4-[4-(aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide Derivatives on HIV Reverse Transcriptase Associated RNase H Activities.

scientific article published on 20 August 2016

Insights into Ebola Virus VP35 and VP24 Interferon inhibitory functions and their initial exploitation as drug targets

scientific article published on 01 January 2019

Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein.

scientific article published on 7 February 2018

Intracellular human antibody fragments recognizing the VP35 protein of Zaire Ebola filovirus inhibit the protein activity

scientific article published on 05 September 2019

Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments

scientific article published on 15 May 2015

Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase.

scientific article published on 21 October 2016

Meeting report: 32nd International Conference on Antiviral Research

scientific article published on 11 July 2019

Meeting report: Fourth Summer School on Innovative Approaches for Identification of Antiviral Agents (IAAASS)

scientific article published on 23 December 2018

Meeting report: Third Summer School on Innovative Approaches for Identification of Antiviral Agents (IAAASS).

scientific article published on 8 December 2016

Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action.

scientific article published in August 2017

Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding.

scientific article published on 19 December 2016

Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase

scientific article published on 24 February 2017

New Anthraquinone Derivatives as Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Function

article

New features of the cell wall of the radio-resistant bacterium Deinococcus radiodurans

scientific article published on 28 February 2014

On the S-layer of Thermus thermophilus and the assembling of its main protein SlpA

scientific article published on 25 May 2018

Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors

scientific article published on 29 January 2014

Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication

scientific article published on 30 March 2018

Probing the Importance of the G-Quadruplex Grooves for the Activity of the Anti-HIV-Integrase Aptamer T30923

scientific article published on 06 August 2020

Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans

scientific article published on 3 June 2015

Purification and functional characterization of the full length recombinant Ebola virus VP35 protein expressed in E. coli

scientific article published on 20 February 2009

Pyrazole-related nucleosides. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides

scientific article (publication date: 6 March 1992)

Pyrosequencing of the Camptotheca acuminata transcriptome reveals putative genes involved in camptothecin biosynthesis and transport ⬇️

scientific article published on October 30, 2011

RNA-seq transcriptome analysis reveals LTR-retrotransposons modulation in Human Peripheral Blood Mononuclear Cells (PBMCs) after in vivo Lipopolysaccharides (LPS) injection

scientific article published on 15 July 2020

Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition

scientific article published on 01 January 2019

Ribonuclease H, an unexploited target for antiviral intervention against HIV and hepatitis B virus

scientific article published on 21 September 2019

Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H

scientific article published on 01 December 2020

Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication

scientific article

Strategies of highly pathogenic RNA viruses to block dsRNA detection by RIG-I-like receptors: hide, mask, hit.

scientific article published on 12 October 2013

Structure-activity relationship of pyrrolyl diketo acid derivatives as dual inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease H domain

scientific article published on 11 February 2015

Structure-guided approach identifies a novel class of HIV-1 ribonuclease H inhibitors: binding mode insights through magnesium complexation and site-directed mutagenesis studies

article

Synthesis and anti-HIV-1 activity of thio analogues of dihydroalkoxybenzyloxopyrimidines.

scientific article published on August 1995

Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of isoddA and their phosphates as prodrugs.

scientific article published on October 1994

Synthesis of new disoxaril analogues with potent and selective anti-human rhinovirus 14 activity

scientific article published in 1991

Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants

scientific article published on 06 July 2020

Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach

scientific article published on 3 November 2022

The exploding field of the HCV polymerase non-nucleoside inhibitors: summary of a first generation compounds.

scientific article published on October 2008

The use of a new in vitro reaction substrate reproducing both U3 and U5 regions of the HIV-1 3'-ends increases the correlation between the in vitro and in vivo effects of the HIV-1 integrase inhibitors

scientific article published in May 2004

Type W Human Endogenous Retrovirus (HERV-W) Integrations and Their Mobilization by L1 Machinery: Contribution to the Human Transcriptome and Impact on the Host Physiopathology.

scientific article published on 27 June 2017

Uvaria angolensis as a promising source of inhibitors of HIV-1 RT-associated RNA-dependent DNA polymerase and RNase H functions.

scientific article published on 25 May 2017

Validation of a computed radiography device to monitor the HIV-1 RNase H activity

article

ZnO-mediated regioselective C-arylsulfonylation of indoles: a facile solvent-free synthesis of 2- and 3-sulfonylindoles and preliminary evaluation of their activity against drug-resistant mutant HIV-1 reverse transcriptases (RTs)

article

dsRNA binding characterization of full length recombinant wild type and mutants Zaire ebolavirus VP35.

scientific article published on 25 January 2012

List of works by Enzo Tramontano

(3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase

1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity

2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays

2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication

5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives

6-(1-Benzyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acids as dual inhibitors of recombinant HIV-1 integrase and ribonuclease H, synthesized by a parallel synthesis approach

6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro

6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays

A new vinyl selenone-based domino approach to spirocyclopropyl oxindoles endowed with anti-HIV RT activity

Active site and allosteric inhibitors of the ribonuclease H activity of HIV reverse transcriptase

Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases

An Efficient Route to Novel Uracil-Based Drug-Like Molecules

Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors

Antitumor agents. 1. Synthesis, biological evaluation, and molecular modeling of 5H-pyrido[3,2-a]phenoxazin-5-one, a compound with potent antiproliferative activity

Antiviral Agents Against Ebola Virus Infection: Repositioning Old Drugs and Finding Novel Small Molecules

Biochemical Characterization of the HIV-1 Integrase 3‘-Processing Activity and Its Inhibition by Phosphorothioate Oligonucleotides ⬇️

Biochemical characterization of HIV-1 reverse transcriptases encoding mutations at amino acid residues 161 and 208 involved in resistance to phosphonoformate.

Biological Activities of Aerial Parts Extracts of Euphorbia characias.

Broad-range potential of Asphodelus microcarpus leaves extract for drug development

Chelation Motifs Affecting Metal-dependent Viral Enzymes: N'-acylhydrazone Ligands as Dual Target Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain

Chromenone derivatives as a versatile scaffold with dual mode of inhibition of HIV-1 reverse transcriptase-associated Ribonuclease H function and integrase activity

Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci

Comprehensive Characterization of the Human Endogenous Retrovirus HERV-K(HML-6) Group: Overview of Structure, Phylogeny, and Contribution to the Human Genome

Contribution of Human Retroviruses to Disease Development-A Focus on the HIV- and HERV-Cancer Relationships and Treatment Strategies

Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes

Cynarin blocks Ebola virus replication by counteracting VP35 inhibition of interferon-beta production

Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.

Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase.

Development and Identification of a Novel Anti-HIV-1 Peptide Derived by Modification of the N-Terminal Domain of HIV-1 Integrase.

Development and Validation of a Novel Dual Luciferase Reporter Gene Assay to Quantify Ebola Virus VP24 Inhibition of IFN Signaling

Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity

Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors

Dual HIV-1 reverse transcriptase and integrase inhibitors from Limonium morisianum Arrigoni, an endemic species of Sardinia (Italy).

Ebola virus VP35 blocks stress granule assembly.

From cycloheptathiophene-3-carboxamide to oxazinone-based derivatives as allosteric HIV-1 ribonuclease H inhibitors

From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors.

Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.

HERV Envelope Proteins: Physiological Role and Pathogenic Potential in Cancer and Autoimmunity.

HERV-W group evolutionary history in non-human primates: characterization of ERV-W orthologs in Catarrhini and related ERV groups in Platyrrhini

HIV-1 RNase H: recent progress in an exciting, yet little explored, drug target.

HIV-1 RT-Associated RNase H Function Inhibitors: Recent Advances in Drug Development ⬇️

HIV-1 Reverse Transcriptase Still Remains a New Drug Target: Structure, Function, Classical Inhibitors, and New Inhibitors with Innovative Mechanisms of Actions ⬇️

HIV-1 reverse transcriptase inhibition by a dipyridodiazepinone derivative: BI-RG-587

HIV-1-inhibiting activity of the essential oil of Ridolfia segetum and Oenanthe crocata

Human Endogenous Retroviruses Are Ancient Acquired Elements Still Shaping Innate Immune Responses

Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H activities.

Identification and characterization of ERV-W-like sequences in Platyrrhini species provides new insights into the evolutionary history of ERV-W in primates

Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach

Identification of Myricetin as Ebolavirus VP35-dsRNA interaction inhibitor through a novel fluorescence-based assay

Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion

Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by Diketo acid derivatives

Identification of the amino acid in the human immunodeficiency virus type 1 reverse transcriptase involved in the pyrophosphate binding of antiviral nucleoside triphosphate analogs and phosphonoformate. Implications for multiple drug resistance.

Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops.

Inhibition of HIV-1 Reverse Transcriptase Dimerization by Small Molecules

Inhibition of HIV-1 reverse transcriptase associated activities by the hydroalcoholic extract of Casimiroa edulis seeds

Inhibition of foamy virus reverse transcriptase by human immunodeficiency virus type 1 RNase H inhibitors

Inhibitory Effect of 2,3,5,6-Tetrafluoro-4-[4-(aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide Derivatives on HIV Reverse Transcriptase Associated RNase H Activities.

Insights into Ebola Virus VP35 and VP24 Interferon inhibitory functions and their initial exploitation as drug targets

Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein.

Intracellular human antibody fragments recognizing the VP35 protein of Zaire Ebola filovirus inhibit the protein activity

Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments

Isatin thiazoline hybrids as dual inhibitors of HIV-1 reverse transcriptase.

Meeting report: 32nd International Conference on Antiviral Research

Meeting report: Fourth Summer School on Innovative Approaches for Identification of Antiviral Agents (IAAASS)

Meeting report: Third Summer School on Innovative Approaches for Identification of Antiviral Agents (IAAASS).

Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action.

Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding.

Natural product-inspired esters and amides of ferulic and caffeic acid as dual inhibitors of HIV-1 reverse transcriptase

New Anthraquinone Derivatives as Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Function

New features of the cell wall of the radio-resistant bacterium Deinococcus radiodurans

On the S-layer of Thermus thermophilus and the assembling of its main protein SlpA

Past and future. Current drugs targeting HIV-1 integrase and reverse transcriptase-associated ribonuclease H activity: single and dual active site inhibitors

Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication

Probing the Importance of the G-Quadruplex Grooves for the Activity of the Anti-HIV-Integrase Aptamer T30923

Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans

Purification and functional characterization of the full length recombinant Ebola virus VP35 protein expressed in E. coli

Pyrazole-related nucleosides. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides

Pyrosequencing of the Camptotheca acuminata transcriptome reveals putative genes involved in camptothecin biosynthesis and transport ⬇️

RNA-seq transcriptome analysis reveals LTR-retrotransposons modulation in Human Peripheral Blood Mononuclear Cells (PBMCs) after in vivo Lipopolysaccharides (LPS) injection