List of works - Marcello Solinas

Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation

scientific article published in November 2004

An improved within-session self-adjusting delay discounting procedure for the study of choice impulsivity in rats

scientific article published on 30 April 2018

Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats

scientific article published in July 2006

Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis

scientific article

Behavioral flexibility predicts increased ability to resist excessive methamphetamine self-administration.

scientific article published on 9 March 2016

Behavioural sensitization after repeated exposure to Delta 9-tetrahydrocannabinol and cross-sensitization with morphine.

scientific article

Beta-endorphin elevations in the ventral tegmental area regulate the discriminative effects of Delta-9-tetrahydrocannabinol.

scientific article

Brain regions associated with the reversal of cocaine conditioned place preference by environmental enrichment

scientific article published on 6 April 2011

Cannabinoid agonists but not inhibitors of endogenous cannabinoid transport or metabolism enhance the reinforcing efficacy of heroin in rats

scientific article published in November 2005

Cannabinoid facilitation of behavioral and biochemical hedonic taste responses

scientific article

Chronic stimulation of the tone of endogenous anandamide reduces cue- and stress-induced relapse in rats

scientific article

Continuous theta burst stimulation over the supplementary motor area in refractory obsessive-compulsive disorder treatment: A randomized sham-controlled trial

scientific article published on 25 July 2019

Dopamine and addiction: what have we learned from 40 years of research

scientific article published on 19 December 2018

Early exposure to environmental enrichment alters the expression of genes of the endocannabinoid system.

scientific article published on 16 March 2011

Effect of 3,4-methylendioxymethamphetamine (MDMA, "ecstasy") on dopamine transmission in the nucleus accumbens shell and core.

scientific article published in September 2005

Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders.

scientific article published on 15 May 2008

Effects of environmental enrichment on the incubation of cocaine craving.

scientific article

Endocannabinoid system involvement in brain reward processes related to drug abuse

scientific article

Environmental enrichment decreases the rewarding but not the activating effects of heroin.

scientific article

Environmental enrichment does not reduce the rewarding and neurotoxic effects of methamphetamine.

scientific article published on 9 February 2010

Environmental enrichment during adolescence regulates gene expression in the striatum of mice

scientific article published on 20 May 2008

Exposure to delta-9-tetrahydrocannabinol (THC) increases subsequent heroin taking but not heroin's reinforcing efficacy: a self-administration study in rats

scientific article published on July 2004

Exposure to sucrose during periods of withdrawal does not reduce cocaine-seeking behavior in rats.

scientific article published on 21 March 2016

Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors.

scientific article published on 29 April 2009

Generalization of effects of environmental enrichment on seeking for different classes of drugs of abuse.

scientific article published on 27 December 2017

Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release.

scientific article published on 17 May 2006

Human cocaine-seeking behavior and its control by drug-associated stimuli in the laboratory

scientific article published in February 2005

Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats

scientific article published on 13 October 2003

Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration

scientific article

Involvement of adenosine A1 receptors in the discriminative-stimulus effects of caffeine in rats

scientific article published on 5 February 2005

Involvement of mu-, delta- and kappa-opioid receptor subtypes in the discriminative-stimulus effects of delta-9-tetrahydrocannabinol (THC) in rats

scientific article published on 24 December 2004

Lack of effects of simvastatin on smoking cessation in humans: A double-blind, randomized, placebo-controlled clinical study

scientific article published in March 2018

Longitudinal Changes in Brain Metabolic Activity after Withdrawal from Escalation of Cocaine Self-Administration.

scientific article published on 29 May 2017

Loss of Environmental Enrichment Increases Vulnerability to Cocaine Addiction

Loss of environmental enrichment increases vulnerability to cocaine addiction

scientific article published on 01 February 2014

Motivational effects of cannabinoids and opioids on food reinforcement depend on simultaneous activation of cannabinoid and opioid systems

scientific article published in November 2005

Neuropeptide Y protects against methamphetamine-induced neuronal apoptosis in the mouse striatum.

scientific article published in June 2005

Nicotinic alpha 7 receptors as a new target for treatment of cannabis abuse

scientific article

Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamide

scientific article published on 9 March 2007

Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure

scientific article published in March 2004

Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats

scientific article

Prevention and treatment of drug addiction by environmental enrichment.

scientific article published on 14 August 2010

Previous exposure to THC alters the reinforcing efficacy and anxiety-related effects of cocaine in rats

scientific article published on 31 May 2006

Prior exposure to THC increases the addictive effects of nicotine in rats.

scientific article

Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

scientific article published on 05 April 2014

Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humans

scientific article published on 19 December 2012

Psychostimulant sensitization: differential changes in accumbal shell and core dopamine

scientific article published in January 2000

Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid

scientific article published on 13 October 2013

Reversal of cocaine addiction by environmental enrichment.

scientific article

Selective psychostimulant sensitization by food restriction: differential changes in accumbens shell and core dopamine.

scientific article published in October 2003

Statins Reduce the Risks of Relapse to Addiction in Rats

scientific article published on 15 October 2015

The cannabinoid CB1 antagonist N-piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl) -4-methylpyrazole-3-carboxamide (SR-141716A) differentially alters the reinforcing effects of heroin under continuous reinforcement, fixed ratio, and progressive

scientific article published on 26 March 2003

The endocannabinoid system in brain reward processes

scientific article published on 14 April 2008

The endogenous cannabinoid anandamide and its synthetic analog R(+)-methanandamide are intravenously self-administered by squirrel monkeys

scientific article published on June 2005

The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport

scientific article published on 8 January 2007

Two brain sites for cannabinoid reward.

scientific article published in May 2006

Using drug-discrimination techniques to study the abuse-related effects of psychoactive drugs in rats

scientific article published in January 2006

List of works by Marcello Solinas

Adenosine receptor-mediated modulation of dopamine release in the nucleus accumbens depends on glutamate neurotransmission and N-methyl-D-aspartate receptor stimulation

An improved within-session self-adjusting delay discounting procedure for the study of choice impulsivity in rats

Anandamide administration alone and after inhibition of fatty acid amide hydrolase (FAAH) increases dopamine levels in the nucleus accumbens shell in rats

Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis

Behavioral flexibility predicts increased ability to resist excessive methamphetamine self-administration.

Behavioural sensitization after repeated exposure to Delta 9-tetrahydrocannabinol and cross-sensitization with morphine.

Beta-endorphin elevations in the ventral tegmental area regulate the discriminative effects of Delta-9-tetrahydrocannabinol.

Brain regions associated with the reversal of cocaine conditioned place preference by environmental enrichment

Cannabinoid agonists but not inhibitors of endogenous cannabinoid transport or metabolism enhance the reinforcing efficacy of heroin in rats

Cannabinoid facilitation of behavioral and biochemical hedonic taste responses

Chronic stimulation of the tone of endogenous anandamide reduces cue- and stress-induced relapse in rats

Continuous theta burst stimulation over the supplementary motor area in refractory obsessive-compulsive disorder treatment: A randomized sham-controlled trial

Dopamine and addiction: what have we learned from 40 years of research

Early exposure to environmental enrichment alters the expression of genes of the endocannabinoid system.

Effect of 3,4-methylendioxymethamphetamine (MDMA, "ecstasy") on dopamine transmission in the nucleus accumbens shell and core.

Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders.

Effects of environmental enrichment on the incubation of cocaine craving.

Endocannabinoid system involvement in brain reward processes related to drug abuse

Environmental enrichment decreases the rewarding but not the activating effects of heroin.

Environmental enrichment does not reduce the rewarding and neurotoxic effects of methamphetamine.

Environmental enrichment during adolescence regulates gene expression in the striatum of mice

Exposure to delta-9-tetrahydrocannabinol (THC) increases subsequent heroin taking but not heroin's reinforcing efficacy: a self-administration study in rats

Exposure to sucrose during periods of withdrawal does not reduce cocaine-seeking behavior in rats.

Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-alpha nuclear receptors.

Generalization of effects of environmental enrichment on seeking for different classes of drugs of abuse.

Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release.

Human cocaine-seeking behavior and its control by drug-associated stimuli in the laboratory

Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats

Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration

Involvement of adenosine A1 receptors in the discriminative-stimulus effects of caffeine in rats

Involvement of mu-, delta- and kappa-opioid receptor subtypes in the discriminative-stimulus effects of delta-9-tetrahydrocannabinol (THC) in rats

Lack of effects of simvastatin on smoking cessation in humans: A double-blind, randomized, placebo-controlled clinical study

Longitudinal Changes in Brain Metabolic Activity after Withdrawal from Escalation of Cocaine Self-Administration.

Loss of Environmental Enrichment Increases Vulnerability to Cocaine Addiction

Loss of environmental enrichment increases vulnerability to cocaine addiction

Motivational effects of cannabinoids and opioids on food reinforcement depend on simultaneous activation of cannabinoid and opioid systems

Neuropeptide Y protects against methamphetamine-induced neuronal apoptosis in the mouse striatum.

Nicotinic alpha 7 receptors as a new target for treatment of cannabis abuse

Nicotinic facilitation of delta9-tetrahydrocannabinol discrimination involves endogenous anandamide

Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure

Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats

Prevention and treatment of drug addiction by environmental enrichment.

Previous exposure to THC alters the reinforcing efficacy and anxiety-related effects of cocaine in rats

Prior exposure to THC increases the addictive effects of nicotine in rats.

Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humans

Psychostimulant sensitization: differential changes in accumbal shell and core dopamine

Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid

Reversal of cocaine addiction by environmental enrichment.

Selective psychostimulant sensitization by food restriction: differential changes in accumbens shell and core dopamine.

Statins Reduce the Risks of Relapse to Addiction in Rats

The cannabinoid CB1 antagonist N-piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl) -4-methylpyrazole-3-carboxamide (SR-141716A) differentially alters the reinforcing effects of heroin under continuous reinforcement, fixed ratio, and progressive

The endocannabinoid system in brain reward processes

The endogenous cannabinoid anandamide and its synthetic analog R(+)-methanandamide are intravenously self-administered by squirrel monkeys

The endogenous cannabinoid anandamide produces delta-9-tetrahydrocannabinol-like discriminative and neurochemical effects that are enhanced by inhibition of fatty acid amide hydrolase but not by inhibition of anandamide transport

Two brain sites for cannabinoid reward.

Using drug-discrimination techniques to study the abuse-related effects of psychoactive drugs in rats