List of works - Christopher J. Molloy

A functional radioreceptor assay of alpha-V-beta-3 (alphavbeta3) inhibitors in plasma: application as an ex vivo pharmacodynamic model

scientific article published on 21 November 2005

A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s.

scientific article published on 3 February 2006

Activin A and TGF-beta stimulate phosphorylation of focal adhesion proteins and cytoskeletal reorganization in rat aortic smooth muscle cells

scientific article published on 01 August 1999

Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s.

scientific article

Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor

scientific article published on 7 February 2008

Design and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s

scientific article published on 16 June 2012

Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.

scientific article published in February 2005

Discovery of novel FMS kinase inhibitors as anti-inflammatory agents

scientific article published on 19 January 2008

Effect of retinoid deficiency on keratin expression in mouse bladder

scientific article published on 01 August 1988

Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptors

scientific article published on 01 April 1993

Endothelin-1 and angiotensin-II stimulate delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for common signaling mechanisms

scientific article published on 01 February 1994

Enhancement of kinase selectivity in a potent class of arylamide FMS inhibitors

scientific article published in October 2013

Epidermal growth factor activates phosphoinositide turnover and protein kinase C in BALB/MK keratinocytes.

scientific article

Expression of protein kinase CI in NIH 3T3 cells increases its growth response to specific activators.

scientific article published on January 1990

JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia.

scientific article

Molecular characterization of angiotensin II type II receptors in rat pheochromocytoma cells

scientific article published on May 1, 1992

Pharmacodynamics and pharmacokinetics of the novel thrombopoietin mimetic peptide RWJ-800088 in humans.

scientific article

Pharmacokinetic and pharmacodynamic modeling of pegylated thrombopoietin mimetic peptide (PEG-TPOm) after single intravenous dose administration in healthy subjects

scientific article

Reducing ion channel activity in a series of 4-heterocyclic arylamide FMS inhibitors

scientific article published on 12 May 2010

Structure-based design, synthesis and SAR of a novel series of thiopheneamidine urokinase plasminogen activator inhibitors.

scientific article published in June 2001

Structure-based optimization of a potent class of arylamide FMS inhibitors

scientific article published on 26 April 2008

Synthesis and evaluation of novel 3,4,6-substituted 2-quinolones as FMS kinase inhibitors

scientific article

Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors.

scientific article published in April 2001

The discovery of novel cyclohexylamide CCR2 antagonists

scientific article published on 08 October 2011

List of works by Christopher J. Molloy

A functional radioreceptor assay of alpha-V-beta-3 (alphavbeta3) inhibitors in plasma: application as an ex vivo pharmacodynamic model

A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s.

Activin A and TGF-beta stimulate phosphorylation of focal adhesion proteins and cytoskeletal reorganization in rat aortic smooth muscle cells

Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s.

Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor

Design and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s

Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.

Discovery of novel FMS kinase inhibitors as anti-inflammatory agents

Effect of retinoid deficiency on keratin expression in mouse bladder

Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptors

Endothelin-1 and angiotensin-II stimulate delayed mitogenesis in cultured rat aortic smooth muscle cells: evidence for common signaling mechanisms

Enhancement of kinase selectivity in a potent class of arylamide FMS inhibitors

Epidermal growth factor activates phosphoinositide turnover and protein kinase C in BALB/MK keratinocytes.

Expression of protein kinase CI in NIH 3T3 cells increases its growth response to specific activators.

JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia.

Molecular characterization of angiotensin II type II receptors in rat pheochromocytoma cells

Pharmacodynamics and pharmacokinetics of the novel thrombopoietin mimetic peptide RWJ-800088 in humans.

Pharmacokinetic and pharmacodynamic modeling of pegylated thrombopoietin mimetic peptide (PEG-TPOm) after single intravenous dose administration in healthy subjects

Reducing ion channel activity in a series of 4-heterocyclic arylamide FMS inhibitors

Structure-based design, synthesis and SAR of a novel series of thiopheneamidine urokinase plasminogen activator inhibitors.

Structure-based optimization of a potent class of arylamide FMS inhibitors

Synthesis and evaluation of novel 3,4,6-substituted 2-quinolones as FMS kinase inhibitors

Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors.

The discovery of novel cyclohexylamide CCR2 antagonists