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List of works by Michelle P. McIntosh

A comparison of the lung clearance kinetics of Solid lipid nanoparticles and Liposomes by following the 3H-labelled structural lipids after pulmonary delivery in rats.

scientific article published on 5 January 2018

A simple and efficient high-performance liquid chromatographic assay for etomidate in plasma.

scientific article

Assessing the operational feasibility and acceptability of an inhalable formulation of oxytocin for improving community-based prevention of postpartum haemorrhage in Myanmar: a qualitative inquiry

scientific article

Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing of Pseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance.

scientific article published on 26 April 2016

Comb Poly(Oligo(2-Ethyl-2-Oxazoline)Methacrylate)-Peptide Conjugates Prepared by Aqueous Cu(0)-Mediated Polymerization and Reductive Amination

scientific article published on 17 November 2016

Comparative canine pharmacokinetics-pharmacodynamics of fospropofol disodium injection, propofol emulsion, and cyclodextrin-enabled propofol solution following bolus parenteral administration

scientific article

Desbutylhalofantrine: evaluation of QT prolongation and other cardiovascular effects after intravenous administration in vivo.

scientific article published in March 2003

Differences in the lipoprotein binding profile of halofantrine in fed and fasted human or beagle plasma are dictated by the respective masses of core apolar lipoprotein lipid

scientific article

Disposition and safety of inhaled biodegradable nanomedicines: Opportunities and challenges

scientific article published on 23 March 2016

Effect of Freezing on Oxytocin Ampules

scientific article published on 01 May 2013

Effect of increased surface hydrophobicity via drug conjugation on the clearance of inhaled PEGylated polylysine dendrimers.

scientific article published on 13 July 2017

Effective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization

scientific article

Elucidation of the pharmacokinetic/pharmacodynamic determinants of fosfomycin activity against Pseudomonas aeruginosa using a dynamic in vitro model.

scientific article

Evaluation of mean arterial blood pressure, heart rate, and sympathetic nerve activity in rabbits after administration of two formulations of etomidate

scientific article published in May 2007

Evaluation of the Impact of Sulfobutylether7-β-Cydodextrin on the Liquid Chromatography-Mass spectrometry Analysis of Biological Samples Arising from In Vivo Pharmacokinetic Studies

scientific article published on 12 January 2015

Evaluation of the impact of altered lipoprotein binding conditions on halofantrine induced QTc interval prolongation in an anaesthetized rabbit model

scientific article published in January 2004

Hemodynamic profile in rabbits of fospropofol disodium injection relative to propofol emulsion following rapid bolus injection

scientific article

Impact of Chlorpromazine Self-Association on Its Apparent Binding Constants With Cyclodextrins: Effect of SBE7-β-CD on the Disposition of Chlorpromazine in the Rat

scientific article published on 01 July 2010

In Situ Conjugation of Dithiophenol Maleimide Polymers and Oxytocin for Stable and Reversible Polymer–Peptide Conjugates

scientific article published on 10 March 2015

In vitro and in vivo evaluation of a sulfobutyl ether beta-cyclodextrin enabled etomidate formulation

scientific article published in October 2004

In vitro pharmacodynamics of fosfomycin against clinical isolates of Pseudomonas aeruginosa.

scientific article published on 24 July 2015

Influence of physicochemical properties on the patterns of association of a series of aliphatic esters of halofantrine with plasma lipoproteins

scientific article published in March 2004

Investigating the interactions of amino acid components on a mannitol-based spray-dried powder formulation for pulmonary delivery: A design of experiment approach

scientific article published on 21 September 2011

Knowledge, perception and practice towards oxytocin stability and quality: A qualitative study of stakeholders in three resource-limited countries

scientific article published in PLoS ONE

Lipid digestion as a trigger for supersaturation: evaluation of the impact of supersaturation stabilization on the in vitro and in vivo performance of self-emulsifying drug delivery systems.

scientific article published on 15 June 2012

Local inflammation alters the lung disposition of a drug loaded pegylated liposome after pulmonary dosing to rats

scientific article published on 29 May 2019

Miniature inhalation therapy platform using surface acoustic wave microfluidic atomization.

scientific article published on 14 May 2009

New developments in dry powder pulmonary vaccine delivery.

scientific article published on 20 January 2011

Ongoing in vivo studies with cytoskeletal drugs in tau transgenic mice.

scientific article published on July 2006

Ontogeny of the adrenal gland in the spiny mouse, with particular reference to production of the steroids cortisol and dehydroepiandrosterone.

scientific article published on 25 January 2013

PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin

scientific article published on 13 August 2013

Population pharmacokinetics of colistin methanesulfonate in rats: achieving sustained lung concentrations of colistin for targeting respiratory infections.

scientific article published on 5 August 2013

Preclinical comparison of intravenous melphalan pharmacokinetics administered in formulations containing either (SBE)7 m-β-cyclodextrin or a co-solvent system.

scientific article published on November 2010

Preliminary evaluation of polymer-based drug composite microparticle production by coacervate desolvation with supercritical carbon dioxide

scientific article published in March 2006

Probing a Potential In Vivo Drug–Excipient Interaction: Temporal Effects of a Modified β-Cyclodextrin on the Intravenous Pharmacokinetics of a Model High-Affinity Drug Ligand

scientific article published on 01 May 2012

Pulmonary administration of PEGylated polylysine dendrimers: absorption from the lung versus retention within the lung is highly size-dependent

scientific article published on 26 June 2013

Pulmonary and systemic pharmacokinetics of inhaled and intravenous colistin methanesulfonate in cystic fibrosis patients: targeting advantage of inhalational administration.

scientific article published on 18 February 2014

Pulmonary delivery of an ultra-fine oxytocin dry powder formulation: potential for treatment of postpartum haemorrhage in developing countries

scientific article (publication date: 2013)

Qualitative formative implementation research to inform introduction of a new essential medicine

scientific article published on 20 July 2019

Quality of oxytocin ampoules available in health care facilities in the Democratic Republic of Congo: an exploratory study in five provinces

article

Removal of interstitial hyaluronan with recombinant human hyaluronidase improves the systemic and lymphatic uptake of cetuximab in rats

scientific article published on 23 October 2019

Safety, Tolerability and Pharmacokinetics of Single Doses of Oxytocin Administered via an Inhaled Route in Healthy Females: Randomized, Single-blind, Phase 1 Study

scientific article published on 22 July 2017

Single quadrupole mass spectrometry for pre-clinical pharmacokinetic analysis: Quantitation of carvedilol in dog plasma

scientific article published on 20 February 2007

Spray-Dried Influenza Antigen with Trehalose and Leucine Produces an Aerosolizable Powder Vaccine Formulation that Induces Strong Systemic and Mucosal Immunity after Pulmonary Administration

scientific article published on 25 February 2015

Stability Enhancing N-Terminal PEGylation of Oxytocin Exploiting Different Polymer Architectures and Conjugation Approaches.

scientific article published on 15 July 2016

Structural influence of cohesive mixtures of salbutamol sulphate and lactose on aerosolisation and de-agglomeration behaviour under dynamic conditions

scientific article

Substantial Targeting Advantage Achieved by Pulmonary Administration of Colistin Methanesulfonate in a Large-Animal Model.

scientific article

Suggested Procedures for the Reproducible Synthesis of Poly(d,l-lactide-co-glycolide) Nanoparticles Using the Emulsification Solvent Diffusion Platform

scientific article published on 01 October 2018

Temperature stability of oxytocin ampoules labelled for storage at 2°C-8°C and below 25°C: an observational assessment under controlled accelerated and temperature cycling conditions

scientific article published on 26 July 2019

The Effect of Intravenous Sulfobutylether7-β-Cyclodextrin on the Pharmacokinetics of a Series of Adamantane-Containing Compounds

scientific article published on 08 January 2015

The Lymphatic System Plays a Major Role in the Intravenous and Subcutaneous Pharmacokinetics of Trastuzumab in Rats

scientific article published on 09 January 2014

The Role of the Intestinal Lymphatics in the Absorption of Two Highly Lipophilic Cholesterol Ester Transfer Protein Inhibitors (CP524,515 and CP532,623)

scientific article published on 11 March 2010

The effect of amino acid excipients on morphology and solid-state properties of multi-component spray-dried formulations for pulmonary delivery of biomacromolecules

scientific article

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