Search filters

List of works by Leslie Crews

ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia.

scientific article published on 28 December 2012

Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice.

scientific article published on April 2008

Amelioration of the cerebrovascular amyloidosis in a transgenic model of Alzheimer's disease with the neurotrophic compound cerebrolysin

scientific article published on 7 July 2004

Astroglial activation of extracellular-regulated kinase in early stages of Alzheimer disease

scientific article

Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

scientific article

Chronic myeloid leukemia stem cell biology.

scientific article published on June 2012

Climbing the scaffolds of Parkinson's disease pathogenesis

scientific article

Clinical utility of objective tests for dry eye disease: variability over time and implications for clinical trials and disease management

scientific article published on 01 September 2012

Cognitive deficits and degeneration of interneurons in HIV+ methamphetamine users

scientific article published in October 2006

Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications ⬇️

scientific article published on December 28, 2012

Corrigendum to “Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis”

article

Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology

scientific article

Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study

scientific article published on 01 May 2012

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

scientific article published in June 2005

High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease

scientific article published on 15 July 2005

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

scientific article

Increased CDK5 Expression in HIV Encephalitis Contributes to Neurodegeneration via Tau Phosphorylation and Is Reversed with Roscovitine ⬇️

scientific article published on April 1, 2011

Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice

scientific article on November 2008

Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases

scientific article

Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease. ⬇️

scientific article

Molecular mechanisms of neurodegeneration in Alzheimer's disease

scientific article

Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux

scientific article

NOTCH1 Signaling Promotes Human T-Cell Acute Lymphoblastic Leukemia Initiating Cell Regeneration in Supportive Niches ⬇️

scientific article published on June 29, 2012

Neurological and neurodegenerative alterations in a transgenic mouse model expressing human alpha-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.

scientific article published on November 2005

Neuronal injury in simian immunodeficiency virus and other animal models of neuroAIDS.

scientific article published on August 2008

Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation.

scientific article published in February 2007

Neurotoxic effects of the HCV core protein are mediated by sustained activation of ERK via TLR2 signaling

scientific article published on 10 June 2011

Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease

scientific article (publication date: 29 April 2011)

Pathogenesis of hepatitis C virus coinfection in the brains of patients infected with HIV.

scientific article published on 15 June 2007

Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis

scientific article published in December 2004

Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders ⬇️

scientific article published on September 24, 2011

Regional Comparison of the Neurogenic Effects of CNTF-Derived Peptides and Cerebrolysin in AβPP Transgenic Mice ⬇️

scientific article published on January 1, 2011

Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases ⬇️

scientific article published on January 1, 2003

Role of α‐synuclein penetration into the membrane in the mechanisms of oligomer pore formation ⬇️

scientific article published on February 27, 2012

Selective elimination of leukemia stem cells: hitting a moving target

scientific article published on 17 August 2012

Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy

scientific article

Toll-like receptor pathway gene expression is associated with human immunodeficiency virus-associated neurodegeneration

scientific article published in December 2007

α-Synuclein induces alterations in adult neurogenesis in Parkinson disease models via p53-mediated repression of Notch1.

scientific article

Paulina is supported by:

About Paulina

Help