List of works - Toru Sengoku

A SelB/EF-Tu/aIF2γ-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).

scientific article

A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase

scientific article

Characterization and Structure of the Aquifex aeolicus Protein DUF752: A BACTERIAL tRNA-METHYLTRANSFERASE (MnmC2) FUNCTIONING WITHOUT THE USUALLY FUSED OXIDASE DOMAIN (MnmC1)

scientific article

Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A

scientific article

Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus

scientific article

Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli

scientific article

Crystallization and preliminary X-ray analysis of the helicase domains of Vasa complexed with RNA and an ATP analogue

scientific article published on 23 January 2004

Development and Structural Evaluation of N-Alkylated trans-2-Phenylcyclopropylamine-Based LSD1 Inhibitors

scientific article published on 12 March 2020

Genetic landscape of Rett syndrome-like phenotypes revealed by whole exome sequencing

scientific article published on 06 March 2019

OTUD5 Variants Associated With X-Linked Intellectual Disability and Congenital Malformation

scientific article published on 03 March 2021

Phenotype-genotype correlations in patients with GNB1 gene variants, including the first three reported Japanese patients to exhibit spastic diplegia, dyskinetic quadriplegia, and infantile spasms

scientific article published on 15 November 2019

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53

scientific article

Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase

scholarly article

Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa

scientific article (publication date: 21 April 2006)

Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A

scientific article

Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP.

scientific article published on 13 February 2018

Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2

scientific article published on 15 November 2021

Substrate tRNA Recognition Mechanism of a Multisite-specific tRNA Methyltransferase, Aquifex aeolicus Trm1, Based on the X-ray Crystal Structure

scientific article

Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder

scientific article published on 18 June 2021

The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype

scientific article published on 24 December 2019

Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity.

scientific article published on 17 April 2018

UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development

scientific article

List of works by Toru Sengoku

A SelB/EF-Tu/aIF2γ-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).

A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase

Characterization and Structure of the Aquifex aeolicus Protein DUF752: A BACTERIAL tRNA-METHYLTRANSFERASE (MnmC2) FUNCTIONING WITHOUT THE USUALLY FUSED OXIDASE DOMAIN (MnmC1)

Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A

Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus

Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli

Crystallization and preliminary X-ray analysis of the helicase domains of Vasa complexed with RNA and an ATP analogue

Development and Structural Evaluation of N-Alkylated trans-2-Phenylcyclopropylamine-Based LSD1 Inhibitors

Genetic landscape of Rett syndrome-like phenotypes revealed by whole exome sequencing

OTUD5 Variants Associated With X-Linked Intellectual Disability and Congenital Malformation

Phenotype-genotype correlations in patients with GNB1 gene variants, including the first three reported Japanese patients to exhibit spastic diplegia, dyskinetic quadriplegia, and infantile spasms

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53

Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase

Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa

Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A

Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP.

Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2

Substrate tRNA Recognition Mechanism of a Multisite-specific tRNA Methyltransferase, Aquifex aeolicus Trm1, Based on the X-ray Crystal Structure

Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder

The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype

Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity.

UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development