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List of works by Max J Cryle

A facile Fmoc solid phase synthesis strategy to access epimerization-prone biosynthetic intermediates of glycopeptide antibiotics

scientific article published on 14 April 2014

A proof-reading mechanism for non-proteinogenic amino acid incorporation into glycopeptide antibiotics

scientific article published on 29 August 2019

A route to diastereomerically pure phenylglycine thioester peptides: crucial intermediates for investigating glycopeptide antibiotic biosynthesis

scientific article published on 9 February 2018

Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation

scientific article published on 18 November 2019

Antibiotic-chemoattractants enhance neutrophil clearance of Staphylococcus aureus

scientific article published on 25 October 2021

Arachidonic acid potentiates exocytosis and allows neuronal SNARE complex to interact with Munc18a

scientific article published on 23 December 2006

Are branched chain fatty acids the natural substrates for P450(BM3)?

scientific article published on 30 March 2006

Biological, chemical, and biochemical strategies for modifying glycopeptide antibiotics

scientific article published on 31 October 2019

Carbon-carbon bond cleavage by cytochrome p450(BioI)(CYP107H1).

scientific article

Carrier protein substrates in cytochrome P450-catalysed oxidation.

scientific article published on 18 January 2011

Catalytic promiscuity of glycopeptide N-methyltransferases enables bio-orthogonal labelling of biosynthetic intermediates.

scientific article published on 4 November 2016

Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria

scientific article published on 19 May 2020

Chlorinated Glycopeptide Antibiotic Peptide Precursors Improve Cytochrome P450-Catalyzed Cyclization Cascade Efficiency

scientific article published on 20 February 2017

Crystal structure and mechanism of a DNA (6-4) photolyase

scientific article

Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1

scientific article

Cyclopropyl containing fatty acids as mechanistic probes for cytochromes P450.

scientific article published in April 2005

Cyclopropyl fatty acids implicate a radical but not a cation as an intermediate in P450BM3-catalysed hydroxylations

scientific article published on 27 January 2004

Cytochrome P450 OxyBtei catalyzes the first phenolic coupling step in teicoplanin biosynthesis

scientific article

Cytochrome p450sky interacts directly with the nonribosomal peptide synthetase to generate three amino acid precursors in skyllamycin biosynthesis

scientific article

Diversity of nature's assembly lines - recent discoveries in non-ribosomal peptide synthesis.

scientific article published on 17 November 2016

Drosophila melanogaster nonribosomal peptide synthetase Ebony encodes an atypical condensation domain

scientific article published on 31 January 2019

Enzymatic Cascade To Evaluate the Tricyclization of Glycopeptide Antibiotic Precursor Peptides as a Prequel to Biosynthetic Redesign

scientific article published on 11 October 2019

Enzyme-substrate complementarity governs access to a cationic reaction manifold in the P450(BM3)-catalysed oxidation of cyclopropyl fatty acids

scientific article published on 29 October 2012

Exploring the Tetracyclization of Teicoplanin Precursor Peptides through Chemoenzymatic Synthesis

scientific article published on 11 December 2019

Femtosecond free-electron laser x-ray diffraction data sets for algorithm development

scientific article

Functional expression and characterization of cytochrome P450 52A21 from Candida albicans

scientific journal article

Halogenation of glycopeptide antibiotics occurs at the amino acid level during non-ribosomal peptide synthesis

scientific article

Is the ferric hydroperoxy species responsible for sulfur oxidation in cytochrome p450s?

scientific article published on 01 December 2006

Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics

scientific article published on 13 June 2019

More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH

scientific article

New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis

scientific article

Online Pyrophosphate Assay for Analyzing Adenylation Domains of Nonribosomal Peptide Synthetases

scientific article published on 11 January 2016

Precursor Manipulation in Glycopeptide Antibiotic Biosynthesis: Are β-Amino Acids Compatible with the Oxidative Cyclization Cascade?

scientific article published on 30 April 2018

Products of cytochrome P450(BioI) (CYP107H1)-catalyzed oxidation of fatty acids

scientific article published on 01 September 2003

Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics.

scientific article published on February 2015

SNaPe: a versatile method to generate multiplexed protein fusions using synthetic linker peptides for in vitro applications.

scientific article

Selectivity in a barren landscape: the P450(BioI)-ACP complex.

scientific article published on August 2010

Structural Characterization of OxyD, a Cytochrome P450 Involved in  -Hydroxytyrosine Formation in Vancomycin Biosynthesis

scientific article

Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase

scientific article

Structural aspects of phenylglycines, their biosynthesis and occurrence in peptide natural products.

scientific article published on July 2015

Structural characterization of CYP165D3, a cytochrome P450 involved in phenolic coupling in teicoplanin biosynthesis ⬇️

scientific article published on October 23, 2010

Structure of OxyA tei: completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascade

scientific article

Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis

scientific article

Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity

scientific article published on 04 May 2021

The Diiron Monooxygenase CmlA from Chloramphenicol Biosynthesis Allows Reconstitution of β-Hydroxylation during Glycopeptide Antibiotic Biosynthesis

scientific article published on 10 December 2019

The Thioesterase Domain in Glycopeptide Antibiotic Biosynthesis Is Selective for Cross-Linked Aglycones

scientific article published in December 2017

The archaeal cofactor F 0 is a light-harvesting antenna chromophore in eukaryotes

scientific article

The biosynthetic implications of late-stage condensation domain selectivity during glycopeptide antibiotic biosynthesis

scientific article published on 10 October 2018

The crystal structure of the versatile cytochrome P450 enzyme CYP109B1 from Bacillus subtilis

scientific article

The many faces and important roles of protein-protein interactions during non-ribosomal peptide synthesis

scientific article published on 01 November 2018

The role of the conserved threonine in P450 BM3 oxygen activation: substrate-determined hydroxylation activity of the Thr268Ala mutant

scientific article published in January 2008

The structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenase

scientific article

Two uptake hydrogenases differentially interact with the aerobic respiratory chain during mycobacterial growth and persistence

scientific article published on 17 October 2019

Ultrafast Charge Rearrangement and Nuclear Dynamics upon Inner-Shell Multiple Ionization of Small Polyatomic Molecules

scientific article published in Physical Review Letters

Understanding biosynthetic protein-protein interactions

scientific article published on 01 November 2018

Understanding the crucial interactions between Cytochrome P450s and non-ribosomal peptide synthetases during glycopeptide antibiotic biosynthesis

scientific article

Unrivalled diversity: the many roles and reactions of bacterial cytochromes P450 in secondary metabolism

scientific article published on 01 August 2018

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis

scientific article

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