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List of works by Darryl R. Overby

A model of giant vacuole dynamics in human Schlemm's canal endothelial cells.

scientific article

A model of the oscillatory mechanical forces in the conventional outflow pathway

scientific article published on 01 January 2019

A new method for selection of angular aqueous plexus cells from porcine eyes: a model for Schlemm's canal endothelium

scientific article

A new view of the human trabecular meshwork using quick-freeze, deep-etch electron microscopy.

scientific article

Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma

scientific article

Animal models of glucocorticoid-induced glaucoma

scientific article

Biomechanical strain as a trigger for pore formation in Schlemm's canal endothelial cells

scientific article

Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction

scientific article published on 16 September 2014

Bisphenol A Induces Fatty Liver by an Endocannabinoid-Mediated Positive Feedback Loop.

scientific article published on 25 March 2016

Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels

scientific article published in February 2006

Colocalization of outflow segmentation and pores along the inner wall of Schlemm's canal

scientific article

Concentration-related effects of nitric oxide and endothelin-1 on human trabecular meshwork cell contractility

scientific article published on 27 December 2013

Consensus recommendations for trabecular meshwork cell isolation, characterization and culture

scientific article published on 9 March 2018

Detection of proteoglycan loss from articular cartilage using Brillouin microscopy, with applications to osteoarthritis

scientific article published on 17 April 2019

Direct measurement of pressure-independent aqueous humour flow using iPerfusion

scientific article published on 16 July 2017

Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents.

scientific article

Effect of phacoemulsification on facility of outflow

scientific article published on 13 April 2018

Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm's Canal Endothelia

scientific article published on 16 January 2017

In vitro models for glaucoma research: effects of hydrostatic pressure.

scientific article published on 11 August 2011

Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration

scientific article published in March 2017

Localized and Controlled Delivery of Nitric Oxide to the Conventional Outflow Pathway via Enzyme Biocatalysis: Toward Therapy for Glaucoma

scientific article

Magnetic Cellular Switches

scientific article published on January 1, 2004

Measurement of Outflow Facility Using iPerfusion

scientific article

Mechanical properties of individual focal adhesions probed with a magnetic microneedle

scientific article published in January 2004

Multi-scale analysis of segmental outflow patterns in human trabecular meshwork with changing intraocular pressure

scientific article published on 23 January 2014

Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry

scientific article published on 31 March 2005

Outflow Physiology of the Mouse Eye: Pressure Dependence and Washout

scientific article published on March 29, 2011

PHARMACOLOGICAL REGULATION OF OUTFLOW RESISTANCE DISTAL TO SCHLEMM'S CANAL.

scientific article published on 6 April 2018

Peptide-Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite-Mediated Nitration.

scientific article published on 17 May 2017

Pharmacologic manipulation of conventional outflow facility in ex vivo mouse eyes

scientific article

Physical Factors Affecting Outflow Facility Measurements in Mice.

scientific article

Pilocarpine-induced dilation of Schlemm's canal and prevention of lumen collapse at elevated intraocular pressures in living mice visualized by OCT.

scientific article

Quantification of Scleral Biomechanics and Collagen Fiber Alignment.

scientific article published in January 2018

Reduced humidity experienced by mice in vivo coincides with reduced outflow facility measured ex vivo

scientific article published on 24 July 2019

Reduction of the available area for aqueous humor outflow and increase in meshwork herniations into collector channels following acute IOP elevation in bovine eyes.

scientific article published on 30 May 2008

Role of nitric oxide in murine conventional outflow physiology

scientific article

Shear Stress in Schlemm's Canal as a Sensor of Intraocular Pressure

scientific article published on 02 April 2020

Shear stress-triggered nitric oxide release from Schlemm's canal cells

scientific article

Specific Hydraulic Conductivity of Corneal Stroma as Seen by Quick-Freeze/Deep-Etch

scientific article published on 01 April 2001

Stimulation of chondrogenic differentiation of adult human bone marrow-derived stromal cells by a moderate-strength static magnetic field.

scientific article

Structural basement membrane components and corresponding integrins in Schlemm's canal endothelia

scientific article published on January 19, 2011

Studies on depth-of-field effects in microscopy supported by numerical simulations

scientific article published in December 2005

The Value of Mouse Models for Glaucoma Drug Discovery

scientific article published on 16 March 2016

The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium.

scientific article published on 11 December 2008

The design and development of a high-throughput magneto-mechanostimulation device for cartilage tissue engineering.

scientific article published on 18 July 2013

The influence of genetic background on conventional outflow facility in mice.

scientific article published on 19 December 2013

The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes.

scientific article published on 5 November 2007

The mechanism of increasing outflow facility during washout in the bovine eye.

scientific article

The structure of the trabecular meshwork, its connections to the ciliary muscle, and the effect of pilocarpine on outflow facility in mice.

scientific article

Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma.

scientific article

Tools to study cell mechanics and mechanotransduction

scientific article published in January 2007

Transport across Schlemm's canal endothelium and the blood-aqueous barrier.

scientific article published on 12 December 2015

Ultrastructural changes associated with dexamethasone-induced ocular hypertension in mice.

scientific article

Unconventional aqueous humor outflow: A review

scientific article published on 2 February 2016

VEGF as a Paracrine Regulator of Conventional Outflow Facility

scientific article published on March 2017

Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes.

scientific article published on 13 April 2016

Water content, not stiffness, dominates Brillouin spectroscopy measurements in hydrated materials

scientific article published on 01 August 2018

eNOS, a pressure-dependent regulator of intraocular pressure.

scientific article published on 9 December 2011