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List of works by Dean R. Tolan

A lysine to arginine substitution at position 146 of rabbit aldolase A changes the rate-determining step to Schiff base formation.

scientific article published in January 1996

A partially active mutant aldolase B from a patient with hereditary fructose intolerance

scientific article

A rabbit AldA pseudogene derived from a partially spliced primary aldolase A transcript.

scientific article published on October 1992

Actin Filament- and Wiskott-Aldrich Syndrome Protein-Binding Sites on Fructose-1,6-bisphosphate Aldolase are Functionally Distinct from the Active Site

scientific article published on 18 November 2020

Aldolase A Ins(1,4,5)P3-binding domains as determined by site-directed mutagenesis

scientific article

Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans

scientific journal article

Aldolases a and C are ribonucleolytic components of a neuronal complex that regulates the stability of the light-neurofilament mRNA.

scientific article published in April 2005

Alternative splicing of fructose 1,6-bisphosphate aldolase transcripts in Drosophila melanogaster predicts three isozymes

scientific article published in February 1992

Aminoethylation in model peptides reveals conditions for maximizing thiol specificity

scientific article

Antisense inhibition of R-cognin expression modulates differentiation of retinal neurons in vitro

scientific article published on November 21, 1997

Association of the widespread A149P hereditary fructose intolerance mutation with newly identified sequence polymorphisms in the aldolase B gene

scientific article

Catalytic deficiency of human aldolase B in hereditary fructose intolerance caused by a common missense mutation

scientific article

Characterization of recombinant human aldolase B and purification by metal chelate chromatography

scientific article published on 01 January 1995

Characterization of the human aldolase B gene

scientific article

Chemical-modification rescue assessed by mass spectrometry demonstrates that gamma-thia-lysine yields the same activity as lysine in aldolase

scientific article published on July 2002

Complete amino acid sequence for human aldolase B derived from cDNA and genomic clones

scientific article

Construction of a high-copy "ATG vector" for expression in Escherichia coli.

scientific article

Crosslinking of eukaryotic initiation factor eIF3 to the 40S ribosomal subunit from rabbit reticulocytes

scientific article published on 01 July 1983

Developmental localization of retina cognin synthesis by in situ hybridization

scientific article published in December 1997

Differential usage of the carboxyl-terminal region among aldolase isozymes.

scientific article published in May 1993

Disruption of the aldolase A tetramer into catalytically active monomers

scientific article published on May 1996

Evolutionary implications of the human aldolase-A, -B, -C, and -pseudogene chromosome locations

scientific article

Expression of aldolase A steady-state mRNA is delayed relative to other muscle-specific genes during differentiation of chicken myoblasts

scientific article published in September 1995

Genes required for fructose metabolism are expressed in Purkinje cells in the cerebellum

scientific article published on 2 November 2005

Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease.

scientific article published in June 1991

Identification of Neuronal Isozyme Specific Residues by Comparison of Goldfish Aldolase C to Other Aldolases ⬇️

scientific article published on August 1, 1997

Identification of a splice-site mutation in the aldolase B gene from an individual with hereditary fructose intolerance

scientific article

Identification of conserved promoter elements for aldB and isozyme specific residues in aldolase B.

scientific article published in January 1999

Intein-mediated purification of a recombinantly expressed peptide

scientific article published on 23 September 2004

Intraneuronal Abeta42 accumulation in Down syndrome brain

scientific article published in June 2002

Lysine-146 of rabbit muscle aldolase is essential for cleavage and condensation of the C3-C4 bond of fructose 1,6-bis(phosphate)

scientific article published on 01 October 1994

Metabolic Compartmentation in Living Cells: Structural Association of Aldolase ⬇️

scientific article published on December 15, 1997

Molecular analysis of aldolase B genes in hereditary fructose intolerance

scientific article

Molecular analysis of common aldolase B alleles for hereditary fructose intolerance in North Americans

scientific article published on 01 August 1992

Molecular evidence for compound heterozygosity in hereditary fructose intolerance

scientific article

Mutations in the promoter region of the aldolase B gene that cause hereditary fructose intolerance.

scientific article

New superfamily members identified for Schiff-base enzymes based on verification of catalytically essential residues.

scientific article

Noncoordinate changes in the steady-state mRNA expressed from aldolase A and aldolase C genes during differentiation of chicken myoblasts

scientific article published in March 1995

Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton.

scientific article published on January 2016

Presteady-state kinetic evidence for a ring-opening activity in fructose-1,6-(bis)phosphate aldolase

scientific article published in March 2004

Protein topography of the 40 S ribosomal subunit from rabbit reticulocytes shown by cross-linking with 2-iminothiolane

scientific article published on 01 October 1981

Quantitative gene expression profiles in real time from expressed sequence tag databases

scientific article

Radioiodination of microgram quantities of ribosomal proteins from polyacrylamide gels

scientific article published on 01 March 1980

Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease

scientific article published on 12 November 2019

Recombinant anaerobic maize aldolase: overexpression, characterization, and metabolic implications.

scientific article

Recommendations for locus-specific databases and their curation

scientific article

Role of fructose and fructokinase in acute dehydration-induced vasopressin gene expression and secretion in mice

scientific article published on 16 November 2016

Site-directed mutagenesis identifies aspartate 33 as a previously unidentified critical residue in the catalytic mechanism of rabbit aldolase A.

scientific article

Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose-1,6-bisphosphate aldolase

scientific article (publication date: 9 May 2003)

Specific regions of the brain are capable of fructose metabolism

scientific article published on 26 December 2016

Stabilization of the predominant disease-causing aldolase variant (A149P) with zwitterionic osmolytes

scientific article

Structure of a fructose-1,6-bis(phosphate) aldolase liganded to its natural substrate in a cleavage-defective mutant at 2.3 A(,)

scientific article

Structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant

scientific article

Subunit interface mutants of rabbit muscle aldolase form active dimers

scientific article

Targeting of Several Glycolytic Enzymes Using RNA Interference Reveals Aldolase Affects Cancer Cell Proliferation through a Non-glycolytic Mechanism ⬇️

scientific article published on October 23, 2012

The complete amino Acid sequence for the anaerobically induced aldolase from maize derived from cDNA clones.

scientific article published in December 1986

The complete amino acid sequence of the human aldolase C isozyme derived from genomic clones

scientific article

The complete nucleotide sequence for rabbit muscle aldolase A messenger RNA.

scientific article published in January 1984

The hisT-purF region of the Escherichia coli K-12 chromosome. Identification of additional genes of the hisT and purF operons

scientific article published in September 1987

The purification and characterization of multiple forms of protein synthesis eukaryotic initiation factors 2, 3, and 5 from rabbit reticulocytes

scientific article published on 01 January 1981

The structure of human liver fructose-1,6-bisphosphate aldolase

scientific article

The temperature dependence of activity and structure for the most prevalent mutant aldolase B associated with hereditary fructose intolerance

scientific article published in December 2002

Thermodynamic analysis of the dissociation of the aldolase tetramer substituted at one or both of the subunit interfaces

scientific article published in October 2003

Unique use of alternative polyadenylation signals in the mouse aldolase B gene

scientific article

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