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List of works by Ewa Chojnacka-Wójcik

1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics

scientific article

Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice.

scientific article published on 7 May 2006

Antidepressant-like effect of the selective 5-HT1B receptor agonist CP 94253: a possible mechanism of action

scientific article

Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1-aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats.

scientific article published in November 2002

Anxiolytic-like action of MTEP expressed in the conflict drinking Vogel test in rats is serotonin dependent.

scientific article

Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent

scientific article published on 3 October 2006

Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABA(A) signaling

scientific article

Anxiolytic-like effects of group III mGlu receptor ligands in the hippocampus involve GABAA signaling

scientific article

Conformational restriction in novel NAN-190 and MP3022 analogs and their 5-HT(1A) receptor activity

scientific article published on 01 September 2006

Corrigendum to “Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor antagonist does not involve GABAA signaling” [Neuropharmacology 47 (2004) 342–350]

scholarly article published in Neuropharmacology

Effect of combined administration of 5-HT1A or 5-HT1B/1D receptor antagonists and antidepressants in the forced swimming test

scientific article published in March 2004

Effects of GABAB receptor ligands in rodent tests of anxiety-like behavior

scientific article

Effects of combined administration of 5-HT1A and/or 5-HT1B receptor antagonists and paroxetine or fluoxetine in the forced swimming test in rats.

scientific article published on November 2002

Enhancement of the anti-immobility action of antidepressants by a selective 5-HT7 receptor antagonist in the forced swimming test in mice

scientific article published on 17 October 2006

Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats.

scientific article published in February 2004

In the amygdala anxiolytic action of mGlu5 receptors antagonist MPEP involves neuropeptide Y but not GABAA signaling

scientific article

Interaction of 1,2,4-substituted piperazines, new serotonin receptor ligands, with 5-HT1A and 5-HT2A receptors

scientific article

Intrinsic activity and comparative molecular dynamics of buspirone analogues at the 5-HT(1A) receptors.

scientific article

Involvement of presynaptic 5-HT(1A) and benzodiazepine receptors in the anticonflict activity of 5-HT(1A) receptor antagonists

scientific article

Lack of the antianxiety-like effect of (S)-3,4-DCPG, an mGlu8 receptor agonist, after central administration in rats

scientific article published in November 2005

Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats

scientific article

New 4-[omega-(diarylmethylamino)alkyl]- and 4-[omega-(diarylmethoxy)alkyl]-1-arylpiperazines as selective 5-HT1A/5-HT2A receptor ligands with differentiated in vivo activity.

scientific article published in November 2004

New 9- or 10-arylpiperazinoalkyl substituted pyrimido- or diazepino[2,1-f]purines with partial or full 5-HT1A agonistic activity

New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation

scientific article published in May 2004

Novel 4-alkyl-1-arylpiperazines and 1,2,3,4-tetrahydroisoquinolines containing diphenylmethylamino or diphenylmethoxy fragment with differentiated 5-HT1A/5-HT2A/D2 receptor activity

scientific article published in July 2003

Novel N-[omega-[4-(2-methoxyphenyl)piperazin-1-yl]-ethyl]pyrid-2(1H)-ones with diversified 5-HT1A receptor activity

scientific article published in November 2002

Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation

scientific article

Novel, flexible, and conformationally defined analogs of gepirone: synthesis and 5-HT1A, 5-HT2A, and D2 receptor activity.

scientific article published in February 2005

Pharmacological analysis of the hypothermic effects of NAN-190 and its analogs, postsynaptic 5-HT1A receptor antagonists, in mice

scientific article published in July 2002

Pharmacological characterization of MP349, a novel 5-HT1A-receptor antagonist with anxiolytic-like activity, in mice and rats

scientific article published on April 2003

Pharmacological properties and SAR of new 1,4-disubstituted piperazine derivatives with hypnotic-sedative activity

scientific article

Roles of group II metabotropic glutamate receptors in modulation of seizure activity

scientific article published in March 2000

Stimulation of group II metabotropic glutamate receptors or inhibition of group I ones exerts anxiolytic-like effects in rats

scientific article published in January 2000

Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.

scientific article published on 2 November 2005

Synthesis and 5-HT(1A), 5-HT(2A) receptor activity of new beta-tetralonohydantoins

scientific article published in August 2005

Synthesis and 5-HT1A/5-HT2A receptor activity of new N-[3-(4-phenylpiperazin-1-yl)-propyl] derivatives of 3-spiro-cyclohexanepyrrolidine-2,5-dione and 3-spiro-beta-tetralonepyrrolidine-2,5-dione

scientific article published on July 1, 2003

Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity

scientific article published on 6 December 2009

Synthesis and pharmacological evaluation of new arylpiperazines. 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-quinazolidin-4-one - a dual serotonin 5-HT(1A)/5-HT(2A) receptor ligand with an anxiolytic-like activity

scientific article published in December 2002

Synthesis and preliminary pharmacological evaluation of imidazo[2,1-f]purine-2,4-dione derivatives

scientific article

Synthesis, in vitro and in vivo 5-HT1A/5-HT2A serotonin receptor activity of new hybrid 1,2,3,4-tetrahydro-gamma-carbolines with 1-(2-methoxyphenyl)piperazine moiety.

scientific article

The antianxiety-like effects of antagonists of group I and agonists of group II and III metabotropic glutamate receptors after intrahippocampal administration

scientific article published in October 2001

The anxiolytic-like activity of AIDA (1-aminoindan-1,5-dicarboxylic acid), an mGLu 1 receptor antagonist.

scientific article published in March 2004

The anxiolytic-like effect of 5-HT1B receptor ligands in rats: a possible mechanism of action

scientific article

The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines

scientific article published on 22 August 2007

The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT(1A)/5-HT(2A) receptor activities of its 1-adamantoyloaminoalkyl derivatives

scientific article published in January 2002

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