List of works - Andrias O O'Reilly

A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation.

scientific article

Association of neonicotinoid insensitivity with a conserved residue in the loop d binding region of the tick nicotinic acetylcholine receptor

scientific article published in June 2012

Binding of the anticonvulsant drug lamotrigine and the neurotoxin batrachotoxin to voltage-gated sodium channels induces conformational changes associated with block and steady-state activation.

scientific article published on 12 November 2002

Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel

scientific article (publication date: 2012)

DIsulfide Mapping PLanner Software Tool

scientific article

Effects of deglycosylation of sodium channels on their structure and function.

scientific article published in January 2005

G219S mutagenesis as a means of stabilizing conformational flexibility in the bacterial sodium channel NaChBac.

scientific article

Investigation into the role of an extracellular loop in mediating proton-evoked inhibition of voltage-gated sodium channels.

scientific article published on 19 September 2017

Knockdown resistance to DDT and pyrethroids: from target-site mutations to molecular modelling.

scientific article published on November 2008

Modelling insecticide-binding sites in the voltage-gated sodium channel.

scientific article published on June 2006

Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine.

scientific article published on 20 August 2017

Predictive 3D modelling of the interactions of pyrethroids with the voltage-gated sodium channels of ticks and mites.

scientific article

Role of hydrophobic residues in the voltage sensors of the voltage-gated sodium channel

scientific article published on 15 March 2007

Sodium channelopathies and pain

scientific article published on 26 January 2010

Tetrameric bacterial sodium channels: characterization of structure, stability, and drug binding.

scientific article

The peptaibol antiamoebin as a model ion channel: similarities to bacterial potassium channels.

scientific article

Voltage-gated sodium channels as targets for pyrethroid insecticides

scientific article published on 9 January 2017

List of works by Andrias O O'Reilly

A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation.

Association of neonicotinoid insensitivity with a conserved residue in the loop d binding region of the tick nicotinic acetylcholine receptor

Binding of the anticonvulsant drug lamotrigine and the neurotoxin batrachotoxin to voltage-gated sodium channels induces conformational changes associated with block and steady-state activation.

Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel

DIsulfide Mapping PLanner Software Tool

Effects of deglycosylation of sodium channels on their structure and function.

G219S mutagenesis as a means of stabilizing conformational flexibility in the bacterial sodium channel NaChBac.

Investigation into the role of an extracellular loop in mediating proton-evoked inhibition of voltage-gated sodium channels.

Knockdown resistance to DDT and pyrethroids: from target-site mutations to molecular modelling.

Modelling insecticide-binding sites in the voltage-gated sodium channel.

Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine.

Predictive 3D modelling of the interactions of pyrethroids with the voltage-gated sodium channels of ticks and mites.

Role of hydrophobic residues in the voltage sensors of the voltage-gated sodium channel

Sodium channelopathies and pain

Tetrameric bacterial sodium channels: characterization of structure, stability, and drug binding.

The peptaibol antiamoebin as a model ion channel: similarities to bacterial potassium channels.

Voltage-gated sodium channels as targets for pyrethroid insecticides