List of works - Jocelyn Côté

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

scientific article published in Nature Communications

A novel function for the survival motoneuron protein as a translational regulator

scientific article published on 06 November 2012

A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy.

scientific article published on 9 December 2015

A protein-domain microarray identifies novel protein-protein interactions

scientific article

A proteomic analysis of arginine-methylated protein complexes

scientific article published on 7 October 2003

Aberrant Splicing of tau Pre-mRNA Caused by Intronic Mutations Associated with the Inherited Dementia Frontotemporal Dementia with Parkinsonism Linked to Chromosome 17.

scientific article published in July 2000

Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics

scientific article published on 10 April 2013

Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization.

scientific article published on 11 September 2007

Alternatively spliced protein arginine methyltransferase 1 isoform PRMT1v2 promotes the survival and invasiveness of breast cancer cells.

scientific article published on 27 November 2012

Arginine methyltransferases as novel therapeutic targets for breast cancer

scientific article

Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy.

scientific article published in December 2017

Converging pathways involving microRNA-206 and the RNA-binding protein KSRP control post-transcriptionally utrophin A expression in skeletal muscle.

scientific article published on 26 December 2013

Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.

scientific article published on 17 November 2015

HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects.

scientific article published on 18 November 2010

IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice.

scientific article published on August 2015

Identification of the PRMT1v1 and PRMT1v2 specific interactomes by quantitative mass spectrometry in breast cancer cells.

scientific article

In vivo NMDA receptor activation accelerates motor unit maturation, protects spinal motor neurons, and enhances SMN2 gene expression in severe spinal muscular atrophy mice.

scientific article published on August 2010

KH-type splicing regulatory protein interacts with survival motor neuron protein and is misregulated in spinal muscular atrophy.

scientific article

Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae.

scientific article published on 23 February 2017

Misregulation of calcium-handling proteins promotes hyperactivation of calcineurin-NFAT signaling in skeletal muscle of DM1 mice

scientific article published on 27 March 2017

Muscle-specific expression of the RNA-binding protein Staufen1 induces progressive skeletal muscle atrophy via regulation of phosphatase tensin homolog

scientific article

Novel Roles for Staufen1 in Embryonal and Alveolar Rhabdomyosarcoma via c-myc-dependent and -independent events

scientific article published on 17 February 2017

Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies

scientific journal article

Protein arginine methylation facilitates cotranscriptional recruitment of pre-mRNA splicing factors.

scientific article published on 7 September 2010

Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression

scientific article published on February 2015

RNA binding protein RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells

scientific article published on 18 July 2017

Role of PRMTs in cancer: Could minor isoforms be leaving a mark?

scientific article

S. pombe replication protein Cdc18 (Cdc6) interacts with Swi6 (HP1) heterochromatin protein: region specific effects and replication timing in the centromere.

scientific article published on 15 January 2011

Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1

scientific article

Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier

scientific article published on 29 January 2016

Staufen1 impairs stress granule formation in skeletal muscle cells from myotonic dystrophy type 1 patients.

scientific article published on 30 March 2016

Staufen1s role as a splicing factor and a disease modifier in Myotonic Dystrophy Type I.

scientific article

Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing.

scientific article

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules

scientific article

The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing ⬇️

scientific article published on March 19, 2012

The U1 small nuclear ribonucleoprotein/5' splice site interaction affects U2AF65 binding to the downstream 3' splice site

scientific article published on February 1995

The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.

scientific article published in January 2007

The product of the survival of motor neuron (SMN) gene is a human telomerase-associated protein

scientific article

Tudor Domain Containing Protein 3 Promotes Tumorigenesis and Invasive Capacity of Breast Cancer Cells

scientific article

Tudor domains bind symmetrical dimethylated arginines

scientific article

eEF1A is a novel component of the mammalian nuclear protein export machinery

scientific article

hnRNP A1 regulates UV-induced NF-kappaB signalling through destabilization of cIAP1 mRNA.

scientific article published on 10 October 2008

List of works by Jocelyn Côté

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy

A novel function for the survival motoneuron protein as a translational regulator

A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy.

A protein-domain microarray identifies novel protein-protein interactions

A proteomic analysis of arginine-methylated protein complexes

Aberrant Splicing of tau Pre-mRNA Caused by Intronic Mutations Associated with the Inherited Dementia Frontotemporal Dementia with Parkinsonism Linked to Chromosome 17.

Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics

Alternative splicing yields protein arginine methyltransferase 1 isoforms with distinct activity, substrate specificity, and subcellular localization.

Alternatively spliced protein arginine methyltransferase 1 isoform PRMT1v2 promotes the survival and invasiveness of breast cancer cells.

Arginine methyltransferases as novel therapeutic targets for breast cancer

Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy.

Converging pathways involving microRNA-206 and the RNA-binding protein KSRP control post-transcriptionally utrophin A expression in skeletal muscle.

Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.

HuD interacts with survival motor neuron protein and can rescue spinal muscular atrophy-like neuronal defects.

IGF-1R Reduction Triggers Neuroprotective Signaling Pathways in Spinal Muscular Atrophy Mice.

Identification of the PRMT1v1 and PRMT1v2 specific interactomes by quantitative mass spectrometry in breast cancer cells.

In vivo NMDA receptor activation accelerates motor unit maturation, protects spinal motor neurons, and enhances SMN2 gene expression in severe spinal muscular atrophy mice.

KH-type splicing regulatory protein interacts with survival motor neuron protein and is misregulated in spinal muscular atrophy.

Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae.

Misregulation of calcium-handling proteins promotes hyperactivation of calcineurin-NFAT signaling in skeletal muscle of DM1 mice

Muscle-specific expression of the RNA-binding protein Staufen1 induces progressive skeletal muscle atrophy via regulation of phosphatase tensin homolog

Novel Roles for Staufen1 in Embryonal and Alveolar Rhabdomyosarcoma via c-myc-dependent and -independent events

Nuclear Fragile X Mental Retardation Protein is localized to Cajal bodies

Protein arginine methylation facilitates cotranscriptional recruitment of pre-mRNA splicing factors.

Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression

RNA binding protein RALY promotes Protein Arginine Methyltransferase 1 alternatively spliced isoform v2 relative expression and metastatic potential in breast cancer cells

Role of PRMTs in cancer: Could minor isoforms be leaving a mark?

S. pombe replication protein Cdc18 (Cdc6) interacts with Swi6 (HP1) heterochromatin protein: region specific effects and replication timing in the centromere.

Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1

Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier

Staufen1 impairs stress granule formation in skeletal muscle cells from myotonic dystrophy type 1 patients.

Staufen1s role as a splicing factor and a disease modifier in Myotonic Dystrophy Type I.

Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing.

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules

The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing ⬇️

The U1 small nuclear ribonucleoprotein/5' splice site interaction affects U2AF65 binding to the downstream 3' splice site

The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.

The product of the survival of motor neuron (SMN) gene is a human telomerase-associated protein

Tudor Domain Containing Protein 3 Promotes Tumorigenesis and Invasive Capacity of Breast Cancer Cells

Tudor domains bind symmetrical dimethylated arginines

eEF1A is a novel component of the mammalian nuclear protein export machinery

hnRNP A1 regulates UV-induced NF-kappaB signalling through destabilization of cIAP1 mRNA.