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List of works by Pedro Fernández-Salguero

A mesenchymal-like phenotype and expression of CD44 predict lack of apoptotic response to sorafenib in liver tumor cells

scientific article published on 04 August 2014

Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells.

scientific article

Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice.

scientific article

Aryl-hydrocarbon receptor-deficient mice are resistant to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced toxicity

scientific article

Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch

scientific article published on 5 December 2014

CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis.

scientific article published on 4 July 2016

CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice

scientific article published in September 1999

Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2.

scientific article published in March 2003

Characterization of the human dihydropyrimidine dehydrogenase gene

scientific article published on 01 August 1998

Correlation between catalytic activity and protein content for the polymorphically expressed dihydropyrimidine dehydrogenase in human lymphocytes.

scientific article

Differential regulation of mouse Ah receptor gene expression in cell lines of different tissue origins.

scientific article

Differential scanning calorimetry study of glycogen phosphorylase b-detergent interactions

scientific article published on 01 December 1992

Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects.

scientific article published on August 1998

Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer ⬇️

scientific article published on January 1, 1998

Dioxin Receptor Expression Inhibits Basal and Transforming Growth Factor β-induced Epithelial-to-mesenchymal Transition ⬇️

scientific article published on February 4, 2013

Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch.

scientific article

Dioxin receptor deficiency impairs angiogenesis by a mechanism involving VEGF-A depletion in the endothelium and transforming growth factor-beta overexpression in the stroma.

scientific article published on 18 July 2009

Dioxin receptor regulates aldehyde dehydrogenase to block melanoma tumorigenesis and metastasis.

scientific article published on 5 August 2015

Down-regulation of CYP1A2 induction during the maturation of mouse cerebellar granule cells in culture: role of nitric oxide accumulation

scientific article published in October 2003

Effect of immobilization on the activity of rat hepatic microsomal cytochrome P450 enzymes

scientific article published on 01 February 1993

Effect of phenobarbital on hepatic CYP1A1 and CYP1A2 in the Ahr-null mouse

scientific article published on 01 January 1998

Effect of thioridazine dosage on the debrisoquine hydroxylation phenotype in psychiatric patients with different CYP2D6 genotypes.

scientific article published in December 2001

Expression of CYP2A genes in human liver and extrahepatic tissues.

scientific article

Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling

scientific article published on 05 September 2008

Genomic instability in Gadd45a-deficient mice

scientific article published on 01 October 1999

Hepatic fibrosis and cytochrome P450: experimental models of fibrosis compared to AHR knockout mice

scientific article published on 01 May 2000

Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model

scientific article published on 9 June 2005

Improving cancer therapeutics by molecular profiling.

scientific article

L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke.

scientific article published on 30 October 2014

LTBP-1 blockade in dioxin receptor-null mouse embryo fibroblasts decreases TGF-beta activity: Role of extracellular proteases plasmin and elastase.

scientific article published on February 2006

Liver portal fibrosis in dioxin receptor-null mice that overexpress the latent transforming growth factor-beta-binding protein-1.

scientific article published in October 2004

Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGFbeta.

scientific article published on 12 May 2009

Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines

scientific article

New Trends in Aryl Hydrocarbon Receptor Biology

scientific article

Oculomotor deficits in aryl hydrocarbon receptor null mouse

scientific article

Overexpression of latent transforming growth factor-beta binding protein 1 (LTBP-1) in dioxin receptor-null mouse embryo fibroblasts

scientific article published on 3 February 2004

Potassium-induced apoptosis in rat cerebellar granule cells involves cell-cycle blockade at the G1/S transition.

scientific article published on December 2000

Proteasome inhibition induces nuclear translocation of the dioxin receptor through an Sp1 and protein kinase C-dependent pathway

scientific article published in October 2003

RNA-Seq Analysis to Measure the Expression of SINE Retroelements.

scientific article published on January 2016

Recruitment of CREB1 and histone deacetylase 2 (HDAC2) to the mouse Ltbp-1 promoter regulates its constitutive expression in a dioxin receptor-dependent manner

scientific article published on 30 April 2008

Regulation of cell survival by resveratrol involves inhibition of NF kappa B-regulated gene expression in prostate cancer cells.

scientific article published on July 2009

Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation

scientific article published in March 2004

Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kappaB.

scientific article published on May 2005

Role of CYP2E1 in the hepatotoxicity of acetaminophen

scientific article published on 01 May 1996

Selenocysteine tRNA[Ser]Sec levels and selenium-dependent glutathione peroxidase activity in mouse embryonic stem cells heterozygous for a targeted mutation in the tRNA[Ser]Sec gene.

scientific article published on July 1997

Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor.

scientific article published on 14 July 2015

Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development

scientific article

The CYP2 A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis ⬇️

scientific article published on January 1, 1995

The Dioxin receptor modulates Caveolin-1 mobilization during directional migration: role of cholesterol

scientific article published on 21 September 2014

The antiproliferative activity of resveratrol results in apoptosis in MCF-7 but not in MDA-MB-231 human breast cancer cells: cell-specific alteration of the cell cycle

scientific article published in November 2002

The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein.

scientific article published on 30 March 2007

The dioxin receptor controls β1 integrin activation in fibroblasts through a Cbp-Csk-Src pathway.

scientific article

The dioxin receptor has tumor suppressor activity in melanoma growth and metastasis.

scientific article published on 10 July 2013

The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding.

scientific article published on 12 January 2006

The dioxin receptor regulates the constitutive expression of the vav3 proto-oncogene and modulates cell shape and adhesion.

scientific article published on 21 January 2009

Transcriptional factor aryl hydrocarbon receptor (Ahr) controls cardiovascular and respiratory functions by regulating the expression of the Vav3 proto-oncogene

scientific article

piRNA-associated proteins and retrotransposons are differentially expressed in murine testis and ovary of aryl hydrocarbon receptor deficient mice.

scientific article published on December 2016

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