List of works - Ashok Kumar

A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1.

scientific article published on 3 April 2018

Assay for redox-sensitive kinases

scientific article published on 01 January 1999

Canonical NF-κB signaling regulates satellite stem cell homeostasis and function during regenerative myogenesis

scientific article published on 01 January 2019

Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-kappaB activation

scientific article published on 01 March 1998

Distinct roles of TRAF6 and TAK1 in the regulation of adipocyte survival, thermogenesis program, and high-fat diet-induced obesity.

scientific article published on 3 November 2017

Distinct roles of TRAF6 at early and late stages of muscle pathology in the mdx model of Duchenne muscular dystrophy.

scientific article published on 24 October 2013

Distinct signaling pathways are activated in response to mechanical stress applied axially and transversely to skeletal muscle fibers.

scientific article

Dlk1 is necessary for proper skeletal muscle development and regeneration

scientific article

ER stress in skeletal muscle remodeling and myopathies

scientific article

Effect of Dalton's lymphoma on the antigen presentation of murine peritoneal macrophages ⬇️

scientific article published on 01 June 1995

Effect of cisplatin administration on the proliferation and differentiation of bone marrow cells of tumour‐bearing mice ⬇️

scientific article published on June 1, 1995

Effect of cisplatin and FK565 on the activation of tumor-associated and bone marrow-derived macrophages by Dalton's lymphoma

scientific article published on 01 January 1995

Effect of prolactin on nitric oxide and interleukin-1 production of murine peritoneal macrophages: Role of Ca2+ and protein kinase C ⬇️

scientific article published on 01 March 1997

Effects of omega-3 on matrix metalloproteinase-9, myoblast transplantation and satellite cell activation in dystrophin-deficient muscle fibers

scientific article published on 17 June 2017

Elevated levels of TWEAK in skeletal muscle promote visceral obesity, insulin resistance, and metabolic dysfunction.

scientific article published on 2 December 2014

Elevated levels of active matrix metalloproteinase-9 cause hypertrophy in skeletal muscle of normal and dystrophin-deficient mdx mice.

scientific article

Emerging roles of ER stress and unfolded protein response pathways in skeletal muscle health and disease

scientific article published on 8 February 2017

Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-kappaB activation, IkappaB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells.

scientific article

Fibroblast growth factor inducible 14 (Fn14) is required for the expression of myogenic regulatory factors and differentiation of myoblasts into myotubes. Evidence for TWEAK-independent functions of Fn14 during myogenesis

scientific article

Gene Profiling Studies in Skeletal Muscle by Quantitative Real-Time Polymerase Chain Reaction Assay ⬇️

scientific article published on January 1, 2012

Genomic profiling of messenger RNAs and microRNAs reveals potential mechanisms of TWEAK-induced skeletal muscle wasting in mice

scientific article

Human immunodeficiency virus-1-tat induces matrix metalloproteinase-9 in monocytes through protein tyrosine phosphatase-mediated activation of nuclear transcription factor NF-kappaB.

scientific article

Isolation, Culture, and Staining of Single Myofibers

scientific article published on October 2016

Isolation, Culturing, and Differentiation of Primary Myoblasts from Skeletal Muscle of Adult Mice

scientific article published on May 2017

Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy.

scientific article published on 28 April 2009

Matrix metalloproteinase-9 inhibition improves proliferation and engraftment of myogenic cells in dystrophic muscle of mdx mice

scientific article

Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy.

scientific article published on March 2003

Mechanical stretch activates nuclear factor-kappaB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: implications in asthma

scientific article published in October 2003

MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice

scientific article published on 01 October 2018

MyD88 promotes myoblast fusion in a cell-autonomous manner

scientific article published on 20 November 2017

Noncoding RNAs in the regulation of skeletal muscle biology in health and disease.

scientific article

Nuclear factor-kappa B signaling in skeletal muscle atrophy.

scientific article

Osteopontin-Stimulated Expression of Matrix Metalloproteinase-9 Causes Cardiomyopathy in the mdx Model of Duchenne Muscular Dystrophy ⬇️

scientific article published on September 1, 2011

PERK regulates skeletal muscle mass and contractile function in adult mice

scientific article published on 11 September 2018

Physiological Biomimetic Culture System for Pig and Human Heart Slices

scientific article published on 16 July 2019

Proinflammatory cytokine tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) suppresses satellite cell self-renewal through inversely modulating Notch and NF-κB signaling pathways

scientific article published on 22 October 2013

Protein-DNA array-based identification of transcription factor activities differentially regulated in skeletal muscle of normal and dystrophin-deficient mdx mice.

scientific article published on 17 February 2008

Reciprocal Interaction between TRAF6 and Notch Signaling Regulates Adult Myofiber Regeneration upon Injury ⬇️

scientific article published on October 1, 2012

Regulation of phosphatidylinositol 3-kinase (PI3K)/Akt and nuclear factor-kappa B signaling pathways in dystrophin-deficient skeletal muscle in response to mechanical stretch.

scientific article published in September 2006

Regulatory circuitry of TWEAK-Fn14 system and PGC-1α in skeletal muscle atrophy program.

scientific article

Sanguinarine (Pseudochelerythrine) Is a Potent Inhibitor of NF-κB Activation, IκBα Phosphorylation, and Degradation ⬇️

scientific article published on November 28, 1997

Signaling Mechanisms in Mammalian Myoblast Fusion ⬇️

scientific article published on April 23, 2013

TAK1 modulates satellite stem cell homeostasis and skeletal muscle repair

scientific article

TAK1 regulates skeletal muscle mass and mitochondrial function

scientific article published on 8 February 2018

TNF-like weak inducer of apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta-activated kinase 1

scientific article published on February 2009

TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine

scientific article

TRAF6 coordinates the activation of autophagy and ubiquitin-proteasome systems in atrophying skeletal muscle ⬇️

scientific article published on May 1, 2011

TRAF6 regulates satellite stem cell self-renewal and function during regenerative myogenesis.

scientific article published on 30 November 2015

TWEAK and TRAF6 regulate skeletal muscle atrophy.

scientific article

TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases.

scientific article

TWEAK promotes exercise intolerance by decreasing skeletal muscle oxidative phosphorylation capacity.

scientific article published on 08 July 2013

TWEAK/Fn14 Signaling Axis Mediates Skeletal Muscle Atrophy and Metabolic Dysfunction.

scientific article published on 27 January 2014

Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice. ⬇️

scientific article

The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms

scientific article published on 30 January 2012

The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

scientific article

The TWEAK-Fn14 System: Breaking the Silence of Cytokine-Induced Skeletal Muscle Wasting ⬇️

scientific article published on January 1, 2012

The TWEAK-Fn14 dyad is involved in age-associated pathological changes in skeletal muscle

scientific article

The TWEAK-Fn14 pathway: a potent regulator of skeletal muscle biology in health and disease

scientific article

The Toll-Like Receptor/MyD88/XBP1 Signaling Axis Mediates Skeletal Muscle Wasting during Cancer Cachexia

scientific article published on 16 July 2019

Therapeutic potential of matrix metalloproteinases in Duchenne muscular dystrophy

scientific article published on April 2014

Toll-like receptor signalling in regenerative myogenesis: friend and foe.

scientific article published on 09 March 2016

Transgenic overexpression of pregnancy-associated plasma protein-A increases the somatic growth and skeletal muscle mass in mice.

scientific article

Tumor necrosis factor-alpha augments matrix metalloproteinase-9 production in skeletal muscle cells through the activation of transforming growth factor-beta-activated kinase 1 (TAK1)-dependent signaling pathway

scientific article

Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein.

scientific article published on 6 February 2006

Tumor necrosis factor-α regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells

scientific article

Wasting mechanisms in muscular dystrophy.

scientific article published on 11 May 2013

List of works by Ashok Kumar

A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1.

Assay for redox-sensitive kinases

Canonical NF-κB signaling regulates satellite stem cell homeostasis and function during regenerative myogenesis

Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-kappaB activation

Distinct roles of TRAF6 and TAK1 in the regulation of adipocyte survival, thermogenesis program, and high-fat diet-induced obesity.

Distinct roles of TRAF6 at early and late stages of muscle pathology in the mdx model of Duchenne muscular dystrophy.

Distinct signaling pathways are activated in response to mechanical stress applied axially and transversely to skeletal muscle fibers.

Dlk1 is necessary for proper skeletal muscle development and regeneration

ER stress in skeletal muscle remodeling and myopathies

Effect of Dalton's lymphoma on the antigen presentation of murine peritoneal macrophages ⬇️

Effect of cisplatin administration on the proliferation and differentiation of bone marrow cells of tumour‐bearing mice ⬇️

Effect of cisplatin and FK565 on the activation of tumor-associated and bone marrow-derived macrophages by Dalton's lymphoma

Effect of prolactin on nitric oxide and interleukin-1 production of murine peritoneal macrophages: Role of Ca2+ and protein kinase C ⬇️

Effects of omega-3 on matrix metalloproteinase-9, myoblast transplantation and satellite cell activation in dystrophin-deficient muscle fibers

Elevated levels of TWEAK in skeletal muscle promote visceral obesity, insulin resistance, and metabolic dysfunction.

Elevated levels of active matrix metalloproteinase-9 cause hypertrophy in skeletal muscle of normal and dystrophin-deficient mdx mice.

Emerging roles of ER stress and unfolded protein response pathways in skeletal muscle health and disease

Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-kappaB activation, IkappaB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells.

Fibroblast growth factor inducible 14 (Fn14) is required for the expression of myogenic regulatory factors and differentiation of myoblasts into myotubes. Evidence for TWEAK-independent functions of Fn14 during myogenesis

Gene Profiling Studies in Skeletal Muscle by Quantitative Real-Time Polymerase Chain Reaction Assay ⬇️

Genomic profiling of messenger RNAs and microRNAs reveals potential mechanisms of TWEAK-induced skeletal muscle wasting in mice

Human immunodeficiency virus-1-tat induces matrix metalloproteinase-9 in monocytes through protein tyrosine phosphatase-mediated activation of nuclear transcription factor NF-kappaB.

Isolation, Culture, and Staining of Single Myofibers

Isolation, Culturing, and Differentiation of Primary Myoblasts from Skeletal Muscle of Adult Mice

Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy.

Matrix metalloproteinase-9 inhibition improves proliferation and engraftment of myogenic cells in dystrophic muscle of mdx mice

Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy.

Mechanical stretch activates nuclear factor-kappaB, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: implications in asthma

MyD88 is required for satellite cell-mediated myofiber regeneration in dystrophin-deficient mdx mice

MyD88 promotes myoblast fusion in a cell-autonomous manner

Noncoding RNAs in the regulation of skeletal muscle biology in health and disease.

Nuclear factor-kappa B signaling in skeletal muscle atrophy.

Osteopontin-Stimulated Expression of Matrix Metalloproteinase-9 Causes Cardiomyopathy in the mdx Model of Duchenne Muscular Dystrophy ⬇️

PERK regulates skeletal muscle mass and contractile function in adult mice

Physiological Biomimetic Culture System for Pig and Human Heart Slices

Proinflammatory cytokine tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) suppresses satellite cell self-renewal through inversely modulating Notch and NF-κB signaling pathways

Protein-DNA array-based identification of transcription factor activities differentially regulated in skeletal muscle of normal and dystrophin-deficient mdx mice.

Reciprocal Interaction between TRAF6 and Notch Signaling Regulates Adult Myofiber Regeneration upon Injury ⬇️

Regulation of phosphatidylinositol 3-kinase (PI3K)/Akt and nuclear factor-kappa B signaling pathways in dystrophin-deficient skeletal muscle in response to mechanical stretch.

Regulatory circuitry of TWEAK-Fn14 system and PGC-1α in skeletal muscle atrophy program.

Sanguinarine (Pseudochelerythrine) Is a Potent Inhibitor of NF-κB Activation, IκBα Phosphorylation, and Degradation ⬇️

Signaling Mechanisms in Mammalian Myoblast Fusion ⬇️

TAK1 modulates satellite stem cell homeostasis and skeletal muscle repair

TAK1 regulates skeletal muscle mass and mitochondrial function

TNF-like weak inducer of apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta-activated kinase 1

TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine

TRAF6 coordinates the activation of autophagy and ubiquitin-proteasome systems in atrophying skeletal muscle ⬇️

TRAF6 regulates satellite stem cell self-renewal and function during regenerative myogenesis.

TWEAK and TRAF6 regulate skeletal muscle atrophy.

TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases.

TWEAK promotes exercise intolerance by decreasing skeletal muscle oxidative phosphorylation capacity.

TWEAK/Fn14 Signaling Axis Mediates Skeletal Muscle Atrophy and Metabolic Dysfunction.

Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice. ⬇️

The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms

The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

The TWEAK-Fn14 System: Breaking the Silence of Cytokine-Induced Skeletal Muscle Wasting ⬇️

The TWEAK-Fn14 dyad is involved in age-associated pathological changes in skeletal muscle

The TWEAK-Fn14 pathway: a potent regulator of skeletal muscle biology in health and disease

The Toll-Like Receptor/MyD88/XBP1 Signaling Axis Mediates Skeletal Muscle Wasting during Cancer Cachexia

Therapeutic potential of matrix metalloproteinases in Duchenne muscular dystrophy

Toll-like receptor signalling in regenerative myogenesis: friend and foe.

Transgenic overexpression of pregnancy-associated plasma protein-A increases the somatic growth and skeletal muscle mass in mice.

Tumor necrosis factor-alpha augments matrix metalloproteinase-9 production in skeletal muscle cells through the activation of transforming growth factor-beta-activated kinase 1 (TAK1)-dependent signaling pathway

Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-kappaB and degradation of MyoD protein.

Tumor necrosis factor-α regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells

Wasting mechanisms in muscular dystrophy.