List of works - Yassine Amrani

Abnormal corticosteroid signalling in airway smooth muscle: mechanisms and perspectives for the treatment of severe asthma.

scientific article published on 27 May 2015

Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?

scientific article

Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact.

scientific article

Airway smooth muscle modulation and airway hyper-responsiveness in asthma: new cellular and molecular paradigms

scientific article published on May 2006

Airway smooth muscle: contraction and beyond.

scientific article

An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma

scientific article

Basal p38 mitogen-activated protein kinase regulates unliganded glucocorticoid receptor function in airway smooth muscle cells.

scientific article published on February 2014

Bidirectional Counterregulation of Human Lung Mast Cell and Airway Smooth Muscle β2 Adrenoceptors

scientific article

Biphasic increase in cytosolic free calcium induced by bradykinin and histamine in cultured tracheal smooth muscle cells: is the sustained phase artifactual?

scientific article published on 01 December 1994

Bradykinin induces interleukin-6 production in human airway smooth muscle cells: modulation by Th2 cytokines and dexamethasone.

scientific article published in March 2003

Bronchial hyperresponsiveness: insights into new signaling molecules.

scientific article published on June 2004

CD38 expression is insensitive to steroid action in cells treated with tumor necrosis factor-alpha and interferon-gamma by a mechanism involving the up-regulation of the glucocorticoid receptor beta isoform

scientific article

Ca2+ increase and Ca(2+)-influx in human tracheal smooth muscle cells: role of Ca2+ pools controlled by sarco-endoplasmic reticulum Ca(2+)-ATPase 2 isoform.

scientific article published on August 1995

Comparative action of new highly potent bradykinin receptor antagonists in the guinea-pig trachea

scientific article published in August 1993

Counterregulation of beta(2)-adrenoceptor function in human mast cells by stem cell factor

scientific article published on 27 October 2009

Cytokines alter glucocorticoid receptor phosphorylation in airway cells: role of phosphatases.

scientific article

Cytokines induce an early steroid resistance in airway smooth muscle cells: novel role of interferon regulatory factor-1.

scientific article published on 18 October 2007

D prostanoid receptor 2 (chemoattractant receptor-homologous molecule expressed on TH2 cells) protein expression in asthmatic patients and its effects on bronchial epithelial cells

scientific article

Effect of the plant derivative Compound A on the production of corticosteroid-resistant chemokines in airway smooth muscle cells.

scientific article published on 21 April 2015

Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness.

scientific article published on 29 January 2008

Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13

scientific article

Fetal human airway smooth muscle cell production of leukocyte chemoattractants is differentially regulated by fluticasone

scientific article

Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells

scientific article published on 31 July 2013

G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells.

scientific article published on October 2005

Gene expression profiling of flaxseed in mouse lung tissues-modulation of toxicologically relevant genes ⬇️

scientific article published on April 20, 2012

Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells

scientific article

Histamine mobilizes intracellular Ca(2+)-pools sensitive to thapsigargin in cultured guinea-pig tracheal smooth muscle cells

scientific article published in April 1995

Human lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca(2+)-dependent and regulated by KCa3.1 K(+) channels

scientific article

IFN-γ-induced JAK/STAT, but not NF-κB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells

scientific article

IL-33 drives airway hyper-responsiveness through IL-13-mediated mast cell: airway smooth muscle crosstalk

scientific article published on 16 March 2015

Immunopathogenesis of severe asthma.

scientific article published on January 2011

Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent.

scientific article

Inhibition of tumor necrosis factor-alpha-inducible inflammatory genes by interferon-gamma is associated with altered nuclear factor-kappaB transactivation and enhanced histone deacetylase activity

scientific article published on 15 November 2006

Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation

scientific article

Is airway smooth muscle the "missing link" modulating airway inflammation in asthma?

scientific article published on January 2008

Lipoxin A4 Attenuates Constitutive and TGF-β1-Dependent Profibrotic Activity in Human Lung Myofibroblasts

scientific article

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction

scientific article (publication date: 19 April 2016)

Mast cell activation involves plasma membrane potential- and thapsigargin-sensitive intracellular calcium pools

scientific article published on 01 January 1995

Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway.

scientific article published on 5 February 2004

Oxygen dose responsiveness of human fetal airway smooth muscle cells.

scientific article published on 24 August 2012

Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen-sensitized mice

scientific article published in April 2008

Potentiation by tumour necrosis factor-alpha of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle cells.

scientific article published on January 1995

Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma.

scientific article published on 9 August 2016

Response to C3a, mast cells, and asthma

scientific article published on 01 February 2006

Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.

scientific article published on 13 July 2009

Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells

scientific article published in October 2003

TGF-beta potentiates airway smooth muscle responsiveness to bradykinin

scientific article published on 27 May 2005

Targeting TNF-alpha: a novel therapeutic approach for asthma

scientific article

The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells

scientific article

Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids

scientific article published on 29 March 2006

Tumor necrosis factor alpha modulates airway smooth muscle function via the autocrine action of interferon beta

scientific article

Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway

scientific article

Vitamin D attenuates cytokine-induced remodeling in human fetal airway smooth muscle cells

scientific article

List of works by Yassine Amrani

Abnormal corticosteroid signalling in airway smooth muscle: mechanisms and perspectives for the treatment of severe asthma.

Activation of tumor necrosis factor receptor 1 in airway smooth muscle: a potential pathway that modulates bronchial hyper-responsiveness in asthma?

Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact.

Airway smooth muscle modulation and airway hyper-responsiveness in asthma: new cellular and molecular paradigms

Airway smooth muscle: contraction and beyond.

An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma

Basal p38 mitogen-activated protein kinase regulates unliganded glucocorticoid receptor function in airway smooth muscle cells.

Bidirectional Counterregulation of Human Lung Mast Cell and Airway Smooth Muscle β2 Adrenoceptors

Biphasic increase in cytosolic free calcium induced by bradykinin and histamine in cultured tracheal smooth muscle cells: is the sustained phase artifactual?

Bradykinin induces interleukin-6 production in human airway smooth muscle cells: modulation by Th2 cytokines and dexamethasone.

Bronchial hyperresponsiveness: insights into new signaling molecules.

CD38 expression is insensitive to steroid action in cells treated with tumor necrosis factor-alpha and interferon-gamma by a mechanism involving the up-regulation of the glucocorticoid receptor beta isoform

Ca2+ increase and Ca(2+)-influx in human tracheal smooth muscle cells: role of Ca2+ pools controlled by sarco-endoplasmic reticulum Ca(2+)-ATPase 2 isoform.

Comparative action of new highly potent bradykinin receptor antagonists in the guinea-pig trachea

Counterregulation of beta(2)-adrenoceptor function in human mast cells by stem cell factor

Cytokines alter glucocorticoid receptor phosphorylation in airway cells: role of phosphatases.

Cytokines induce an early steroid resistance in airway smooth muscle cells: novel role of interferon regulatory factor-1.

D prostanoid receptor 2 (chemoattractant receptor-homologous molecule expressed on TH2 cells) protein expression in asthmatic patients and its effects on bronchial epithelial cells

Effect of the plant derivative Compound A on the production of corticosteroid-resistant chemokines in airway smooth muscle cells.

Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness.

Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13

Fetal human airway smooth muscle cell production of leukocyte chemoattractants is differentially regulated by fluticasone

Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells

G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells.

Gene expression profiling of flaxseed in mouse lung tissues-modulation of toxicologically relevant genes ⬇️

Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells

Histamine mobilizes intracellular Ca(2+)-pools sensitive to thapsigargin in cultured guinea-pig tracheal smooth muscle cells

Human lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca(2+)-dependent and regulated by KCa3.1 K(+) channels

IFN-γ-induced JAK/STAT, but not NF-κB, signaling pathway is insensitive to glucocorticoid in airway epithelial cells

IL-33 drives airway hyper-responsiveness through IL-13-mediated mast cell: airway smooth muscle crosstalk

Immunopathogenesis of severe asthma.

Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is KCa3.1-dependent.

Inhibition of tumor necrosis factor-alpha-inducible inflammatory genes by interferon-gamma is associated with altered nuclear factor-kappaB transactivation and enhanced histone deacetylase activity

Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation

Is airway smooth muscle the "missing link" modulating airway inflammation in asthma?

Lipoxin A4 Attenuates Constitutive and TGF-β1-Dependent Profibrotic Activity in Human Lung Myofibroblasts

Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction

Mast cell activation involves plasma membrane potential- and thapsigargin-sensitive intracellular calcium pools

Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway.

Oxygen dose responsiveness of human fetal airway smooth muscle cells.

Ozone inhalation induces exacerbation of eosinophilic airway inflammation and hyperresponsiveness in allergen-sensitized mice

Potentiation by tumour necrosis factor-alpha of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle cells.

Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma.

Response to C3a, mast cells, and asthma

Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.

Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells

TGF-beta potentiates airway smooth muscle responsiveness to bradykinin

Targeting TNF-alpha: a novel therapeutic approach for asthma

The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells

Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids

Tumor necrosis factor alpha modulates airway smooth muscle function via the autocrine action of interferon beta

Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway

Vitamin D attenuates cytokine-induced remodeling in human fetal airway smooth muscle cells