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List of works by Frank C Schroeder

2D NMR-based metabolomics uncovers interactions between conserved biochemical pathways in the model organism Caenorhabditis elegans

scientific article published on 26 November 2012

2D NMR-spectroscopic screening reveals polyketides in ladybugs

scientific article

3,7-Isoquinoline quinones from the ascidian tunicate Ascidia virginea

scientific article published on 01 July 2017

A Forward Genetic Screen for Molecules Involved in Pheromone-Induced Dauer Formation in Caenorhabditis elegans

scientific article published on 14 March 2016

A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.

scientific article published on 8 September 2017

A backup plan for self-protection: S-methylation of holomycin biosynthetic intermediates in Streptomyces clavuligerus ⬇️

scientific article published on 24 October 2012

A blend of small molecules regulates both mating and development in Caenorhabditis elegans. ⬇️

scientific article published on 23 July 2008

A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells

scientific article

A family of indoles regulate virulence and Shiga toxin production in pathogenic E. coli

scientific article

A modular library of small molecule signals regulates social behaviors in Caenorhabditis elegans

scientific article

A new approach to natural products discovery exemplified by the identification of sulfated nucleosides in spider venom

scientific article

A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus ⬇️

scientific article published on February 2013

A photocleavable masked nuclear-receptor ligand enables temporal control of C. elegans development

scientific article

A shortcut to identifying small molecule signals that regulate behavior and development in Caenorhabditis elegans

scholarly article

Actin-aggregating cucurbitacins from Physocarpus capitatus ⬇️

scientific article

Activation of a G protein-coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans

scientific article

Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARγ) agonist with potent glucose-lowering properties

scientific article published on 18 May 2013

Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria

scientific article published on 5 January 2016

Amorfrutins Are Natural PPARγ Agonists with Potent Anti-inflammatory Properties

scientific article published on 4 May 2015

Amorfrutins are potent antidiabetic dietary natural products

scientific article

An Oligomer-Based Approach to Skeletal Diversity in Small-Molecule Synthesis

scientific article published on 01 November 2006

An Untargeted Approach for Revealing Electrophilic Metabolites

scientific article published on 19 October 2020

An excreted small molecule promotes C. elegans reproductive development and aging

scientific article published on 18 July 2019

Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C. elegans

scientific article published in July 2013

Ascaroside expression in Caenorhabditis elegans is strongly dependent on diet and developmental stage

scientific article

Ascaroside signaling in C. elegans

scientific article published on 18 January 2013

Ascaroside signaling is widely conserved among nematodes

scientific article

Aspirin's Active Metabolite Salicylic Acid Targets High Mobility Group Box 1 to Modulate Inflammatory Responses

scientific article

Attraction to pheromones in Caenorhabditis elegans can be reversed through associative learning:

B. subtilis GS67 protects C. elegans from Gram-positive pathogens via fengycin-mediated microbial antagonism

scientific article published on 6 November 2014

BLIMP-1/BLMP-1 and Metastasis-Associated Protein Regulate Stress Resistant Development in Caenorhabditis elegans.

scientific article

Biology and genome of a newly discovered sibling species of Caenorhabditis elegans

scientific article published in Nature Communications

Biosynthesis of Modular Ascarosides in C. elegans

Biosynthesis of Modular Ascarosides in C. elegans

scientific article

Biosynthesis of thiamin thiazole in eukaryotes: conversion of NAD to an advanced intermediate

scientific article published on 20 February 2007

Biosynthetic chlorination of the piperazate residue in kutzneride biosynthesis by KthP.

scientific article published on 20 June 2011

Chemical defense of an Asian snake reflects local availability of toxic prey and hatchling diet.

scientific article published on 17 December 2012

Chemical detoxification of small molecules by Caenorhabditis elegans.

scientific article

Chemoenzymatic synthesis of thiazolyl peptide natural products featuring an enzyme-catalyzed formal [4 + 2] cycloaddition

scientific article

Chemosensation of bacterial secondary metabolites modulates neuroendocrine signaling and behavior of C. elegans

scientific article

Chiral silylation reagents: determining configuration via NMR-spectroscopic coanalysis

scientific article published on September 2004

Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans

scholarly article published 3 March 2018

Co-option of neurotransmitter signaling for inter-organismal communication in C. elegans

scientific article published on 18 July 2019

Combinatorial chemistry in nematodes: modular assembly of primary metabolism-derived building blocks.

scientific article

Comparative metabolomics reveals biogenesis of ascarosides, a modular library of small-molecule signals in C. elegans

scientific article

Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan

scientific article published on January 2014

Comparative metabolomics with Metaboseek reveals functions of a conserved fat metabolism pathway in C. elegans

scientific article published on 10 February 2022

Complex small-molecule architectures regulate phenotypic plasticity in a nematode

scientific article

Conserved Responses in a War of Small Molecules between a Plant-Pathogenic Bacterium and Fungi.

scientific article published on 22 May 2018

Conserved nematode signalling molecules elicit plant defenses and pathogen resistance

scientific article published on 23 July 2015

Contrasting responses within a single neuron class enable sex-specific attraction in Caenorhabditis elegans

scientific article

Copper starvation induces antimicrobial isocyanide integrated into two distinct biosynthetic pathways in fungi ⬇️

Correlating secondary metabolite production with genetic changes using differential analysis of 2D NMR spectra

scientific article published on January 2012

Cyclic cis-Locked Phospho-Dipeptides Reduce Entry of AβPP into Amyloidogenic Processing Pathway.

scientific article published on 21 September 2016

Deep Interrogation of Metabolism Using a Pathway-Targeted Click-Chemistry Approach

scientific article published on 14 October 2020

Defensive Chemistry of Lycid Beetles and of Mimetic Cerambycid Beetles that Feed on Them

scientific article published on January 2008

Density dependence in Caenorhabditis larval starvation

scientific article published on 27 September 2013

Detecting the interaction of peptide ligands with plant membrane receptors

article

Dietary sequestration of defensive steroids in nuchal glands of the Asian snake Rhabdophis tigrinus

scientific article

Differential analysis of 2D NMR spectra: new natural products from a pilot-scale fungal extract library

scientific article published on 29 January 2007

Diketopiperazine Formation in Fungi Requires Dedicated Cyclization and Thiolation Domains

scientific article published on 28 August 2019

Discovery of a novel pharmacological and structural class of gamma secretase modulators derived from the extract of Actaea racemosa

scientific article

Editorial overview: Omics techniques to map the chemistry of life

scientific article

Elucidating the Rimosamide-Detoxin Natural Product Families and Their Biosynthesis Using Metabolite/Gene Cluster Correlations. ⬇️

scientific article

Endogenous NHR ligands: metabolomics to the rescue

scientific article published on July 2014

Enzymatic generation of the antimetabolite gamma,gamma-dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete

scientific article

Erratum: Mating dynamics in a nematode with three sexes and its evolutionary implications

scientific article

Ethylene signaling regulates natural variation in the abundance of antifungal acetylated diferuloylsucroses and Fusarium graminearum resistance in maize seedling roots

scientific article published on 02 November 2018

Experimental methods for dissecting the terraincognita of protein-metabolite interactomes

scientific article published in 2021

Extending the scope of NMR spectroscopy with microcoil probes

scientific article

Functional Conservation and Divergence of daf-22 Paralogs in Pristionchus pacificus Dauer Development.

scientific article published on 28 April 2016

Fungal Isocyanide Synthases and Xanthocillin Biosynthesis in Aspergillus fumigatus. ⬇️

scientific article published on 29 May 2018

Grass roots chemistry: meta-tyrosine, an herbicidal nonprotein amino acid

scholarly article

Hierarchical alignment and full resolution pattern recognition of 2D NMR spectra: application to nematode chemical ecology.

scientific article

Highly α-selective hydrolysis of α,β-epoxyalcohols using tetrabutylammonium fluoride

scientific article

Homologous NRPS-like gene clusters mediate redundant small-molecule biosynthesis in Aspergillus flavus ⬇️

scientific article published on 20 December 2012

Host recognition by the tobacco hornworm is mediated by a host plant compound.

scientific article

Human GAPDH Is a Target of Aspirin's Primary Metabolite Salicylic Acid and Its Derivatives

scientific article

Hydroquinone: a general phagostimulating pheromone in termites

scientific article published in January 2002

Identification of Uric Acid Gluconucleoside-Ascaroside Conjugates in Caenorhabditis elegans by Combining Synthesis and MicroED

scientific article published on 21 August 2020

Identification of cryptic products of the gliotoxin gene cluster using NMR-based comparative metabolomics and a model for gliotoxin biosynthesis

scientific article

Identification of indole glucosinolate breakdown products with antifeedant effects on Myzus persicae (green peach aphid).

scientific article

Identification of multiple salicylic acid-binding proteins using two high throughput screens.

scientific article

Identification of xanthurenic acid 8-O-beta-D-glucoside and xanthurenic acid 8-O-sulfate as human natriuretic hormones

scientific article

Improved Synthesis for Modular Ascarosides Uncovers Biological Activity.

scientific article

Insect Natural Products

scholarly article published 2010

Interaction of structure-specific and promiscuous G-protein-coupled receptors mediates small-molecule signaling in Caenorhabditis elegans

scientific article

Interspecific nematode signals regulate dispersal behavior

scientific article (publication date: 2012)

Intestinal peroxisomal fatty acid β-oxidation regulates neural serotonin signaling through a feedback mechanism

scientific article published on 05 December 2019

Isobutylamides of unsaturated fatty acids from Chrysanthemum morifolium associated with host-plant resistance against the western flower thrips

scientific article published in September 2003

Larval crowding accelerates C. elegans development and reduces lifespan

scientific article

Linking Genomic and Metabolomic Natural Variation Uncovers Nematode Pheromone Biosynthesis

scientific article published on 17 May 2018

Males shorten the life span of C. elegans hermaphrodites via secreted compounds

scientific article

Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

scientific article published in 2021

Mating dynamics in a nematode with three sexes and its evolutionary implications

scientific article

Mayolenes: labile defensive lipids from the glandular hairs of a caterpillar (Pieris rapae).

scientific article

Metabolic Interplay between the Asian Citrus Psyllid and Its Profftella Symbiont: An Achilles' Heel of the Citrus Greening Insect Vector

scientific article published on 18 November 2015

Metabolome-Scale Genome-Wide Association Studies Reveal Chemical Diversity and Genetic Control of Maize Specialized Metabolites

scientific article published on 28 March 2019

Metabolome-scale genome-wide association studies reveal chemical diversity and genetic control of maize specialized metabolites

Metabolomic "Dark Matter" Dependent on Peroxisomal β-Oxidation in Caenorhabditis elegans

scientific article published on 5 February 2018

Microfluidic chamber arrays for whole-organism behavior-based chemical screening

scientific article

Modular assembly of primary metabolic building blocks: a chemical language in C. elegans

scientific article

Modular metabolite assembly in C. elegans depends on carboxylesterases and formation of lysosome-related organelles

scientific article published on 16 October 2020

Molecular Determinants of the Regulation of Development and Metabolism by Neuronal eIF2α Phosphorylation in Caenorhabditis elegans

scientific article

N-methylquinolinium 2-carboxylate, a defensive betaine from Photuris versicolor fireflies.

scientific article published in February 1999

NMR in metabolomics and natural products research: two sides of the same coin

scientific article published on 2 September 2011

NMR-spectroscopic analysis of mixtures: from structure to function

scientific article

NMR-spectroscopic screening of spider venom reveals sulfated nucleosides as major components for the brown recluse and related species

scholarly article

NRPS-Derived Isoquinolines and Lipopetides Mediate Antagonism between Plant Pathogenic Fungi and Bacteria. ⬇️

scientific article

Natural Product and Natural Product-Derived Gamma Secretase Modulators from Actaea Racemosa Extracts

scientific article published on 30 June 2015

Natural diversity in the predatory behavior facilitates the establishment of a robust model strain for nematode-trapping fungi

scientific article published on 11 March 2020

Natural variation in arsenic toxicity is explained by differences in branched chain amino acid catabolism

article

Natural variation in dauer pheromone production and sensing supports intraspecific competition in nematodes

scientific article

Nematode signaling molecules derived from multimodular assembly of primary metabolic building blocks

scientific article published on 18 March 2015

Nematode-trapping fungi eavesdrop on nematode pheromones

scientific article

Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey

scientific article published on 18 January 2017

NeuCode Labeling in Nematodes: Proteomic and Phosphoproteomic Impact of Ascaroside Treatment in Caenorhabditis elegans

scientific article published on 21 September 2015

New Non-Glycosidic Diterpenes from the Leaves ofSteviarebaudiana

scientific article published on 01 October 2003

New Silyl Ether Reagents for the Absolute Stereochemical Determination of Secondary Alcohols

scientific article published on 01 May 2003

Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus ⬇️

scientific article

Phaeosphaeride A, an inhibitor of STAT3-dependent signaling isolated from an endophytic fungus ⬇️

scientific article published on August 2006

Pheromone sensing regulates Caenorhabditis elegans lifespan and stress resistance via the deacetylase SIR-2.1.

scientific article published on 18 March 2013

Pheromone-sensing neurons regulate peripheral lipid metabolism in Caenorhabditis elegans

scientific article

Phevamine A, a small molecule that suppresses plant immune responses

article published in the Proceedings of the National Academy of Sciences of the United States of America

Photoaffinity probes for nematode pheromone receptor identification

scientific article published on 01 December 2019

Pinoresinol: A lignol of plant origin serving for defense in a caterpillar

scientific article

Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus. ⬇️

scientific article published on 11 April 2016

Polyazamacrolides from ladybird beetles: ring-size selective oligomerization

scientific article published on November 1998

Predator-secreted sulfolipids induce defensive responses in C. elegans

scientific article published on 19 March 2018

Predator-secreted sulfolipids induce fear-like defense responses inC. elegans

article

Production of a cyanogenic secretion by a thyridid caterpillar (Calindoea trifascialis, Thyrididae, Lepidoptera).

scientific article published in July 2001

Protein sets define disease states and predict in vivo effects of drug treatment

scientific article published on 11 April 2013

RsmA regulates Aspergillus fumigatus gliotoxin cluster metabolites including cyclo(L-Phe-L-Ser), a potential new diagnostic marker for invasive aspergillosis ⬇️

scientific article

Scents of adolescence: the maturation of the olfactory phenotype in a free-ranging mammal

scientific article

Selection and gene flow shape niche-associated variation in pheromone response

scientific article published on 23 September 2019

Sex-specific mating pheromones in the nematode Panagrellus redivivus ⬇️

scientific article

Small molecule signaling in Caenorhabditis elegans

scientific article published on May 2006

Small-molecule pheromones that control dauer development in Caenorhabditis elegans

scientific article published on 10 June 2007

Small-molecule signalling: encoding biological information in chemical structures

Spirocyclic lignans from Guaiacum (Zygophyllaceae) induce apoptosis in human breast cancer cell lines ⬇️

scientific article

Steroids as central regulators of organismal development and lifespan

scientific article

Structural characterization of amorfrutins bound to the peroxisome proliferator-activated receptor γ

scientific article

Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans

scientific article published on 20 May 2013

Synthesis and reactivity of [(silox)2Mo=NR]2Hg (R=tBu, tAmyl; silox=OSitBu3): unusual thermal stability and ready nucleophilic cleavage rationalized by electronic factors

scientific article published on 16 October 2007

Synthesis of caeliferins, elicitors of plant immune responses: accessing lipophilic natural products via cross metathesis

scientific article published on 12 October 2011

Synthesis of mayolene-16 and mayolene-18: larval defensive lipids from the European cabbage butterfly

scientific article published on August 2002

Targeted metabolomics reveals a male pheromone and sex-specific ascaroside biosynthesis in Caenorhabditis elegans

scientific article

The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis ⬇️

scholarly article

The psammaplysenes, specific inhibitors of FOXO1a nuclear export

scientific article published in April 2005

Thiamin biosynthesis in eukaryotes: characterization of the enzyme-bound product of thiazole synthase from Saccharomyces cerevisiae and its implications in thiazole biosynthesis

scientific article published in June 2006

Tomato receptor FLAGELLIN-SENSING 3 binds flgII-28 and activates the plant immune system.

scientific article published on 22 August 2016

Transcriptome analysis of cyclic AMP-dependent protein kinase A-regulated genes reveals the production of the novel natural compound fumipyrrole by Aspergillus fumigatus

scientific article published on 11 March 2015

Vitamin B12 produced by gut bacteria modulates cholinergic signalling

scientific article published in January 2024

Vitamin B12 produced by gut bacteria modulates excitatory neurotransmission

scientific article published on 8 September 2022

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