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List of works by Søren Bak

454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides

scientific article

A single oxidosqualene cyclase produces the seco-triterpenoid α-onocerin

scientific article

A tandem array of UDP-glycosyltransferases from the UGT73C subfamily glycosylate sapogenins, forming a spectrum of mono- and bisdesmosidic saponins

scientific article published on 30 March 2018

A web-based resource for the Arabidopsis P450, cytochromes b5, NADPH-cytochrome P450 reductases, and family 1 glycosyltransferases (http://www.P450.kvl.dk)

scientific article published on 08 October 2009

Barbarea vulgaris linkage map and quantitative trait loci for saponins, glucosinolates, hairiness and resistance to the herbivore Phyllotreta nemorum

scientific article

Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants.

scientific article published on 12 August 2013

Biosynthesis of rhodiocyanosides in Lotus japonicus: Rhodiocyanoside A is synthesized from (Z)-2-methylbutanaloxime via 2-methyl-2-butenenitrile

scientific article published in May 2012

Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme

scientific article

Biosynthesis of the nitrile glucosides rhodiocyanoside A and D and the cyanogenic glucosides lotaustralin and linamarin in Lotus japonicus

scientific article

CYP703 is an ancient cytochrome P450 in land plants catalyzing in-chain hydroxylation of lauric acid to provide building blocks for sporopollenin synthesis in pollen

scientific article published on 11 May 2007

CYP79B1 from Sinapis alba converts tryptophan to indole-3-acetaldoxime

scientific article

CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis

scientific article published in September 2003

Cassava plants with a depleted cyanogenic glucoside content in leaves and tubers. Distribution of cyanogenic glucosides, their site of synthesis and transport, and blockage of the biosynthesis by RNA interference technology

scientific article published on 26 August 2005

Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses

scientific article

Chemical defense balanced by sequestration and de novo biosynthesis in a lepidopteran specialist

scientific article

Cloning and expression in Escherichia coli of the obtusifoliol 14 alpha-demethylase of Sorghum bicolor (L.) Moench, a cytochrome P450 orthologous to the sterol 14 alpha-demethylases (CYP51) from fungi and mammals

scientific article

Cloning of three A-type cytochromes P450, CYP71E1, CYP98, and CYP99 from Sorghum bicolor (L.) Moench by a PCR approach and identification by expression in Escherichia coli of CYP71E1 as a multifunctional cytochrome P450 in the biosynthesis of the cy

scientific article published in February 1998

Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast

scientific article published on 23 July 2018

Comparative genomics of rice and Arabidopsis. Analysis of 727 cytochrome P450 genes and pseudogenes from a monocot and a dicot

scientific article published in June 2004

Convergent evolution in biosynthesis of cyanogenic defence compounds in plants and insects

scientific article

Corrigendum: Convergent evolution in biosynthesis of cyanogenic defence compounds in plants and insects

scientific article published on 22 May 2012

Cyanogenesis in Arthropods: From Chemical Warfare to Nuptial Gifts.

scientific article published on 3 May 2018

Cyanogenesis in plants and arthropods

scientific article published on 18 March 2008

Cyanogenic glucosides and plant-insect interactions

scientific article published on February 2004

Cyanogenic glycosides: a case study for evolution and application of cytochromes P450

Cyanogenic glycosides: a case study for evolution and application of cytochromes P450

Cytochromes p450

scientific article (publication date: 2011)

Determination of catalytic key amino acids and UDP sugar donor specificity of the cyanohydrin glycosyltransferase UGT85B1 from Sorghum bicolor. Molecular modeling substantiated by site-specific mutagenesis and biochemical analyses

scientific article published on 16 September 2005

Developmentally Regulated Glucosylation of Bitter Triterpenoid in Cucumber by the UDP-Glucosyltransferase UGT73AM3

scientific article published on 02 March 2017

Diversification of an ancient theme: hydroxynitrile glucosides

scientific article

Effect of glucuronosylation on anthocyanin color stability

scientific article published in April 2009

Evolution of Structural Diversity of Triterpenoids

scientific article published on 17 December 2019

Evolution of heteromeric nitrilase complexes in Poaceae with new functions in nitrile metabolism

scholarly article

Evolution of the Biosynthetic Pathway for Cyanogenic Glucosides in Lepidoptera

scientific article published on 04 July 2018

Glucosinolate turnover in Brassicales species to an oxazolidin-2-one, formed via the 2-thione and without formation of thioamide

scientific article published on 07 June 2018

How insects overcome two-component plant chemical defence: plant β-glucosidases as the main target for herbivore adaptation

scientific article published on August 2014

Identification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana

scientific article published in September 2015

Identification of defense compounds in Barbarea vulgaris against the herbivore Phyllotreta nemorum by an ecometabolomic approach

scientific article

Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol

scientific article published on 28 January 2020

Integrative analysis of metabolomics and transcriptomics data: a unified model framework to identify underlying system pathways

scientific article

Intimate roles for cyanogenic glucosides in the life cycle of Zygaena filipendulae (Lepidoptera, Zygaenidae).

scientific article published on 25 July 2007

Intron-exon organization and phylogeny in a large superfamily, the paralogous cytochrome P450 genes of Arabidopsis thaliana.

scientific article published on May 2000

Isolation and Reconstitution of the Heme-Thiolate Protein Obtusifoliol 14α-Demethylase fromSorghum bicolor(L.) Moench

scientific article published in Journal of Biological Chemistry

Isolation and reconstitution of cytochrome P450ox and in vitro reconstitution of the entire biosynthetic pathway of the cyanogenic glucoside dhurrin from sorghum

scientific article (publication date: December 1997)

Lepidopteran defence droplets - a composite physical and chemical weapon against potential predators

scientific article published on 4 March 2016

Lessons learned from metabolic engineering in hairy roots: Transcriptome and metabolic profile changes caused by Rhizobium-mediated plant transformation in Cucurbitaceae species

scientific article published in 2023

Lessons learned from metabolic engineering of cyanogenic glucosides

article published in 2007

Male-to-female transfer of 5-hydroxytryptophan glucoside during mating in Zygaena filipendulae (Lepidoptera).

scientific article

Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome

scientific article

Metabolic engineering of p-hydroxybenzylglucosinolate in Arabidopsis by expression of the cyanogenic CYP79A1 from Sorghum bicolor

scientific article published in December 1999

Metabolism, excretion and avoidance of cyanogenic glucosides in insects with different feeding specialisations

scientific article published on 16 October 2015

Metabolomic, transcriptional, hormonal, and signaling cross-talk in superroot2.

scientific article

Metabolon formation and metabolic channeling in the biosynthesis of plant natural products

scientific article

Microarray-based analysis of gene expression in very large gene families: the cytochrome P450 gene superfamily of Arabidopsis thaliana

scientific article published in July 2001

Molecular activities, biosynthesis and evolution of triterpenoid saponins ⬇️

scientific article published on February 16, 2011

Multiple hydroxyphenethyl glucosinolate isomers and their tandem mass spectrometric distinction in a geographically structured polymorphism in the crucifer Barbarea vulgaris

scientific article published on 29 September 2014

On the origin of family 1 plant glycosyltransferases

scientific article published in February 2003

Plant Defense against Insect Herbivores

scientific article

Plant P450s as versatile drivers for evolution of species-specific chemical diversity.

scientific article published on 06 January 2013

Plant cytochromes P450: tools for pharmacology, plant protection and phytoremediation

scientific article

Plant cytochromes P450: tools for pharmacology, plant protection and phytoremediation

article

Plant triterpenoids with bond-missing skeletons: biogenesis, distribution and bioactivity

scientific article published on 05 May 2020

Resistance to an herbivore through engineered cyanogenic glucoside synthesis.

scientific article published on 26 July 2001

Response to Kutchan: Genetic engineering, natural variation and substantial equivalence

Screening for Triterpenoid Saponins in Plants Using Hyphenated Analytical Platforms

scientific article published on 24 November 2016

Sequestration and biosynthesis of cyanogenic glucosides in passion vine butterflies and consequences for the diversification of their host plants

article

Sequestration, tissue distribution and developmental transmission of cyanogenic glucosides in a specialist insect herbivore

scientific article published on 21 November 2013

Spatial separation of the cyanogenic β-glucosidase ZfBGD2 and cyanogenic glucosides in the haemolymph of Zygaena larvae facilitates cyanide release

scientific article

Spot shape modelling and data transformations for microarrays

scientific article

Substrate specificity of plant UDP-dependent glycosyltransferases predicted from crystal structures and homology modeling

scientific article published on 13 February 2009

The TriForC database: a comprehensive up-to-date resource of plant triterpene biosynthesis.

scientific article published on 17 October 2017

The arms race between heliconiine butterflies and Passiflora plants - new insights on an ancient subject

scientific article published on 13 September 2017

The beta-glucosidases responsible for bioactivation of hydroxynitrile glucosides in Lotus japonicus

scientific article published on 8 May 2008

The bifurcation of the cyanogenic glucoside and glucosinolate biosynthetic pathways

scientific article published on 01 November 2015

The cyanogenic glucoside composition of Zygaena filipendulae (Lepidoptera: Zygaenidae) as effected by feeding on wild-type and transgenic lotus populations with variable cyanogenic glucoside profiles

scientific article published on 4 October 2006

The cytochrome P450 CYP72A552 is key to production of hederagenin-based saponins that mediate plant defense against herbivores

scientific article published on 25 February 2019

The dynamics of cyanide defences in the life cycle of an aposematic butterfly: Biosynthesis versus sequestration

scientific article published on 04 November 2019

The genome sequence of Barbarea vulgaris facilitates the study of ecological biochemistry.

scientific article

The in vitro substrate regiospecificity of recombinant UGT85B1, the cyanohydrin glucosyltransferase from Sorghum bicolor

scientific article

The multiple strategies of an insect herbivore to overcome plant cyanogenic glucoside defence

scientific article (publication date: 2014)

The presence of CYP79 homologues in glucosinolate-producing plants shows evolutionary conservation of the enzymes in the conversion of amino acid to aldoxime in the biosynthesis of cyanogenic glucosides and glucosinolates

scientific article published in November 1998

The use of trimethylsilyl cyanide derivatization for robust and broad-spectrum high-throughput gas chromatography–mass spectrometry based metabolomics

Transcriptional regulation of de novo biosynthesis of cyanogenic glucosides throughout the life-cycle of the burnet moth Zygaena filipendulae (Lepidoptera).

scientific article published on 13 April 2014

Triterpene Messages from the EU-FP7 Project TriForC.

scientific article published on 23 February 2018

UDP-glycosyltransferases from the UGT73C subfamily in Barbarea vulgaris catalyze sapogenin 3-O-glucosylation in saponin-mediated insect resistance

scientific article

Visualizing metabolite distribution and enzymatic conversion in plant tissues by desorption electrospray ionization mass spectrometry imaging

scientific article published on 6 May 2013

Volatiles from the burnet mothZygaena filipendulae(Lepidoptera) and associated flowers, and their involvement in mating communication

scholarly article by Mika Zagrobelny et al published 28 August 2015 in Physiological Entomology

beta-Glucosidases as detonators of plant chemical defense

scientific article published on 09 May 2008

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