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List of works by Thomas Pulinilkunnil

A lysosome independent role for TFEB in activating DNA repair and inhibiting apoptosis in breast cancer cells

scientific article published on 01 January 2020

AMPK control of myocardial fatty acid metabolism fluctuates with the intensity of insulin-deficient diabetes.

scientific article published on 26 December 2006

AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice.

scientific article

AMPK-dependent inhibitory phosphorylation of ACC is not essential for maintaining myocardial fatty acid oxidation.

scientific article

Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling

scientific article published on 31 August 2009

Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice

scientific article published on 17 March 2015

Altered cardiac fatty acid composition and utilization following dexamethasone-induced insulin resistance

scientific article published on 11 April 2006

Autophagic dysregulation in doxorubicin cardiomyopathy.

scientific article published on 17 January 2017

Autotaxin Is Regulated by Glucose and Insulin in Adipocytes

scientific article published on 16 January 2017

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism

scientific article published on 02 August 2018

Branched-chain ketoacid overload inhibits insulin action in the muscle

scientific article published on 02 September 2020

Brief episode of STZ-induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n-6 PUFA.

scientific article

Cardiac complications of congenital disorders of glycosylation (CDG): a systematic review of the literature

scientific article

Cardiac glycogen accumulation after dexamethasone is regulated by AMPK.

scientific article published on 29 August 2008

Cardiac lipoprotein lipase: metabolic basis for diabetic heart disease.

scientific article

Cardiac triglyceride accumulation following acute lipid excess occurs through activation of a FoxO1-iNOS-CD36 pathway

scientific article published on 13 April 2011

Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity.

scientific article published on 5 June 2013

Cardiomyocyte apoptosis induced by short-term diabetes requires mitochondrial GSH depletion

scientific article

Cardiomyocyte specific adipose triglyceride lipase overexpression prevents doxorubicin induced cardiac dysfunction in female mice.

scientific article published on 23 May 2013

Cardiomyocyte-specific ablation of CD36 improves post-ischemic functional recovery.

scientific article published on 12 August 2013

Changes in Circulating Monocyte Subsets (CD16 Expression) and Neutrophil-to-Lymphocyte Ratio Observed in Patients Undergoing Cardiac Surgery

scientific article published on 15 March 2017

Circulating triglyceride lipolysis facilitates lipoprotein lipase translocation from cardiomyocyte to myocardial endothelial lining

scientific article published in September 2003

Dieldrin Augments mTOR Signaling and Regulates Genes Associated with Cardiovascular Disease in the Adult Zebrafish Heart (Danio rerio).

scientific article published on 6 April 2017

Direct regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock.

scientific article

Distinct early signaling events resulting from the expression of the PRKAG2 R302Q mutant of AMPK contribute to increased myocardial glycogen.

scientific article published on 15 July 2009

Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy

scientific article published on 03 August 2016

Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation

scientific article published on 25 May 2013

Evidence for rapid "metabolic switching" through lipoprotein lipase occupation of endothelial-binding sites

scientific article published in September 2003

Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes

scientific article published on 9 September 2016

Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes

scientific article published on 7 October 2016

Holiday reading. Diving into the ice bucket challenge.

scientific article published on December 2014

Impact of Obesity on Postoperative Outcomes following cardiac Surgery (The OPOS study): rationale and design of an investigator-initiated prospective study

scientific article published on 03 March 2019

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice

scientific article

Increased efflux of glutathione conjugate in acutely diabetic cardiomyocytes

scientific article published in October 2004

Induction of mitochondrial nitrative damage and cardiac dysfunction by chronic provision of dietary omega-6 polyunsaturated fatty acids.

scientific article

Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.

scientific article

Ischemia-reperfusion alters cardiac lipoprotein lipase.

scientific article published on 24 October 2009

Lysophosphatidic acid receptor mRNA levels in heart and white adipose tissue are associated with obesity in mice and humans.

scientific article published on 13 December 2017

Lysophosphatidic acid-mediated augmentation of cardiomyocyte lipoprotein lipase involves actin cytoskeleton reorganization.

scientific article

Lysosomal Biology and Function: Modern View of Cellular Debris Bin

scientific article published on 04 May 2020

Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3.

scientific article

Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction

scientific article published on 12 December 2011

Myocardial adipose triglyceride lipase overexpression protects diabetic mice from the development of lipotoxic cardiomyopathy

scientific article published on 24 January 2013

Myocardial triacylglycerol metabolism.

scientific article published on 10 July 2012

Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues

scientific article published on 15 June 2009

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

scientific article

Palmitoyl lysophosphatidylcholine mediated mobilization of LPL to the coronary luminal surface requires PKC activation.

scientific article published on November 2004

Role of branched-chain amino acid-catabolizing enzymes in intertissue signaling, metabolic remodeling, and energy homeostasis

scientific article published on 14 May 2019

Role of dietary fatty acids and acute hyperglycemia in modulating cardiac cell death

scientific article published in October 2004

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.

scientific article

Single-dose dexamethasone induces whole-body insulin resistance and alters both cardiac fatty acid and carbohydrate metabolism

scientific article

Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise.

scientific article published on July 2015

Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity

scientific article published on 08 July 2013

The MiTF/TFE Family of Transcription Factors: Master Regulators of Organelle Signaling, Metabolism and Stress Adaptation.

scientific article published on 29 August 2017

The metabolic "switch" AMPK regulates cardiac heparin-releasable lipoprotein lipase

scientific article

The role of ubiquitin ligases in cardiac disease.

scientific article

Validation of optimal reference genes for quantitative real time PCR in muscle and adipose tissue for obesity and diabetes research

scientific article

Whey Peptides Stimulate Differentiation and Lipid Metabolism in Adipocytes and Ameliorate Lipotoxicity-Induced Insulin Resistance in Muscle Cells

scientific article published on 06 February 2020

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