List of works - Salvatore La Rosa

A high-throughput molecular data resource for cutaneous neurofibromas.

scientific article

A prototype solid phase synthesis of pteridines and related heterocyclic compounds

scientific article published in June 2003

A traceless solid-phase synthesis of pteridines

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

scientific article published on 15 July 2021

Creating a data resource: what will it take to build a medical information commons?

scientific article published on 22 September 2017

Cutaneous neurofibromas in the genomics era: current understanding and open questions

scientific article published on 26 April 2018

Drug discovery and development for Huntington's disease - an orphan indication with high medical need.

scientific article published on September 2008

Efficient Synthesis of 3,5-Dicarbamoyl-1,4-dihydropyridines from Pyridinium Salts: Key Molecules in Understanding NAD(P)+/NAD(P)H Pathways

Engaging a community to enable disease-centric data sharing with the NF Data Portal

scientific article published on 13 December 2019

Funding community collaboration to develop effective therapies for neurofibromatosis type 1 tumors

scientific article published on 02 December 2019

Fused 3-Hydroxy-3-trifluoromethylpyrazoles Inhibit Mutant Huntingtin Toxicity

scientific article

Neurofibromatosis as a gateway to better treatment for a variety of malignancies

scientific article published on 4 February 2016

Novel Hits in the Correction of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3-d]pyrimidines for the Potential Treatment of Cystic Fibrosis.

scientific article published on 11 November 2015

Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN3462

scientific article published in June 2010

Probing the chemical-biological relationship space with the Drug Target Explorer

Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery.

scientific article

Rethinking the nonprofit foundation: an emerging niche in the rare disease ecosystem.

scientific article published on 25 July 2017

The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin

scientific article published on 20 May 2019

The synthesis of 7-deazaguanines as potential inhibitors of guanosine triphosphate cyclohydrolase I

Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2.

scientific article

List of works by Salvatore La Rosa

A high-throughput molecular data resource for cutaneous neurofibromas.

A prototype solid phase synthesis of pteridines and related heterocyclic compounds

A traceless solid-phase synthesis of pteridines

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

Creating a data resource: what will it take to build a medical information commons?

Cutaneous neurofibromas in the genomics era: current understanding and open questions

Drug discovery and development for Huntington's disease - an orphan indication with high medical need.

Efficient Synthesis of 3,5-Dicarbamoyl-1,4-dihydropyridines from Pyridinium Salts: Key Molecules in Understanding NAD(P)+/NAD(P)H Pathways

Engaging a community to enable disease-centric data sharing with the NF Data Portal

Funding community collaboration to develop effective therapies for neurofibromatosis type 1 tumors

Fused 3-Hydroxy-3-trifluoromethylpyrazoles Inhibit Mutant Huntingtin Toxicity

Neurofibromatosis as a gateway to better treatment for a variety of malignancies

Novel Hits in the Correction of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3-d]pyrimidines for the Potential Treatment of Cystic Fibrosis.

Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN3462

Probing the chemical-biological relationship space with the Drug Target Explorer

Probing the chemical-biological relationship space with the Drug Target Explorer

Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery.

Rethinking the nonprofit foundation: an emerging niche in the rare disease ecosystem.

The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin

The synthesis of 7-deazaguanines as potential inhibitors of guanosine triphosphate cyclohydrolase I

Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2.