List of works - Sara J Brown

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

scientific article published on 25 July 2013

Are filaggrin mutations associated with hand eczema or contact allergy? – we do not know

scientific article published on 02 April 2008

Atopic Eczema: How Genetic Studies Can Contribute to the Understanding of this Complex Trait

scientific article published in 2022

Atopic and non-atopic eczema

scientific article

Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

scientific article

Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations

scientific article

Chronic cutaneous graft-versus-host disease associated with multiple cutaneous squamous cell carcinomas

scientific article published on 01 May 2006

Coma blisters in 2 children on anticonvulsant medication

scientific article

Eczema genetics: current state of knowledge and future goals

scientific article published on March 2009

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention

scientific article

Emollients for prevention of atopic dermatitis: 5‐year findings from the <scp>BEEP</scp> randomized trial

scientific article published in 2022

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

scientific article published on 31 January 2019

Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status

scientific article published on 16 May 2013

Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.

scientific article

Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease

scientific article published in October 2009

Filaggrin null mutations and childhood atopic eczema: A population-based case-control study

article

Filaggrin null mutations are not a protective factor for acne vulgaris.

scientific article

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

scientific article

Functional and proteomic analysis of a full thickness filaggrin-deficient skin organoid model

scientific article published on 26 November 2019

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

scientific article

Hand dermatitis in construction workers: a lesson in genetic epidemiology

scientific article

Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma.

scientific article published on 14 October 2012

Heterozygous mutations in AAGAB cause type 1 punctate palmoplantar keratoderma with evidence for increased growth factor signaling

scientific article published on 6 June 2013

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

scientific article published on 02 June 2013

Identification of translational dermatology research priorities in the U.K.: results of an electronic Delphi exercise

scientific article published on 06 July 2015

Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-Seq and ESTs.

scientific article

Insight from the Air–Skin Interface

scientific article published on 01 February 2015

Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect

scientific article published on 10 November 2011

Investigating the causal relationship between allergic disease and mental health

scientific article published in 2021

Loss-of-Function Mutations in the Gene Encoding Filaggrin Are Not Strongly Associated with Chronic Actinic Dermatitis

article

Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy.

scientific article

Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease

scientific article published on 01 June 2009

Mutations in the SASPase gene (ASPRV1) are not associated with atopic eczema or clinically dry skin

scientific article

One Remarkable Molecule: Filaggrin ⬇️

scientific article published on December 8, 2011

Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations

scientific article

Prevalent and Low-Frequency Null Mutations in the Filaggrin Gene Are Associated with Early-Onset and Persistent Atopic Eczema

article

Propranolol in the treatment of infantile haemangiomas: lessons from the European Propranolol In the Treatment of Complicated Haemangiomas (PITCH) Taskforce survey.

scientific article

Pseudoxanthoma elasticum: biopsy of clinically normal skin in the investigation of patients with angioid streaks

scientific article published on 30 July 2007

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

scientific article published on 16 November 2021

Silk garments plus standard care compared with standard care for treating eczema in children: A randomised, controlled, observer-blind, pragmatic trial (CLOTHES Trial).

scientific article

South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin

scientific article published on January 2014

Subcorneal pustular dermatosis in association with chronic lymphocytic leukaemia

scientific article published in January 2003

The Microevolution and Epidemiology of Staphylococcus aureus Colonization during Atopic Eczema Disease Flare.

scientific article

The Pharmacogenetics of Body Odor: As Easy as ABCC? ⬇️

scientific article published on July 1, 2013

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

scientific journal article

Translational genetics: a challenging but important path

scientific article published on 16 November 2020

What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review

scientific article published on 03 December 2019

Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations.

scientific article

List of works by Sara J Brown

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

Are filaggrin mutations associated with hand eczema or contact allergy? – we do not know

Atopic Eczema: How Genetic Studies Can Contribute to the Understanding of this Complex Trait

Atopic and non-atopic eczema

Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations

Chronic cutaneous graft-versus-host disease associated with multiple cutaneous squamous cell carcinomas

Coma blisters in 2 children on anticonvulsant medication

Eczema genetics: current state of knowledge and future goals

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention

Emollients for prevention of atopic dermatitis: 5‐year findings from the <scp>BEEP</scp> randomized trial

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status

Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.

Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease

Filaggrin null mutations and childhood atopic eczema: A population-based case-control study

Filaggrin null mutations are not a protective factor for acne vulgaris.

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

Functional and proteomic analysis of a full thickness filaggrin-deficient skin organoid model

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

Hand dermatitis in construction workers: a lesson in genetic epidemiology

Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma.

Heterozygous mutations in AAGAB cause type 1 punctate palmoplantar keratoderma with evidence for increased growth factor signaling

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

Identification of translational dermatology research priorities in the U.K.: results of an electronic Delphi exercise

Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-Seq and ESTs.

Insight from the Air–Skin Interface

Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect

Investigating the causal relationship between allergic disease and mental health

Loss-of-Function Mutations in the Gene Encoding Filaggrin Are Not Strongly Associated with Chronic Actinic Dermatitis

Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy.

Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease

Mutations in the SASPase gene (ASPRV1) are not associated with atopic eczema or clinically dry skin

One Remarkable Molecule: Filaggrin ⬇️

Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations

Prevalent and Low-Frequency Null Mutations in the Filaggrin Gene Are Associated with Early-Onset and Persistent Atopic Eczema

Propranolol in the treatment of infantile haemangiomas: lessons from the European Propranolol In the Treatment of Complicated Haemangiomas (PITCH) Taskforce survey.

Pseudoxanthoma elasticum: biopsy of clinically normal skin in the investigation of patients with angioid streaks

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

Silk garments plus standard care compared with standard care for treating eczema in children: A randomised, controlled, observer-blind, pragmatic trial (CLOTHES Trial).

South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin

Subcorneal pustular dermatosis in association with chronic lymphocytic leukaemia

The Microevolution and Epidemiology of Staphylococcus aureus Colonization during Atopic Eczema Disease Flare.

The Pharmacogenetics of Body Odor: As Easy as ABCC? ⬇️

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

Translational genetics: a challenging but important path

What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review

Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations.