List of works - Pamela Zeitlin

A multicenter study of the effect of solution temperature on nasal potential difference measurements

scientific article published in August 2003

A phase I trial of intranasal Moli1901 for cystic fibrosis

scientific article

A simplified cyclic adenosine monophosphate-mediated sweat rate test for quantitative measure of cystic fibrosis transmembrane regulator (CFTR) function

scientific article published in December 2000

Acidic pH hyperpolarizes nasal potential difference

scientific article published in February 2006

Advances in the diagnosis of cystic fibrosis in infants

scientific article published on 01 September 2001

Alternative mRNA splice variants of the rat ClC-2 chloride channel gene are expressed in lung: genomic sequence and organization of ClC-2 ⬇️

scientific article published on October 15, 1997

Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells.

scientific article

Antibody Microarrays: Analysis of Cystic Fibrosis

article

Applications of proteomic technologies for understanding the premature proteolysis of CFTR.

scientific article

Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial

scientific article

Atypical cystic fibrosis and CFTR-related diseases.

scientific article published on December 2008

Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.

scientific article

CHOP transcription factor mediates IL-8 signaling in cystic fibrosis bronchial epithelial cells.

scientific article published on 20 August 2007

Can curcumin cure cystic fibrosis?

scientific article

Chemical rescue of deltaF508-CFTR mimics genetic repair in cystic fibrosis bronchial epithelial cells.

scientific article published on 19 February 2008

Clinical Phenotypes and Genotypic Spectrum of Cystic Fibrosis in Chinese Children.

scientific article published on 27 January 2016

Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapy

scientific article

Current treatment recommendations for correcting vitamin D deficiency in pediatric patients with cystic fibrosis are inadequate

scientific article published on 27 June 2008

Cystic fibrosis

scientific article published on 01 January 1998

Cystic fibrosis and estrogens: a perfect storm

scientific article published on 20 November 2008

Cystic fibrosis and sinusitis in children: outcomes and socioeconomic status

scientific article

Cystic fibrosis gene therapy trials and tribulations

scientific article published in January 2000

Cystic fibrosis presenting as recurrent pancreatitis in a young child with a normal sweat test and pancreas divisum: a case report.

scientific article

De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells

scientific article published on 7 July 2006

Description of a Standardized Nutrition Classification Plan and its Relation to Nutritional Outcomes in Children with Cystic Fibrosis

scientific article published on 06 May 2009

Dietary supplement use in pediatric patients with cystic fibrosis.

scientific article

Digitoxin for Airway Inflammation in Cystic Fibrosis: Preliminary Assessment of Safety, Pharmacokinetics, and Dose Finding.

scientific article published on 22 December 2016

Direct interactions between ENaC gamma subunit and ClCN2 in cystic fibrosis epithelial cells

scientific article

Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia

scientific article published on 11 January 2013

Duration of treatment effect after tobramycin solution for inhalation in young children with cystic fibrosis

scholarly article by Ronald L. Gibson et al published 2007 in Pediatric Pulmonology

Effect of adeno-associated virus-specific immunoglobulin G in human amniotic fluid on gene transfer.

scientific article published on March 2003

Elevated Serum IL-8 Levels in Ataxia Telangiectasia

scientific article published on 20 February 2010

Evaluation of exposure and health care worker response to nebulized administration of tgAAVCF to patients with cystic fibrosis

scientific article published on 26 October 2004

Evidence of CFTR function in cystic fibrosis after systemic administration of 4-phenylbutyrate

scientific article

Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins ⬇️

scientific article published on January 15, 2004

Gene transfer by lipofection in rabbit and human secretory epithelial cells.

scientific article

Inflammatory and microbiologic markers in induced sputum after intravenous antibiotics in cystic fibrosis

scientific article published on 11 September 2003

Interference with ubiquitination in CFTR modifies stability of core glycosylated and cell surface pools.

scientific article published on July 2014

Is it go or NO go for S-nitrosylation modification-based therapies of cystic fibrosis transmembrane regulator trafficking?

scientific article published on 28 July 2006

Levofloxacin pharmacokinetics in adult cystic fibrosis

scientific article

Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice.

scientific article published on 19 September 2008

Modulation of Sp1 and Sp3 in lung epithelial cells regulates ClC-2 chloride channel expression.

scientific article published on 24 April 2003

Modulation of deltaF508 cystic fibrosis transmembrane regulator trafficking and function with 4-phenylbutyrate and flavonoids

scientific article

N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles.

scientific article published on 9 August 2011

NHLBI training workshop report: The vanishing pediatric pulmonary investigator and recommendations for recovery

scientific article published in January 2010

NHLBI training workshop report: the vanishing pediatric pulmonary investigator and recommendations for recovery

scientific article published on 6 October 2009

Patients with Mutations in Gsα Have Reduced Activation of a Downstream Target in Epithelial Tissues due to Haploinsufficiency

scientific article published on 24 July 2007

Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR.

scientific article published on 13 February 2017

Pharmacologic restoration of delta F508 CFTR-mediated chloride current.

scientific article

Pharmacoproteomics of 4-phenylbutyrate-treated IB3-1 cystic fibrosis bronchial epithelial cells.

scientific article published on March 2006

Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study

scientific article published in July 2003

Protein microarray platforms for clinical proteomics.

scientific article published on 10 August 2007

Protein processing and degradation in pulmonary health and disease.

scientific article published on November 2003

Pseudomonas aeruginosa: can studies in engineered cells tell us why is it such a problem in people with cystic fibrosis? Focus on "Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudom

scientific article

Pulmonary function in adolescents with ataxia telangiectasia

scientific article published in January 2008

Randomized, double-blind, placebo-controlled, dose-escalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease

scientific article

Recurrent and destructive nasal polyposis in 2 siblings: a possible case of Woakes' syndrome.

scientific article

Regulation of the ClC-2 lung epithelial chloride channel by glycosylation of SP1.

scientific article published on 2 February 2006

Repeated Aerosolized AAV-CFTR for Treatment of Cystic Fibrosis: A Randomized Placebo-Controlled Phase 2B Trial

article

Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial

scientific article published in February 2004

Respiratory epithelial gene expression in patients with mild and severe cystic fibrosis lung disease.

scientific article published on 13 April 2006

Safety and tolerability of denufosol tetrasodium inhalation solution, a novel P2Y2 receptor agonist: results of a phase 1/phase 2 multicenter study in mild to moderate cystic fibrosis

scientific article published in April 2005

Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels: therapeutic implications

scientific article

Serum proteomic signature for cystic fibrosis using an antibody microarray platform

scientific article published on 10 January 2006

Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis

scientific article published on 12 December 2002

THERAPIES DIRECTED AT THE BASIC DEFECT IN CYSTIC FIBROSIS

article

Targeting aerosol deposition in patients with cystic fibrosis: effects of alterations in particle size and inspiratory flow rate

scientific article published in October 2000

The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.

scientific article published on 26 January 2009

Therapeutic approaches to repair defects in deltaF508 CFTR folding and cellular targeting.

scientific article

Transient effectiveness of vitamin D2 therapy in pediatric cystic fibrosis patients

scientific article published on 08 February 2010

Use of protein repair therapy in the treatment of cystic fibrosis ⬇️

scientific article published on June 1, 1998

Variant cystic fibrosis phenotypes in the absence of CFTR mutations

scientific article published in August 2002

“Bronchitis” obliterans and prolonged transient hypogammaglobulinemia in a child

article

List of works by Pamela Zeitlin

A multicenter study of the effect of solution temperature on nasal potential difference measurements

A phase I trial of intranasal Moli1901 for cystic fibrosis

A simplified cyclic adenosine monophosphate-mediated sweat rate test for quantitative measure of cystic fibrosis transmembrane regulator (CFTR) function

Acidic pH hyperpolarizes nasal potential difference

Advances in the diagnosis of cystic fibrosis in infants

Alternative mRNA splice variants of the rat ClC-2 chloride channel gene are expressed in lung: genomic sequence and organization of ClC-2 ⬇️

Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells.

Antibody Microarrays: Analysis of Cystic Fibrosis

Applications of proteomic technologies for understanding the premature proteolysis of CFTR.

Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial

Atypical cystic fibrosis and CFTR-related diseases.

Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.

CHOP transcription factor mediates IL-8 signaling in cystic fibrosis bronchial epithelial cells.

Can curcumin cure cystic fibrosis?

Chemical rescue of deltaF508-CFTR mimics genetic repair in cystic fibrosis bronchial epithelial cells.

Clinical Phenotypes and Genotypic Spectrum of Cystic Fibrosis in Chinese Children.

Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapy

Current treatment recommendations for correcting vitamin D deficiency in pediatric patients with cystic fibrosis are inadequate

Cystic fibrosis

Cystic fibrosis and estrogens: a perfect storm

Cystic fibrosis and sinusitis in children: outcomes and socioeconomic status

Cystic fibrosis gene therapy trials and tribulations

Cystic fibrosis presenting as recurrent pancreatitis in a young child with a normal sweat test and pancreas divisum: a case report.

De novo biosynthetic profiling of high abundance proteins in cystic fibrosis lung epithelial cells

Description of a Standardized Nutrition Classification Plan and its Relation to Nutritional Outcomes in Children with Cystic Fibrosis

Dietary supplement use in pediatric patients with cystic fibrosis.

Digitoxin for Airway Inflammation in Cystic Fibrosis: Preliminary Assessment of Safety, Pharmacokinetics, and Dose Finding.

Direct interactions between ENaC gamma subunit and ClCN2 in cystic fibrosis epithelial cells

Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia

Duration of treatment effect after tobramycin solution for inhalation in young children with cystic fibrosis

Effect of adeno-associated virus-specific immunoglobulin G in human amniotic fluid on gene transfer.

Elevated Serum IL-8 Levels in Ataxia Telangiectasia

Evaluation of exposure and health care worker response to nebulized administration of tgAAVCF to patients with cystic fibrosis

Evidence of CFTR function in cystic fibrosis after systemic administration of 4-phenylbutyrate

Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins ⬇️

Gene transfer by lipofection in rabbit and human secretory epithelial cells.

Inflammatory and microbiologic markers in induced sputum after intravenous antibiotics in cystic fibrosis

Interference with ubiquitination in CFTR modifies stability of core glycosylated and cell surface pools.

Is it go or NO go for S-nitrosylation modification-based therapies of cystic fibrosis transmembrane regulator trafficking?

Levofloxacin pharmacokinetics in adult cystic fibrosis

Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice.

Modulation of Sp1 and Sp3 in lung epithelial cells regulates ClC-2 chloride channel expression.

Modulation of deltaF508 cystic fibrosis transmembrane regulator trafficking and function with 4-phenylbutyrate and flavonoids

N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles.

NHLBI training workshop report: The vanishing pediatric pulmonary investigator and recommendations for recovery

NHLBI training workshop report: the vanishing pediatric pulmonary investigator and recommendations for recovery

Patients with Mutations in Gsα Have Reduced Activation of a Downstream Target in Epithelial Tissues due to Haploinsufficiency

Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR.

Pharmacologic restoration of delta F508 CFTR-mediated chloride current.

Pharmacoproteomics of 4-phenylbutyrate-treated IB3-1 cystic fibrosis bronchial epithelial cells.

Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study

Protein microarray platforms for clinical proteomics.

Protein processing and degradation in pulmonary health and disease.

Pseudomonas aeruginosa: can studies in engineered cells tell us why is it such a problem in people with cystic fibrosis? Focus on "Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudom

Pulmonary function in adolescents with ataxia telangiectasia

Randomized, double-blind, placebo-controlled, dose-escalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease

Recurrent and destructive nasal polyposis in 2 siblings: a possible case of Woakes' syndrome.

Regulation of the ClC-2 lung epithelial chloride channel by glycosylation of SP1.

Repeated Aerosolized AAV-CFTR for Treatment of Cystic Fibrosis: A Randomized Placebo-Controlled Phase 2B Trial

Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial

Respiratory epithelial gene expression in patients with mild and severe cystic fibrosis lung disease.

Safety and tolerability of denufosol tetrasodium inhalation solution, a novel P2Y2 receptor agonist: results of a phase 1/phase 2 multicenter study in mild to moderate cystic fibrosis

Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels: therapeutic implications

Serum proteomic signature for cystic fibrosis using an antibody microarray platform

Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis

THERAPIES DIRECTED AT THE BASIC DEFECT IN CYSTIC FIBROSIS

Targeting aerosol deposition in patients with cystic fibrosis: effects of alterations in particle size and inspiratory flow rate

The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.

Therapeutic approaches to repair defects in deltaF508 CFTR folding and cellular targeting.

Transient effectiveness of vitamin D2 therapy in pediatric cystic fibrosis patients

Use of protein repair therapy in the treatment of cystic fibrosis ⬇️

Variant cystic fibrosis phenotypes in the absence of CFTR mutations

“Bronchitis” obliterans and prolonged transient hypogammaglobulinemia in a child