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List of works by Binghe Wang

14-3-3zeta binds a phosphorylated Raf peptide and an unphosphorylated peptide via its conserved amphipathic groove

scientific article

4-Iminooxazolidin-2-one as a Bioisostere of the Cyanohydrin Moiety: Inhibitors of Enterovirus 71 3C Protease

scientific article published on 08 November 2018

A Fluorescent Hydrogen Peroxide Probe Based on a 'Click' Modified Coumarin Fluorophore

scientific article

A Redox-Sensitive Resin Linker for the Solid Phase Synthesis of C-Terminal Modified Peptides ⬇️

scientific article published on January 8, 1999

A comparison of different electrostatic potentials on prediction accuracy in CoMFA and CoMSIA studies

A fast and simple approach to the quantitative evaluation of fibrinogen coagulation

scientific article published on 8 October 2013

A fluorescent bisboronic acid compound that selectively labels cells expressing oligosaccharide Lewis X.

scientific article published on 28 April 2015

A fluorescent probe for fast and quantitative detection of hydrogen sulfide in blood.

scientific article published on 31 August 2011

A fluorescent probe for rapid aqueous fluoride detection and cell imaging

scientific article published on March 2013

A highly selective and sensitive fluorescent probe for simultaneously distinguishing and sequentially detecting HS and various thiol species in solution and in live cells

scientific article published on 01 November 2018

A metal-free turn-on fluorescent probe for the fast and sensitive detection of inorganic azides

scientific article published on 23 February 2016

A new boronic acid based fluorescent reporter for catechol

article

A new boronic acid fluorescent reporter that changes emission intensities at three wavelengths upon sugar binding

article by Junfeng Wang et al published October 2005 in Tetrahedron Letters

A new class of fluorescent boronic acids that have extraordinarily high affinities for diols in aqueous solution at physiological pH

scientific article published on December 2010

A new data mining tool for analyzing coumarin-based prodrugs

A new phenothiazine structural scaffold as inhibitors of bacterial quorum sensing in Vibrio harveyi

scientific article published on 4 March 2009

A new type of boronic acid fluorescent reporter compound for sugar recognition

article by Wenqian Yang et al published November 2005 in Tetrahedron Letters

A unique quinolineboronic acid-based supramolecular structure that relies on double intermolecular B-N bonds for self-assembly in solid state and in solution.

scientific article

Amiloride Analogs as ASIC1a Inhibitors

scientific article published on 18 February 2016

An esterase-activated click and release approach to metal-free CO-prodrugs

scientific article

An unexpected copper catalyzed 'reduction' of an arylazide to amine through the formation of a nitrene intermediate

scientific article published on June 2013

Arylboronic acids with strong fluorescence intensity changes upon sugar binding

article by Sarah Laughlin et al published 1 January 2012 in Heterocyclic Communications

Arylsulfonamide 64B Inhibits Hypoxia/HIF-Induced Expression of c-Met and CXCR4 and Reduces Primary Tumor Growth and Metastasis of Uveal Melanoma

scientific article published on 18 December 2018

Biomarker-Based Metabolic Labeling for Redirected and Enhanced Immune Response

scientific article published on 01 June 2018

Biphasic actions of SecA inhibitors on Prl/Sec suppressors: Possible physiological roles of SecA-only channels

scientific article published on 14 November 2016

Boronic Acid-Based Lectin Mimics (Boronolectins) That Can Recognize Cancer Biomarker, the Thomsen-Friedenrich Antigen

scientific article published on 01 November 2010

CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt ⬇️

scientific article published on April 10, 2012

Carbohydrate biomarkers for future disease detection and treatment

scientific article published on 07 February 2010

Carbohydrate recognition by boronolectins, small molecules, and lectins

scientific article

Carbon monoxide: An emerging therapy for acute kidney injury

scientific article published on 09 December 2019

Chemical validation of phosphodiesterase C as a chemotherapeutic target in Trypanosoma cruzi, the etiological agent of Chagas' disease

scientific article published on 12 July 2010

Click and Fluoresce: A Bioorthogonally Activated Smart Probe for Wash-Free Fluorescent Labeling of Biomolecules

scientific article published on 9 January 2017

Click and Release: A Chemical Strategy toward Developing Gasotransmitter Prodrugs by Using an Intramolecular Diels-Alder Reaction

scientific article published on 23 November 2016

Click and Release: A High-Content Bioorthogonal Prodrug with Multiple Outputs

scientific article published on 07 May 2019

Click and Release: SO2 Prodrugs with Tunable Release Rates.

scientific article

Click and release: bioorthogonal approaches to "on-demand" activation of prodrugs

scientific article published on 01 February 2019

Click reactions and boronic acids: applications, issues, and potential solutions.

scientific article published on 23 August 2010

Click, Release, and Fluoresce: A Chemical Strategy for a Cascade Prodrug System for Codelivery of Carbon Monoxide, a Drug Payload, and a Fluorescent Reporter

scientific article published on 30 January 2018

Commentary on Perrone et al.: 'vitamin C: not for breakfast anymore...if you have myeloma'.

scientific article published in November 2009

Computational studies of H5N1 hemagglutinin binding with SA-α-2, 3-Gal and SA-α-2, 6-Gal

scientific article published in 2006

Computational studies of the binding site of alpha1A-adrenoceptor antagonists

scientific article published on 15 July 2008

Computer-based de novo design, synthesis, and evaluation of boronic acid-based artificial receptors for selective recognition of dopamine

scientific article

Corrigendum to “A unique quinolineboronic acid-based supramolecular structure that relies on double intermolecular B–N bonds for self-assembly in solid state and in solution”

scholarly article published in Tetrahedron

Coumarin-based prodrugs 2. Synthesis and bioreversibility studies of an esterase-sensitive cyclic prodrug of dadle, an opioid peptide

scientific article published in 1996

Design and synthesis of benzopyran-based inhibitors of the hypoxia-inducible factor-1 pathway with improved water solubility.

scientific article published in December 2017

Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA

Design and synthesis of boronic-acid-labeled thymidine triphosphate for incorporation into DNA.

scientific article

Design and synthesis of novel chloramphenicol amine derivatives as potent aminopeptidase N (APN/CD13) inhibitors.

scientific article published on 24 April 2009

Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway

scientific article published on 23 November 2011

Design, Synthesis and Evaluation of Triazole-Pyrimidine Analogues as SecA Inhibitors.

scientific article published on 26 November 2015

Design, Synthesis, and Antitumor Evaluation of 4-Amino-(1H)-pyrazole Derivatives as JAKs Inhibitors

scientific article published on 23 August 2016

Design, Synthesis, and Biological Evaluation of Pyrazoline-Based Hydroxamic Acid Derivatives as Aminopeptidase N (APN) Inhibitors.

scientific article published on 27 January 2018

Design, syntheses and evaluation of 4-oxo-5-cyano thiouracils as SecA inhibitors

scientific article published on 20 November 2014

Design, synthesis and antibacterial activities of thiouracil derivatives containing acyl thiourea as SecA inhibitors

scientific article published on 23 November 2016

Design, synthesis and antimicrobial activities of thiouracil derivatives containing triazolo-thiadiazole as SecA inhibitors

scientific article published on 27 December 2016

Design, synthesis and biological evaluation of rose bengal analogues as SecA inhibitors

scientific article

Design, synthesis and preliminary activity assay of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as novel Histone deacetylases (HDACs) inhibitors

scientific article

Design, synthesis and preliminary activity evaluation of novel L-lysine derivatives as aminopeptidase N/CD13 inhibitors

scientific article

Design, synthesis and preliminary biological evaluation of 4-aminopyrazole derivatives as novel and potent JAKs inhibitors.

scientific article

Design, synthesis, and evaluation of efflux substrate-metal chelator conjugates as potential antimicrobial agents

scientific article published on 2 November 2006

Design, synthesis, and polymerase-catalyzed incorporation of click-modified boronic acid-TTP analogues

scientific article

Design, synthesis, and structure-activity relationship, molecular modeling, and NMR studies of a series of phenyl alkyl ketones as highly potent and selective phosphodiesterase-4 inhibitors

scientific article published on December 2008

Diallyl trisulfide protects against high glucose-induced cardiac apoptosis by stimulating the production of cystathionine gamma-lyase-derived hydrogen sulfide

scientific article published on 20 May 2015

Discovery and mechanistic study of a class of protein arginine methylation inhibitors.

scientific article published on August 2010

Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor ⬇️

scientific article

Discovery of novel anti-angiogenesis agents. Part 7: Multitarget inhibitors of VEGFR-2, TIE-2 and EphB4.

scientific article published on 12 October 2017

Discovery of novel anti-angiogenesis agents. Part 8: Diaryl thiourea bearing 1H-indazole-3-amine as multi-target RTKs inhibitors.

scientific article published on 6 October 2017

Discovery of the first SecA inhibitors using structure-based virtual screening

scientific article

Dual-Responsive Boronate Crosslinked Micelles for Targeted Drug Delivery

scientific article published on 18 April 2012

Effect of extended conjugation with a phenylethynyl group on the fluorescent properties of water-soluble arylboronic acids.

scientific article published on June 2007

Esterase-Sensitive Glutathione Persulfide Donor

article

Esterase-Sensitive Prodrugs with Tunable Release Rates and Direct Generation of Hydrogen Sulfide.

scientific article published on 28 January 2016

Esterase-Sensitive and pH-Controlled Carbon Monoxide Prodrugs for Treating Systemic Inflammation

scientific article published on 14 March 2019

Esterase-sensitive cyclic prodrugs of peptides: evaluation of a phenylpropionic acid promoiety in a model hexapeptide

scientific article published in January 1997

Evaluation of small molecule SecA inhibitors against methicillin-resistant Staphylococcus aureus.

scientific article

Examining the structure-activity relationship of benzopyran-based inhibitors of the hypoxia inducible factor-1 pathway

scientific article

Fibrinogen Clot Induced by Gold-Nanoparticle In Vitro

scientific article published on 01 January 2011

Fibrinogen nanofibril growth and self-assembly on Au (1,1,1) surface in the absence of thrombin.

scientific article

Fluorescein analogues inhibit SecA ATPase: the first sub-micromolar inhibitor of bacterial protein translocation

scientific article published on 22 February 2012

Fluorescent Indolylboronic Acids that are Useful Reporters for the Synthesis of Boronolectins

Fluorescent conjugate of sLe(x)-selective bisboronic acid for imaging application.

scientific article published in October 2013

Fluoride protects boronic acids in the copper(i)-mediated click reaction

scientific article published on 06 August 2009

Granular kernel trees with parallel genetic algorithms for drug activity comparisons.

scientific article published in January 2007

High-performance liquid chromatographic enantioseparation of 3,5-disubstituted hydantoins analogs and temperature-induced reversals of elution orders on a polysaccharide-based chiral stationary phase

scientific article published on 12 June 2014

Homing in on an intracellular target for delivery of loaded nanoparticles functionalized with a histone deacetylase inhibitor.

scientific article published on 7 August 2017

Homology modeling and examination of the effect of the D92E mutation on the H5N1 nonstructural protein NS1 effector domain

scientific article published on 5 October 2007

Hydrogen sulfide prodrugs-a review

scientific article

Identification of boronic acids as antagonists of bacterial quorum sensing in Vibrio harveyi

scientific article published in 2008

Identification of the first fluorescent alpha-amidoboronic acids that change fluorescent properties upon sugar binding

scientific article published on 08 February 2009

In honor of Professor Lester A. Mitscher on the occasion of his 80(th) birthday.

scientific article published in July 2012

Inhibition of MDM2 by a rhein-derived compound AQ-101 suppresses cancer development in SCID mice.

scientific article

Inhibition of Quorum Sensing inVibrio harveyiby Boronic Acids

scientific article published on 01 July 2009

Inhibitors and antagonists of bacterial quorum sensing

scientific article published on January 2009

L-Ala-γ-D-Glu-meso-diaminopimelic acid (DAP) interacts directly with leucine-rich region domain of nucleotide-binding oligomerization domain 1, increasing phosphorylation activity of receptor-interacting serine/threonine-protein kinase 2 and its int

scientific article

MALDI tissue imaging: from biomarker discovery to clinical applications.

scientific article published on 4 May 2011

Making smart drugs smarter: The importance of linker chemistry in targeted drug delivery

scientific article published on 16 August 2020

Mechanisms of Rose Bengal inhibition on SecA ATPase and ion channel activities.

scientific article published on 19 October 2014

Modeling the excitation wavelengths (lambda(ex)) of boronic acids

scientific article published on 20 March 2008

Mutual leveraging of proximity effects and click chemistry in chemical biology

scientific article published in 2022

New Boronic Acid Fluorescent Reporter Compounds. 2. A Naphthalene-Based On−Off Sensor Functional at Physiological pH†

scientific article published on 01 November 2003

New strategies in achieving antiangiogenic effect: Multiplex inhibitors suppressing compensatory activations of RTKs.

scientific article

Nitro reduction-based fluorescent probes for carbon monoxide require reactivity involving a ruthenium carbonyl moiety

scientific article published on 01 February 2020

Novel 3-phenylpropane-1,2-diamine derivates as inhibitors of aminopeptidase N (APN).

scientific article

Novel AI-2 quorum sensing inhibitors in Vibrio harveyi identified through structure-based virtual screening

scientific article

Novel Hydrogen Sulfide (H2S)-Releasing BW-HS-101 and Its Non-H2S Releasing Derivative in Modulation of Microscopic and Molecular Parameters of Gastric Mucosal Barrier ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Novel Rhein Analogues as Potential Anticancer Agents ⬇️

scientific article published on September 26, 2011

Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry

scientific article published on 22 April 2018

Organic CO Prodrugs Activated by Endogenous ROS.

scientific article published on 7 November 2017

Organic CO Prodrugs: Structure-CO-Release Rate Relationship Studies

scientific article published on 04 July 2017

Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage

scientific article

Probing the general time scale question of boronic acid binding with sugars in aqueous solution at physiological pH.

scientific article

Prodrug Strategies Based on Intramolecular Cyclization Reactions ⬇️

scientific article published on July 1, 1997

Progress in boronic acid-based fluorescent glucose sensors.

scientific article

Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi.

scientific article published on 30 January 2008

Rapid and specific post-synthesis modification of DNA through a biocompatible condensation of 1,2-aminothiols with 2-cyanobenzothiazole.

scientific article published on 28 February 2013

Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore

scientific article published on May 2008

Regulating the fluorescence intensity of an anthracene boronic acid system: a B-N bond or a hydrolysis mechanism?

scientific article published in December 2004

SecA inhibitors as potential antimicrobial agents: differential actions on SecA-only and SecA-SecYEG protein-conducting channels

scientific article published on 01 August 2018

SecA inhibitors: next generation antimicrobials

SecA: a potential antimicrobial target.

scientific article published on June 2015

SecAAA trimer is fully functional as SecAA dimer in the membrane: existence of higher oligomers?

scientific article

Selecting aptamers for a glycoprotein through the incorporation of the boronic acid moiety

scientific article

Selective elimination of perennial ryegrass by activation of a pro-herbicide through engineering E. coli argE gene

article

Small molecule inhibitors of histone acetyltransferase Tip60

scientific article

Stereoselective Synthesis of 1-Methyl-3′,4′,5′,6′-tetrahydrospiro[indoline-3,2′-pyran]-2-one Derivatives via Prins Cyclization

scientific article published on 12 May 2015

Strategies to target the Hedgehog signaling pathway for cancer therapy.

scientific article published on 5 January 2018

Strategies toward Organic Carbon Monoxide Prodrugs

article

Structure of the product from a novel cyclization reaction involving a C(6)-substituted uridine analog

scientific article published on 01 September 1993

Structure-Based Discovery and Experimental Verification of Novel AI-2 Quorum Sensing Inhibitors againstVibrio harveyi

scholarly article by Minyong Li et al published 18 August 2008 in ChemMedChem

Structure-Based Virtual Screening and Electrophysiological Evaluation of New Chemotypes of Kv1.5 Channel Blockers

Substituted coumarins as esterase-sensitive prodrug moieties with improved release rates

scientific article published in July 1999

Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors

scientific article

Sulfur dioxide prodrugs: triggered release of SO2via a click reaction.

scientific article published on 10 January 2017

Synthesis and Evaluation of Dual Wavelength Fluorescent Benzo[b]thiophene Boronic Acid Derivatives for Sugar Sensing

article by Senol Akay et al published October 2007 in Chemical Biology and Drug Design

Synthesis and carbohydrate binding studies of fluorescent alpha-amidoboronic acids and the corresponding bisboronic acids

scientific article

Synthesis and evaluation of new antagonists of bacterial quorum sensing in Vibrio harveyi.

scientific article published in September 2009

Synthesis, antimalarial activity and cytotoxic potential of new monocarbonyl analogues of curcumin ⬇️

scientific article published on November 10, 2012

Synthesis, evaluation, and computational studies of naphthalimide-based long-wavelength fluorescent boronic Acid reporters

scientific article published in January 2008

The chemistry of escapin: identification and quantification of the components in the complex mixture generated by an L-amino acid oxidase in the defensive secretion of the sea snail Aplysia californica

scientific article

The design of boronic acid spectroscopic reporter compounds by taking advantage of the pK(a)-lowering effect of diol binding: nitrophenol-based color reporters for diols

scientific article published in March 2004

The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides.

scientific article published in April 1999

The effect of different electrostatic potentials on docking accuracy: A case study using DOCK5.4

scientific article published in 2008

The effect of substitution patterns on the release rates of opioid peptides DADLE and [Leu(5)]-enkephalin from coumarin prodrug moieties

scientific article

The first low microM SecA inhibitors

scientific article

The mechanisms of boronate ester formation and fluorescent turn-on in ortho-aminomethylphenylboronic acids

scientific article published on 23 August 2019

The past 20 years of Medicinal Research Reviews

scientific article published on 09 December 2019

Thiol reactive probes and chemosensors.

scientific article

Toward Carbon Monoxide-Based Therapeutics: Critical Drug Delivery and Developability Issues

scientific article published on 6 January 2016

Toward Direct Protein S-Persulfidation: A Prodrug Approach That Directly Delivers Hydrogen Persulfide

scientific article

Toward Hydrogen Sulfide Based Therapeutics: Critical Drug Delivery and Developability Issues.

scientific article published on 27 February 2017

Toward carbon monoxide based therapeutics: carbon monoxide in a pill.

scientific article

Using Chemical Probes to Assess the Feasibility of Targeting SecA for Developing Antimicrobial Agents against Gram-Negative Bacteria.

scientific article published on 18 October 2016

Vitamin C inactivates the proteasome inhibitor PS-341 in human cancer cells

scientific article published on January 2006

Water-soluble fluorescent boronic acid compounds for saccharide sensing: substituent effects on their fluorescence properties

scientific article

pH-Sensitive metal-free carbon monoxide prodrugs with tunable and predictable release rates

scientific article published on 01 August 2017

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