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List of works by Saulius Klimasauskas

2-Aminopurine as a fluorescent probe for DNA base flipping by methyltransferases ⬇️

scientific article published on February 15, 1998

5-Hydroxymethylcytosine--the elusive epigenetic mark in mammalian DNA.

scientific article

5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary

scientific article

A basal promoter element recognized by free RNA polymerase sigma subunit determines promoter recognition by RNA polymerase holoenzyme.

scientific article published on 22 June 2006

A directed evolution design of a GCG-specific DNA hemimethylase.

scientific article published on November 2009

A new tool for biotechnology: AdoMet-dependent methyltransferases

scientific article published on 24 January 2007

A pair of single-strand and double-strand DNA cytosine-N4 methyltransferases from Bacillus centrosporus

scientific article published on 01 April 1998

Alleviation of C⋅C Mismatches in DNA by the <i>Escherichia coli</i> Fpg Protein

scientific article published on 30 June 2021

Alw26I, Eco31I and Esp3I--type IIs methyltransferases modifying cytosine and adenine in complementary strands of the target DNA

scientific article

An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing

scientific article published on 11 April 2019

Analysis of products of DNA modification by methylases: a procedure for the determination of 5- and N4-methylcytosines in DNA.

scientific article

Animal Hen1 2'-O-methyltransferases as tools for 3'-terminal functionalization and labelling of single-stranded RNAs.

scientific article published in September 2018

Approaches for studying microRNA and small interfering RNA methylation in vitro and in vivo.

scientific article published on January 2007

Archaeal fibrillarin-Nop5 heterodimer 2'-O-methylates RNA independently of the C/D guide RNP particle.

scientific article published on 2 June 2017

Biosynthetic selenoproteins with genetically-encoded photocaged selenocysteines

scientific article published in May 2015

Bisulfite sequencing protocol displays both 5-methylcytosine and N4-methylcytosine

scientific article published on 01 June 1999

Characterization of restriction-modification enzymes Cfr13 I from Citrobacter freundii RFL13

scientific article published on 01 March 1985

Chemical display of thymine residues flipped out by DNA methyltransferases

scientific article published on August 1998

Circular permutation of DNA cytosine-N4 methyltransferases: in vivo coexistence in the BcnI system and in vitro probing by hybrid formation

scientific article

Cleavage of methylated CCCGGG sequences containing either N4-methylcytosine or 5-methylcytosine with MspI, HpaII, SmaI, XmaI and Cfr9I restriction endonucleases.

scientific article

Cloning and sequence analysis of the genes coding for Eco57I type IV restriction-modification enzymes ⬇️

scientific article published on November 25, 1992

Crystal structure of the HhaI DNA methyltransferase

article

Cytosine-5-methyltransferases add aldehydes to DNA.

scientific article published in June 2009

DNA Labeling Using DNA Methyltransferases.

scientific article published on January 2016

Direct decarboxylation of 5-carboxylcytosine by DNA C5-methyltransferases

scientific article published on 14 April 2014

Direct observation of cytosine flipping and covalent catalysis in a DNA methyltransferase.

scientific article

Direct transfer of extended groups from synthetic cofactors by DNA methyltransferases

scientific article published on 27 November 2005

Disruption of the target G-C base-pair by the HhaI methyltransferase

scientific article published on 01 May 1995

Distribution and regulatory roles of oxidized 5-methylcytosines in DNA and RNA of the basidiomycete fungi <i>Laccaria bicolor</i> and <i>Coprinopsis cinerea</i>

scientific article published on 02 March 2022

Dynamic modes of the flipped-out cytosine during HhaI methyltransferase-DNA interactions in solution.

scientific article published on January 1998

Editorial overview: Current advances in analytical biotechnology: from single molecules to whole organisms

scientific article published on 07 January 2019

Engineering the DNA cytosine-5 methyltransferase reaction for sequence-specific labeling of DNA

scientific article

Enhanced chemical stability of adomet analogues for improved methyltransferase-directed labeling of DNA.

scientific article published on 10 April 2013

Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes

scientific article

Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins

scientific article published in June 2018

Functional mapping of the plant small RNA methyltransferase: HEN1 physically interacts with HYL1 and DICER-LIKE 1 proteins.

scientific article published on 12 February 2015

Functional roles of the conserved threonine 250 in the target recognition domain of HhaI DNA methyltransferase

scientific article

HhaI DNA methyltransferase uses the protruding Gln237 for active flipping of its target cytosine.

scientific article

HhaI methyltransferase flips its target base out of the DNA helix

scientific article

Interaction of AluI, Cfr6I and PvuII restriction-modification enzymes with substrates containing either N4-methylcytosine or 5-methylcytosine

scientific article published on 01 August 1987

Kinetic and functional analysis of the small RNA methyltransferase HEN1: the catalytic domain is essential for preferential modification of duplex RNA

scientific article

Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases.

scientific article published on 04 January 2016

M.HhaI binds tightly to substrates containing mismatches at the target base

scientific article

Mechanistic insights into small RNA recognition and modification by the HEN1 methyltransferase

scientific article published on 01 July 2013

Methyltransferase‐Directed Derivatization of 5‐Hydroxymethylcytosine in DNA ⬇️

scientific article published on January 26, 2011

Modulation of RNA polymerase activity through the trigger loop folding ⬇️

scientific article published on September 1, 2010

Oligonucleotide-Addressed Covalent 3'-Terminal Derivatization of Small RNA Strands for Enrichment and Visualization.

scientific article published on 4 May 2017

Phenotyping cognitive impairment in dialysis patients: insights from experimental mouse models

scientific article

Precise genomic mapping of 5-hydroxymethylcytosine via covalent tether-directed sequencing

scientific article published on 10 April 2020

Probing a rate-limiting step by mutational perturbation of AdoMet binding in the HhaI methyltransferase

scientific article

Processive methylation of hemimethylated CpG sites by mouse Dnmt1 DNA methyltransferase

scientific article published on 27 October 2004

Purification and properties of the Eco57I restriction endonuclease and methylase--prototypes of a new class (type IV) ⬇️

scientific article published on November 25, 1992

Recognition of guanosine by dissimilar tRNA methyltransferases.

scientific article published on 30 July 2012

Repurposing enzymatic transferase reactions for targeted labeling and analysis of DNA and RNA

article

Restriction endonucleases of a new type.

scientific article

Selective chemical tracking of Dnmt1 catalytic activity in live cells

scientific article published on 01 March 2022

Selective covalent labeling of miRNA and siRNA duplexes using HEN1 methyltransferase

scientific article published on 19 September 2014

Sequence motifs characteristic of DNA[cytosine-N4]methyltransferases: similarity to adenine and cytosine-C5 DNA-methylases

scientific article

Sequence similarity among type-II restriction endonucleases, related by their recognized 6-bp target and tetranucleotide-overhang cleavage

scientific article published on 01 May 1995

Solubility engineering of the HhaI methyltransferase

scientific article published in April 2003

Synthesis and physical characterization of DNA fragments containing N4-methylcytosine and 5-methylcytosine

scientific article

Synthesis of S-Adenosyl-L-Methionine Analogs with Extended Transferable Groups for Methyltransferase-Directed Labeling of DNA and RNA.

scientific article published on March 2016

Synthesis of S-adenosyl-L-methionine analogs and their use for sequence-specific transalkylation of DNA by methyltransferases

scientific article published on 01 January 2006

Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation.

scientific article

Targeted labeling of DNA by methyltransferase-directed transfer of activated groups (mTAG)

scientific article published on 20 February 2007

Tethered Oligonucleotide-Primed Sequencing, TOP-Seq: A High-Resolution Economical Approach for DNA Epigenome Profiling

scientific article published on 13 January 2017

The DNA (cytosine-5) methyltransferases

scientific article

The sequence specificity domain of cytosine-C5 methylases

scientific article

The stereochemistry of benzo[a]pyrene-2'-deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases

scientific article published on 27 March 2007

Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI-DNA complexes

scientific article

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