List of works - Simona De Marino

4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity

scientific article published on 20 January 2012

A novel sulphated steroid with a 7-membered 5-oxalactone B-ring from an Antarctic starfish of the family Asteriidae

Anti-inflammatory and analgesic activities with gastroprotective effect of semi-purified fractions and isolation of pure compounds from Mediterranean gorgonian Eunicella singularis

scientific article published on 23 July 2015

Anti-inflammatory cyclopeptides from the marine sponge Theonella swinhoei

article published in 2012

Antimicrobial furostanol saponins from the seeds of Capsicum annuum L. var. acuminatum

scientific article published in July 2002

Antioxidant activity of phenolic and phenylethanoid glycosides from Teucrium polium L

Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands.

scientific article

Bioactive asterosaponins from the starfish Luidia quinaria and Psilaster cassiope. Isolation and structure characterization by two-dimensional NMR spectroscopy

scientific article published in April 2003

Bioactive cembrane derivatives from the Indian Ocean soft coral, Sinularia kavarattiensis

scientific article

Biomolecular proteomics discloses ATP synthase as the main target of the natural glycoside deglucoruscin

scientific article published in August 2016

Coscinolactams A and B: new nitrogen-containing sesterterpenoids from the marine sponge Coscinoderma mathewsi exerting anti-inflammatory properties

article published in 2009

Differential in gel electrophoresis (DIGE) comparative proteomic analysis of macrophages cell cultures in response to perthamide C treatment

scientific article published on 17 April 2013

Epoxide functionalization on cholane side chains in the identification of G-protein coupled bile acid receptor (GPBAR1) selective agonists

scholarly article in RSC Advances, vol. 7 no. 52, 2017

Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.

scientific article

Gracilioethers E–J, new oxygenated polyketides from the marine sponge Plakinastrella mamillaris

article

Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists

scientific article

Identification of minor secondary metabolites from the latex of Croton lechleri (Muell-Arg) and evaluation of their antioxidant activity ⬇️

scientific article published in June 2008

Imbricatolic acid from Juniperus communis L. prevents cell cycle progression in CaLu-6 cells

scientific article

Investigation of the polar steroids from an Antarctic Starfish of the family Echinasteridae: isolation of twenty seven polyhydroxysteroids and steroidal oligoglycosides, structures and biological activities

article published in 1996

Isolation of Plakinamine I: A New Steroidal Alkaloid from the Marine SpongeCorticiumsp. and Synthesis of an Analogue Model Compound

Isolation, structure elucidation, and biological activity of the steroid oligoglycosides and polyhydroxysteroids from the Antarctic starfish Acodontaster conspicuus.

scientific article published on October 1997

Jaspamides H–L, new actin-targeting depsipeptides from the sponge Jaspis splendans

Jaspamides M–P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Lauroside B, a megastigmane glycoside from Laurus nobilis (bay laurel) leaves, induces apoptosis in human melanoma cell lines by inhibiting NF-κB activation

scientific article

Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulation

scientific article

Megastigmane and phenolic components from Laurus nobilis L. leaves and their inhibitory effects on nitric oxide production.

scientific article published on December 2004

Minor steroidal alkaloids from the marine sponge Corticium sp.

scientific article published in August 2002

Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists.

scientific article

New Constituents of Sweet Capsicum annuum L. Fruits and Evaluation of Their Biological Activity

scientific article published on 01 October 2006

New Pyridinium Alkaloids from a Marine Sponge of the GenusSpongiawith a Human Phospholipase A2Inhibitor Profile

scientific article published on 01 March 2000

New antimalarial polyketide endoperoxides from the marine sponge Plakinastrella mamillaris collected at Fiji Islands

New jaspamide derivatives with antimicrofilament activity from the sponge Jaspis splendans

New sesquiterpene lactones from Laurus nobilis leaves as inhibitors of nitric oxide production

scientific article

New sesquiterpenes with intestinal relaxant effect from Celastrus paniculatus

scientific article published in July 2004

Novel Steroidal Components from the Underground Parts of Ruscus aculeatus L ⬇️

scientific article published on November 26, 2012

Oxygenated polyketides from Plakinastrella mamillaris as a new chemotype of PXR agonists.

scientific article published on 2 July 2013

Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei

Perthamides C–F, potent human antipsoriatic cyclopeptides

Pharmacological evaluation of the semi-purified fractions from the soft coral Eunicella singularis and isolation of pure compounds

scientific article

Phenolic glycosides from Cucumis melo var. inodorus seeds

Phenolic glycosides from Foeniculum vulgare fruit and evaluation of antioxidative activity

scientific article published on 10 May 2007

Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches

scientific article published in 2022

Phytochemical and Biological Studies of Nepeta asterotricha Rech. f. (Lamiaceae): Isolation of Nepetamoside.

scientific article

Phytochemical profile of Juniperus oxycedrus ssp. oxycedrus berries: A new monoterpene glucoside and evaluation of the effects on cancer cell lines

Plakilactones G and H from a marine sponge. Stereochemical determination of highly flexible systems by quantitative NMR-derived interproton distances combined with quantum mechanical calculations of (13)C chemical shifts

scientific article published on 30 December 2013

Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ.

scientific article

Potent relaxant effect of a Celastrus paniculatus extract in the rat and human ileum.

scientific article published on 11 February 2009

Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei

scientific article published on 5 November 2012

Ptilomycalin A, crambescidin 800 and related new highly cytotoxic guanidine alkaloids from the starfishes Fromia monilis and Celerina heffernani

article published in 1995

Scalarane sesterterpenes from Thorectidae sponges as inhibitors of TDP-43 nuclear factor

scientific article

Solomonamides A and B, new anti-inflammatory peptides from Theonella swinhoei.

scientific article published on 22 February 2011

Solomonsterols A and B from Theonella swinhoei. The first example of C-24 and C-23 sulfated sterols from a marine source endowed with a PXR agonistic activity

scientific article published on 9 December 2010

Starfish Saponins. 55.1Isolation, Structure Elucidation, and Biological Activity of the Steroid Oligoglycosides from an Antarctic Starfish of the FamilyAsteriidae†

scientific article published on 01 November 1998

Swinholide J, a potent cytotoxin from the marine sponge Theonella swinhoei

scientific article published on 22 June 2011

Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases

scientific article published on 30 March 2017

Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors.

scientific article

Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei

scientific article published on 16 May 2011

Triterpenoid profile and bioactivity study of Oenothera maritima

Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116

scientific article published on 05 June 2019

List of works by Simona De Marino

4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity

A novel sulphated steroid with a 7-membered 5-oxalactone B-ring from an Antarctic starfish of the family Asteriidae

Anti-inflammatory and analgesic activities with gastroprotective effect of semi-purified fractions and isolation of pure compounds from Mediterranean gorgonian Eunicella singularis

Anti-inflammatory cyclopeptides from the marine sponge Theonella swinhoei

Antimicrobial furostanol saponins from the seeds of Capsicum annuum L. var. acuminatum

Antioxidant activity of phenolic and phenylethanoid glycosides from Teucrium polium L

Binding mechanism of the farnesoid X receptor marine antagonist suvanine reveals a strategy to forestall drug modulation on nuclear receptors. Design, synthesis, and biological evaluation of novel ligands.

Bioactive asterosaponins from the starfish Luidia quinaria and Psilaster cassiope. Isolation and structure characterization by two-dimensional NMR spectroscopy

Bioactive cembrane derivatives from the Indian Ocean soft coral, Sinularia kavarattiensis

Biomolecular proteomics discloses ATP synthase as the main target of the natural glycoside deglucoruscin

Coscinolactams A and B: new nitrogen-containing sesterterpenoids from the marine sponge Coscinoderma mathewsi exerting anti-inflammatory properties

Differential in gel electrophoresis (DIGE) comparative proteomic analysis of macrophages cell cultures in response to perthamide C treatment

Epoxide functionalization on cholane side chains in the identification of G-protein coupled bile acid receptor (GPBAR1) selective agonists

Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands.

Gracilioethers E–J, new oxygenated polyketides from the marine sponge Plakinastrella mamillaris

Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists

Identification of minor secondary metabolites from the latex of Croton lechleri (Muell-Arg) and evaluation of their antioxidant activity ⬇️

Imbricatolic acid from Juniperus communis L. prevents cell cycle progression in CaLu-6 cells

Investigation of the polar steroids from an Antarctic Starfish of the family Echinasteridae: isolation of twenty seven polyhydroxysteroids and steroidal oligoglycosides, structures and biological activities

Isolation of Plakinamine I: A New Steroidal Alkaloid from the Marine SpongeCorticiumsp. and Synthesis of an Analogue Model Compound

Isolation, structure elucidation, and biological activity of the steroid oligoglycosides and polyhydroxysteroids from the Antarctic starfish Acodontaster conspicuus.

Jaspamides H–L, new actin-targeting depsipeptides from the sponge Jaspis splendans

Jaspamides M–P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

Lauroside B, a megastigmane glycoside from Laurus nobilis (bay laurel) leaves, induces apoptosis in human melanoma cell lines by inhibiting NF-κB activation

Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulation

Megastigmane and phenolic components from Laurus nobilis L. leaves and their inhibitory effects on nitric oxide production.

Minor steroidal alkaloids from the marine sponge Corticium sp.

Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists.

New Constituents of Sweet Capsicum annuum L. Fruits and Evaluation of Their Biological Activity

New Pyridinium Alkaloids from a Marine Sponge of the GenusSpongiawith a Human Phospholipase A2Inhibitor Profile

New antimalarial polyketide endoperoxides from the marine sponge Plakinastrella mamillaris collected at Fiji Islands

New jaspamide derivatives with antimicrofilament activity from the sponge Jaspis splendans

New sesquiterpene lactones from Laurus nobilis leaves as inhibitors of nitric oxide production

New sesquiterpenes with intestinal relaxant effect from Celastrus paniculatus

Novel Steroidal Components from the Underground Parts of Ruscus aculeatus L ⬇️

Oxygenated polyketides from Plakinastrella mamillaris as a new chemotype of PXR agonists.

Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei

Perthamides C–F, potent human antipsoriatic cyclopeptides

Pharmacological evaluation of the semi-purified fractions from the soft coral Eunicella singularis and isolation of pure compounds

Phenolic glycosides from Cucumis melo var. inodorus seeds

Phenolic glycosides from Foeniculum vulgare fruit and evaluation of antioxidative activity

Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and Biological Profile Using Computational Approaches

Phytochemical and Biological Studies of Nepeta asterotricha Rech. f. (Lamiaceae): Isolation of Nepetamoside.

Phytochemical profile of Juniperus oxycedrus ssp. oxycedrus berries: A new monoterpene glucoside and evaluation of the effects on cancer cell lines

Plakilactones G and H from a marine sponge. Stereochemical determination of highly flexible systems by quantitative NMR-derived interproton distances combined with quantum mechanical calculations of (13)C chemical shifts

Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ.

Potent relaxant effect of a Celastrus paniculatus extract in the rat and human ileum.

Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei

Ptilomycalin A, crambescidin 800 and related new highly cytotoxic guanidine alkaloids from the starfishes Fromia monilis and Celerina heffernani

Scalarane sesterterpenes from Thorectidae sponges as inhibitors of TDP-43 nuclear factor

Solomonamides A and B, new anti-inflammatory peptides from Theonella swinhoei.

Solomonsterols A and B from Theonella swinhoei. The first example of C-24 and C-23 sulfated sterols from a marine source endowed with a PXR agonistic activity

Starfish Saponins. 55.1Isolation, Structure Elucidation, and Biological Activity of the Steroid Oligoglycosides from an Antarctic Starfish of the FamilyAsteriidae†

Swinholide J, a potent cytotoxin from the marine sponge Theonella swinhoei

Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases

Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors.

Towards new ligands of nuclear receptors. Discovery of malaitasterol A, an unique bis-secosterol from marine sponge Theonella swinhoei

Triterpenoid profile and bioactivity study of Oenothera maritima

Wound healing activity and phytochemical screening of purified fractions of Sempervivum tectorum L. leaves on HCT 116