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List of works by Ezio Bonifacio

A divergent population of autoantigen-responsive CD4+ T cells in infants prior to β cell autoimmunity

scientific article published on February 2017

A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes.

scientific article published on 8 March 2018

A report on the International Transglutaminase Autoantibody Workshop for Celiac Disease

scientific article

A simplified method to assess affinity of insulin autoantibodies

scientific article published on 01 December 2010

A strategy for combining minor genetic susceptibility genes to improve prediction of disease in type 1 diabetes

article

A strategy to find gene combinations that identify children who progress rapidly to type 1 diabetes after islet autoantibody seroconversion

scientific article published on 19 November 2013

A type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes.

scientific article

Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children

scientific article

Adoptive transfer of allogeneic regulatory T cells into patients with chronic graft-versus-host disease

scientific article published on 06 January 2015

Advances in the prediction and natural history of type 1 diabetes

scientific article published on September 2010

Age- and islet autoimmunity-associated differences in amino acid and lipid metabolites in children at risk for type 1 diabetes

scientific article published on November 2011

Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes

scientific article published on 01 July 2012

An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes ⬇️

scientific article

An update on preventive and regenerative therapies in diabetes mellitus

scientific article published on 25 December 2008

Anti-CCL3 autoantibodies are not markers of type 1 diabetes when measured by a commercial ELISA method

scientific article published on 03 December 2010

Assessment of the T cell receptor repertoire in long-term platelet donors by next generation sequencing.

scientific article published on 8 March 2017

Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission

scientific article published on 22 March 2007

Association of interferon-gamma and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes

scientific article published on 01 September 2006

Autoantibodies to IA-2beta improve diabetes risk assessment in high-risk relatives.

scientific article published on 9 January 2008

Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk

scientific article published on 10 July 2009

Azide and Tween-20 reduce binding to autoantibody epitopes of islet antigen-2; implications for assay performance and reproducibility

scientific article

BMI at age 8 years is influenced by the type 2 diabetes susceptibility genes HHEX-IDE and CDKAL1

scientific article

Beta cell chromogranin B is partially segregated in distinct granules and can be released separately from insulin in response to stimulation.

scientific article

Beta cell function during rapamycin monotherapy in long-term type 1 diabetes.

scientific article published on 3 November 2010

Beta-cell autoimmunity

scientific article published on January 2012

Birth and coming of age of islet autoantibodies

scientific article published on 12 September 2019

Breastfeeding habits in families with Type 1 diabetes

scientific article published on 2 April 2007

C-reactive protein concentration is not related to islet autoimmunity status in offspring of parents with type 1 diabetes

scientific article published on 01 May 2005

CXCR1/2 inhibition enhances pancreatic islet survival after transplantation

scientific article

Characterization of antibody responses to endogenous and exogenous antigen in the nonobese diabetic mouse

scientific article published in February 2003

Co-graft of allogeneic immune regulatory neural stem cells (NPC) and pancreatic islets mediates tolerance, while inducing NPC-derived tumors in mice

scientific article

Combined testing of antibody titer and affinity improves insulin autoantibody measurement: Diabetes Antibody Standardization Program

scientific article published on 23 October 2006

Compromised gut microbiota networks in children with anti-islet cell autoimmunity

scientific article published on 7 March 2014

Concentration and activity of the soluble form of the interleukin-7 receptor α in type 1 diabetes identifies an interplay between hyperglycemia and immune function

scientific article published on March 2013

Delayed exposure to wheat and barley proteins reduces diabetes incidence in non-obese diabetic mice

scientific article

Development of autoimmunity to transglutaminase C in children of patients with type 1 diabetes: relationship to islet autoantibodies and infant feeding

scientific article published on 14 December 2006

Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2.

scientific article published on 29 March 2008

Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies

scientific article published on 25 September 2010

Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis.

scientific article published on 15 December 2016

Differentiation, expansion, and homeostasis of autoreactive T cells in type 1 diabetes mellitus

scientific article published on April 2009

Disengaging the IL-2 receptor with daclizumab enhances IL-7-mediated proliferation of CD4(+) and CD8(+) T cells

scientific article published on 25 September 2009

Endocrine autoimmunity in families with type 1 diabetes: frequent appearance of thyroid autoimmunity during late childhood and adolescence

scientific article published on 19 November 2008

Erratum to: Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes

article

Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes

scientific article

Exposure to environmental factors in drinking water: risk of islet autoimmunity and type 1 diabetes--the BABYDIAB study

scientific article

Feature ranking of type 1 diabetes susceptibility genes improves prediction of type 1 diabetes

scientific article published on 4 September 2014

Fetal growth is increased by maternal type 1 diabetes and HLA DR4-related gene interactions

scientific article published on 20 February 2007

Fine mapping of diabetes-associated IA-2 specific autoantibodies

scientific article (publication date: December 2003)

GAD autoantibodies and epitope reactivities persist after diagnosis in latent autoimmune diabetes in adults but do not predict disease progression: UKPDS 77

scientific article published on 27 July 2007

GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for type 1 diabetes

scientific article published on 26 February 2007

GAD autoantibody affinity in adult patients with latent autoimmune diabetes, the study participants of a GAD65 vaccination trial

scientific article published on 5 March 2014

GM-CSF producing autoreactive CD4+ T cells in type 1 diabetes

scientific article published on 8 December 2017

Generation of high-avidity, WT1-reactive CD8+ cytotoxic T cell clones with anti-leukemic activity by streptamer technology

scientific article published on 16 November 2016

Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases

scientific article

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.

scientific article published on 3 April 2018

Ghrelin-producing epsilon cells in the developing and adult human pancreas.

scientific article published on 19 December 2008

HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes

scientific article published on 21 July 2009

Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia

scientific article

Heparin-induced Extracorporal LDL precipitation (H.E.L.P) in diabetic foot syndrome - preventive and regenerative potential?

scientific article published on 01 July 2008

Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study

scientific article published on 08 July 2020

High levels of donor CCL2/MCP-1 predict graft-related complications and poor graft survival after kidney-pancreas transplantation

scientific article

Humoral autoimmune responses to glutamic acid decarboxylase have similar target epitopes and subclass that show titer-dependent disease association

scientific article published on 01 October 2005

IA-2 antibody prevalence and risk assessment of early insulin requirement in subjects presenting with type 2 diabetes (UKPDS 71).

scientific article

IA-2 autoantibody affinity in children at risk for type 1 diabetes.

scientific article

IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity.

scientific article published on 16 May 2003

IGRP and insulin vaccination induce CD8+ T cell-mediated autoimmune diabetes in the RIP-CD80GP mouse

scientific article

IL-7 abrogates suppressive activity of human CD4+CD25+FOXP3+ regulatory T cells and allows expansion of alloreactive and autoreactive T cells

scientific article published on 5 November 2012

Identification of insulin autoantibodies of IgA isotype that preferentially target non-human insulin

scientific article published on 23 May 2007

Immune responses to glutamic acid decarboxylase and insulin in patients with gestational diabetes

scientific article published on 01 February 2004

Immunotherapy in type 1 diabetes: a shorter but more winding road?

scientific article published on September 2012

Impaired insulin turnover in islets from type 2 diabetic patients

scientific article published on January 2010

In insulin-autoantibody-positive children from the general population, antibody affinity identifies those at high and low risk

scientific article published on 12 July 2005

Incomplete immune response to coxsackie B viruses associates with early autoimmunity against insulin

scientific article published on 8 September 2016

Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells

scientific article published in June 2006

Influence of early nutritional components on the development of murine autoimmune diabetes

scientific article

Insulin autoantibodies with high affinity to the bovine milk protein alpha casein

scientific article published on 01 March 2011

Interleukin-7 and type 1 diabetes

scientific article published on January 2014

Is islet autoimmunity related to insulin sensitivity or body weight in children of parents with type 1 diabetes?

scientific article published on 30 July 2009

Islet isolation for allotransplantation: variables associated with successful islet yield and graft function

scientific article published on 14 April 2005

Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells

scientific article published in May 2008

Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors

scientific article published in February 2018

Mass spectrometry-based identification of a naturally presented receptor tyrosine kinase-like orphan receptor 1-derived epitope recognized by CD8+ cytotoxic T cells

scientific article published on 24 August 2017

Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4+ T Cells in Offspring

scientific article published on 02 January 2020

Maternal immunity to insulin does not affect diabetes risk in progeny of non obese diabetic mice

scientific article published in April 2004

Maternal type 1 diabetes reduces the risk of islet autoantibodies: relationships with birthweight and maternal HbA(1c).

scientific article published on 8 May 2008

Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes

scientific article published on August 2004

Measuring T cell receptor and T cell gene expression diversity in antigen-responsive human CD4+ T cells

scientific article published on 13 November 2013

Mesenchymal Cells Appearing in Pancreatic Tissue Culture are Bone Marrow-Derived Stem Cells With the Capacity to Improve Transplanted Islet Function

article

Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function

scientific article published on January 2010

Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model.

scientific article published on 20 November 2013

Monoclonal antibody 76F distinguishes IA-2 from IA-2beta and overlaps an autoantibody epitope.

scientific article published on 24 February 2006

Neonatal and infant beta cell hormone concentrations in relation to type 1 diabetes risk

scientific article published on 19 February 2014

Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes

scientific article

No effect of the 1alpha,25-dihydroxyvitamin D3 on beta-cell residual function and insulin requirement in adults with new-onset type 1 diabetes ⬇️

scientific article

No evidence of diabetes-specific CD38 (ADP ribosil cyclase/cyclic ADP-ribose hydrolase) autoantibodies by liquid-phase immunoprecipitation

article

Novel minor HLA DR associated antigens in type 1 diabetes

scientific article published on 07 July 2018

Oral insulin immunotherapy in children at risk for type 1 diabetes in a randomised controlled trial

scientific article published on 30 January 2021

Pretransplantation GAD-autoantibody status to guide prophylactic antibody induction therapy in simultaneous pancreas and kidney transplantation

scientific article published in October 2013

Primary dietary intervention study to reduce the risk of islet autoimmunity in children at increased risk for type 1 diabetes: the BABYDIET study

scientific article

Prospective evaluation of risk factors for the development of islet autoimmunity and type 1 diabetes during puberty - TEENDIAB: study design ⬇️

scientific article published on March 29, 2011

Radiobinding assay for detecting autoantibodies to single epitopes

scientific article published in May 2008

Rapamycin Induces a Caspase-Independent Cell Death in Human Monocytes

scientific article published on 01 June 2006

Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells

scientific article published on 16 June 2008

Reduced IL-4 associated antibody responses to vaccine in early pre-diabetes

scientific article published on 17 April 2002

Relevance of hyperglycemia on the timing of functional loss of allogeneic islet transplants: implication for mouse model

scientific article published in January 2007

Risk of pediatric celiac disease according to HLA haplotype and country

scientific article

Role of CCL2/MCP-1 in islet transplantation

scientific article published on 11 June 2010

Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children

scientific article published on June 2013

Six months of gluten-free diet do not influence autoantibody titers, but improve insulin secretion in subjects at high risk for type 1 diabetes

scientific article

Soluble interleukin-2 receptor alpha in preclinical type 1 diabetes

scientific article published on 05 September 2013

T-cell receptor-α repertoire of CD8+ T cells following allogeneic stem cell transplantation using next-generation sequencing

scholarly article by Cornelia S Link-Rachner et al published March 2019 in Haematologica

The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results

scientific article published on 24 September 2008

The effect of gestation and fetal mismatching on the development of autoimmune diabetes in non-obese diabetic mice

scientific article published in June 2012

The use of biomaterials in islet transplantation

scientific article

Thymus Growth and Fetal Immune Responses in Diabetic Pregnancies

scientific article published on 14 November 2017

Timing of gluten introduction and islet autoimmunity in young children: updated results from the BABYDIET study

scientific article published on 01 September 2014

Tissue factor and CCL2/monocyte chemoattractant protein-1 released by human islets affect islet engraftment in type 1 diabetic recipients

scientific article published in November 2004

Tonic Signaling and Its Effects on Lymphopoiesis of CAR-Armed Hematopoietic Stem and Progenitor Cells

scientific article published on 06 February 2019

Transplant estimated function: a simple index to evaluate beta-cell secretion after islet transplantation

scientific article published on 31 October 2007

Transplantation of human islets without immunosuppression

scientific article published on 28 October 2013

Type 1 diabetes risk assessment: improvement by follow-up measurements in young islet autoantibody-positive relatives

scientific article published on 26 September 2006

Why is the presence of autoantibodies against GAD associated with a relatively slow progression to clinical diabetes?

scientific article published on 26 May 2020

Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes: Non Insulin Requiring Autoimmune Diabetes (NIRAD) 4.

scientific article

[Breastfeeding in women with gestational diabetes]

scientific article published on 01 February 2008

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