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List of works by Ulrike Koehl

10-Parameter Flow Cytometry as a New Tool to Improve Diagnosis and MRD Follow-Up of Acute Leukemias

scientific article published on 04 November 2009

111In-labeled CD34+ hematopoietic progenitor cells in a rat myocardial infarction model.

scientific article published on March 2004

A novel four-colour flow cytometric assay to determine natural killer cell or T-cell-mediated cellular cytotoxicity against leukaemic cells in peripheral or bone marrow specimens containing greater than 20% of normal cells

scientific article

Activation of Epac stimulates integrin-dependent homing of progenitor cells

scientific article published on 21 November 2007

Adoptive antifungal T cell immunotherapy – into the clinic?

scientific article published on 30 June 2010

Advanced flowcytometric analysis of regulatory T cells: CD127 downregulation early post stem cell transplantation and altered Treg/CD3(+)CD4(+)-ratio in severe GvHD or relapse

scientific article published on 3 August 2011

Age-matched dendritic cell subpopulations reference values in childhood.

scientific article published in March 2013

Age-matched lymphocyte subpopulation reference values in childhood and adolescence: application of exponential regression analysis

scientific article published on 12 February 2008

An improved bicistronic CD20/tCD34 vector for efficient purification and in vivo depletion of gene-modified T cells for adoptive immunotherapy

scientific article

Autologous transplantation of CD133 selected hematopoietic progenitor cells in a pediatric patient with relapsed leukemia

scientific article published on 01 June 2002

Bovine seminal ribonuclease exerts selective cytotoxicity toward neuroblastoma cells both sensitive and resistant to chemotherapeutic drugs

scientific article

CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties

scientific article

CD34(+)-selected stem cell boost for delayed or insufficient engraftment after allogeneic stem cell transplantation

scientific article published in January 2006

Challenges and Prospects of Adoptive Immunotherapy in Prevention and Treatment of Opportunistic Mycoses in Hematologic Transplant Recipients ⬇️

scientific article published on November 1, 2010

Changes in host defence induced by malignancies and antineoplastic treatment: implication for immunotherapeutic strategies

scientific article published on March 2008

Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol

scientific article published on 17 May 2013

Clinical-grade purification of natural killer cells in haploidentical hematopoietic stem cell transplantation

scientific article published on 01 February 2009

Clinical-scale generation of human anti-Aspergillus T cells for adoptive immunotherapy.

scientific article published on September 2008

Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia

article

Consensus of German transplant centers on hematopoietic stem cell transplantation in Fanconi anemia.

scientific article published on 18 May 2015

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

scientific article

Correction: Sequential Anti-Cytomegalovirus Response Monitoring May Allow Prediction of Cytomegalovirus Reactivation after Allogeneic Stem Cell Transplantation.

scientific article published on 18 April 2013

Cultivated anti-Aspergillus T(H)1 cells

scientific article published on 10 June 2008

Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids

scientific article

Detection of neuroblastoma cells during clinical follow up: advanced flow cytometry and rt-PCR for tyrosine hydroxylase using both conventional and real-time PCR ⬇️

scientific article published on November 17, 2011

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1.

scientific article

Effective treatment of leukemic cell lines with wt1 siRNA.

scientific article published on 9 August 2007

Enrichment of cell subpopulations applying automated MACS technique: purity, recovery and applicability for PCR-based chimerism analysis.

scientific article published on 4 May 2009

Enumeration of functionally active anti-Aspergillus T-cells in human peripheral blood

scientific article published on 20 March 2008

Ex vivo pretreatment of bone marrow mononuclear cells with endothelial NO synthase enhancer AVE9488 enhances their functional activity for cell therapy

scientific article published on 18 September 2006

Experiences with haploidentical stem cell transplantation in children with acute lymphoblastic leukemia

scientific article published on 01 April 2005

Fatal neonatal-onset mitochondrial respiratory chain disease with T cell immunodeficiency.

scientific article

Generation and characterization of anti-Candida T cells as potential immunotherapy in patients with Candida infection after allogeneic hematopoietic stem-cell transplant

scientific article published on 18 June 2007

Generation of highly purified and functionally active human TH1 cells against Aspergillus fumigatus

scientific article published on 01 December 2005

Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

scientific article

Hourly monitoring of circulating CD34+ cells to optimize timing of autologous apheresis in pediatric patients

scientific article published on 01 September 2005

Human natural killer cells exhibit direct activity against Aspergillus fumigatus hyphae, but not against resting conidia.

scientific article published on 14 December 2010

IL-2 activated NK cell immunotherapy of three children after haploidentical stem cell transplantation

scientific article published in November 2004

IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study

scientific article

IL-2-activated haploidentical NK cells restore NKG2D-mediated NK-cell cytotoxicity in neuroblastoma patients by scavenging of plasma MICA.

scientific article

IL-2−driven Regulation of NK Cell Receptors With Regard to the Distribution of CD16+ and CD16− Subpopulations and In Vivo Influence After Haploidentical NK Cell Infusion

scientific article published on 01 February 2010

ISHAGE-based single-platform flowcytometric analysis for measurement of absolute viable T cells in fresh or cryopreserved products: CD34/CD133 selected or CD3/CD19 depleted stem cells, DLI and purified CD56+CD3− NK cells

scientific article published on 18 December 2007

Immune recovery in children undergoing allogeneic stem cell transplantation: absolute CD8+CD3+ count reconstitution is associated with survival

scientific article published on 01 March 2007

Immunosenescence-associated microRNAs in age and heart failure

scientific article published on 20 December 2012

Immunotherapy against invasive fungal diseases in stem cell transplant recipients

scientific article published on 31 May 2011

Immunotherapy in children: report from the Reisensburg-Symposium October 20-22, 2004 and recent advances.

scientific article published on November 2006

Impact of minimal residual disease detection prior to autologous stem cell transplantation for post-transplant outcome in high risk neuroblastoma

scientific article published on 29 February 2012

Impaired pneumococcal immunity in children after treatment for acute lymphoblastic leukaemia

scientific article published on 18 September 2009

Interleukin-2-stimulated natural killer cells are less susceptible to mycophenolate mofetil than non-activated NK cells: possible consequences for immunotherapy

scientific article published on 08 May 2014

Kinetics of cell death in T lymphocytes genetically modified with two novel suicide fusion genes

scientific article published in July 2003

Lentivirus-induced 'Smart' dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma

scientific article

Mechanisms of Tumor and Viral Immune Escape from Natural Killer Cell-Mediated Surveillance ⬇️

scientific article published on May 11, 2011

Meningitis due to multiple-resistant penicillin- and cefotaxime-intermediate Streptococcus pneumoniae in a German child after bone marrow transplantation

scientific article

Mesenchymal stromal cells for treatment of steroid-refractory GvHD: a review of the literature and two pediatric cases.

scientific article

Multimer monitoring of CMV-specific T cells in research and in clinical applications.

scientific article

Multivariate analyses of immune reconstitution in children after allo-SCT: risk-estimation based on age-matched leukocyte sub-populations

scientific article published on 24 August 2009

Myeloid and plasmacytoid dendritic cells: reference ranges in the peripheral blood of healthy children

scientific article published on 24 October 2013

NK cells engineered to express a GD2 -specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin.

scientific article published on March 2012

Natural killer cells and antifungal host response.

scientific article published on 30 January 2013

Natural-killer-cell-based treatment in haematopoietic stem-cell transplantation.

scientific article published on January 2006

New insights to the MLL recombinome of acute leukemias

scientific article

No effect of antifungal compounds on functional properties of human antifungal T-helper type 1 cells.

scientific article published on 6 May 2013

Pharmacology of intracellular cytosine-arabinoside-5'-triphosphate in malignant cells of pediatric patients with initial or relapsed leukemia and in normal lymphocytes.

scientific article published on 14 December 2006

Pre-emptive immunotherapy with purified natural killer cells after haploidentical SCT: a prospective phase II study in two centers.

scientific article published on 3 September 2012

Quantification of chimerism within peripheral blood, bone marrow and purified leukocyte subsets: comparison of singleplex and multiplex PCR amplification of short tandem repeat (STR) loci

scientific article published on 01 March 2006

Quantitative analysis of chimerism after allogeneic stem cell transplantation by PCR amplification of microsatellite markers and capillary electrophoresis with fluorescence detection: the Frankfurt experience.

scientific article

Rapid immune recovery and low TRM in haploidentical stem cell transplantation in children and adolescence using CD3/CD19-depleted stem cells

scientific article published on 25 June 2011

Reactive oxygen species abrogate the anticarcinogenic effect of eicosapentaenoic acid in Atm-deficient mice

scientific article published on January 2010

Regulation of advanced therapy medicinal products in Europe and the role of academia

scientific article published on 08 October 2013

Revaccination of children after completion of standard chemotherapy for acute lymphoblastic leukaemia: a pilot study comparing different schedules

scientific article published on 20 January 2011

Sequential anti-cytomegalovirus response monitoring may allow prediction of cytomegalovirus reactivation after allogeneic stem cell transplantation

scientific article

Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors

scientific article published on 10 October 2010

Successful Combination of Sequential Gene Therapy and Rescue Allo-HSCT in Two Children with X-CGD - Importance of Timing

scientific article published on 15 May 2015

T cells for suicide gene therapy: activation, functionality and clinical relevance

scientific article published on 10 December 2007

Targeted cell entry of lentiviral vectors

scientific article published on 24 June 2008

Tecelac as antithymocyte globulin in conditioning for childhood allogeneic stem cell transplantation.

scientific article published in June 2002

Tetramer monitoring to assess risk factors for recurrent cytomegalovirus reactivation and reconstitution of antiviral immunity post allogeneic hematopoietic stem cell transplantation

scientific article published on 18 May 2011

The MLL recombinome of acute leukemias

scientific article published on 01 May 2006

The cytotoxic potential of interleukin-15-stimulated cytokine-induced killer cells against leukemia cells

scientific article published on 6 October 2011

The hedgehog inhibitor cyclopamine induces apoptosis in leukemic cells in vitro

scientific article

The novel chimeric anti-NCAM (neural cell adhesion molecule) antibody ch.MK1 displays antitumor activity in SCID mice but does not activate complement-dependent cytolysis (CDC).

scientific article

Treatment of patients with advanced cancer with the natural killer cell line NK-92.

scientific article published on October 2013

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