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List of works by Paula A Witt-Enderby

2-[(2,3-dihydro-1H-indol-1-yl)methyl]melatonin analogues: a novel class of MT2-selective melatonin receptor antagonists

scientific article published in February 2009

A novel calcium aluminate-melatonin scaffold enhances bone regeneration within a calvarial defect.

scientific article published on 30 March 2012

Biological effects of melatonin on osteoblast/osteoclast cocultures, bone, and quality of life: Implications of a role for MT2 melatonin receptors, MEK1/2, and MEK5 in melatonin-mediated osteoblastogenesis.

scientific article published on 28 December 2017

C-terminal domains within human MT1 and MT2 melatonin receptors are involved in internalization processes.

scientific article

Chronic exposure to a β2-adrenoceptor agonist increases the airway response to methacholine

scientific article published on 01 September 1993

Could the Fountain of Youth Be All in Your Bones?

scientific article published on 01 February 2013

Desensitization and internalization of the m2 muscarinic acetylcholine receptor are directed by independent mechanisms.

scientific article

Determination of the minimal melatonin exposure required to induce osteoblast differentiation from human mesenchymal stem cells and these effects on downstream signaling pathways.

scientific article published on 6 July 2010

Down-regulation of mt1 melatonin receptors in rat ovary following estrogen exposure.

scientific article published in May 2001

Drug conjugates—an emerging approach to treat breast cancer.

scientific article

Dual coupling of MT(1) and MT(2) melatonin receptors to cyclic AMP and phosphoinositide signal transduction cascades and their regulation following melatonin exposure.

scientific article

Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release.

scientific article published on 5 September 2017

Effects on bone by the light/dark cycle and chronic treatment with melatonin and/or hormone replacement therapy in intact female mice.

scientific article published on 28 May 2012

High affinity nuclear and nongenomic estradiol binding sites in the human and mouse lens.

scientific article published on 15 April 2013

Knock-down of RGS4 and beta tubulin in CHO cells expressing the human MT1 melatonin receptor prevents melatonin-induced receptor desensitization

scientific article published in October 2004

MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.

scientific article

MT1 melatonin receptor internalization underlies melatonin-induced morphologic changes in Chinese hamster ovary cells and these processes are dependent on Gi proteins, MEK 1/2 and microtubule modulation

scientific article

Melatonin and breast cancer: cellular mechanisms, clinical studies and future perspectives.

scientific article

Melatonin differentially modulates the expression and function of the hMT1 and hMT2 melatonin receptors upon prolonged withdrawal

scientific article published in March 2003

Melatonin effects on bone: potential use for the prevention and treatment for osteopenia, osteoporosis, and periodontal disease and for use in bone-grafting procedures.

scientific article published on 15 January 2014

Melatonin enhances alkaline phosphatase activity in differentiating human adult mesenchymal stem cells grown in osteogenic medium via MT2 melatonin receptors and the MEK/ERK (1/2) signaling cascade.

scientific article

Melatonin osteoporosis prevention study (MOPS): a randomized, double-blind, placebo-controlled study examining the effects of melatonin on bone health and quality of life in perimenopausal women

scientific article published on 6 January 2012

Melatonin-micronutrients Osteopenia Treatment Study (MOTS): a translational study assessing melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7) on bone density, bone marker turnover and health related quality of life in postmenopausal os

scientific article published on 26 January 2017

Modulation of melatonin receptors and G-protein function by microtubules

scientific article published in November 2006

Morinda citrifolia (Noni) Juice Augments Mammary Gland Differentiation and Reduces Mammary Tumor Growth in Mice Expressing the Unactivated c-erbB2 Transgene.

scientific article

N-Acetyl-5-arylalkoxytryptamine analogs: probing the melatonin receptors for MT(1) -selectivity.

scientific article published on 2 September 2011

Novel Melatonin, Estrogen, and Progesterone Hormone Therapy Demonstrates Anti-Cancer Actions in MCF-7 and MDA-MB-231 Breast Cancer Cells

scientific article published on 24 June 2020

Oxyprenylated Phenylpropanoids Bind to MT1 Melatonin Receptors and Inhibit Breast Cancer Cell Proliferation and Migration.

scientific article

Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs

scientific article published on 20 June 2019

Physiological Exposure to Melatonin Supersensitizes the Cyclic Adenosine 3′,5′-Monophosphate-Dependent Signal Transduction Cascade in Chinese Hamster Ovary Cells Expressing the Human mt1 Melatonin Receptor* ⬇️

scientific article published on July 1, 1998

Platelet-rich preparations to improve healing. Part I: workable options for every size practice.

scientific article

Platelet-rich preparations to improve healing. Part II: platelet activation and enrichment, leukocyte inclusion, and other selection criteria.

scientific article

Synthesis and pharmacological evaluation of 1,2,3,4-tetrahydropyrazino[1,2-a]indole and 2-[(phenylmethylamino)methyl]-1H-indole analogues as novel melatoninergic ligands.

scientific article published on 5 May 2009

Synthesis and pharmacological evaluation of pentacyclic 6a,7-dihydrodiindole and 2,3-dihydrodiindole derivatives as novel melatoninergic ligands

scientific article published on 10 July 2008

Synthesis, NMR conformational analysis and pharmacological evaluation of 7,7a,13,14-tetrahydro-6H-cyclobuta[b]pyrimido[1,2-a:3,4-a']diindole analogues as melatonin receptor ligands.

scientific article published on 25 May 2007

The actions of a charged melatonin receptor ligand, TMEPI, and an irreversible MT2 receptor agonist, BMNEP, on mouse hippocampal evoked potentials in vitro

scientific article published in November 2004

The effect of estradiol, progesterone, and melatonin on estrous cycling and ovarian aromatase expression in intact female mice

scientific article

Therapeutic treatments potentially mediated by melatonin receptors: potential clinical uses in the prevention of osteoporosis, cancer and as an adjuvant therapy

scientific article

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