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List of works by Vasilis Pachnis

A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity

scientific article

Analysis of neural crest-derived clones reveals novel aspects of facial development

scientific article

Ascl1 Is Required for the Development of Specific Neuronal Subtypes in the Enteric Nervous System.

scientific article published in April 2016

Cdt1 and geminin are down-regulated upon cell cycle exit and are over-expressed in cancer-derived cell lines

scientific article published on August 2004

Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts.

scientific article published in January 1996

Contribution of Neural Crest-Derived Cells in the Embryonic and Adult Thymus

scientific article published on 01 March 2008

Corrigendum: Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep

scientific article published on 27 September 2017

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

scientific article (publication date: 27 January 1994)

Development of the enteric nervous system: bringing together cells, signals and genes

scientific article published on February 2009

Development of the intrinsic and extrinsic innervation of the gut.

scientific article published on 22 April 2016

Differential RET signaling pathways drive development of the enteric lymphoid and nervous systems

scientific article

Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis

scientific article

Differential geminin requirement for proliferation of thymocytes and mature T cells

scientific article

Emerging roles of gut microbiota and the immune system in the development of the enteric nervous system

scientific article

Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies

scientific article published on June 2007

Enteric nervous system development: Recent progress and future challenges.

scientific article published on 23 September 2009

Enteric nervous system progenitors are coordinately controlled by the G protein-coupled receptor EDNRB and the receptor tyrosine kinase RET.

scientific article

Expression of the c-ret proto-oncogene during mouse embryogenesis

scientific article published on 01 December 1993

Expression of theRET proto-oncogene in human Embryos

scientific article published on 28 December 1998

Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes

scholarly article

Fgf-8 determines rostral-caudal polarity in the first branchial arch.

scientific article published in January 1999

Flanking regulatory sequences of the locus encoding the murine GDNF receptor, c‐ret, directs lac Z (β‐galactosidase) expression in developing somatosensory system ⬇️

scientific article published on November 1, 2001

Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability

scientific article

Galanin regulates prolactin release and lactotroph proliferation

scientific article published on October 1998

Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis

scientific article

Geminin regulates cortical progenitor proliferation and differentiation

scientific article published in August 2011

Getting to the guts of enteric nervous system development

article

Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury.

scientific article

Glial origin of mesenchymal stem cells in a tooth model system

scientific article published on 27 July 2014

Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium ⬇️

scientific article published on October 1, 1997

Hepatic stellate cells do not derive from the neural crest

scientific article published on 14 November 2005

Heterogeneity and phenotypic plasticity of glial cells in the mammalian enteric nervous system

scientific article published on 26 August 2014

Homeodomain proteins Mox1 and Mox2 associate with Pax1 and Pax3 transcription factors

scientific article (publication date: 22 June 2001)

III. Role Of the RET signal transduction pathway in development of the mammalian enteric nervous system.

scientific article published on August 1998

Immune and nervous systems: more than just a superficial similarity?

scientific article published in November 2009

Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis

scientific article published on 3 December 2015

Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice

scientific article published in September 1996

Interactions between Sox10, Edn3 and Ednrb during enteric nervous system and melanocyte development.

scientific article published on 3 April 2006

Isolation and characterization of a chicken homolog of the c-ret proto-oncogene.

scientific article published in February 1995

Isolation of the human MOX2 homeobox gene and localization to chromosome 7p22.1-p21.3.

scientific article

LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons

scientific article

Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton

scientific journal article

Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes

scientific journal article

Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep

scientific article published on 23 August 2017

Lhx8 regulates primordial follicle activation and postnatal folliculogenesis

scientific article published on 16 June 2015

Life without geminin

scientific article

Lineage-dependent spatial and functional organization of the mammalian enteric nervous system.

scientific article published in May 2017

Linking neurons to immunity: Lessons from Hydra

scientific article published on 05 August 2020

Locus unlinked to alpha-fetoprotein under the control of the murine raf and Rif genes

scientific article published on September 1984

Loss of forebrain cholinergic neurons and impairment in spatial learning and memory in LHX7-deficient mice

scientific journal article

Maintenance of mammalian enteric nervous system progenitors by SOX10 and endothelin 3 signalling.

scientific article published on 19 April 2006

Maturation-promoting activity of SATB1 in MGE-derived cortical interneurons

scientific article published on 8 November 2012

Meox1Cre: a mouse line expressing Cre recombinase in somitic mesoderm

scientific article published in November 2005

Microbiota controls the homeostasis of glial cells in the gut lamina propria

scientific article

Modulation of Apoptosis Controls Inhibitory Interneuron Number in the Cortex

scientific article published in February 2018

Mox2 is a component of the genetic hierarchy controlling limb muscle development

scientific journal article

Multipotential progenitors of the mammalian enteric nervous system capable of colonising aganglionic bowel in organ culture

scientific journal article

Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors

scientific article published on 12 June 2014

Neuroimmune regulation during intestinal development and homeostasis

scientific article

Neuron and glia generating progenitors of the mammalian enteric nervous system isolated from foetal and postnatal gut cultures

article

Non-cell-autonomous effects of Ret deletion in early enteric neurogenesis

scientific article

Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform

scientific article

Planar cell polarity genes control the connectivity of enteric neurons

scientific article

Prospective identification and isolation of enteric nervous system progenitors using Sox2.

scientific article

RET proto-oncogene is important for the development of respiratory CO2 sensitivity

scientific article

RET-deficient mice: an animal model for Hirschsprung's disease and renal agenesis

scientific article published in October 1995

RET/GFRα signals are dispensable for thymic T cell development in vivo

scientific article

Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons.

scientific article

Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex.

scientific article

Regulation of intestinal immunity and tissue repair by enteric glia

scientific article published on 20 October 2021

Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud development

article

Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis.

scientific article published on November 2002

Ret deficiency in mice impairs the development of A5 and A6 neurons and the functional maturation of the respiratory rhythm

scientific article published in November 2005

Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species

scientific article published in May 2008

Sex differences in water maze performance and cortical neurotrophin levels of LHX7 null mutant mice

scientific article published on 21 November 2008

Sexually dimorphic effects of the Lhx7 null mutation on forebrain cholinergic function

scientific article

Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut

scientific journal article

Spatial genetic patterning of the embryonic neuroepithelium generates GABAergic interneuron diversity in the adult cortex

scientific article published in October 2007

Structurally defined signaling in neuro-glia units in the enteric nervous system

scientific article published on 07 February 2019

Studies concerning the mechanism of suppression of renin secretion by clonidine ⬇️

scientific article published on March 1, 1975

Studies into the raf and Rif genes in the mouse

article

Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity

scientific article

Targeted disruption of the murine galanin gene.

scientific article

Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells.

scientific article published on 18 October 2006

The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous System

scientific article

The LIM homeodomain protein Lhx6 regulates maturation of interneurons and network excitability in the mammalian cortex

scientific article

The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition

scientific article published on 08 July 2009

The cell-intrinsic requirement of Sox6 for cortical interneuron development

scientific article

The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites

scientific journal article

The effect of the ret- mutation on the normal development of the central and parasympathetic nervous systems.

scientific article published in January 1996

The enteric nervous system

scientific article

The gut microbiota keeps enteric glial cells on the move; prospective roles of the gut epithelium and immune system

scientific article published on 11 November 2015

The influence of Hox genes and three intercellular signalling pathways on enteric neuromuscular development.

scientific article published on April 2004

The medial ganglionic eminence gives rise to a population of early neurons in the developing cerebral cortex.

scientific article

The structure and expression of a novel gene activated in early mouse embryogenesis ⬇️

scientific article published on March 1, 1988

The zebrafish homologue of the ret receptor and its pattern of expression during embryogenesis

scientific article published in February 1997

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

scientific article published on 11 October 2017

Transcription factor LIM homeobox 7 (Lhx7) maintains subtype identity of cholinergic interneurons in the mammalian striatum

scientific article published on 6 February 2012

Transcriptional regulation of cortical interneuron development.

scientific article published on October 2007

Transfer of a yeast artificial chromosome carrying human DNA from Saccharomyces cerevisiae into mammalian cells

scientific article

Transgenic overexpression of galanin in the dorsal root ganglia modulates pain-related behavior

scientific article

Travelling within the fetal gut: simple rules for an arduous journey

scientific article

Two regulatory domains flank the mouse H19 gene

scientific article published on November 1988

Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis

scientific journal article

Ventilatory responses to hypercapnia and hypoxia in heterozygous c-ret newborn mice

scientific article published in August 2002

White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies

scientific article

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