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List of works by Joerg Geiger

A Boolean view separates platelet activatory and inhibitory signalling as verified by phosphorylation monitoring including threshold behaviour and integrin modulation.

scientific article published on 6 March 2013

A comparative analysis of the bistability switch for platelet aggregation by logic ODE based dynamical modeling.

scientific article published in August 2014

A protein phosphorylation-based assay for screening and monitoring of drugs modulating cyclic nucleotide pathways.

scientific article

Deciphering of ADP‐induced, phosphotyrosine‐dependent signaling networks in human platelets by Src‐homology 2 region (SH2)‐profiling ⬇️

scientific article published on February 18, 2013

Defective nitrovasodilator-stimulated protein phosphorylation and calcium regulation in cGMP-dependent protein kinase-deficient human platelets of chronic myelocytic leukemia

scientific article published on 01 June 1993

Determination of ATP and ADP Secretion from Human and Mouse Platelets by an HPLC Assay.

scientific article published on 15 March 2013

Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: in vitro and in vivo/ex vivo studies

scientific article published on 30 January 2003

Dynamical modelling of prostaglandin signalling in platelets reveals individual receptor contributions and feedback properties

scientific article published in October 2013

Flow cytometry analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets--definition and detection of ticlopidine/clopidogrel effects

scientific article published on 01 September 1999

Human cyclic GMP-dependent protein kinase I beta overexpression increases phosphorylation of an endogenous focal contact-associated vasodilator-stimulated phosphoprotein without altering the thrombin-evoked calcium response

article

Insulin inhibition of platelet-endothelial interaction is mediated by insulin effects on endothelial cells without direct effects on platelets

scientific article published on 12 February 2008

Ligand specificity and ticlopidine effects distinguish three human platelet ADP receptors

scientific article

Low angle light scattering analysis: a novel quantitative method for functional characterization of human and murine platelet receptors

scientific article published on 01 July 2012

Megakaryocyte hyperplasia and enhanced agonist-induced platelet activation in vasodilator-stimulated phosphoprotein knockout mice.

scientific article

Multifaceted effects of arachidonic acid and interaction with cyclic nucleotides in human platelets

scientific article published on 13 September 2018

Phosphatidylserine surface expression and integrin alpha IIb beta 3 activity on thrombin/convulxin stimulated platelets/particles of different sizes

scientific article published on 20 November 2008

Platelet NAD(P)H-oxidase-generated ROS production regulates alphaIIbbeta3-integrin activation independent of the NO/cGMP pathway

scientific article published on 23 June 2005

Platelet-vessel wall interactions, focal adhesions, and the mechanism of action of endothelial factors.

scientific article

Potent inhibition of human platelets by cGMP analogs independent of cGMP-dependent protein kinase.

scientific article

Properties and regulation of human platelet cation channels.

scientific article

Quality Assessment of the Preanalytical Workflow in Liquid Biobanking: Taurine as a Serum-Specific Quality Indicator for Preanalytical Process Variations

scientific article published on 24 July 2019

Quantification of cAMP and cGMP analogs in intact cells: pitfalls in enzyme immunoassays for cyclic nucleotides ⬇️

scientific article published on June 29, 2011

Quantification of cAMP and cGMP analogs in intact cells: pitfals in enzyme immunoassays for cyclic nucleotides.

scientific article published in August 2011

Reciprocal regulation of human platelet function by endogenous prostanoids and through multiple prostanoid receptors

scientific article published on 6 July 2014

Regulation of calcium mobilization and entry in human platelets by endothelium-derived factors

scientific article published on 01 July 1994

Response: platelet transcriptome and proteome--relation rather than correlation.

scientific article published in June 2013

Robust Workflow for iTRAQ-Based Peptide and Protein Quantification

Specific PKG inhibitors: do they really exist?

scientific article published in August 2011

Standard PREanalytical Code version 3.0.

scientific article published on 29 January 2018

Temporal quantitative phosphoproteomics of ADP stimulation reveals novel central nodes in platelet activation and inhibition

scientific article published on 9 November 2016

The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable.

scientific article published on April 2016

The good, the bad, the ugly: validating the mass spectrometric analysis of modified peptides

scientific article published on 7 February 2011

The oligopeptide DT‐2 is a specific PKG I inhibitor only in vitro, not in living cells ⬇️

scientific article published on October 1, 2012

Thrombin stimulation of p38 MAP kinase in human platelets is mediated by ADP and thromboxane A2 and inhibited by cGMP/cGMP-dependent protein kinase

scientific article published on 21 September 2006

Time-resolved characterization of cAMP/PKA-dependent signaling reveals that platelet inhibition is a concerted process involving multiple signaling pathways.

scientific article

Time-resolved in silico modeling of fine-tuned cAMP signaling in platelets: feedback loops, titrated phosphorylations and pharmacological modulation.

scientific article

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