List of works by Martin Schmelz

A neural pathway for itch.

scientific article

A polymorphic locus in the intron 16 of the human angiotensin-converting enzyme (ACE) gene is not correlated with complex regional pain syndrome I (CRPS I).

scientific article published in June 2004

A study of serum concentrations and dermal levels of NGF in atopic dermatitis and healthy subjects

scientific article published on 3 September 2011

A subpopulation of capsaicin-sensitive porcine dorsal root ganglion neurons is lacking hyperpolarization-activated cyclic nucleotide-gated channels

scientific article published on 22 January 2008

ATP responses in human C nociceptors

scientific article published in July 2002

Abnormal Function of C-Fibers in Patients with Diabetic Neuropathy

scientific article published on 01 November 2006

Action potential conduction in the terminal arborisation of nociceptive C-fibre afferents

article published in 2003

Activation of Naloxone-Sensitive and -Insensitive Inhibitory Systems in a Human Pain Model

article

Acute Effects of Substance P and Calcitonin Gene-Related Peptide in Human Skin – A Microdialysis Study

article

Acute hyperinsulinemia differentially regulates interstitial and circulating adiponectin oligomeric pattern in lean and insulin-resistant, obese individuals

scientific article published on 9 October 2009

Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin

scientific article

Atopic keratinocytes induce increased neurite outgrowth in a coculture model of porcine dorsal root ganglia neurons and human skin cells

scientific article

Axon reflex flare and quantitative sudomotor axon reflex contribute in the diagnosis of small fiber neuropathy

scientific article published on 24 November 2012

Axonal hyperexcitability after combined NGF sensitization and UV-B inflammation in humans

scientific article published on 11 November 2013

Botulinum Toxin A reduces neurogenic flare but has almost no effect on pain and hyperalgesia in human skin.

scientific article published on February 2003

Bradykinin is a potent pruritogen in atopic dermatitis: A switch from pain to itch

scientific article published on 13 July 2006

Catecholamine release in human skin--a microdialysis study

scientific article

Catecholamine-induced excitation of nociceptors in sympathetically maintained pain

scientific article published on 25 September 2006

Chapter 18 Itch and cold allodynia

scientific article published on 01 January 2006

Chapter 29 Microneurography in the assessment of neuropathic pain

scientific article published on 01 January 2006

Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens

scientific article

Chemically and electrically induced sweating and flare reaction

scientific article

Chronic itch and pain--similarities and differences

scientific article

Clinical Classification of Itch: a Position Paper of the International Forum for the Study of Itch

article

Coculture model of sensory neurites and keratinocytes to investigate functional interaction: chemical stimulation and atomic force microscope-transmitted mechanical stimulation combined with live-cell imaging

scientific article published on 13 December 2012

Comparison of electrically induced flare response patterns in human and pig skin

scientific article

Complex interactions between pain and itch

scientific article published on 22 June 2006

Continuous brachial plexus blockade in combination with the NMDA receptor antagonist memantine prevents phantom pain in acute traumatic upper limb amputees

scientific article published on 22 May 2006

Corrigendum to “Inhibition of neutral endopeptidase (NEP) facilitates neurogenic inflammation” [Exp. Neurol. 195 (2005) 179–184]

scholarly article published in Experimental Neurology

Cross-over evaluation of electrically induced pain and hyperalgesia

scientific article published on 01 October 2010

Cross-sectional field 14 pain medicine. Implementation of the German Pain Society (DGSS) core curriculum in the model study course MaReCuM

scientific article published in August 2013

Cytokine profile in human skin in response to experimental inflammation, noxious stimulation, and administration of a COX-inhibitor: a microdialysis study

scientific article published on 8 April 2008

Delayed responses to electrical stimuli reflect C-fiber responsiveness in human microneurography

article

Delta-9-THC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief

scientific article

Density of sympathetic axons in sural nerve biopsies of neuropathy patients is related to painfulness

scientific article published on 01 February 2000

Different lipid profiles as constituencies of liquid formula diets do not influence pain perception and the efficacy of opioids in a human model of acute pain and hyperalgesia

scientific article published in August 2003

Different profiles of buprenorphine-induced analgesia and antihyperalgesia in a human pain model

scientific article

Differential central pain processing following repetitive intramuscular proton/prostaglandin E₂ injections in female fibromyalgia patients and healthy controls

scientific article published on 28 January 2011

Differential effects of lidocaine on nerve growth factor (NGF)-evoked heat- and mechanical hyperalgesia in humans

scientific article

Differential effects of low dose lidocaine on C-fiber classes in humans

scientific article

Differential endogenous pain modulation in complex-regional pain syndrome

scientific article

Differential modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by S-ketamine and clonidine in humans

scientific article

Differential sensitivity of thick and thin fibers to HIV and therapy-induced neuropathy

scientific article published on 11 June 2007

Differential sensitization of silent nociceptors to low pH stimulation by prostaglandin E2 in human volunteers

scientific article published on 30 May 2014

Discriminative sensory characteristics of the lateral femoral cutaneous nerve after mepivacaine-induced block

scientific article published on 01 April 2013

Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin

scientific article published on 01 June 2005

Does spontaneous activity in C-nociceptors provide a readout to quantify neuropathic pain?

scientific article published on 19 October 2011

Double spikes to single electrical stimulation correlates to spontaneous activity of nociceptors in painful neuropathy patients

scientific article published on 07 December 2011

Duration of effects of aspirin on platelet function in healthy volunteers: an analysis using the PFA-100

scientific article (publication date: February 2006)

Effects of COX inhibition on experimental pain and hyperalgesia during and after remifentanil infusion in humans

scientific article published on 10 March 2011

Effects of antihyperalgesic drugs on experimentally induced hyperalgesia in man.

scientific article

Effects of oral pregabalin and aprepitant on pain and central sensitization in the electrical hyperalgesia model in human volunteers

scientific article

Efficacy and safety of pregabalin in treatment refractory patients with various neuropathic pain entities in clinical routine

scientific article published on 24 September 2007

Electrically evoked itch in humans

scientific article

Electrically evoked neuropeptide release and neurogenic inflammation differ between rat and human skin

Electrically induced quantitative sudomotor axon reflex test in human volunteers

scientific article published on 01 January 2011

Electrically stimulated axon reflexes are diminished in diabetic small fiber neuropathies

scientific article

Endothelin 1 activates and sensitizes human C-nociceptors

scientific article published on 19 September 2007

Epidermal Nerve Fibers Modulate Keratinocyte Growth via Neuropeptide Signaling in an Innervated Skin Model

scientific article published on 03 January 2013

Evaluation of the effects of a metabotropic glutamate receptor 5-antagonist on electrically induced pain and central sensitization in healthy human volunteers

scientific article published on 6 May 2013

Experimental thermal lesions induce beta-thromboglobulin release from activated platelets

scientific article published on 26 May 2010

Facilitated neurogenic inflammation in complex regional pain syndrome.

scientific article

Facilitated neurogenic inflammation in unaffected limbs of patients with complex regional pain syndrome

scientific article published in April 2004

Facilitated neurotrophin release in sensitized human skin

scientific article published on 20 June 2008

Frontiers in pruritus research: scratching the brain for more effective itch therapy

scientific article

Hematopoietic colony–stimulating factors mediate tumor-nerve interactions and bone cancer pain

scientific article published on 07 June 2009

High spontaneous activity of C-nociceptors in painful polyneuropathy

scientific article published on 01 October 2012

How pain becomes itch.

scientific article published on 20 May 2009

Human in-vivo bioassay for the tissue-specific measurement of nociceptive and inflammatory mediators

scientific article published on December 2008

Hyperinsulinemia and insulin resistance in the obese may develop as part of a homeostatic response to elevated free fatty acids: A mechanistic case-control and a population-based cohort study

scientific article published on 09 March 2021

Impaired Delivery of Insulin to Adipose Tissue and Skeletal Muscle in Obese Women with Postprandial Hyperglycemia

scientific article published on 15 June 2011

In situ profiling of adipokines in subcutaneous microdialysates from lean and obese individuals

scientific article

Inflammation meets sensitization--an explanation for spontaneous nociceptor activity?

scientific article published on 8 August 2013

Injection pain of rocuronium and vecuronium is evoked by direct activation of nociceptive nerve endings.

scientific article

Interaction of Pruritus and Pain

Interaktionen von Juckreiz und Schmerz

scientific article published on 01 May 2006

Interleukin-6 in combination with its soluble IL-6 receptor sensitises rat skin nociceptors to heat, in vivo

scientific article published on 01 March 2002

Intracutaneous injections of platelets cause acute pain and protracted hyperalgesia

scientific article published on 01 May 1997

Itch

scientific article

Itch and pain

scientific article published on 25 December 2008

Itch without pain—a labeled line for itch sensation?

scientific article published on 01 December 2009

Klinische Klassifikation von chronischem Pruritus

scientific article published on 01 May 2006

Local gene expression changes after UV-irradiation of human skin

scientific article (publication date: 2012)

Local nociceptor sensitization with NGF: mechanical or heat hyperalgesia á la carte?

scientific article

Long-acting local anesthetics attenuate FMLP-induced acute lung injury in rats

scientific article published in September 2009

Low-dose lidocaine reduces secondary hyperalgesia by a central mode of action

scientific article

Low-dose lidocaine suppresses experimentally induced hyperalgesia in humans

scientific article published in December 1998

Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients: a dermal microdialysis study.

scientific article

Maximum axonal following frequency separates classes of cutaneous unmyelinated nociceptors in the pig

scientific article published on 28 December 2020

Mechanically induced axon reflex and hyperalgesia in human UV-B burn are reduced by systemic lidocaine

scientific article published in June 2004

Mechano-insensitive nociceptors are sufficient to induce histamine-induced itch

scientific article published in July 2013

Mechano-insensitive nociceptors encode pain evoked by tonic pressure to human skin

scientific article published on 01 January 2000

Microneurographic assessment of C-fibre function in aged healthy subjects

article by B Namer et al published 15 January 2009 in Journal of Physiology

Microneurographic single-unit recordings to assess receptive properties of afferent human C-fibers

scientific article (publication date: 19 February 2010)

Modality-Specific Nociceptor Sensitization Following UV-B Irradiation of Human Skin

scientific article published on 30 April 2013

Modeling activity-dependent changes of axonal spike conduction in primary afferent C-nociceptors

scientific article published on 26 December 2013

Modern aspects of cutaneous neurogenic inflammation.

scientific article published on November 2003

Modulation of Pruritus: Peripheral and Central Sensitisation

Modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by parecoxib in humans

scientific article published in November 2006

Monocyte chemoattractant protein-1 in subcutaneous abdominal adipose tissue: characterization of interstitial concentration and regulation of gene expression by insulin

scientific article published on 24 April 2007

NGF enhances electrically induced pain, but not axon reflex sweating

scientific article published on 4 May 2011

NGF induces non-inflammatory localized and lasting mechanical and thermal hypersensitivity in human skin

NGF sensitizes nociceptors for cowhage- but not histamine-induced itch in human skin

scientific article published on 26 July 2012

NGF-evoked sensitization of muscle fascia nociceptors in humans

scientific article published on 15 June 2012

Naloxone provokes similar pain facilitation as observed after short-term infusion of remifentanil in humans

scientific article published in November 2003

Nerve growth factor induces sensitization of nociceptors without evidence for increased intraepidermal nerve fiber density

scientific article published on 26 July 2013

Nerve growth factor selectively decreases activity-dependent conduction slowing in mechano-insensitive C-nociceptors

scientific article published on 18 July 2011

Nerve growth factor-evoked nociceptor sensitization in pig skin in vivo

Neural activation during experimental allodynia: a functional magnetic resonance imaging study

scientific article

Neural fractalkine expression is closely linked to pain and pancreatic neuritis in human chronic pancreatitis

scientific article published on 19 January 2009

Neurogenic Inflammation in Complex Regional Pain Syndrome (CRPS)

Neurogenic components of trypsin- and thrombin-induced inflammation in rat skin, in vivo

scientific article

Neuronal sensitivity of the skin

scientific article published on May 2011

Neuronal sensitization for histamine-induced itch in lesional skin of patients with atopic dermatitis

scientific article published in November 2003

Neuropeptides, neurogenic inflammation and complex regional pain syndrome (CRPS).

scientific article published on 30 March 2008

Neurophysiological evidence for altered sensory function caused by storage of hydroxyethyl starch in cutaneous nerve fibres.

scientific article published in May 2005

Neurophysiological, neuroimmunological, and neuroendocrine basis of pruritus

scientific article

Neurophysiology of pruritus: cutaneous elicitation of itch

scientific article published on November 2003

Neurophysiology of pruritus: interaction of itch and pain.

scientific article published on November 2003

Neurotrophins in the cerebrospinal fluid of patient cohorts with neuropathic pain, nociceptive pain, or normal pressure hydrocephalus

scientific article

No alpha-adrenoreceptor-induced C-fiber activation in healthy human skin

scientific article

Nociceptor sensitization to mechanical and thermal stimuli in pig skin in vivo

scientific article

Objective assessment of C-fiber function by electrically induced axon reflex flare in patients with axonal and demyelinating polyneuropathy

scientific article

Opioidinduzierter Pruritus

scientific article published on 01 January 2009

Opioids and the skin: "itchy" perspectives beyond analgesia and abuse

scientific article published on June 2007

Pain and inflammatory hyperalgesia induced by intradermal injections of human platelets and leukocytes.

scientific article published in June 1999

Painful and Nonpainful Phantom and Stump Sensations in Acute Traumatic Amputees

scientific article published on 01 October 2008

Pathogenese des Pruritus

scientific article published on 24 May 2011

Pathogenesis of pruritus

article published in 2011

Pathological C-fibres in patients with a chronic painful condition

scientific article published in March 2003

Pathophysiology and treatment of pain in joint disease

scientific article

Patterns of activity-dependent conduction velocity changes differentiate classes of unmyelinated mechano-insensitive afferents including cold nociceptors, in pig and in human

scientific article published on 13 November 2009

Percutaneous penetration studies for risk assessment

scientific article published on 01 January 2000

Peripheral antihyperalgesic effect of morphine to heat, but not mechanical, stimulation in healthy volunteers after ultraviolet-B irradiation.

scientific article published in January 1999

Pituitary adenylate cyclase activating polypeptide: an important vascular regulator in human skin in vivo.

scientific article

Plasma extravasation and neuropeptide release in human skin as measured by intradermal microdialysis

scientific article published on 01 July 1997

Polyneuropathy induced by HIV disease and antiretroviral therapy

scientific article

Post-junctional facilitation of Substance P signaling in a tibia fracture rat model of complex regional pain syndrome type I.

scientific article published on 21 May 2009

Postprandial interstitial insulin concentrations in type 2 diabetes relatives

scientific article published on 01 June 2006

Potentiation of nociceptive responses to low pH injections in humans by prostaglandin E2

scientific article

Predominant CB2 receptor expression in endothelial cells of glioblastoma in humans

scientific article published on 6 February 2009

Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo

scientific article published in October 2003

Prostaglandin E2 induces vasodilation and pruritus, but no protein extravasation in atopic dermatitis and controls

scientific article

Rapid flare development evoked by current frequency-dependent stimulation analyzed by full-field laser perfusion imaging

scientific article

Reduction of pulmonary edema by short-acting local anesthetics

scientific article published in May 2006

Representation of UV-B-induced thermal and mechanical hyperalgesia in the human brain: a functional MRI study

scientific article

Respiratorische Insuffizienz durch Delta-9-Tetrahydrocannabinol bei tetraplegischem Patienten

scientific article published on 01 November 2006

Response to the “Letter to the Editor of Pain” by Prof. J. Ochoa

article published in 2007

Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury

scientific article published on 25 April 2008

Schmerzchronifizierung

Schmerzen und Jucken

scientific article published on 01 July 2012

Schwann Cell Autocrine and Paracrine Regulatory Mechanisms, Mediated by Allopregnanolone and BDNF, Modulate PKCε in Peripheral Sensory Neurons

scientific article published on 11 August 2020

Selective thoracic ganglionectomy for the treatment of segmental neuropathic pain

scientific article

Sensitivity of human scalp skin to pruritic stimuli investigated by intradermal microdialysis in vivo

scientific article

Sensitization to bradykinin B1 and B2 receptor activation in UV-B irradiated human skin

scientific article

Sensitized pain response to bradykinin after sunburn - a human model for ongoing inflammatory pain?

scientific article published on 15 March 2013

Separate peripheral pathways for pruritus in man

scientific article published on 18 June 2008

Sex differences in itch perception and modulation by distraction--an FMRI pilot study in healthy volunteers

scientific article

Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal

scientific article

Single-Unit Recordings of Afferent Human Peripheral Nerves by Microneurography

Single-fiber recordings of unmyelinated afferents in pig.

scientific article published on 08 October 2009

Skin innervation at different depths correlates with small fibre function but not with pain in neuropathic pain patients

scientific article published on 03 May 2012

Sodium Channel Nav1.8 Underlies TTX-Resistant Axonal Action Potential Conduction in Somatosensory C-Fibers of Distal Cutaneous Nerves

scientific article published on 27 April 2017

Sphingosine-1-phosphate-induced nociceptor excitation and ongoing pain behavior in mice and humans is largely mediated by S1P3 receptor

scientific article published in February 2013

Structural and functional differences between neuropathy with and without pain?

scientific article published on 13 June 2011

Substance-P-induced protein extravasation is bilaterally increased in complex regional pain syndrome

scientific article published on 01 September 2003

Sunburn—A human inflammatory pain model for primary and secondary hyperalgesia

scientific article published on 01 January 2013

The cyclooxygenase isozyme inhibitors parecoxib and paracetamol reduce central hyperalgesia in humans

scientific article

The differential effects of two sodium channel modulators on the conductive properties of C-fibers in pig skin in vivo

scientific article

The effect of intravenous infusion of adenosine on electrically evoked hyperalgesia in a healthy volunteer model of central sensitization

scientific article

The effect of the nitric oxide synthase inhibitor N-nitro-L-arginine-methyl ester on neuropeptide-induced vasodilation and protein extravasation in human skin

scientific article

The impact of opioid-induced hyperalgesia for postoperative pain

scientific article published on March 2007

The neurobiology of itch

scientific article (publication date: July 2006)

Thoracoscopic sympathectomy at the T2 or T3 level facilitates bradykinin-induced protein extravasation in human forearm skin

scientific article

Time course of UVA- and UVB-induced inflammation and hyperalgesia in human skin.

scientific article

Time course of acetylcholine-induced activation of sympathetic efferents matches axon reflex sweating in humans

scientific article

Topical acetyl salicylate and dipyrone attenuate neurogenic protein extravasation in rat skin in vivo

scientific article published on 01 August 2000

Topical acetylsalicylate attenuates capsaicin induced pain, flare and allodynia but not thermal hyperalgesia

Transcutaneous penetration of toluene in rat skin a microdialysis study

scientific article

Translating nociceptive processing into human pain models

scientific article published on 29 April 2009

[Mechanisms in the development of pain. Key issue in the periphery].

scientific article published in October 2005

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