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List of works by Sandor Benyhe

14-O-Methylmorphine: A Novel Selective Mu-Opioid Receptor Agonist with High Efficacy and Affinity

scientific article published on 29 August 2017

A monoclonal antibody recognizing kappa- but not mu- and delta-opioid receptors.

scientific article published on June 1991

Affinity labelling of frog brain opioid receptors by dynorphin(1-10) chloromethyl ketone

scientific article published in February 1997

Agonist-dependent attenuation of mu-opioid receptor-mediated G-protein activation in the dorsal root ganglia of neuropathic rats

scientific article published on 6 March 2010

Alkamides and a neolignan from Echinacea purpurea roots and the interaction of alkamides with G-protein-coupled cannabinoid receptors.

scientific article published on 19 July 2011

Altered gene expression and functional activity of opioid receptors in the cerebellum of CB1 cannabinoid receptor knockout mice after acute treatments with cannabinoids.

scientific article

Antinociceptive effect induced by a combination of opioid and neurotensin moieties vs. their hybrid peptide [Ile(9)]PK20 in an acute pain treatment in rodents.

scientific article

Binding characteristics and analgesic activity of D-ALA2-Leu5-enkephalin chloromethyl ketone

scientific article published in June 1983

Binding studies of novel, non-mammalian enkephalins, structures predicted from frog and lungfish brain cDNA sequences

scientific article published on 10 October 2008

Bioactivity studies on atypical natural opioid hexapeptides processed from proenkephalin (PENK) precursor polypeptides.

scientific article

Bioinformatic and biochemical studies on the phylogenetic variability of proenkephalin-derived octapeptides

scientific article

Biological evaluation and molecular docking studies of AA3052, a compound containing a μ-selective opioid peptide agonist DALDA and d-Phe-Phe-d-Phe-Leu-Leu-NH2, a substance P analogue.

scientific article published on 13 July 2016

Blood-brain transfer and antinociception of linear and cyclic N-methyl-guanidine and thiourea-enkephalins

scientific article published on 4 November 2014

CB(2) cannabinoid receptor antagonist SR144528 decreases mu-opioid receptor expression and activation in mouse brainstem: role of CB(2) receptor in pain.

scientific article

Changes in the cannabinoid (CB1) receptor expression level and G-protein activation in kainic acid induced seizures ⬇️

scientific article published on November 10, 2011

Characterization of [3H] oxymorphone binding sites in mouse brain: Quantitative autoradiography in opioid receptor knockout mice.

scientific article published on 9 February 2017

Characterization of [3H]Met-enkephalin-Arg6-Phe7 binding to multiple sites in rat and guinea pig cerebellum

scientific article published in January 1999

Characterization of kappa 1 and kappa 2 opioid binding sites in frog (Rana esculenta) brain membrane preparation

scientific article

Characterization of rat brain opioid receptors by [Tyr-3,5-3H]1, D-Ala2, Leu5-enkephalin binding

scientific article

Cloning and characterization of Xen-dorphin prohormone from Xenopus laevis: a new opioid-like prohormone distinct from proenkephalin and prodynorphin

scientific article

Comparative biochemical and pharmacological characterization of a novel, NOP receptor selective hexapeptide, Ac-RYYRIR-ol.

scientific article published on 2 October 2009

Covalent labeling of opioid receptors with 3H-D-Ala2-Leu5-enkephalin chloromethyl ketone. II. Binding characteristics in frog brain membranes

scientific article published in July 1987

Cyclic Biphalin Analogues Incorporating a Xylene Bridge: Synthesis, Characterization, and Biological Profile.

scientific article

Cyclic enkephalins with a diversely substituted guanidine bridge or a thiourea bridge: synthesis, biological and structural evaluations

scientific article published on 12 July 2013

Decreased CB receptor binding and cannabinoid signaling in three brain regions of a rat model of schizophrenia

scientific article published on 14 September 2016

Design, Synthesis and Biological Evaluation of Two Opioid Agonist and Cav 2.2 Blocker Multitarget Ligands

scientific article published on 8 December 2014

Discovery of Novel µ-Opioid Receptor Inverse Agonist from a Combinatorial Library of Tetrapeptides through Structure-Based Virtual Screening

scientific article published on 27 October 2019

Effect of alpha-adrenoceptor subtype-selective inverse agonists on non-pregnant and late-pregnant cervical resistance in vitro in the rat.

scientific article

Effect of sodium on [3H]ethylketocyclazocine binding to opioid receptors in frog brain membranes

scientific article

Endomorphin-2 with a beta-turn backbone constraint retains the potent micro-opioid receptor agonist properties.

scientific article

Ethylketocyclazocine and N-cyclopropylmethyl-norazidomorphine are antagonists of morphine-induced analgesia in frog spinal cord

scientific article published on 01 February 1988

Evaluation of the analgesic effect of 4-anilidopiperidine scaffold containing ureas and carbamates.

scientific article published on 11 April 2016

Exploring the first Rimonabant analog-opioid peptide hybrid compound, as bivalent ligand for CB1 and opioid receptors

scientific article

Further Characterization of Hemopressin Peptide Fragments in the Opioid and Cannabinoid Systems

scientific article published on 13 October 2015

Homology modeling and phylogenetic relationships of catalases of an opportunistic pathogen Rhizopus oryzae

scientific article published on 28 June 2012

Hybrid peptides endomorphin-2/DAMGO: design, synthesis and biological evaluation.

scientific article published on 11 August 2013

In vitro and in vivo pharmacological characterization of the nociceptin/orphanin FQ receptor ligand Ac-RYYRIK-ol.

scientific article published on 5 April 2006

In vitro binding and functional studies of Ac-RYYRIK-ol and its derivatives, novel partial agonists of the nociceptin/orphanin F/Q receptor

scientific article published on 26 July 2006

In vitro binding and signaling profile of the novel mu opioid receptor agonist endomorphin 2 in rat brain membranes

scientific article published in September 1998

Inflammatory processes enhance cAMP-mediated uterus relaxation in the pregnant rat: the role of TNF-alpha

scientific article

Inhibition of forebrain μ-opioid receptor signaling by low concentrations of rimonabant does not require cannabinoid receptors and directly involves μ-opioid receptors ⬇️

scientific article published on May 18, 2012

Interactions between the Kynurenine and the Endocannabinoid System with Special Emphasis on Migraine

scientific article published on 30 July 2017

Irreversible blockade of the high and low affinity (3H) naloxone binding sites by C-6 derivatives of morphinane-6-ones

scientific article published on 01 January 1991

Irreversible labelling of the opioid receptors by a melphalan-substituted [Met5]enkephalin-Arg-Phe derivative

scientific article published in June 1999

Kainic acid-induced changes in the opioid/nociceptin system and the stress/toxicity pathways in the rat hippocampus.

scientific article published on 21 February 2012

Kainic acid-induced seizure activity alters the mRNA expression and G-protein activation of the opioid/nociceptin receptors in the rat brain cortex

scientific article

Kappa-receptor selective binding of opioid ligands with a heterocyclic bicyclo[3.3.1]nonan-9-one structure

scientific article

Kinetics and physical parameters of rat brain opioid receptors solubilized by digitonin and CHAPS.

scientific article published in March 1986

Kynurenic acid and its analogue can alter the opioid receptor G-protein signaling after acute treatment via NMDA receptor in rat cortex and striatum

scientific article

Low dosage of rimonabant leads to anxiolytic-like behavior via inhibiting expression levels and G-protein activity of kappa opioid receptors in a cannabinoid receptor independent manner.

scientific article

Micromolar concentrations of rimonabant directly inhibits delta opioid receptor specific ligand binding and agonist-induced G-protein activity.

scientific article published on 4 February 2014

Morphine: new aspects in the study of an ancient compound.

scientific article published on January 1994

Mu opioid receptor mRNA expression, binding, and functional coupling to G-proteins in human epileptic hippocampus.

scientific article published on 3 November 2010

Mu-Opioid (MOP) receptor mediated G-protein signaling is impaired in specific brain regions in a rat model of schizophrenia.

scientific article

New opioid receptor antagonist: Naltrexone-14-O-sulfate synthesis and pharmacology.

scientific article published on 11 May 2017

Nociceptin binding sites in frog (Rana esculenta) brain membranes.

scientific article

Nociceptin inhibits uterine contractions in term-pregnant rats by signaling through multiple pathways

scientific journal article

Noladin ether, a putative endocannabinoid, inhibits mu-opioid receptor activation via CB2 cannabinoid receptors.

scientific article published on 04 July 2007

Non-opioid actions of opioid peptides.

scientific article

Novel cyclic biphalin analogue with improved antinociceptive properties.

scientific article published on 14 July 2014

Novel diastereomeric opioid tetrapeptides exhibit differing pharmacological activity profiles.

scientific article

Novel opioid-neurotensin-based hybrid peptide with spinal long-lasting antinociceptive activity and a propensity to delay tolerance development

scientific article published on 01 May 2020

Opioid Receptor Activity and Analgesic Potency of DPDPE Peptide Analogues Containing a Xylene Bridge.

scientific article published on 14 March 2017

Opioid binding profile of morphiceptin, Tyr-MIF-1 and dynorphin-related peptides in rat brain membranes

scientific article

Opioid receptor binding characteristics and structure-activity studies of novel tetrapeptides in the TIPP (Tyr-Tic-Phe-Phe) series.

scientific article published in January 2005

Opioid receptor labeling with the chloromethyl ketone derivative of [3H]Tyr-D-Ala-Gly-(Me)Phe-Gly-ol (DAMGO) II: Covalent labeling of mu opioid binding site by 3H-Tyr-D-Ala-Gly-(Me)Phe chloromethyl ketone.

scientific article

Partial and full agonism in endomorphin derivatives: comparison by null and operational model.

scientific article published on 18 January 2006

Pharmacological and functional biochemical properties of D-Ala2-D-Nle5-enkephalin-Arg-Phe

scientific article published in October 2004

Phylogenetic diversity and functional efficacy of the C-terminally expressed heptapeptide unit in the opioid precursor polypeptide proenkephalin A.

scientific article

Pregnancy-induced decrease in the relaxant effect of terbutaline in the late-pregnant rat myometrium: role of G-protein activation and progesterone

scientific article published in July 2005

Promitogenic effects of ethanol, methanol, and ethanolamine in insulin-treated fibroblasts.

scientific article published on November 2000

Purification of a kappa-opioid receptor subtype from frog brain

scientific article

Receptor binding and G-protein activation by new Met5-enkephalin-Arg6-Phe7 derived peptides

scientific article published on 01 February 2000

Receptor constants for endomorphin-1 and endomorphin-1-ol indicate differences in efficacy and receptor occupancy

scientific article published in June 2001

Restraint stress and anti-tumor immune response in mice

scientific article published in January 2003

Selective and high affinity labeling of neuronal and recombinant nociceptin receptors with the hexapeptide radioprobe [(3)H]Ac-RYYRIK-ol.

scientific article published on 4 May 2009

Separation of kappa-opioid receptor subtype from frog brain

scientific article

Solubilization and characterization of opioid binding sites from frog (Rana esculenta) brain

scientific article published in October 1984

Structurally novel group of ligands selective for kappa opioid receptors

Structure-activity study on the Phe side chain arrangement of endomorphins using conformationally constrained analogues

scientific article published in January 2004

Synthesis and binding characteristics of [(3)H]neuromedin N, a NTS2 receptor ligand

scientific article

Synthesis and binding characteristics of a novel enkephalin analogue, [3H]Tyr-D-Ala-Gly-Phe-D-Nle-Arg-Phe

scientific article

Synthesis and biological studies of nociceptin derivatives containing the DTPA chelating group for further labeling with therapeutic radionuclides

scientific article published on 2 March 2005

Synthesis of 3H-Tyr-D-Ala-Gly-N(Me)Phe chloromethyl ketone--an opioid affinity label

scientific article

Synthesis of enzymatically resistant nociceptin-related peptides containing a carbamic acid residue

scientific article published in July 2006

Temporal lobe epilepsy causes selective changes in mu opioid and nociceptin receptor binding and functional coupling to G-proteins in human temporal neocortex

scientific article

Terbutaline increases the cervical resistance of the pregnant rat in vitro

scientific article published on 12 January 2005

The effects of estrogen on the α2-adrenergic receptor subtypes in rat uterine function in late pregnancy in vitro

scientific article published on April 2016

The effects of female sexual hormones on the expression and function of α1A- and α1D-adrenoceptor subtypes in the late-pregnant rat myometrium

scientific article published on 16 November 2015

The effects of progesterone on the alpha2-adrenergic receptor subtypes in late-pregnant uterine contractions in vitro

scientific article published on 14 June 2016

Tyr-D-Ala-Gly-(Me)Phe-chloromethyl ketone: a mu specific affinity label for the opioid receptor

scientific article published in April 1987

Xendorphin B1, a novel opioid-like peptide determined from a Xenopus laevis brain cDNA library, produces opioid antinociception after spinal administration in amphibians

scientific article

[3H]dynorphin1-8 binding sites in frog (Rana esculenta) brain membranes

scientific article published in May 1994

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