List of works by Mark A. Connor

A continuous, fluorescence-based assay of μ-opioid receptor activation in AtT-20 cells

scientific article

A real-time, fluorescence-based assay for measuring μ-opioid receptor modulation of adenylyl cyclase activity in Chinese hamster ovary cells

scientific article

A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro.

scientific article

Absence of Entourage: Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Functional Activity of Δ9-THC at Human CB1 and CB2 Receptors

scientific article published on 23 September 2019

Accelerating the search for the missing proteins in the human proteome

scientific article published on 24 January 2017

Actions of cannabinoids on membrane properties and synaptic transmission in rat periaqueductal gray neurons in vitro

article

Actions of nociceptin/orphanin FQ and other prepronociceptin products on rat rostral ventromedial medulla neurons in vitro

scientific article

Allopurinol for pain relief: more than just crystal clearance?

scientific article

Bradykinin inhibition of N- and L-type calcium channel currents in NG108-15 cells.

scientific article published in January 1997

Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells

scientific article published on 25 September 2019

Buprenorphine signalling is compromised at the N40D polymorphism of the human μ opioid receptor in vitro

scientific article

Cannabichromene is a cannabinoid CB2 receptor agonist

scientific article published on 21 November 2019

Cannabinoid CB1 and CB2 Receptor Signaling and Bias

scientific article

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.

scientific article published on 03 January 2017

Cellular actions of somatostatin on rat periaqueductal grey neurons in vitro.

scientific article

Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1)

scientific article

Chronic ethanol promotes the neuronal differentiation of NG108-15 cells independently of toxin-sensitive G-proteins

scientific article

Conformationally rigid derivatives of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin-1a receptors.

scientific article published on 23 October 2017

Constitutively active μ-opioid receptors

scientific article published on January 2010

Contrasting phenotypes of putative proprioceptive and nociceptive trigeminal neurons innervating jaw muscle in rat

scientific article

Convulsant actions of calycanthine

scientific article published in July 2003

Cortistatin increase of a potassium conductance in rat locus coeruleus in vitro.

scientific article published in December 1997

Dark Classics in Chemical Neuroscience: Δ9-Tetrahydrocannabinol

scientific article published on 22 February 2019

Decreased mu-opioid receptor signalling and a reduction in calcium current density in sensory neurons from chronically morphine-treated mice.

scientific article published on 19 June 2006

Development of Bright and Biocompatible Nanoruby and Its Application to Background-Free Time-Gated Imaging of G-Protein-Coupled Receptors

scientific article

Differential activation of G protein-mediated signaling by synthetic cannabinoid receptor agonists

scientific article published on 01 April 2020

Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge

scientific article published in June 2000

Discovery and structure of a potent and highly specific blocker of insect calcium channels

scientific article

Distinct Temporal Fingerprint for Cyclic Adenosine Monophosphate (cAMP) Signaling of Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid Receptors.

scientific article published on 23 July 2015

Effects of bioisosteric fluorine in synthetic cannabinoid designer drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135.

scientific article

Exploring Stereochemical and Conformational Requirements at Cannabinoid Receptors for Synthetic Cannabinoids Related to SDB-006, 5F-SDB-006, CUMYL-PICA, and 5F-CUMYL-PICA

scientific article published on 15 October 2020

Flexible analogues of WAY-267,464: Synthesis and pharmacology at the human oxytocin and vasopressin 1a receptors

scientific article published on 13 December 2015

Fluorescence-based, high-throughput assays for μ-opioid receptor activation using a membrane potential-sensitive dye.

scientific article

Focal stimulation of specific pathways in the rat hippocampus causes a reduction in radioligand binding to the haloperidol-sensitive sigma receptor ⬇️

scientific article published on January 1, 1991

Frequency-dependent neuromuscular blockade by textilotoxin in vivo

scientific article published on 01 January 1991

Gingerols: a novel class of vanilloid receptor (VR1) agonists

scientific article

Has the sun set on kappa3-opioid receptors?

scientific article published on February 2006

High-resolution solution structure of gurmarin, a sweet-taste-suppressing plant polypeptide

scientific article

How opioids inhibit GABA-mediated neurotransmission

scientific article

Humanizing mice: catching up with elusive B1 receptors.

scientific article

Identification of N-arachidonoyl dopamine as a highly biased ligand at cannabinoid CB1 receptors

scientific article published on 23 September 2015

In search of a role for the morphine metabolite morphine-3-glucuronide

scientific article published in August 2003

In vitro determination of the efficacy of illicit synthetic cannabinoids at CB1 receptors

scientific article published on 10 December 2019

Inhibition of human recombinant T-type calcium channels by N-arachidonoyl 5-HT

scientific article

Inhibition of human recombinant T-type calcium channels by the endocannabinoid N-arachidonoyl dopamine

scientific article

Inhibition of recombinant human T-type calcium channels by Delta9-tetrahydrocannabinol and cannabidiol

scientific article published on 7 April 2008

Investigation of pyrazolo-sulfonamides as putative small molecule oxytocin receptor agonists

scientific article

Isolation and pharmacological characterisation of delta-atracotoxin-Hv1b, a vertebrate-selective sodium channel toxin

scientific article published in March 2000

Isolation of a funnel-web spider polypeptide with homology to mamba intestinal toxin 1 and the embryonic head inducer Dickkopf-1.

scientific article published in March 2000

Lack of functional expression of NMDA receptors in PC12 cells.

scientific article

Ligand determinants of fatty acid activation of the pronociceptive ion channel TRPA1.

scientific article published on 28 January 2014

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists

scientific article published on 31 March 2020

Methanandamide activation of a novel current in mouse trigeminal ganglion sensory neurons in vitro

scientific article

Modulation of Ca2+ channel currents of acutely dissociated rat periaqueductal grey neurons

scientific article published in May 1998

Mu-opioid receptor desensitization: is morphine different?

scientific article published on 25 October 2004

Mu-opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR-1.

scientific article

Neuropeptide Y Y2 receptor and somatostatin sst2 receptor coupling to mobilization of intracellular calcium in SH-SY5Y human neuroblastoma cells.

scientific article published on February 1997

Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse

scientific article

Nociceptin, Phe(1)psi-nociceptin(1 - 13), nocistatin and prepronociceptin(154 - 181) effects on calcium channel currents and a potassium current in rat locus coeruleus in vitro.

scientific article

Nordihydroguaiaretic acid activates hTRPA1 and modulates behavioral responses to noxious cold in mice

scientific article

Oocytes from Xenopus laevis contain an intrinsic sigma 2-like binding site

scientific article published in October 1994

Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors

scientific article

Opioid receptor signalling mechanisms.

scientific article

Opioid tolerance in periaqueductal gray neurons isolated from mice chronically treated with morphine

scientific article

Opioids: cellular mechanisms of tolerance and physical dependence

scientific article

Pharmacological characterization of a recombinant, fluorescent somatostatin receptor agonist.

scientific article

Pharmacology of Cumyl-Carboxamide Synthetic Cannabinoid New Psychoactive Substances (NPS) CUMYL-BICA, CUMYL-PICA, CUMYL-5F-PICA, CUMYL-5F-PINACA, and Their Analogues.

scientific article published on 9 August 2017

Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA.

scientific article

Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and Their Analogues

scientific article

Polysialic Acid Regulates Sympathetic Outflow by Facilitating Information Transfer within the Nucleus of the Solitary Tract.

scientific article published on 2 June 2017

Prostaglandin E(2) inhibits calcium current in two sub-populations of acutely isolated mouse trigeminal sensory neurons.

scientific article published in March 2002

Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action

scientific article published on October 2013

Regulation of heterologously expressed 5-HT1B receptors coupling to potassium channels in AtT-20 cells

scientific article published on 28 December 2018

Sex differences in the expression of serotonin-synthesizing enzymes in mouse trigeminal ganglia

scientific article published on 26 October 2011

Shadows across mu-Star? Constitutively active mu-opioid receptors revisited

scientific article published on April 2009

Single nucleotide polymorphisms in the cannabinoid CB 2 receptor: Molecular pharmacology and disease associations

scientific article published on 27 May 2024

Strategies to develop selective CB2 receptor agonists from indole carboxamide synthetic cannabinoids

scientific article published on 11 July 2019

Structure–activity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologues

Sumatriptan inhibits synaptic transmission in the rat midbrain periaqueductal grey.

scientific article published on 11 November 2008

Synthesis and Pharmacological Profiling of the Metabolites of Synthetic Cannabinoid Drugs APICA, STS-135, ADB-PINACA, and 5F-ADB-PINACA.

scientific article published on 2 June 2017

Synthesis and in vitro evaluation of fluorine-18 benzimidazole sulfones as CB2 PET-radioligands

scientific article published on 09 May 2019

Synthesis and pharmacology of new psychoactive substance 5F-CUMYL-P7AICA, a scaffold- hopping analog of synthetic cannabinoid receptor agonists 5F-CUMYL-PICA and 5F-CUMYL-PINACA

scientific article published on 01 October 2018

TRPV1 antagonists as a potential treatment for hyperalgesia.

scientific article published on January 2006

Targeting somatostatin receptors using in situ-bioconjugated fluorescent nanoparticles.

scientific article

Terpenoids Commonly Found in <i>Cannabis sativa</i> Do Not Modulate the Actions of Phytocannabinoids or Endocannabinoids on TRPA1 and TRPV1 Channels

scientific article published on 15 December 2020

The 2-alkyl-2H-indazole regioisomers of synthetic cannabinoids AB-CHMINACA, AB-FUBINACA, AB-PINACA, and 5F-AB-PINACA are possible manufacturing impurities with cannabimimetic activities

scientific article published on 27 April 2016

The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonist New Psychoactive Substances: Evolution

scientific article published on 01 January 2018

The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonists as New Psychoactive Substances: Origins

scientific article published on 01 January 2018

The Concise Guide to PHARMACOLOGY 2013/14: overview

scientific article

The Concise Guide to PHARMACOLOGY 2015/16: Overview

scientific article

The chemistry and pharmacology of putative synthetic cannabinoid receptor agonist (SCRA) new psychoactive substances (NPS) 5F-PY-PICA, 5F-PY-PINACA, and their analogs

scientific article published on 08 May 2019

The chemistry and pharmacology of synthetic cannabinoid SDB-006 and its regioisomeric fluorinated and methoxylated analogues

scientific article

The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons.

scientific article

The potentiating effect of calcitonin gene-related peptide on transient receptor potential vanilloid-1 activity and the electrophysiological responses of rat trigeminal neurons to nociceptive stimuli.

scientific article published on 15 February 2017

The results of an experimental indoor hydroponic Cannabis growing study, using the 'Screen of Green' (ScrOG) method-Yield, tetrahydrocannabinol (THC) and DNA analysis

scientific article published on 13 May 2010

The structure of a novel insecticidal neurotoxin, omega-atracotoxin-HV1, from the venom of an Australian funnel web spider

scientific article

The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse

scientific article

Themed section.

scientific article published in January 2015

Trigeminal ganglion neuron subtype-specific alterations of Ca(V)2.1 calcium current and excitability in a Cacna1a mouse model of migraine. ⬇️

scientific article published on 17 October 2011

What would 5-HT do? Regional diversity of 5-HT(1) receptor modulation of primary afferent neurotransmission

scientific article published on September 2012

Wide-field time-gated photoluminescence microscopy for fast ultrahigh-sensitivity imaging of photoluminescent probes.

scientific article

delta- and mu-opioid receptor mobilization of intracellular calcium in SH-SY5Y human neuroblastoma cells

scientific article

delta-Atracotoxins from australian funnel-web spiders compete with scorpion alpha-toxin binding but differentially modulate alkaloid toxin activation of voltage-gated sodium channels

scientific article published in October 1998

delta-opioid receptor-mediated actions on rostral ventromedial medulla neurons

scientific article published in January 2005

β-Arrestin-2 knockout prevents development of cellular μ-opioid receptor tolerance but does not affect opioid-withdrawal-related adaptations in single PAG neurons.

scientific article

Paulina is supported by:

About Paulina

Help