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Authors whose works are in public domain in at least one jurisdiction

List of works by Paul N Epstein

A transgenic model of acetaldehyde overproduction accelerates alcohol cardiomyopathy

scientific article

Alterations in the renal elastin-elastase system in type 1 diabetic nephropathy identified by proteomic analysis

scientific article published in March 2004

Altered response to apomorphine and haloperidol after nine days of cocaine injections ⬇️

scientific article published on February 1, 1979

Altering and analyzing glucose metabolism in perfused hearts of transgenic mice.

scientific article

Angiotensin II plays a critical role in diabetic pulmonary fibrosis most likely via activation of NADPH oxidase-mediated nitrosative damage

scientific article published on 12 April 2011

Associations between structural and functional changes to the kidney in diabetic humans and mice ⬇️

scientific article published on June 22, 2013

Beta-cell death and proliferation after intermittent hypoxia: role of oxidative stress

scientific article published on 14 December 2008

Cardiac expression of kinase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase inhibits glycolysis, promotes hypertrophy, impairs myocyte function, and reduces insulin sensitivity.

scientific article published on 25 August 2004

Cardiac mitochondrial damage and biogenesis in a chronic model of type 1 diabetes

scientific article published on 27 July 2004

Cardiac overexpression of 8-oxoguanine DNA glycosylase 1 protects mitochondrial DNA and reduces cardiac fibrosis following transaortic constriction ⬇️

scientific article published on August 26, 2011

Cardiac overexpression of alcohol dehydrogenase exacerbates cardiac contractile dysfunction, lipid peroxidation, and protein damage after chronic ethanol ingestion

scientific article published in July 2003

Cardiomyocyte defects in diabetic models and protection with cardiac-targeted transgenes.

scientific article

Cardiomyocyte dysfunction in models of type 1 and type 2 diabetes

scientific article published in January 2005

Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes

scientific article published in May 2004

Catalase transfection decreases hydrogen peroxide toxicity in a pancreatic beta cell line.

scientific article published on February 1998

Changes in the effects of cocaine during chronic treatment

scientific article published in October 1978

Chicken calmodulin promoter activity in proliferating and differentiated cells

scientific article published on 01 January 1989

Development of late-stage diabetic nephropathy in OVE26 diabetic mice

scientific article published in December 2004

Diabetes enhances acetaldehyde-induced depression of cardiac myocyte contraction

scientific article published on 01 March 2000

Diabetes induces neural degeneration in nucleus ambiguus (NA) and attenuates heart rate control in OVE26 mice.

scientific article published on 15 July 2009

Diabetic Cardiomyopathy in OVE26 Mice Shows Mitochondrial ROS Production and Divergence Between In Vivo and In Vitro Contractility

scientific article

Diabetic albuminuria is due to a small fraction of nephrons distinguished by albumin-stained tubules and glomerular adhesions.

scientific article published on 02 July 2009

Diabetic basement membrane thickening does not occur in myocardial capillaries of transgenic mice when metallothionein is overexpressed in cardiac myocytes

scientific article published on 04 February 2013

Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes

scientific article published on 08 May 2013

Elevated beta-cell calmodulin produces a unique insulin secretory defect in transgenic mice

scientific article published on 01 March 1992

Elevated hexokinase increases cardiac glycolysis in transgenic mice.

scientific article published in February 2002

Expression of yeast hexokinase in pancreatic beta cells of transgenic mice reduces blood glucose, enhances insulin secretion, and decreases diabetes ⬇️

scientific article published on December 15, 1992

Functional changes in baroreceptor afferent, central and efferent components of the baroreflex circuitry in type 1 diabetic mice (OVE26).

scientific article published on 4 December 2007

Identification of three different anti-4S RNA sera associated with autoimmune disease

scientific article published on 01 November 1982

Impaired Albumin Uptake and Processing Promote Albuminuria in OVE26 Diabetic Mice.

scientific article

Impaired baroreflex control of renal sympathetic nerve activity in type 1 diabetic mice (OVE26).

scientific article published on 19 March 2009

Inflammatory gene expression in OVE26 diabetic kidney during the development of nephropathy

scientific article published on 23 May 2011

Influence of gender on ethanol-induced ventricular myocyte contractile depression in transgenic mice with cardiac overexpression of alcohol dehydrogenase.

scientific article published in March 2003

Insulin synthesis, secretory competence, and glucose utilization are sensitized by transgenic yeast hexokinase

scientific article published on 01 June 1994

Isolation and structural analysis of the chromosomal gene for chicken calmodulin

scientific article published in January 1987

Isolation of a rat parvalbumin gene and full length cDNA.

scientific article

Long-term effect of maternal obesity on pancreatic beta cells of offspring: reduced beta cell adaptation to high glucose and high-fat diet challenges in adult female mouse offspring

scientific article published on 12 July 2005

Metallothionein alleviates cardiac contractile dysfunction induced by insulin resistance: role of Akt phosphorylation, PTB1B, PPARgamma and c-Jun.

scientific article published on 20 September 2005

Metallothionein and catalase sensitize to diabetes in nonobese diabetic mice: reactive oxygen species may have a protective role in pancreatic beta-cells

scientific article published on 01 June 2006

Metallothionein as a compensatory component prevents intermittent hypoxia-induced cardiomyopathy in mice.

scientific article published on 18 March 2014

Metallothionein over-expression in podocytes reduces adriamycin nephrotoxicity

scientific article published in February 2009

Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production

scientific article published in March 2003

Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species

scientific article published on 23 October 2003

MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity

scientific article published in May 2005

Morphology and topography of nucleus ambiguus projections to cardiac ganglia in rats and mice.

scientific article

Multiple states of U3 RNA in Novikoff hepatoma nucleoli

scientific article published on 01 November 1984

Nucleotide sequence of 7 S RNA. Homology to Alu DNA and La 4.5 S RNA.

scientific article

Overexpression of alcohol dehydrogenase exacerbates ethanol-induced contractile defect in cardiac myocytes.

scientific article published in April 2002

Overexpression of catalase provides partial protection to transgenic mouse beta cells

scientific article published on 01 October 1999

Overexpression of hexokinase protects hypoxic and diabetic cardiomyocytes by increasing ATP generation

scientific article published in January 2005

Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity

scientific article

Overexpression of metallothionein reduces diabetic cardiomyopathy.

scientific article published in January 2002

Podocyte loss in aging OVE26 diabetic mice

scientific article published on 01 January 2008

Podocyte-specific overexpression of metallothionein mitigates diabetic complications in the glomerular filtration barrier and glomerular histoarchitecture: a transmission electron microscopy stereometric analysis

scientific article published in February 2013

Podocyte-specific overexpression of the antioxidant metallothionein reduces diabetic nephropathy.

scientific article published on 16 July 2008

Potential role for Nrf2 activation in the therapeutic effect of MG132 on diabetic nephropathy in OVE26 diabetic mice

scientific article published on 6 November 2012

Primary and secondary structure of U2 snRNA.

scientific article published on November 1981

Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse

scientific article published on 01 July 1999

Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy

scientific article published in March 2006

Proteomic identification and immunolocalization of increased renal calbindin-D28k expression in OVE26 diabetic mice

scientific article published on 10 May 2005

Proteomics and diabetic nephropathy

scientific article published on 01 January 2004

Quantitative immunocytochemical study of islet cell populations in diabetic calmodulin-transgenic mice

scientific article published on 01 January 1994

Rat maternal diabetes impairs pancreatic beta-cell function in the offspring

scientific article published on 27 March 2007

Reduced cardiac fructose 2,6 bisphosphate increases hypertrophy and decreases glycolysis following aortic constriction

scientific article

Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets

scientific article published on 19 April 2006

Renal improvement by zinc in diabetic mice is associated with glucose metabolism signaling mediated by metallothionein and Akt, but not Akt2.

scientific article published on December 2013

Renal tubulointerstitial fibrosis in OVE26 type 1 diabetic mice

scientific article published on 02 December 2008

Site-specific cleavage by T1 RNase of U-1 RNA in u-1 ribonucleoprotein particles ⬇️

scientific article published on March 1, 1981

Steroidogenic acute regulatory-related lipid transfer domain protein 5 localization and regulation in renal tubules

scientific article

Structure and ultrastructure of the endocrine pancreas in diabetic transgenic mice

scientific article published in January 1996

Suppression of doxorubicin cardiotoxicity by overexpression of catalase in the heart of transgenic mice

scientific article published on 01 May 1996

TEM stereometric analyses of glomeruli in aging OVE26 transgenic diabetic mice

scientific article published on 10 June 2011

Targeted overexpression of an inactive calmodulin that binds Ca2+ to the mouse pancreatic beta-cell results in impaired secretion and chronic hyperglycemia

scientific article published in January 1995

The nucleotide sequence of nuclear U6 (4.7 S) RNA.

scientific article published in September 1980

The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta cells.

scientific article published on 04 September 2008

Therapeutic effect of MG-132 on diabetic cardiomyopathy is associated with its suppression of proteasomal activities: roles of Nrf2 and NF-κB.

scientific article published on 7 December 2012

Thermoregulatory and heat-shock protein response deficits in cold-exposed diabetic mice

scientific article published on 01 March 1996

Transgenic expression of insulin-response element binding protein-1 in beta-cells reproduces type 2 diabetes

scientific article published on 12 February 2009

Transgenic overexpression of aldehyde dehydrogenase-2 rescues chronic alcohol intake-induced myocardial hypertrophy and contractile dysfunction.

scientific article published on 30 March 2009

Ultrastructural and functional analyses of nephropathy in calmodulin-induced diabetic transgenic mice

scientific article published in January 1997

Ultrastructural morphometry of capillary basement membrane thickness in normal and transgenic diabetic mice

scientific article published in April 2003

Unequal potency of transgenic yeast hexokinase on pancreatic beta cell metabolism and secretion

scientific article published on 01 May 1996

Uninephrectomy of diabetic OVE26 mice greatly accelerates albuminuria, fibrosis, inflammatory cell infiltration and changes in gene expression

scientific article published on 09 June 2011

Zinc rescue of Akt2 gene deletion-linked murine cardiac dysfunction and pathological changes is metallothionein-dependent

scientific article

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