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List of works by Markus Bachschmid

A new "sunshine" in the vasculature?

scientific article published in April 2005

A new pitfall in detecting biological end products of nitric oxide-nitration, nitros(yl)ation and nitrite/nitrate artefacts during freezing.

scientific article published in August 2003

A redox-resistant sirtuin-1 mutant protects against hepatic metabolic and oxidant stress.

scientific article published on 22 January 2014

Aberrant Caspase Activation in Laminin-α2-Deficient Human Myogenic Cells is Mediated by p53 and Sirtuin Activity.

scientific article

Acetaminophen inhibits prostanoid synthesis by scavenging the PGHS-activator peroxynitrite

scientific article published on 27 August 2007

Age-associated cellular relocation of Sod 1 as a self-defense is a futile mechanism to prevent vascular aging

scientific article published on 19 April 2006

Age-related changes of vitamin A status

scientific article published on 01 January 2004

Attenuated cardiovascular hypertrophy and oxidant generation in response to angiotensin II infusion in glutaredoxin-1 knockout mice.

scientific article

Autocatalytic nitration of prostaglandin endoperoxide synthase-2 by nitrite inhibits prostanoid formation in rat alveolar macrophages

scientific article

COX-2 inhibitors selectively block prostacyclin synthesis in endotoxin-exposed vascular smooth muscle cells

scientific article published on 20 February 2004

Cardiovascular aging is associated with vitamin E increase

scientific article

Chemical model systems for cellular nitros(yl)ation reactions

scientific article

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

scientific article published on 26 October 2017

Decreased ATP production and myocardial contractile reserve in metabolic heart disease.

scientific article published on 31 January 2018

Decreased plasma and tissue levels of vitamin C in a rat model of aging: implications for antioxidative defense

scientific article published in April 2003

Deletion of p66shc gene protects against age-related endothelial dysfunction

scientific article published on 25 October 2004

Direct detection of S-palmitoylation by mass spectrometry

scientific article published on 6 December 2013

Does reversible cysteine oxidation link the Western diet to cardiac dysfunction?

scientific article

Ebselen as a peroxynitrite scavenger in vitro and ex vivo

scientific article published on 01 January 2000

Endogenous peroxynitrite modulates PGHS-1-dependent thromboxane A2 formation and aggregation in human platelets

scientific article published on 15 May 2008

Endomembrane H-Ras controls vascular endothelial growth factor-induced nitric-oxide synthase-mediated endothelial cell migration

scientific article published on 2 April 2013

Endothelial Cell Redox Regulation of Ischemic Angiogenesis.

scientific article published on 26 February 2016

Endothelial cell activation by endotoxin involves superoxide/NO-mediated nitration of prostacyclin synthase and thromboxane receptor stimulation

scientific article published on 28 March 2003

Endothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice

scientific article published on 26 October 2019

Endotoxin elicits nitric oxide release in rat but prostacyclin synthesis in human and bovine vascular smooth muscle cells

scientific article published in February 2005

Energetic Dysfunction Is Mediated by Mitochondrial Reactive Oxygen Species and Precedes Structural Remodeling in Metabolic Heart Disease

scientific article published on 25 June 2019

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

scientific article published on 18 May 2017

Expression and activity patterns of nitric oxide synthases and antioxidant enzymes reveal a substantial heterogeneity between cardiac and vascular aging in the rat.

scientific article published in January 2005

Genetic deletion of p66(Shc) adaptor protein prevents hyperglycemia-induced endothelial dysfunction and oxidative stress.

scholarly article

Genetically targeted fluorescent probes reveal dynamic calcium responses to adrenergic signaling in multiple cardiomyocyte compartments

scientific article published on 09 July 2019

Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1.

scientific article published on 13 December 2016

Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization

scientific article published on 30 January 2014

Glutathione adducts induced by ischemia and deletion of glutaredoxin-1 stabilize HIF-1α and improve limb revascularization.

scientific article published on 09 May 2016

Glutathione peroxidase-1 deficiency potentiates dysregulatory modifications of endothelial nitric oxide synthase and vascular dysfunction in aging.

scientific article

Glutathionylation of the Active Site Cysteines of Peroxiredoxin 2 and Recycling by Glutaredoxin

scientific article published on 24 November 2015

High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II.

scientific article

High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species

scientific article published in February 2003

High-fat diet increases and the polyphenol, S17834, decreases acetylation of the sirtuin-1-dependent lysine-382 on p53 and apoptotic signaling in atherosclerotic lesion-prone aortic endothelium of normal mice

scientific article

Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure

scientific article

Improved mass spectrometry-based activity assay reveals oxidative and metabolic stress as sirtuin-1 regulators

scientific article published on 05 March 2019

MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits

scientific article published on 01 August 2018

Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease

scientific article published on 11 January 2016

Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells.

scientific article published on 2 August 2011

Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins.

scientific article published on 7 December 2015

Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis

scientific article

Oxidative stress and mitochondrial aldehyde dehydrogenase activity: a comparison of pentaerythritol tetranitrate with other organic nitrates

scientific article

Oxidative stress-associated vascular aging is independent of the protein kinase C/NAD(P)H oxidase pathway

scientific article published in March 2004

Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge.

scientific article published on 31 December 2015

Peroxynitrite provides the peroxide tone for PGHS-2-dependent prostacyclin synthesis in vascular smooth muscle cells

scientific article published on 5 May 2005

Production of adeno-associated virus vectors for in vitro and in vivo applications

scientific article published on 19 September 2019

Protein tyrosine nitration and thiol oxidation by peroxynitrite-strategies to prevent these oxidative modifications

scientific article published on 8 April 2013

Redox Regulation via Glutaredoxin-1 and Protein S-Glutathionylation

scientific article published on 23 January 2020

Redox regulation of sirtuin-1 by S-glutathiolation.

scientific article

Redox regulation of vascular prostanoid synthesis by the nitric oxide-superoxide system.

scientific article

Redox regulation: a new challenge for pharmacology

scientific article published in September 2005

Reducing protein oxidation reverses lung fibrosis

scientific article published on 09 July 2018

Regulation of cell physiology and pathology by protein S-glutathionylation: lessons learned from the cardiovascular system.

scientific article published on March 2012

Regulation of neovascularization by S-glutathionylation via the Wnt5a/sFlt-1 pathway.

scientific article published on December 2014

Role for peroxynitrite in the inhibition of prostacyclin synthase in nitrate tolerance

scientific article

S- to N-Palmitoyl Transfer During Proteomic Sample Preparation

scientific article published on 4 January 2016

S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein

scientific article published on 24 August 2006

Selective inhibition of prostacyclin synthase activity by rofecoxib

scientific article published on March 2007

Signalling processes in endothelial ageing in relation to chronic oxidative stress and their potential therapeutic implications in humans

scientific article published on 7 November 2008

Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.

scientific article published on 13 February 2017

Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction

scientific article published on 30 January 2017

Specific nitration at tyrosine 430 revealed by high resolution mass spectrometry as basis for redox regulation of bovine prostacyclin synthase.

scientific article

Superoxide as a messenger of endothelial function.

scientific article

Surfactant-Induced Artifacts during Proteomic Sample Preparation

scientific article published on 20 May 2015

The impact of metal catalysis on protein tyrosine nitration by peroxynitrite

scientific article published in May 2004

The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells.

scientific article published on 11 September 2016

Unlocking the Secrets of Mitochondria in the Cardiovascular System: Path to a Cure in Heart Failure—A Report from the 2018 National Heart, Lung, and Blood Institute Workshop

scientific article published on 01 October 2019

Upregulation of Glutaredoxin-1 Activates Microglia and Promotes Neurodegeneration: Implications for Parkinson's Disease

scientific article published on 25 May 2016

Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension

scientific article

Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness.

scientific article published on 18 July 2016

c-Jun N-terminal kinase 2 deficiency protects against hypercholesterolemia-induced endothelial dysfunction and oxidative stress

scientific article

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