Search filters

List of works by Ken-ichi Yamada

A disruption mechanism of the molecular clock in a MPTP mouse model of Parkinson's disease.

scientific article

A novel DPP-4 inhibitor teneligliptin scavenges hydroxyl radicals: In vitro study evaluated by electron spin resonance spectroscopy and in vivo study using DPP-4 deficient rats

scientific article published on 2 November 2015

A novel ascorbic acid-resistant nitroxide in fat emulsion is an efficient brain imaging probe for in vivo EPR imaging of mouse.

scientific article published on 26 September 2011

Acyl-protected hydroxylamines as spin label generators for EPR brain imaging.

scientific article

Advantageous application of a surface coil to EPR irradiation in overhauser-enhanced MRI.

scientific article published in April 2007

Analysis of nitroxyl spin probes in mouse brain by X-band ESR with microdialysis technique.

scientific article

Are free radical reactions increased in the diabetic eye?

scientific article published on 01 March 2007

Ascorbic acid reverses the prolonged anesthetic action of pentobarbital in Akr1a-knockout mice

scientific article

Brain contrasting ability of blood-brain-barrier-permeable nitroxyl contrast agents for magnetic resonance redox imaging

scientific article published on 28 September 2015

Brain imaging in methamphetamine-treated mice using a nitroxide contrast agent for EPR imaging of the redox status and a gadolinium contrast agent for MRI observation of blood-brain barrier function

scientific article

Brain redox imaging in the pentylenetetrazole (PTZ)-induced kindling model of epilepsy by using in vivo electron paramagnetic resonance and a nitroxide imaging probe

scientific article

Determination of reactive oxygen species associated with the degeneration of dopaminergic neurons during dopamine metabolism.

scientific article published in March 2010

Development of novel nitroxyl radicals for controlling reactivity with ascorbic acid

scientific article published in June 2009

Differential protection by nitroxides and hydroxylamines to radiation-induced and metal ion-catalyzed oxidative damage.

scientific article published on November 2002

Dynamic nuclear polarization properties of nitroxyl radicals used in Overhauser-enhanced MRI for simultaneous molecular imaging

scientific article published on 27 July 2006

Dynamic nuclear polarization studies of redox-sensitive nitroxyl spin probes in liposomal solution

scientific article

Enhanced intraarticular free radical reactions in adjuvant arthritis rats

scientific article published in May 2006

Evaluation and comparison of pulsed and continuous wave radiofrequency electron paramagnetic resonance techniques for in vivo detection and imaging of free radicals

scientific article published on 01 February 2002

Factors influencing nitroxide reduction and cytotoxicity in vitro.

scientific article published on June 2004

Fluorescence probe for the convenient and sensitive detection of ascorbic acid

scientific article

Fluorescence probes to detect lipid-derived radicals

scientific article published on 13 June 2016

Formation of TEMPOL-hydroxylamine during reaction between TEMPOL and hydroxyl radical: HPLC/ECD study

scientific article published in May 2008

Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a).

scientific article published on 22 November 2016

High-fat diet-induced obesity and insulin resistance were ameliorated via enhanced fecal bile acid excretion in tumor necrosis factor-alpha receptor knockout mice

scientific article published on 18 August 2011

In vivo EPR spectroscopic imaging for a liposomal drug delivery system

scientific article published in May 2005

In vivo detection of free radicals induced by diethylnitrosamine in rat liver tissue

scientific article published on 20 February 2006

In vivo evaluation of novel nitroxyl radicals with reduction stability.

scientific article published on 7 September 2010

In vivo imaging of mitochondrial function in methamphetamine-treated rats

scientific article published on 23 May 2011

In vivo measurement of redox status in streptozotocin-induced diabetic rat using targeted nitroxyl probes

scientific article

Inhibition of myeloperoxidase- and neutrophil-mediated oxidant production by tetraethyl and tetramethyl nitroxides

scientific article published on 22 February 2014

Involvement of nitric oxide with activation of Toll-like receptor 4 signaling in mice with dextran sodium sulfate-induced colitis.

scientific article published on 30 June 2014

Kidney fibrosis is independent of the amount of ascorbic acid in mice with unilateral ureteral obstruction

scientific article published on 21 July 2014

Lipid radicals cause light-induced retinal degeneration

scientific article published on 20 September 2017

Lipophilic triphenylphosphonium derivatives enhance radiation-induced cell killing via inhibition of mitochondrial energy metabolism in tumor cells.

scientific article published on 13 January 2017

Membrane permeabilization mechanisms of a cyclic antimicrobial peptide, tachyplesin I, and its linear analog

scientific article published on 01 August 1997

Monitoring the aggregation processes of amyloid-β using a spin-labeled, fluorescent nitroxyl radical.

scientific article published on 25 March 2011

Nifedipine treatment reduces brain damage after transient focal ischemia, possibly through its antioxidative effects

scientific article published on 12 May 2011

Nitroxides prevent exacerbation of indomethacin-induced gastric damage in adjuvant arthritis rats

scientific article published on 18 August 2011

Non-invasive imaging of the levels and effects of glutathione on the redox status of mouse brain using electron paramagnetic resonance imaging

scientific article

Noninvasive assessment of the brain redox status after transient middle cerebral artery occlusion using Overhauser-enhanced magnetic resonance imaging.

scientific article published on 24 June 2009

Noninvasive in vivo oximetric imaging by radiofrequency FT EPR

scientific article published on 01 May 2002

Noninvasive mapping of reactive oxygen species by in vivo electron spin resonance spectroscopy in indomethacin-induced gastric ulcers in rats

scientific article

Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress

scientific article

Overhauser-enhanced magnetic resonance imaging characterization of mitochondria functional changes in the 6-hydroxydopamine rat model.

scientific article published on 17 August 2011

Oxygen concentration dependence of lipid peroxidation and lipid-derived radical generation: application of profluorescent nitroxide switch

scientific article published on 07 July 2011

Pharmacokinetics of a triarylmethyl-type paramagnetic spin probe used in EPR oximetry

scientific article published on 01 October 2004

Photodecomposition of tetrabromobisphenol A in aqueous humic acid suspension by irradiation with light of various wavelengths

scientific article published on 5 January 2016

Rapid and convenient detection of ascorbic acid using a fluorescent nitroxide switch

scientific article published on 28 September 2012

Reductive detoxification of acrolein as a potential role for aldehyde reductase (AKR1A) in mammals.

scientific article

Separable detection of lipophilic- and hydrophilic-phase free radicals from the ESR spectrum of nitroxyl radical in transient MCAO mice.

scientific article published on 20 July 2009

Simultaneous molecular imaging of redox reactions monitored by Overhauser-enhanced MRI with 14N- and 15N-labeled nitroxyl radicals.

scientific article

Single-point (constant-time) imaging in radiofrequency Fourier transform electron paramagnetic resonance

scientific article published on 01 August 2002

Spatially resolved time-course studies of free radical reactions with an EPRI/MRI fusion technique

scientific article published in October 2006

Structural concept of nitroxide as a lipid peroxidation inhibitor

scientific article published on 18 April 2011

Structure-reactivity relationship of piperidine nitroxide: electrochemical, ESR and computational studies

scientific article published on 29 December 2010

TEMPOL increases NAD(+) and improves redox imbalance in obese mice.

scientific article published on 26 February 2016

Tempol intake improves inflammatory status in aged mice

scientific article

The detrimental effect of nitric oxide on tissue is associated with inflammatory events in the vascular endothelium and neutrophils in mice with dextran sodium sulfate-induced colitis

scientific article published on 09 October 2012

Whole-body kinetic image of a redox probe in mice using Overhauser-enhanced MRI.

scientific article published on 30 April 2012