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List of works by David A. Brenner

15th International Symposium on Cells of the Hepatic Sinusoid, 2010.

scientific article

208 Deletion of PPARy in Hepatic Stellate Cells Attenuates Regression of Liver Fibrosis

226 The Mechanism of Hepatic Stellate Cell Inactivation During Reversal of Liver Fibrosis

297 Deletion of Fibrocytes in Mice Attenuates Experimental Liver Fibrosis

5' stem-loop of collagen alpha 1(I) mRNA inhibits translation in vitro but is required for triple helical collagen synthesis in vivo.

scientific article

903 Novel Association Between Serum Pentraxin-2 Levels and Advanced Fibrosis in Well-Characterized Patients With NAFLD

A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations

scientific article published in November 2004

A fluorometric assay for measurement of protoporphyrinogen oxidase activity in mammalian tissue

scientific article published on 01 January 1980

A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches

scientific article

A simplified method for the preparation of transcriptionally active liver nuclear extracts

scientific article

Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression

scientific article

Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes

scientific article published on 17 November 2015

Aging and liver disease

scientific article

Aging increases the susceptibility of hepatic inflammation, liver fibrosis and aging in response to high-fat diet in mice

scientific article published on 30 August 2016

Akt activation protects rat liver from ischemia/reperfusion injury

scientific article published in October 2004

Alcohol causes both tolerance and sensitization of rat Kupffer cells via mechanisms dependent on endotoxin

scientific article published in August 1998

Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium

scientific article published on 27 May 2008

Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis

scientific article published in November 2007

Alteration of interferon-α/β receptors in chronic hepatitis B patients

scientific article published on 29 March 2011

An exon 10 deletion in the mouse ferrochelatase gene has a dominant-negative effect and causes mild protoporphyria

scientific journal article

Analysis of signaling protein kinases in human colon or colorectal carcinomas

scientific article

Anandamide induces necrosis in primary hepatic stellate cells

scientific article

Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice

scientific article published on September 2009

Anti-fibrogenic strategies and the regression of fibrosis

scientific article published on April 2011

Antiapoptotic effect of c-Jun N-terminal Kinase-1 through Mcl-1 stabilization in TNF-induced hepatocyte apoptosis

scientific article published on 6 January 2009

Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats

scientific journal article

Association between serum interleukin-6 concentrations and mortality in older adults: the Rancho Bernardo study

scientific article

Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice

scientific article published in August 2005

Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease

scientific article

Binding of upstream stimulatory factor to an E-box in the 3'-flanking region stimulates alpha1(I) collagen gene transcription.

scientific article published on January 1997

Bone Morphogenetic Protein 7 is Elevated in Patients with Chronic Liver Disease and Exerts Fibrogenic Effects on Human Hepatic Stellate Cells

article

Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis

scientific article published on 9 June 2006

Bradykinin attenuates hepatocellular damage and fibrosis in rats with chronic liver injury

scientific article published on 26 September 2007

CCR2 promotes hepatic fibrosis in mice

scientific article published on July 2009

CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice

scientific article

Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in rats.

scientific article published on 6 February 2009

Ceramide activates the stress-activated protein kinases

scientific article published on 01 September 1995

Clinical syndromes of alcoholic liver disease

scientific article

Cloning of murine ferrochelatase ⬇️

scientific article published on February 1, 1991

Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice

scientific article

Comment on "Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice"

scientific article published on 01 January 2016

Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice

scientific article published on 01 May 1998

Contribution of Fibrocytes to Liver Fibrosis: Current Concept and Future Prospect

Corn oil rapidly activates nuclear factor-kappaB in hepatic Kupffer cells by oxidant-dependent mechanisms.

scientific article published in November 1999

Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD

scientific article

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

scientific article

DNase I-hypersensitive sites enhance alpha1(I) collagen gene expression in hepatic stellate cells

scientific article published in February 2003

Data from arrays: an embarrassment of riches

scientific article

Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation

scientific article published on 29 July 2015

Delivery of matrix metalloproteinase-1 attenuates established liver fibrosis in the rat.

scientific article

Development of a new, simple rat model of early alcohol-induced liver injury based on sensitization of Kupffer cells

scientific article published on 01 June 1999

Diagnosis and management of patients with α1-antitrypsin (A1AT) deficiency

scientific article

Different mechanisms decrease hepatic collagen and albumin production in fasted rats

scientific article published in September 1988

Differential expression of human lysyl hydroxylase genes, lysine hydroxylation, and cross-linking of type I collagen during osteoblastic differentiation in vitro

scientific article published on 01 August 1999

Differential expression of the transfected liver-specific alpha 1-inhibitor III gene in normal hepatocytes and hepatoma cells in culture

scientific article published in February 1992

Direct hepatotoxic effect of KC chemokine in the liver without infiltration of neutrophils

scientific article published in September 2005

Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis

scientific article

Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial

scientific article

Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C

scientific article published on 23 July 2009

Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response

scholarly article

Enteric dysbiosis associated with a mouse model of alcoholic liver disease

scientific article

Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB.

scientific article published on 25 September 2007

Evidence for a common progenitor of epithelial and mesenchymal components of the liver.

scientific article

Expression of human immunodeficiency virus-1 in human colonic cells.

scientific article published in January 1991

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury.

scientific article published on January 2005

Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells

scientific article published on 01 September 1996

Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial)

scientific article

Ferrochelatase cDNA delivered by adenoviral vector corrects biochemical defect in protoporphyric cells

scientific article published on 01 October 1995

Fibroblast growth factor inducible 14 as potential target in patients with alcoholic hepatitis

scientific article

Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver

scientific article

Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection

scientific article

Fibrogenesis of parenchymal organs

scientific article published on April 2008

Fra, Fra away: the complex role of activator protein 1 in liver injury

scientific article

Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis

scientific article published on 11 April 2005

From quiescence to activation: Gene regulation in hepatic stellate cells

scientific article published on 01 October 2004

GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis

scientific article

Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus.

scientific article published on 16 October 2017

Gastric bypass surgery improves metabolic and hepatic abnormalities associated with nonalcoholic fatty liver disease

scientific article published on 01 May 2006

Gastrointestinal basic science 2002-2003: the year in review

scientific article published on January 2004

Gene delivery of Cu/Zn-superoxide dismutase improves graft function after transplantation of fatty livers in the rat.

scientific article

Gene expression profiles during hepatic stellate cell activation in culture and in vivo

scientific article published on 21 February 2007

Genetic covariance between gamma-glutamyl transpeptidase and fatty liver risk factors: role of beta2-adrenergic receptor genetic variation in twins

scientific article

Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice

scientific article published on 20 June 2010

Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal

scientific article

Genomics of liver fibrosis and cirrhosis

scientific article published on February 2007

Gliotoxin-mediated apoptosis of activated human hepatic stellate cells

scientific article

Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease

scientific article published on May 2017

Heme content of normal and porphyric cultured skin fibroblasts

scientific article published in December 1977

Hepatic porphyrias.

scientific article

Hepatic stellate cells and the reversal of fibrosis

scientific article published on October 2006

Hepatic stellate cells primed with cytokines upregulate inflammation in response to peptidoglycan or lipoteichoic acid

scientific article published on 17 April 2006

Hepatic stellate cells secrete angiopoietin 1 that induces angiogenesis in liver fibrosis.

scientific article published on 3 August 2008

Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells

scientific article published on February 2004

Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity

scientific article

Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells

scientific article

Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice

scientific article

Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study

scientific article

High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase

scientific article published on February 2008

Human hepatic stellate cell isolation and characterization.

scientific article published in November 2017

Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration

scientific article

Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing

scientific article

Identification of small molecule activators of cryptochrome

scientific article

Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood

scientific article

Immunosuppression, hepatitis B virus variants: Synergistic role in hepatic fibrogenesis

scientific article published in September 2006

In vivo activation of mitogen-activated protein kinases in rat intestinal neoplasia

scientific article published on 01 November 1997

Inactivation of myofibroblasts during regression of liver fibrosis

scientific article published on 16 January 2013

Increased Risk of Death, in the Hospital and Outside the Intensive Care Unit, for Patients With Cirrhosis After Cardiac Arrest

scientific article

Increased expression of collagenase in the liver induces hepatocyte proliferation with cytoplasmic accumulation of beta-catenin in the rat.

scientific article published in April 2003

Infiltration of circulating myeloid cells through CD95L contributes to neurodegeneration in mice

scientific article

Inflammatory dysregulation of blood monocytes in Parkinson's disease patients

scientific article

Information assimilation and distribution challenges and goals for real and virtual journals

scientific article

Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction

scientific article

Inhibition of NFκB in activated rat hepatic stellate cells by proteasome inhibitors and an IκB super-repressor ⬇️

scientific article published on May 1, 1998

Inhibition of collagen alpha 1(I) expression by the 5' stem-loop as a molecular decoy

scientific article published on 11 March 2002

Inhibition of nuclear factor kappaB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor alpha in mice

scientific article

Inhibition of transforming growth factor-beta/Smad signaling improves regeneration of small-for-size rat liver grafts

scientific article

Innate immunity in alcoholic liver disease

scientific article published on 20 January 2011

Interactions between the intestinal microbiome and liver diseases

scientific article published on 15 January 2014

Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice

scientific article

Interleukin-6 increases rat metalloproteinase-13 gene expression through stimulation of activator protein 1 transcription factor in cultured fibroblasts

scientific article published on 01 October 1999

Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

scientific article

Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation

scientific article published in February 2016

Introducing PNAS Nexus

Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments.

scientific article published on 10 August 2009

Is it the end of the line for the EMT?

scientific article published on 01 May 2011

JNK mediates hepatic ischemia reperfusion injury

scientific article

Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells

scientific article published in August 2002

Lipopolysaccharide-binding protein modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation

scientific article published on 13 April 2006

List of Contributors

Liver carcinogenesis: rodent models of hepatocarcinoma and cholangiocarcinoma

scientific article

Liver fibrogenesis: a new role for the renin-angiotensin system

scientific article

Liver fibrosis

scientific article (publication date: February 2005)

Liver inflammation and fibrosis

scientific article published on 3 January 2017

Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply

scientific article published in July 2006

Liver: DNA methylation controls liver fibrogenesis

scientific article published on 10 February 2016

Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis

scientific article published on 01 August 2006

M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway

scientific article

MELD and the practicing gastroenterologist

scientific article published on 01 October 2003

Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease

scientific article

Magnetic resonance elastography identifies fibrosis in adults with alpha-1 antitrypsin deficiency liver disease: a prospective study

scientific article

Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study

scientific article

Matrix metalloproteinase gene delivery for liver fibrosis

scientific article published on 19 June 2007

Mechanisms of Liver Injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways

scientific article

Mechanisms of alcohol-induced hepatic fibrosis: a summary of the Ron Thurman Symposium

scientific article

Mechanisms of fibrogenesis

scientific article published on February 2008

Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.

scientific article published on 13 March 2017

Migration of fibrocytes in fibrogenic liver injury

scientific article

Minimizing oxidative stress by gene delivery of superoxide dismutase accelerates regeneration after transplantation of reduced-size livers in the rat.

scientific article published in April 2006

Mitogens and hepatocyte growth control in vivo and in vitro.

scientific article published in November 1990

Mo1005 Effect of Weight Loss on Novel MRI Quantitative Changes in Liver and Pancreatic Fat in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease

Mo1542 Effect of Weight Loss on MRE Estimated Stiffness in Patients With Nonalcoholic Fatty Liver Disease

Moderate alcohol drinking: effects on the heart and liver

scientific article published on 01 November 2000

Molecular mechanisms of alcohol-induced hepatic fibrosis

scientific article

Molecular pathogenesis of alcohol-induced hepatic fibrosis

scientific article

Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow.

scientific article

Mutation of the 5'-untranslated region stem-loop structure inhibits α1(I) collagen expression in vivo

scientific article

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

scientific article

NADPH oxidase in the liver: defensive, offensive, or fibrogenic?

scientific article published on July 2006

NADPH oxidase mediated oxidative stress in hepatic fibrogenesis

scientific article published in December 2011

NEK1 mutations in familial amyotrophic lateral sclerosis

scientific article published on 5 March 2016

NF-I/Sp1 switch elements regulate collagen alpha 1(I) gene expression

scientific article

NF-kappaB activation in Kupffer cells after partial hepatectomy

scientific article published on 19 May 2005

NF-kappaB inhibits expression of the alpha1(I) collagen gene.

scientific article published on October 1999

NF-κB

NK and NKT cells in liver injury and fibrosis

scientific article published on 26 September 2008

NOX in liver fibrosis

scientific article published on 2 May 2007

New Approaches for Studying Alcoholic Liver Disease

scientific article published on 14 September 2014

New Developments on the Treatment of Liver Fibrosis

scientific article published on 22 June 2016

New functions for the aryl hydrocarbon receptor

scientific article published on 01 February 1996

New therapies for hepatic fibrosis

scientific article published on 20 July 2015

Next-generation academic medicine ⬇️

scientific article published on November 1, 2012

Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent

scientific article

Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase

scientific article published on July 2011

Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis

scientific article published on 19 June 2017

Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells.

scientific article

Novel 3D Magnetic Resonance Elastography for the Noninvasive Diagnosis of Advanced Fibrosis in NAFLD: A Prospective Study.

scientific article

Novel association between serum pentraxin-2 levels and advanced fibrosis in well-characterised patients with non-alcoholic fatty liver disease

scientific article published on 29 June 2015

Novel perspectives on the origins of the hepatic myofibroblasts

Novel perspectives on the origins of the hepatic myofibroblasts

Nuclear factor kappaB in proliferation, activation, and apoptosis in rat hepatic stellate cells

scientific article published on 01 July 2000

Nuclear factor-kappaB in the liver: friend or foe?

scientific article published on 01 June 2007

Obesity and alcohol synergize to increase the risk of incident hepatocellular carcinoma in men.

scientific article published on 17 August 2010

Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases

scientific article published on June 1994

Origin of myofibroblasts in liver fibrosis

scientific article published on 06 June 2012

Origin of myofibroblasts in the fibrotic liver in mice

scientific article

Overexpression of endoglin modulates TGF-β1-signalling pathways in a novel immortalized mouse hepatic stellate cell line

scientific article

Oxidative stress in alcoholic liver disease: role of NADPH oxidase complex

scientific article published on March 2008

Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

scientific article

Porphyrias

scientific article published on 01 October 1998

Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism

scientific article published on June 2004

Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver

scientific article published on 28 May 2003

Promising Therapy Candidates for Liver Fibrosis

scientific article

Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist

scientific article

Protective effect of human serum amyloid P on CCl4-induced acute liver injury in mice

scientific article published on 14 June 2017

Publisher Correction: Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus

scientific article published on 12 December 2017

Recent advancement of molecular mechanisms of liver fibrosis

scientific article published on 13 April 2015

Recent advances in liver stem cell therapy

scientific article published in July 2010

Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells

scientific article

Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats

Regulation of alpha1(I) collagen messenger RNA decay by interactions with alphaCP at the 3'-untranslated region

scientific article published on 17 February 2004

Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype

scientific article

Report of the American Gastroenterological Association (AGA) Institute Obesity Task Force

scientific article published on 01 May 2007

Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis

scientific article

Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts

scientific article published on September 2013

Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis

scientific article published on October 2010

Role of Gut Microbiota in Liver Disease

scientific article

Role of NADPH oxidases in liver fibrosis

scientific article

Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes

scientific article published on 01 July 2002

Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis

scientific article published on June 2007

Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease

scientific article published on January 2010

Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alpha

scientific article

Roles of AKT and sphingosine kinase in the antiapoptotic effects of bile duct ligation in mouse liver

scientific article published in December 2005

Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition

scientific article (publication date: May 2003)

Semaphorin 7A contributes to TGF-β-mediated liver fibrogenesis.

scientific article published on 11 July 2013

Serum levels of alanine aminotransferase decrease with age in longitudinal analysis

scientific article published on 20 October 2011

Serum γ-glutamyltranspeptidase predicts all-cause, cardiovascular and liver mortality in older adults

scientific article published on March 2013

Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study ⬇️

scientific article published on 17 June 2016

Signal transduction during liver regeneration

scientific article

Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial

scientific article

Sp1 binding activity increases in activated Ito cells

scientific article published on 01 July 1995

Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models

scientific article

Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition

Synergism between obesity and alcohol in increasing the risk of hepatocellular carcinoma: a prospective cohort study

scientific article published on 24 January 2013

Synergistic effects of family history of hepatocellular carcinoma and hepatitis B virus infection on risk for incident hepatocellular carcinoma.

scientific article

Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct-ligated rats

scientific article published on 01 May 2005

Systemic mediators induce fibrogenic effects in normal liver after partial bile duct ligation

scientific article published on 01 November 2006

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis

scientific article

TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells ⬇️

scientific article published on November 1, 2001

TLR4 enhances TGF-beta signaling and hepatic fibrosis

scientific article (publication date: November 2007)

TNF alpha-induced hepatocyte apoptosis is associated with alterations of the cell cycle and decreased stem loop binding protein

scientific article

TNFalpha is required for cholestasis-induced liver fibrosis in the mouse

scientific article published on 6 November 2008

TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis

scientific article

Targeted disruption of the mouse ferrochelatase gene producing an exon 10 deletion

scientific journal article

The Characteristics of Myofibroblasts in Various Cholestatic Liver Injury Models in Mice

The Mitochondrial Permeability Transition Augments Fas-induced Apoptosis in Mouse Hepatocytes

scientific article published in Journal of Biological Chemistry

The Role of Human CYP2E1 in Liver Fibrosis

The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts

scientific article

The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis

scientific article

The enteropathy of prostaglandin deficiency

scientific article published on 16 January 2009

The enzymatic defect in variegate prophyria. Studies with human cultured skin fibroblasts

scientific article published on 01 April 1980

The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells

scientific article

The future of gastroenterology and gastroenterology

scientific article published on 01 May 2006

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

scientific article

The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice

scientific article

The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis

scientific article

The role of IL-17 signaling in regulation of the liver-brain axis and intestinal permeability in Alcoholic Liver Disease

scientific article published on 19 February 2016

The role of NF-kappaB in hepatocarcinogenesis: promoter or suppressor?

scientific article

The role of TGFbeta1 in initiating hepatic stellate cell activation in vivo

scientific article published in January 1999

The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression

scientific article published on 26 December 2002

The role of human cytochrome P450 2E1 in liver inflammation and fibrosis.

scientific article published on 30 October 2017

The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation

scientific article

Three distinct cell populations express extracellular matrix proteins and increase in number during skeletal muscle fibrosis

scientific article

Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

scientific article published on February 2013

Toll-like receptor 2-mediated intestinal injury and enteric tumor necrosis factor receptor I contribute to liver fibrosis in mice

scientific article published on 27 July 2012

Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice

scientific article published on 4 April 2011

Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells

scientific article published on 01 May 2003

Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice

scientific article

Toll-like receptor signaling in the liver

scientific article

Toll-like receptors and adaptor molecules in liver disease: update

scientific article published on July 2008

Transcriptional repression of the transforming growth factor β (TGF-β) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor κB (NF-κB) p50 enhances TGF-β signaling in hepatic stellate cells

scientific article published on 21 January 2014

Transforming growth factor-alpha stimulates proto-oncogene c-jun expression and a mitogenic program in primary cultures of adult rat hepatocytes

scientific article published in May 1989

Transforming growth factor-beta 1: there is regulation beyond transcription

scientific article published on 01 January 1993

Transient induction of c-jun during hepatic regeneration

scientific article published in June 1990

Tu1028 Correlation Between Liver Histology and Novel Magnetic Resonance Imaging in Adult Patients With Nonalcoholic Fatty Liver Disease

Tu1697 Mesothelin Signaling Regulates Proliferation of Portal Fibroblasts and Contributes to the Pathogenesis of Cholestatic Liver Fibrosis in Mice

Tumor necrosis factor alpha prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: role of nuclear factor-kappaB

scientific article published on 01 December 2000

Tumor necrosis factor alpha-induced interleukin-8 production via NF-kappaB and phosphatidylinositol 3-kinase/Akt pathways inhibits cell apoptosis in human hepatocytes

scientific article published on November 2002

Up-regulated eotaxin plasma levels in chronic liver disease patients indicate hepatic inflammation, advanced fibrosis and adverse clinical course

scientific article published on 01 August 2007

Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials

scientific article published on 17 October 2013

Weight Loss Decreases Magnetic Resonance Elastography Estimated Liver Stiffness in Nonalcoholic Fatty Liver Disease

scientific article published on 3 October 2016

Western Diet Accelerates NASH in foz / foz Mouse

What goes up must come down: the emerging role of microRNA in fibrosis.

scientific article

What is the potential role of antifibrotic agents for the treatment of liver disease?

scientific article published on 15 July 2008

What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis

scientific article

Zinc finger protein 267 is up-regulated during the activation process of human hepatic stellate cells and functions as a negative transcriptional regulator of MMP-10

scientific article

c-Jun N-terminal kinase mediates hepatic injury after rat liver transplantation

scientific article

c-Jun N-terminal kinase signaling in the pathogenesis of nonalcoholic fatty liver disease: Multiple roles in multiple steps.

scientific article

c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice

scientific article published on 21 June 2009

c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration

scientific article published in April 2003

p18(INK4c) collaborates with other CDK-inhibitory proteins in the regenerating liver

scientific article published on 01 April 2003

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