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List of works by Claire T. Friel

A Cdk1 phosphomimic mutant of MCAK impairs microtubule end recognition

scientific article published on 6 December 2017

Analysing the ATP Turnover Cycle of Microtubule Motors

scientific article published on 01 January 2011

Comparison of the transition state ensembles for folding of Im7 and Im9 determined using all-atom molecular dynamics simulations with phi value restraints

scientific article (publication date: 15 February 2004)

Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex

scientific article published on 13 November 2019

Helix stability and hydrophobicity in the folding mechanism of the bacterial immunity protein Im9.

scientific article published in January 2005

Identification of key residues that regulate the interaction of kinesins with microtubule ends

scientific article published on 01 July 2019

Microtubule dynamics reconstituted in vitro and imaged by single-molecule fluorescence microscopy.

scientific article published on January 2010

Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.

scientific article published on December 2011

Parts list for a microtubule depolymerising kinesin

scientific article published on 22 November 2018

Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation

scientific article

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

scientific article

Purification of tubulin from porcine brain

scientific article published in January 2011

Semisynthesis of a glycosylated Im7 analogue for protein folding studies

scientific article published on September 2005

Structural analysis of the rate-limiting transition states in the folding of Im7 and Im9: similarities and differences in the folding of homologous proteins

scientific article

Switching two-state to three-state kinetics in the helical protein Im9 via the optimisation of stabilising non-native interactions by design.

scientific article published in September 2004

The effect of increasing the stability of non-native interactions on the folding landscape of the bacterial immunity protein Im9.

scientific article published on 10 May 2007

The family-specific α4-helix of the kinesin-13, MCAK, is critical to microtubule end recognition.

scientific article published on October 2016

The kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization.

scientific article

The mechanism of folding of Im7 reveals competition between functional and kinetic evolutionary constraints

scientific article published in March 2009

Use of stopped-flow fluorescence and labeled nucleotides to analyze the ATP turnover cycle of kinesins

scientific article

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