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List of works by Pedro A Sánchez-Murcia

2'-Deoxyribosyltransferase from Leishmania mexicana, an efficient biocatalyst for one-pot, one-step synthesis of nucleosides from poorly soluble purine bases.

scientific article published on 7 August 2017

A Series of Enthalpically Optimized Docetaxel Analogues Exhibiting Enhanced Antitumor Activity and Water Solubility

scientific article published on 23 January 2018

A Supramolecular Stabilizer of the 14-3-3ζ/ERα Protein-Protein Interaction with a Synergistic Mode of Action

scientific article published on 11 February 2020

A functional BH3 domain in an aquaporin from Leishmania infantum.

scientific article published on 04 July 2016

A novel C,D-spirodioxene taxoid synthesized through an unexpected Pd-mediated ring cyclization

scientific article published on 25 November 2015

Arginine mimetic appended peptide-based probes for fluorescence turn-on detection of 14-3-3 proteins

scientific article published on 01 April 2019

Cold-induced aldimine bond cleavage by Tris in Bacillus subtilis alanine racemase

scientific article published on 01 April 2019

Comparison of hydrocarbon-and lactam-bridged cyclic peptides as dimerization inhibitors of Leishmania infantum trypanothione reductase

scholarly article in RSC Advances, vol. 5 no. 69, 2015

Conservation of antiviral activity and improved selectivity in PMEO-DAPym upon pyrimidine to triazine scaffold hopping

scientific article published on 11 August 2015

DNA-binding mechanism of spiropyran photoswitches: the role of electrostatics

scientific article published on 01 April 2019

Directional and regioselective hole injection of spiropyran photoswitches intercalated into A/T-duplex DNA

scientific article published on 01 August 2019

Enantioselective oxidation of galactitol 1-phosphate by galactitol-1-phosphate 5-dehydrogenase from Escherichia coli

scientific article

Engineering Erg10 Thiolase from Saccharomyces cerevisiae as a Synthetic Toolkit for the Production of Branched-Chain Alcohols.

scientific article published on 23 January 2018

Enhanced Rigidity Changes Ultraviolet Absorption: Effect of a Merocyanine Binder on G-Quadruplex Photophysics

scientific article published on 18 November 2020

Enzymatic Synthesis of Therapeutic Nucleosides using a Highly Versatile Purine Nucleoside 2’-DeoxyribosylTransferase from Trypanosoma brucei

scholarly article by Elena Pérez et al published 9 August 2018 in ChemCatChem

Exciton Localization on Ru-Based Photosensitizers Induced by Binding to Lipid Membranes.

scientific article published on 24 January 2018

First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity

scientific article published on 13 April 2017

Formal asymmetric enone aminohydroxylation: organocatalytic one-pot synthesis of 4,5-disubstituted oxazolidinones

scientific article published on 16 May 2012

Functional Characterization and Structural Analysis of NADH Oxidase Mutants from Thermus thermophilus HB27: Role of Residues 166, 174, and 194 in the Catalytic Properties and Thermostability

scientific article published on 31 October 2019

Genome mining and characterisation of a novel transaminase with remote stereoselectivity

scientific article published on 30 December 2019

Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptides

scientific article

Making sense of the past: hyperstability of ancestral thioredoxins explained by free energy simulations

scientific article published on 21 August 2017

Modular Architecture and Unique Teichoic Acid Recognition Features of Choline-Binding Protein L (CbpL) Contributing to Pneumococcal Pathogenesis

scientific article

Molecular Interactions and Implications of Aldose Reductase Inhibition by PGA1 and Clinically Used Prostaglandins.

scientific article published on 20 October 2015

Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches

scientific article published on 25 February 2014

Orbital-free photophysical descriptors to predict directional excitations in metal-based photosensitizers

scientific article published on 15 May 2020

Photoactivation of channelrhodopsin

scientific article

Pro-death activity of a BH3 domain in an aquaporin from the protozoan parasite Leishmania.

scientific article published on 28 July 2016

Probing the dimerization interface of Leishmania infantum trypanothione reductase with site-directed mutagenesis and short peptides

scientific article published on 6 June 2013

Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase

scientific article published on 23 April 2019

Reaction mechanism of nucleoside 2'-deoxyribosyltransferases: free-energy landscape supports an oxocarbenium ion as the reaction intermediate

scientific article published on 01 August 2019

Restoration of Microtubule Interaction and Cytotoxicity in D-seco Taxanes upon Incorporation of 20-Hydroxymethyl-4-allyloxy Groups

scientific article published on 09 December 2015

Stepwise Simulation of 3,5-Dihydro-5-methylidene-4H-imidazol-4-one (MIO) Biogenesis in Histidine Ammonia-lyase

scientific article published on 29 September 2016

Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.

scientific article published on 13 December 2016

Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B.

scientific article published on 12 September 2017

Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences.

scientific article published on September 2017

Synthesis and evaluation of hybrid molecules targeting the vinca domain of tubulin

scientific article

Translation Elongation Factor eEF1A2 is a Novel Anticancer Target for the Marine Natural Product Plitidepsin.

scientific article published on 7 October 2016

Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability.

scientific article published on 24 February 2018

Unravelling the covalent binding of zampanolide and taccalonolide AJ to a minimalist representation of a human microtubule

scientific article published on 31 May 2019

Unveiling the reaction mechanism of novel copper N-alkylated tetra-azacyclophanes with outstanding superoxide dismutase activity

scientific article published on 08 June 2020

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