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List of works by Vinayaka R. Prasad

A Naturally Occurring Polymorphism in the HIV-1 Tat Basic Domain Inhibits Uptake by Bystander Cells and Leads to Reduced Neuroinflammation

article

Analysis of 2-LTR circle junctions of viral DNA in infected cells

scientific article

Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function

scientific article

Anti-HIV inhibitors based on nucleic acids: emergence of aptamers as potent antivirals

scientific article published on December 2003

Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication

scientific article

CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release.

scientific article

Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence.

scientific article published on 08 June 2013

Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase.

scientific article

Effects of mutations in Pr160gag-pol upon tRNA(Lys3) and Pr160gag-plo incorporation into HIV-1.

scientific article published in January 1997

Evaluating the Role of Viral Proteins in HIV-Mediated Neurotoxicity Using Primary Human Neuronal Cultures

scientific article published on January 2016

Examining Interactions of HIV-1 Reverse Transcriptase with Single-stranded Template Nucleotides by Nucleoside Analog Interference

scientific article published in Journal of Biological Chemistry

Exceptional molecular and coreceptor-requirement properties of molecular clones isolated from an Human Immunodeficiency Virus Type-1 subtype C infection

scientific article published on 7 March 2008

Expression of enzymatically active reverse transcriptase of simian immunodeficiency virus in bacteria: sensitivity to nucleotide analogue inhibitors

scientific article published in December 1990

Genetic characterization of HIV type 1 Tat exon 1 from a southern Indian clinical cohort: identification of unique epidemiological signature residues

scientific article

HIV-1 clade-specific differences in the induction of neuropathogenesis

scientific article published in October 2008

HIV-1 reverse transcriptase mutations that confer decreased in vitro susceptibility to anti-RT DNA aptamer RT1t49 confer cross resistance to other anti-RT aptamers but not to standard RT inhibitors

scientific article

High-affinity RNA Aptamers Against the HIV-1 Protease Inhibit Both In Vitro Protease Activity and Late Events of Viral Replication

scientific article published on 17 February 2015

Human telomerase RNA template sequence is a determinant of telomere repeat extension rate

scientific article published in August 2005

INI1/hSNF5-interaction defective HIV-1 IN mutants exhibit impaired particle morphology, reverse transcription and integration in vivo

scientific article published on 24 June 2013

Influence of naturally occurring insertions in the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase on polymerase fidelity and mutation frequencies in vitro

scientific article published on February 2006

Insertions into the β3-β4 Hairpin Loop of HIV-1 Reverse Transcriptase Reveal a Role for Fingers Subdomain in Processive Polymerization

scientific article published in Journal of Biological Chemistry

Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter

scientific article

Interaction between human immunodeficiency virus type 1 reverse transcriptase and integrase proteins

scientific article published on May 2004

Isolation and characterization of binding proteins for retinol from the cytosol, nucleosol and chromatin of the oviduct magnum of laying hens ⬇️

scientific article published on December 1, 1979

K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies

scientific article published on 09 June 2010

Long-term amelioration of bilirubin glucuronidation defect in Gunn rats by transplanting genetically modified immortalized autologous hepatocytes

scientific article published in November 1998

Lys66 residue as a determinant of high mismatch extension and misinsertion rates of HIV-1 reverse transcriptase

scientific article

Macrophage inflammatory markers are associated with subclinical carotid artery disease in women with human immunodeficiency virus or hepatitis C virus infection

scientific article

Measuring the Uptake and Transactivation Function of HIV-1 Tat Protein in a Trans-cellular Cocultivation Setup

scientific article published on January 2016

Methods to study monocyte migration induced by HIV-infected cells

scientific article

Multivariable analysis to determine if HIV-1 Tat dicysteine motif is associated with neurodevelopmental delay in HIV-infected children in Malawi

scientific article

Mutations proximal to the minor groove-binding track of human immunodeficiency virus type 1 reverse transcriptase differentially affect utilization of RNA versus DNA as template

scientific article

Mutations that confer resistance to template-analog inhibitors of human immunodeficiency virus (HIV) type 1 reverse transcriptase lead to severe defects in HIV replication

scientific article published on April 2002

New clues to understanding HIV nonprogressors: low cholesterol blocks HIV trans infection

scientific article

Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patients.

scientific article

Nucleoside-analog resistance mutations in HIV-1 reverse transcriptase and their influence on polymerase fidelity and viral mutation rates

scientific article published on September 2004

Phylogenetic characterization of six full-length HIV-1 subtype C molecular clones from three patients: identification of rare subtype C strains containing two NF-κB motifs in the long terminal repeat

scientific article

Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment).

scientific article published on July 2002

Pre-steady state kinetic analysis of cyclobutyl derivatives of 2'-deoxyadenosine 5'-triphosphate as inhibitors of HIV-1 reverse transcriptase

scientific article

Probing the active site steric flexibility of HIV-1 reverse transcriptase: different constraints for DNA- versus RNA-templated synthesis

scientific article

Purification of a retinol binding protein from the hen-oviduct cytosol and its immunological cross-reactivity with those from the nucleus

scientific article published on 01 October 1983

RNA aptamers directed to human immunodeficiency virus type 1 Gag polyprotein bind to the matrix and nucleocapsid domains and inhibit virus production

scientific article

Site-directed mutagenesis in the fingers subdomain of HIV-1 reverse transcriptase reveals a specific role for the beta3-beta4 hairpin loop in dNTP selection

scientific article published on 27 September 2006

Structural determinants of slippage-mediated mutations by human immunodeficiency virus type 1 reverse transcriptase

scientific article

Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase

scientific article published on August 2006

Structural requirements for bacterial expression of stable, enzymatically active fusion proteins containing the human immunodeficiency virus reverse transcriptase

scientific article published in July 1988

Structure-Function Studies of HIV Reverse Transcriptase ⬇️

scientific article published on January 1, 1990

Substitutions at Phe61 in the beta3-beta4 hairpin of HIV-1 reverse transcriptase reveal a role for the Fingers subdomain in strand displacement DNA synthesis

scientific article

Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase

scientific article

T-h-2 immunity and CD3+CD45RBlow-activated T cells in mice immunized with recombinant bacillus Calmette-Guérin expressing HIV-1 principal neutralizing determinant epitope.

scientific article published in June 2006

Tat protein of human immunodeficiency virus type 1 subtype C strains is a defective chemokine

scientific article published on March 2004

The Evolving Profile of the Signature Amino Acid Residues in HIV-1 Subtype C Tat.

scientific article published on 18 December 2015

The active site residue Valine 867 in human telomerase reverse transcriptase influences nucleotide incorporation and fidelity

scientific article published on 30 January 2007

The effect of increased processivity on overall fidelity of human immunodeficiency virus type 1 reverse transcriptase

scientific article published in March 2001

The gp120 protein is a second determinant of decreased neurovirulence of Indian HIV-1C isolates compared to southern African HIV-1C isolates

scientific article

The influence of 3TC resistance mutation M184I on the fidelity and error specificity of human immunodeficiency virus type 1 reverse transcriptase ⬇️

scientific article published on June 15, 1998

The influence of 3TC-resistance mutations E89G and M184V in the human immunodeficiency virus reverse transcriptase on mispair extension efficiency ⬇️

scientific article published on October 1, 1998

The lysine 65 residue in HIV-1 reverse transcriptase function and in nucleoside analog drug resistance

scientific article

The telomerase-specific T motif is a restrictive determinant of repetitive reverse transcription by human telomerase

scientific article

Utilization of a deoxynucleoside diphosphate substrate by HIV reverse transcriptase

scientific article published on 30 April 2008

Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND)

scientific article published on 19 May 2014

Virtues of being faithful: can we limit the genetic variation in human immunodeficiency virus?

scientific article published in August 1998

[28] Linker insertion mutagenesis as probe of structure-function relationships

scientific article published on 01 January 1991

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