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List of works by Christopher J. Weir

A pragmatic, multi-centered, stepped wedge, cluster randomized controlled trial pilot of the clinical and cost effectiveness of a complex Stroke Oral healthCare intervention pLan Evaluation II (SOCLE II) compared with usual oral healthcare in stroke

scientific article published on 30 September 2019

A randomised, controlled pilot study to investigate the potential benefit of intervention with insulin in hyperglycaemic acute ischaemic stroke patients

scientific article

Allopurinol and nitric oxide activity in the cerebral circulation of those with diabetes: a randomized trial

scientific article published on 22 October 2008

Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent ischemic stroke: a randomized, double-blind, placebo-controlled trial

scientific article

Associations between meteorological variables and acute stroke hospital admissions in the west of Scotland

scientific article

Baseline serum urate and 90-day functional outcomes following acute ischemic stroke.

scientific article published on 30 June 2009

Bronchial nitric oxide flux (J'aw) is sensitive to oral corticosteroids in smokers with asthma

scientific article published on 12 August 2011

Categorizing stroke prognosis using different stroke scales

scientific article published on 06 August 2009

Clinical and cost effectiveness of enhanced oral healthcare in stroke care settings (SOCLE II): a pilot, stepped wedge, cluster randomized, controlled trial protocol.

scientific article

Clinical relevance and practical implications of trials of perfusion and angiographic imaging in patients with acute ischaemic stroke: a multicentre cohort imaging study

scientific article published on 03 May 2013

Clinical validity of plasma and urinary desmosine as biomarkers for chronic obstructive pulmonary disease.

scientific article

Cluster-randomized, controlled trial of computer-based decision support for selecting long-term anti-thrombotic therapy after acute ischaemic stroke

scientific article published on 01 February 2003

Comparison of mean cerebral transit time and single-photon emission tomography for estimation of stroke outcome

scientific article published on 01 November 1995

Comparison of non-traditional biomarkers, and combinations of biomarkers, for vascular risk prediction in people with type 2 diabetes: The Edinburgh Type 2 Diabetes Study

scientific article published on 12 July 2017

Comparison of stratification and adaptive methods for treatment allocation in an acute stroke clinical trial

scientific article published in March 2003

Comparison of the National Institutes of Health Stroke Scale with disability outcome measures in acute stroke trials

scientific article published on 22 September 2005

Current recommendations/practices for anonymising data from clinical trials in order to make it available for sharing: A scoping review

scientific article published on 22 June 2022

Death after head injury: the 13 year outcome of a case control study

scientific article published on 31 January 2011

Design and analysis of phase III trials with ordered outcome scales: the concept of the sliding dichotomy

scientific article

Does the prevention of complications explain the survival benefit of organized inpatient (stroke unit) care?: further analysis of a systematic review.

scientific article published on 9 August 2007

Effect of apolipoprotein E genotype on in-hospital mortality following intracerebral haemorrhage

scientific article published on 01 February 2003

Effect of area-based deprivation on the severity, subtype, and outcome of ischemic stroke

scientific article

Effect of blood pressure during the acute period of ischemic stroke on stroke outcome: a tertiary analysis of the GAIN International Trial

scientific article published on 18 September 2003

Effect of smoking status on outcome after acute ischemic stroke

scientific article published on 27 January 2006

Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma

scientific article published on 29 August 2008

Effects of intrathecal administration of a cell permeant caspase inhibitor, boc-D-fluoromethylketone (BDFMK), on behavioral deficits following spinal cord ischemia: a dose-response analysis

scientific article

Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats

scientific article published on 3 January 2008

Effects of short-term treatment with atorvastatin in smokers with asthma--a randomized controlled trial

scientific article

Elevated serum urate concentration independently predicts poor outcome following stroke in patients with diabetes.

scientific article published on January 2006

Evaluating improvement interventions using routine data to support a learning health system: research design, data access, analysis and reporting

scientific article published on 25 February 2020

FAST INdiCATE Trial protocol. Clinical efficacy of functional strength training for upper limb motor recovery early after stroke: neural correlates and prognostic indicators

scientific article

Factors associated with outcome and duration of therapy in outpatient parenteral antibiotic therapy (OPAT) patients with skin and soft-tissue infections

scientific article published on 7 July 2011

Flexible design and efficient implementation of adaptive dose-finding studies

scientific article published in January 2007

Functional strength training versus movement performance therapy for upper limb motor recovery early after stroke: a RCT

article by Valerie M Pomeroy et al published June 2018 in Efficacy and Mechanism Evaluation

Future Care Planning for patients approaching end-of-life with advanced heart disease: an interview study with patients, carers and healthcare professionals exploring the content, rationale and design of a randomised clinical trial

scientific article

Head injury attenders in the emergency department: the impact of advice and factors associated with early symptom outcome

scientific article published in June 2009

High-sensitivity cardiac troponin and the diagnosis of myocardial infarction in patients with kidney impairment

Improving the efficiency of stroke trials: feasibility and efficacy of group adjudication of functional end points.

scientific article

Improving trial power through use of prognosis-adjusted end points

scientific article published on 20 January 2005

Induction of labour in nulliparous and multiparous women: a UK, multicentre, open-label study of intravaginal misoprostol in comparison with dinoprostone

scientific article

Inter-relationships between spinal cord blood flow, neuronal death and neurological function in rabbit spinal cord ischemia

scientific article published in August 2002

Is informal caregiving independently associated with poor health? A population-based study.

scientific article published on 8 August 2012

Low triglyceride, not low cholesterol concentration, independently predicts poor outcome following acute stroke

scientific article published in January 2003

Low-dose dexamethasone as a treatment for women with heavy menstrual bleeding: protocol for response-adaptive randomised placebo-controlled dose-finding parallel group trial (DexFEM).

scientific article

Magnesium for treatment of acute lacunar stroke syndromes: further analysis of the IMAGES trial.

scientific article published on 8 March 2007

Mortality and morbidity 15 years after hospital admission with mild head injury: a prospective case-controlled population study

scientific article published on 12 March 2014

Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease

scientific article published in 2022

N-terminal pro-brain natriuretic peptide and risk of cardiovascular events in older patients with type 2 diabetes: the Edinburgh Type 2 Diabetes Study

scientific article published on 18 September 2014

NAA is a Marker of Disability in Secondary-Progressive MS: A Proton MR Spectroscopic Imaging Study

scientific article published on 05 November 2020

Non-adjustment for multiple testing in multi-arm trials of distinct treatments: Rationale and justification

scientific article published on 15 July 2020

Noninvasive MRI Measurement of CBF: Evaluating An Arterial Spin Labelling Sequence with 99mTc-HMPAO CBF Autoradiography in a Rat Stroke Model ⬇️

scientific article published on April 4, 2012

Pneumonia and urinary tract infection after acute ischaemic stroke: a tertiary analysis of the GAIN International trial

scientific article published in January 2004

Poor accuracy of stroke scoring systems for differential clinical diagnosis of intracranial haemorrhage and infarction

scientific article published in The Lancet

Population-based trends in pregnancy hypertension and pre-eclampsia: an international comparative study

scientific article

Poststroke neurological improvement within 7 days is associated with subsequent deterioration

scientific article published on 8 July 2004

Predictors of upper limb recovery after stroke: a systematic review and meta-analysis.

scientific article published on 24 October 2011

Prescription of emergency antiepileptic medication after a first childhood seizure: analysis of routine administrative data

scientific article

Principles of dose finding studies in cancer: a comparison of trial designs.

scientific article published on 9 January 2013

Prognostic value of single-photon emission tomography in acute ischaemic stroke

scientific article published in January 1997

Protocol for the development of SPIRIT and CONSORT extensions for randomised controlled trials with surrogate primary endpoints: SPIRIT-SURROGATE and CONSORT-SURROGATE

scientific article published on 11 October 2022

Randomised controlled trial of azithromycin in smokers with asthma

scientific article published on 13 September 2013

Randomised controlled trial of combined spinal epidural vs. spinal anaesthesia for elective caesarean section: vasopressor requirements and cardiovascular changes.

scientific article published in January 2009

Results of the MRI substudy of the intravenous magnesium efficacy in stroke trial.

scientific article published on 19 March 2009

Scoping and targeted reviews to support development of SPIRIT and CONSORT extensions for randomised controlled trials with surrogate primary endpoints: protocol

scientific article published on 13 October 2022

Sensitive troponin assay predicts outcome in syncope

scientific article published on 8 September 2012

Serum urate as an independent predictor of poor outcome and future vascular events after acute stroke.

scientific article published on 3 July 2003

Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines-an exploratory study

scientific article

Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity.

scientific article

Statin administration prior to ischaemic stroke onset and survival: exploratory evidence from matched treatment-control study

scientific article published in July 2005

Strengthening acute stroke trials through optimal use of disability end points

scientific article published on 16 October 2003

Stroke education for healthcare professionals: making it fit for purpose

scientific article published on 18 September 2007

Targeting neuroprotection clinical trials to ischemic stroke patients with potential to benefit from therapy

scientific article published on 8 July 2004

The 4 'A's test for detecting delirium in acute medical patients: a diagnostic accuracy study

scientific article published on 01 August 2019

The Glasgow Outcome at Discharge Scale: an inpatient assessment of disability after brain injury.

scientific article published on 5 June 2013

The Modified Graeb Score: an enhanced tool for intraventricular hemorrhage measurement and prediction of functional outcome.

scientific article

The Virtual International Stroke Trials Archive.

scientific article published on 19 April 2007

The association of post-stroke neurological improvement with risk of subsequent deterioration due to stroke events

scientific article published on 01 January 2007

The evidence-base for stroke education in care homes.

scientific article published on 18 April 2008

The prognostic significance of visible infarction on computed tomography following lacunar stroke: results of a long-term follow-up study

scientific article published in October 2005

The prognostic value of the components of the Glasgow Coma Scale following acute stroke.

scientific article

The role of methadone in drug-related deaths in the west of Scotland

scientific article published in July 2003

Timing of birth and risk of multiple sclerosis in the Scottish population

scientific article published on 23 December 2009

Urinary catheterization in acute stroke: clinical realities. A mixed methods study.

scientific article

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