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List of works by Frederik De Smet

Aggregation gatekeepers modulate protein homeostasis of aggregating sequences and affect bacterial fitness

scientific article published on 15 June 2012

Allosteric targeting of receptor tyrosine kinases.

scientific article published in November 2014

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

scientific article published on 01 January 2020

De novo design of a biologically active amyloid.

scientific article

Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin

scientific article

Endothelial oxygen sensors regulate tumor vessel abnormalization by instructing phalanx endothelial cells.

scientific article published on 20 May 2009

FGF-dependent metabolic control of vascular development

scientific article published on 3 May 2017

Fibroblast growth factor signaling affects vascular outgrowth and is required for the maintenance of blood vessel integrity

scientific article published on 4 September 2014

Fishing and frogging for anti-angiogenic drugs

scientific article published on 01 May 2006

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

Gene prioritization through genomic data fusion

scientific article published in May 2006

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization

scientific article

Immunocompetent Mouse Models in the Search for Effective Immunotherapy in Glioblastoma

scientific article published on 23 December 2020

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

scientific article

Linking single-cell measurements of mass, growth rate, and gene expression

article

Mechanisms of vessel branching: filopodia on endothelial tip cells lead the way.

scientific article published on 05 March 2009

Molecular Mechanism of SSR128129E, an Extracellularly Acting, Small-Molecule, Allosteric Inhibitor of FGF Receptor Signaling

Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling

scientific article

Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.

scientific article published on 30 December 2016

Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish.

scientific article published on 13 May 2010

Role of synectin in lymphatic development in zebrafish and frogs

scientific article published on 14 July 2010

Sequence-Specific Protein Aggregation Generates Defined Protein Knockdowns in Plants

scientific article published on 4 May 2016

Sequence-dependent internalization of aggregating peptides

scientific article

Structural hot spots for the solubility of globular proteins.

scientific article

The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system

scientific article published on 27 October 2004

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

scientific article published in August 2003

VEGF: a modifier of the del22q11 (DiGeorge) syndrome?

scientific article published on 21 January 2003