List of works - Towia A Libermann

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

scientific article (publication date: March 2003)

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

scientific article published in Nature

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

scientific article

Soluble endoglin contributes to the pathogenesis of preeclampsia

scientific article (publication date: June 2006)

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor

scientific journal article

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

scientific article published in January 1985

Molecular sequelae of proteasome inhibition in human multiple myeloma cells

scientific article

The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications

scientific article published on 7 November 2002

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications

scientific article published on 26 December 2003

Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors

scientific article published in March 2004

Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

scientific article published on April 1999

Gene signatures of progression and metastasis in renal cell cancer

scientific article published on 01 August 2005

Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells

scientific article published on February 2003

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4

scientific article

Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma–associated herpesvirus

A high-fat, ketogenic diet induces a unique metabolic state in mice

scientific article published on 13 February 2007

Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide.

scientific article published on July 1994

Antimyeloma activity of heat shock protein-90 inhibition.

scientific article published on 18 October 2005

Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B

scientific article published on 01 February 1996

Comment on " 'Stemness': transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature"

scientific article published on 01 October 2003

Expression of epidermal growth factor receptors in human brain tumors

scientific article published in February 1984

Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor

scientific article

Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines

scientific article published on July 1988

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family

scientific article

A metabolic prosurvival role for PML in breast cancer.

scientific article

PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression

scientific article

Gene expression signature with independent prognostic significance in epithelial ovarian cancer

scientific article published on 25 October 2004

GADD45 proteins: central players in tumorigenesis

scientific article

Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice.

scholarly article

ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization, and differential expression during B-lymphocyte development

scientific article published on May 1994

Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells

scientific article published on 15 October 2006

Serum proteomics and biomarkers in hepatocellular carcinoma and chronic liver disease

scientific article

Genomic counter-stress changes induced by the relaxation response

scientific article

A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions

scientific article

Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer

scientific article

Adenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-kappaB.

scientific article published on May 2000

Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells.

scientific article published on January 2006

NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival

scientific article

Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies

scientific article

Relaxation response induces temporal transcriptome changes in energy metabolism, insulin secretion and inflammatory pathways

scientific article

Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer.

scientific article published in May 2003

Prediction of diabetic nephropathy using urine proteomic profiling 10 years prior to development of nephropathy

scientific article published in March 2007

ESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1

scientific article

Targeting transcription factors for cancer gene therapy.

scientific article

Unique gene expression profile based on pathologic response in epithelial ovarian cancer

scientific article

Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response

scientific article published on February 1998

Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes

scientific article

An angiogenic growth factor is expressed in human glioma cells.

scientific article published on June 1987

Nucleoside triphosphate diphosphohydrolase-2 (NTPDase2/CD39L1) is the dominant ectonucleotidase expressed by rat astrocytes

scientific journal article

List of works by Towia A Libermann

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

Soluble endoglin contributes to the pathogenesis of preeclampsia

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Molecular sequelae of proteasome inhibition in human multiple myeloma cells

The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications

Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors

Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

Gene signatures of progression and metastasis in renal cell cancer

Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4

Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma–associated herpesvirus

A high-fat, ketogenic diet induces a unique metabolic state in mice

Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide.

Antimyeloma activity of heat shock protein-90 inhibition.

Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B

Comment on " 'Stemness': transcriptional profiling of embryonic and adult stem cells" and "a stem cell molecular signature"

Expression of epidermal growth factor receptors in human brain tumors

Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor

Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family

A metabolic prosurvival role for PML in breast cancer.

PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression

Gene expression signature with independent prognostic significance in epithelial ovarian cancer

GADD45 proteins: central players in tumorigenesis

Curative and beta cell regenerative effects of alpha1-antitrypsin treatment in autoimmune diabetic NOD mice.

ERP, a new member of the ets transcription factor/oncoprotein family: cloning, characterization, and differential expression during B-lymphocyte development

Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells

Serum proteomics and biomarkers in hepatocellular carcinoma and chronic liver disease

Genomic counter-stress changes induced by the relaxation response

A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions

Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer

Adenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-kappaB.

Differential gene expression analysis reveals generation of an autocrine loop by a mutant epidermal growth factor receptor in glioma cells.

NF-κB-mediated repression of growth arrest- and DNA-damage-inducible proteins 45α and γ is essential for cancer cell survival

Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies

Relaxation response induces temporal transcriptome changes in energy metabolism, insulin secretion and inflammatory pathways

Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer.

Prediction of diabetic nephropathy using urine proteomic profiling 10 years prior to development of nephropathy

ESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1

Targeting transcription factors for cancer gene therapy.

Unique gene expression profile based on pathologic response in epithelial ovarian cancer

Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response

Characterization of ESE-2, a novel ESE-1-related Ets transcription factor that is restricted to glandular epithelium and differentiated keratinocytes

An angiogenic growth factor is expressed in human glioma cells.

Nucleoside triphosphate diphosphohydrolase-2 (NTPDase2/CD39L1) is the dominant ectonucleotidase expressed by rat astrocytes