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List of works by Jason A. Howitt

A molecular mechanism for the heparan sulfate dependence of slit-robo signaling

scientific article

BDNF exerts contrasting effects on peripheral myelination of NGF-dependent and BDNF-dependent DRG neurons.

scientific article

Differential regulation of Nedd4 ubiquitin ligases and their adaptor protein Ndfip1 in a rat model of ischemic stroke

scientific journal article

Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons

scientific article

Engineered Exosomes as Vehicles for Biologically Active Proteins

scientific article published on 13 April 2017

Exosomes in the Pathology of Neurodegenerative Diseases

scientific article published on 16 November 2016

Increased Ndfip1 in the substantia nigra of Parkinsonian brains is associated with elevated iron levels

scientific article published on 24 January 2014

Initiation and Transmission of α-Synuclein Pathology in Parkinson's Disease

scientific article published on 11 November 2019

Interaction of the guidance molecule Slit with cellular receptors.

scientific article

Ndfip1 expression in developing neurons indicates a role for protein ubiquitination by Nedd4 E3 ligases during cortical development

scientific article published on 13 September 2013

Ndfip1 is required for the development of pyramidal neuron dendrites and spines in the neocortex

scientific article published on 29 July 2013

Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells

scientific article published on 13 January 2014

Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia

scientific article published on 2 January 2012

Ndfip1 represses cell proliferation by controlling Pten localization and signaling specificity

scientific article

Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response

scientific article

Nedd4 family-interacting protein 1 (Ndfip1) is required for the exosomal secretion of Nedd4 family proteins

scientific article published on 25 September 2008

Nedd4-WW domain-binding protein 5 (Ndfip1) is associated with neuronal survival after acute cortical brain injury.

scientific article

Nuclear trafficking of Pten after brain injury leads to neuron survival not death.

scientific article published on 22 November 2013

PTEN secretion in exosomes.

scientific article published on 24 December 2014

Protein aggregation during overexpression limited by peptide extensions with large net negative charge

scientific article published in August 2004

Rab5 and Ndfip1 are involved in Pten ubiquitination and nuclear trafficking

scientific article

Structural and Functional Analysis of Slit and Heparin Binding to Immunoglobulin-like Domains 1 and 2 of Drosophila Robo

scientific article

Structural basis for variation in adenovirus affinity for the cellular coxsackievirus and adenovirus receptor

scientific article (publication date: 11 July 2003)

The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8+ T Cell Tolerance Checkpoint to High-Dose Antigen

scientific article published on 01 July 2018

The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells

scientific article published on 25 September 2012

Ubiquitin Regulation of Trk Receptor Trafficking and Degradation

scientific article published on 18 June 2018

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